Basic Information

Insect: Hirtodrosophila trivittata
Gene Symbol: ZNF574
Assembly: GCA_035045065.1
Location: JAWNNK010001311.1:10044548-10046782[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.034 2.8 8.8 0.4 2 23 332 354 331 354 0.96

2 10 1.5 1.3e+02 3.6 0.2 6 23 364 381 364 381 0.97

3 10 1.4e-05 0.0012 19.5 0.9 1 23 387 409 387 409 0.98

4 10 0.00022 0.018 15.7 0.5 1 21 422 442 422 445 0.87

5 10 8.3e-05 0.007 17.1 0.6 1 23 453 476 453 476 0.97

6 10 2.6e-05 0.0022 18.6 1.0 3 23 484 505 482 505 0.92

7 10 0.0028 0.23 12.3 0.4 2 23 517 539 516 539 0.97

8 10 3.8e-05 0.0032 18.1 3.6 1 23 546 569 546 569 0.93

9 10 2.4e-06 0.0002 21.9 1.2 1 23 575 597 575 597 0.98

10 10 5.8e-05 0.0049 17.5 1.4 1 23 603 626 603 626 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.034	2.8	8.8	0.4	2	23	332	354	331	354	0.96
2	10	1.5	1.3e+02	3.6	0.2	6	23	364	381	364	381	0.97
3	10	1.4e-05	0.0012	19.5	0.9	1	23	387	409	387	409	0.98
4	10	0.00022	0.018	15.7	0.5	1	21	422	442	422	445	0.87
5	10	8.3e-05	0.007	17.1	0.6	1	23	453	476	453	476	0.97
6	10	2.6e-05	0.0022	18.6	1.0	3	23	484	505	482	505	0.92
7	10	0.0028	0.23	12.3	0.4	2	23	517	539	516	539	0.97
8	10	3.8e-05	0.0032	18.1	3.6	1	23	546	569	546	569	0.93
9	10	2.4e-06	0.0002	21.9	1.2	1	23	575	597	575	597	0.98
10	10	5.8e-05	0.0049	17.5	1.4	1	23	603	626	603	626	0.97

Sequence Information

Coding Sequence: ATGGCATCCTGTGTGCTTTGCCTGGGGTGCTGTAAGATCGGAGAATCCTATAAAGTATTTTCCGAGACAGGTTTTCGGCTCAACATttgcaaaacaataaacaaacactttTGGCTAGAGtTGAACAGCGCAGGGGGAAAACGTGAGGAGATTTGCTATCAGTGCTGGGAATGCGTTAGCAGTTTCAATGAATTTTACCAACGCGTCTACAGTGTACACCAGGAACGACGTTGCGATGTCAAAGATATACCCATCGAGTTCTGTGGTGAGACGGTGGCAGCCAATCCACTTGCATTTATAGCTGAAATGGATGCCTTGGCCGAGGATTTTTTCGCAACTGACGATGTTAAAGTGGAAGTAAACGAACTGGAGCCGCTGCCAAAGTTGGAAATGCTCGACGAGCCAGTGTTAGGAGAAACAAGCAGTGCTACTAAACGGGCTAGTACCGACTATCCCGTTGCTCCCAAACGCCGCATTAAAAACGAGCAAATAACGGTGGCCAGTGACTCGGATGGCGATATTCCGCTGGCTGAGTTCCTGGACTTAAAAACCCCTGAAAAACCAATTGCAACGAATGATGATAAGCAAACGTCAGTCAAGGGCCGACCACTGCGCAGAAGCTCTCGACGTGGGCAAAGGGCGAAAACGCCTCCAGAATCTCTGAACAGTTTCAAAAAGGAGTTTTTGACTGATGATGAGCAGGATAATGGTGACGACCTGGACTTTGTGGCGGCGGAAGCAGTGCTGGGCACTGATGACAGCGCCAGTTCTAGTGAGAGCAGCGACAGTGACTCTGGCGAAAGTTTGCCCGATATTGAGCCAGAGGAGCGCTATGCAGAGATACCCAAACGGGTTGTAGTCAAGCCCAAAAAGTATCGCAAACGTCCTAAGCCGTTGGTGCCGCCGGTCCGCATGAGTCGCGACGAGATCGAGAAACGAAAAGCGCAACAAAATGAATTCGATGAGATTATATTTGACTTTTTCAAGAAACTTCCATGTCACGTGTGTAATTTGCTAGTGCCCAATTTCGGAGATATGCGACGCCATCTACGTATGTCCCACAATATTGAAAGTGGATTTATATCCTGCTGCGGTCGCAAGTTTCACATACGCAAAGCCCTAGCCGAACATGTGCTGGTCCACAAAAATCCTGAGCATTTTATGTGCACCCAATGCGGCCGCGTTTTTCAGGACTCCAAAACCCTTGAAACGCACGAACAAACTCACACAAATCCTCAGTCGGATACAAAAGATAAACGGACTTACCAGTGTGACAAGTGTCCCAAGGTTTTTACCACAAAGGCTGCTGTCGAGTATCACAATGTATCCAAGCATGTGCCCAAGTCTGACTTTAAGTACTCCTGCCCGGAGTGCAACAAGAAGGTGCCCACAGAAAGAAAGCTTAAGGAACACCTGCGCTATATGCACGATCCGGAAACGGCCATCATTTGCGACAAGTGCGGAAAAACGTTGCGCTCCCAGGCGAATCTTAAGAAGCATCACGAACTAGAACATTCCGATAAGCCACGCCCTAAGCCCGATCCAGTTCAATGTGAAATATGCGGCACCTGGCTTCGCCATTTATCCGGCCTCAAGCAGCACATGAGCACCGTGCATGAGCCACCCGGAGGCGAGCATCGTTGCCCCATCTGCGACAAGACTTCCACAAACTCGCGCGCACTCAAGCGACATATATACCACAATCATCAGTGCGAGCGAAAGTTCCGCTGTACCATGTGTGAAAAGGCCTTCAAGAGGCCACAGGATTTGAGAGAACATACATCCACGCACACGGGTGAGGTGTTGTACACCTGCCCCAACTGCCCACAGACGTTCTTCTCCAATGCCAACATGTACAAGCATCGACAGCGACTGCATCGAGCCGAGTGGGAGGCGGATCGCAAAAAACCGCTTCCACCCAACATAATGCAACAAGCTGTGGGCGCCACGACGGCAATGAAGAAACGTCAGGCAACGAATGCGGGCACAACGTTGTTCACGCAAGCCACTGACTCTGCTGGGGAAGTCCAGAAACAGGAGTCGCAGATACAATAG
Protein Sequence: MASCVLCLGCCKIGESYKVFSETGFRLNICKTINKHFWLELNSAGGKREEICYQCWECVSSFNEFYQRVYSVHQERRCDVKDIPIEFCGETVAANPLAFIAEMDALAEDFFATDDVKVEVNELEPLPKLEMLDEPVLGETSSATKRASTDYPVAPKRRIKNEQITVASDSDGDIPLAEFLDLKTPEKPIATNDDKQTSVKGRPLRRSSRRGQRAKTPPESLNSFKKEFLTDDEQDNGDDLDFVAAEAVLGTDDSASSSESSDSDSGESLPDIEPEERYAEIPKRVVVKPKKYRKRPKPLVPPVRMSRDEIEKRKAQQNEFDEIIFDFFKKLPCHVCNLLVPNFGDMRRHLRMSHNIESGFISCCGRKFHIRKALAEHVLVHKNPEHFMCTQCGRVFQDSKTLETHEQTHTNPQSDTKDKRTYQCDKCPKVFTTKAAVEYHNVSKHVPKSDFKYSCPECNKKVPTERKLKEHLRYMHDPETAIICDKCGKTLRSQANLKKHHELEHSDKPRPKPDPVQCEICGTWLRHLSGLKQHMSTVHEPPGGEHRCPICDKTSTNSRALKRHIYHNHQCERKFRCTMCEKAFKRPQDLREHTSTHTGEVLYTCPNCPQTFFSNANMYKHRQRLHRAEWEADRKKPLPPNIMQQAVGATTAMKKRQATNAGTTLFTQATDSAGEVQKQESQIQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00508523;
90% Identity: iTF_01570407;
80% Identity: -