Htri018575.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Hirtodrosophila trivittata
Gene Symbol
L
Assembly
GCA_035045065.1
Location
JAWNNK010001311.1:18325514-18334003[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 1e-05 0.00088 19.9 2.9 1 23 156 178 156 178 0.98
2 16 0.36 30 5.6 6.2 1 23 184 206 184 206 0.97
3 16 1.7e-07 1.5e-05 25.5 3.2 1 23 212 234 212 234 0.99
4 16 1.3e-05 0.0011 19.6 0.4 1 23 240 262 240 262 0.99
5 16 0.013 1.1 10.1 0.1 2 23 341 365 340 365 0.93
6 16 0.00077 0.065 14.0 0.4 2 23 393 415 392 415 0.94
7 16 0.028 2.4 9.1 0.7 1 23 498 520 498 520 0.97
8 16 0.0072 0.6 11.0 0.2 2 23 528 549 527 549 0.91
9 16 3.7e-05 0.0031 18.2 0.3 1 23 557 581 557 581 0.95
10 16 0.0026 0.22 12.4 1.1 1 23 687 710 687 710 0.97
11 16 0.0017 0.14 13.0 1.8 2 23 879 901 878 901 0.96
12 16 0.12 9.8 7.1 0.1 1 23 907 929 907 929 0.92
13 16 0.34 29 5.7 0.7 2 23 937 958 936 958 0.95
14 16 0.76 64 4.6 0.5 2 23 1054 1075 1054 1075 0.94
15 16 0.032 2.7 8.9 0.0 1 23 1085 1107 1085 1107 0.96
16 16 0.00023 0.019 15.7 1.2 1 23 1112 1134 1112 1134 0.97

Sequence Information

Coding Sequence
ATGGCCCTAAAAATGTTATATCGCGGTCCCAGTTCGCGTTTGGAGAATTTAATAGAAAAGATTCAAGCAACAAAGGAGATAACAAATAACGATATGTACAGCACGCACACCTCCTCCAGCTACTCGCCCAGCATCTCGGATGGCACATTGACGCCTAACTCACATCAGCAGCTGGCGCTGGGTAGCCATCCGCCAGCAGCCGAGGATGCCTCAGCGGAGGAGGCGAAGGCGAATGGGGAGACGTCGTCGGAGCAGCTAGAGCAGCCAATGAAGCCAAAGCGTCCCTCCcatttccatcatcatcatcatcattatcaccATCAGCAGGCACTGAAAATTGCCAACAAGCTGCGCAAGATGAACAAGGAAGCGAAGCTAGCGGCTGCCACAGCACCTGGCCACGGTGCAGCCACAAAGTTTGATAAGTTGACAGGCGAGGGCATTAAGAGTCGCACCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCACGACTCGGCTACTTGAAGCATCACGTTCAGAGTCACGCCGAGCATCTTCCCTTCAAGTGCGAATACTGCGCCAAACTATTCAAGCACAAACGCTCCAGGGATCGCCATAAGAAGCTCCACACCAACGAGAGGAACTACAAGTGTCCTCACTGCGAGGCAGCTTTCTCCAGAAGCGACCATCTGAAGATTCACATGAAGACGCACGATATCCAGAAGCCGTTCCAGTGCAGCATGTGCAACAGGGGCTACAACACGGCTGCCGCGTTGACCTCCCACATGCAGAAGCACAAGAAGAATGCGGCGATTCTCGCAGCTGGCGGCAATCCCAATGCACTCAACTATAGTCCACGCTCGACGGGATCAGCCTCCATCTCGAGCAATGGCAGTCTGCACAAGCGTCGCTATGCGCTGGCACTCGCCTCCGATAGCAGTCCCAGTCGCCTGGAGTTTCCGAAGCGGGCACGTGCTCACTTGAGTCAAGCGAATCATGTGGCCAATACGCCCACTCCGACTCCTTTGCTGCGCTGCAGCTACTGTCCCAAGGCGACGGAGTTCAGCAGCTTGGAGCAGCTTAATGCCCACCTCCAGAGCGCACACGAGCAGCAGGTGAGGAGCTCCAGCGCCACAGCGACGACTGCAGCTGGAGAGGCAGAGCCACAGGCCAACGGCTTCCAGCTGAACTGCGAGTACTGCACGATGAAGTTTGGGAACATAGCCAATCTCTTCCAGCATATGCGTGGCACACACTTGGATCGGCTGAGCAGTCCCAACTCCTACTATGAGCACTTCAATCGTCTGGCCACGGCGGGCACATTCAGCCCTCGGCTGGCTCTGGATCTGCCCAAGATCAAGCCGGATCTGTGCAGTCCGCAGCGGGAGCAGCCTACGGAGAAGCCGGAGCAGGAGCTGCCCACCGATTTGAGCAGCAACAAGCGACGCACAATGACACCACCGGAGCCACCACAGCCCGCTGCACCTGCTCCACCCGGCATCTTCTTCTGCAATCAATGCAACGCGGGTCTGCCGGACTTTGAGAGCTTCCGGAATCATCTGAAGACACATATAGCCGAAGGGATGCAGCTGATCTGTCCACATTGCGGCATCTGTCTGCCCGAGCAGAGCGAGTATGAACGCCATGTCGTTGCCCACTTTCTGATCACCAGCTCCGAGTTCAACTGCAGCGCCAGCTGCGGCAAATCCTTTGCCAAATCGGACGAACTGCAGCAGCATCTCAACAGCGAGCATGTGCTCACCCTGCTGAAGTGTGCCCTCTGCTCGGAGCTCTGCGAGTCCCGCATGGCCATGCAGCTCCATCTGGCCTGTGCCCACAGCCAGGAGACGAAGCTGCTCCGTTGCAGCGCCTGCATGGAGCTCTTCCGCAACGACACCGACTTCCATGTCCACGTCAAGACGCGTCATCAGCTGGGCAACCCGTCTGCAGGTGTTGGTCCTCCCGGTGCTGCTCCTGGTCCAGCCAATCCGCTGCAGTGCATGTTTTGTCGCGCTGTCTGCGCCTCCGAGCTGGAGATGCACTTCCACCTGGCGGCCCATGCCAGACAATTCCGCTGCCCCTCCTGTCCCGAGACCTTCCACGTGGAGTTCCTGCTGGACAGGCACATGCAGAGCCAGCATGGCGGCCTCAAGGACAAGGAGCCCAGCTCACCCAACATGGGCAGCCTCTATGTAAACGCCCTGCTCCCACCACTCgctgccgccgcagcagctgctgccgctgccaccaacaacaacagcaacctgCACATCGACTACAACGTCGCCTTCAAGGGTCTCTTTGGAGCTGGTGCCGCACCAGCCAGTGCTCAGCCTGGTAGCCAGAAGTTCTACAGTCCACTCCAGGTGGACACCAGTGGACTGAAGCCTCAGCAGTCGCCACATCCCGCGCTGATGTACGGCCTGAGCCAACGCTATCTGATGGAGATGTATGCGGCGAAGGCGACTTCCCCGGCGGCCAGTGCACCGGAGGTGCCTGTCCAGGCGAGCCAGGTGAATGCCACAGCCTCCAGTGCTGGGAGCAGCTACAGCTGCGGCATGTGCGAGCGGCAGGATCTGCGCAGCGAGGCAGAGCTCCACTCACATCGCAAGTTGGCCCACAATCTGAAGACTGGCGTCAGCTTGAGATGTGCCTATTGCTCGGGCAACTTTAAGTCCAGGgcggagctggagcagcacaTGAAGAGCTGCCACAACTCGAGTGGCAAGCATAAGTGTCTCATCTGTGACGAGATCTTTCCCTCGCCGGCCATCCTGGCCGAGCACAAACTGCAGCACTCCAAGGTGGGGCAGTCCGGCAAGTGCGCCCACTGTGGCCAGCAGCTGGAGCATGTGGCCGCCTTCCGTGCCCATCTCACCGAGCATGGAGGCGATGGCAATCTGCCCATGGCCTGCATCTGCTGCCGCCAGACGCTCCACTCCGAGTTCGAGCTCAGCTTACATGCCAAGTTCCATACGAAGTCGCCCTCTGGCTCTGGCAGCCTCCAGGAGCCCGTCTGTGCCCTCTGCCTGGAGCCGCTACCCGAGGCCGGAGAAACCGCCAAGCTCTGCGAGAAATGCTGTCGCAAGCACAATCTGAATGGGAAACGCAGCAAGGATCCGCCTCCACTGGTGCTGCCTGCTCCAAGCTCTAACGCCTATCTGGAGAATCGTTGTAATCTCTGCAAGATGATTCTGCCCCATGCACAGAAGCTCCAGGAGCATCTGGTGGAGCACACCTTTGCCGGTACCGAGCAACGCGGCTTCAATTGCTACATCTGCTCCGCGGTCTTCACAGCGCCCGCTGGCCTGCTGACCCACATTGCCGAGCACGGAGCACGTCCCTATGACTGCAATCTCTGCCCGGAGAAGTTCTACTTCCGCGCCGAACTCGAGCATCATCAGCGCGCCCACGAGCTGCGACCACCGCCGCCTCTGCCAGgacgcaacagcagcatcaccCAGCAGCCCAAGCAGGAGCCACTGCATGGAGCCAGCTCCACGGCCAGTTCACCACATCTCGCGATGAGCCCCAGCCATGTCAAGCAGGAGCTGTATGAGTCGGAGGCGGCCTCGCCCTcgcccagcagcagcgatCCTCCCGCACAGGAGGATGAGGAGTACATCGAGGTGGAGCAGGTGCCGCACGAGACACGCTCCGATGAGCTACTAAGTGCTGCACACACCGACCgttccagcagcagcgcctAA
Protein Sequence
MALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSHQQLALGSHPPAAEDASAEEAKANGETSSEQLEQPMKPKRPSHFHHHHHHYHHQQALKIANKLRKMNKEAKLAAATAPGHGAATKFDKLTGEGIKSRTDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEFPKRARAHLSQANHVANTPTPTPLLRCSYCPKATEFSSLEQLNAHLQSAHEQQVRSSSATATTAAGEAEPQANGFQLNCEYCTMKFGNIANLFQHMRGTHLDRLSSPNSYYEHFNRLATAGTFSPRLALDLPKIKPDLCSPQREQPTEKPEQELPTDLSSNKRRTMTPPEPPQPAAPAPPGIFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGICLPEQSEYERHVVAHFLITSSEFNCSASCGKSFAKSDELQQHLNSEHVLTLLKCALCSELCESRMAMQLHLACAHSQETKLLRCSACMELFRNDTDFHVHVKTRHQLGNPSAGVGPPGAAPGPANPLQCMFCRAVCASELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGLKDKEPSSPNMGSLYVNALLPPLAAAAAAAAAATNNNSNLHIDYNVAFKGLFGAGAAPASAQPGSQKFYSPLQVDTSGLKPQQSPHPALMYGLSQRYLMEMYAAKATSPAASAPEVPVQASQVNATASSAGSSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNFKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLTEHGGDGNLPMACICCRQTLHSEFELSLHAKFHTKSPSGSGSLQEPVCALCLEPLPEAGETAKLCEKCCRKHNLNGKRSKDPPPLVLPAPSSNAYLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPAGLLTHIAEHGARPYDCNLCPEKFYFRAELEHHQRAHELRPPPPLPGRNSSITQQPKQEPLHGASSTASSPHLAMSPSHVKQELYESEAASPSPSSSDPPAQEDEEYIEVEQVPHETRSDELLSAAHTDRSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00538445;
90% Identity
iTF_01570418;
80% Identity
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