Basic Information

Insect: Hirtodrosophila trivittata
Gene Symbol: Znf516
Assembly: GCA_035045065.1
Location: JAWNNK010000855.1:10963250-10964936[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00064 0.054 14.3 0.3 1 21 214 234 214 237 0.90

2 8 1.6e-06 0.00013 22.5 1.3 2 23 259 281 258 281 0.93

3 8 0.00021 0.018 15.8 0.2 2 23 308 328 308 328 0.97

4 8 1.2e-05 0.001 19.7 2.5 1 23 334 356 334 356 0.98

5 8 8.5e-06 0.00071 20.2 0.9 2 23 363 384 362 384 0.97

6 8 4.2e-08 3.5e-06 27.4 0.8 1 23 390 412 390 412 0.98

7 8 0.47 40 5.2 0.8 1 21 418 438 418 442 0.87

8 8 8.3e-05 0.0069 17.1 0.3 1 23 490 514 490 514 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00064	0.054	14.3	0.3	1	21	214	234	214	237	0.90
2	8	1.6e-06	0.00013	22.5	1.3	2	23	259	281	258	281	0.93
3	8	0.00021	0.018	15.8	0.2	2	23	308	328	308	328	0.97
4	8	1.2e-05	0.001	19.7	2.5	1	23	334	356	334	356	0.98
5	8	8.5e-06	0.00071	20.2	0.9	2	23	363	384	362	384	0.97
6	8	4.2e-08	3.5e-06	27.4	0.8	1	23	390	412	390	412	0.98
7	8	0.47	40	5.2	0.8	1	21	418	438	418	442	0.87
8	8	8.3e-05	0.0069	17.1	0.3	1	23	490	514	490	514	0.91

Sequence Information

Coding Sequence: atgaacAGGATCAGAACCGTAAGCGTGTCCGAGATCGAGATTCCAGTGCAAGTCAAAGACAACATTTCTGTGGACGCGCAGACTTGTCGCGTTTGTCTGGAATCTCACGAAACCACACTCTGCCTTCTGGATGAAATTGAGTACAACGATTTGAATGTCGAACTATGGCAGTTGCTGGAGAGCGTAACTAATGTAAAGTGCACCTGGAATGAACCGAATCTACCCACACAGCTCTGTGAGAGGTGCACACGGCGCTTGATTAGTGCTTATGAGTTTATACGCGAAGTTGAAAGATCTCAGCAGACCCTCCAGGAATTGTGCAACAGTCAAGAGCTAGATCAGTCTATTGGATCCATCGAAAATGTGAAAGAGGTTGAGAAAGAAGAAGTTGAGTGGATACCGGACGACGAAATCATCCAGTTGGATGAATGTGAATCGGTCATTGAGCTTCAAGACGACCCGCCCGGAAACGACAACGAACTAGATGTGAACACACTAACTATTGACGCAGAATCCAGCGAACTGGCTGGCGAGTTTGTGCAAGACGAGTCTGATGcagaaataaattgtaatgATAATCAAGAAGAAGAGCGTCCCTCGCAATTGGGCATGCGACTTGGTCATTCCCAAAGCTATATGTTCAAATGTGACAGTTGTCCACGCATTTTTGCTAAAAACAAATCGTTGGCACGTCATTTTGCAGCAGCTCACAGTCAAGCAGCCGACGTGGCGGCTCAGGAGCTGGCGAAAGAGCatagcagcagcggcgcacTTATCTGTGAGCACTGTCCACGTATCTTTAAGCGTCAGGATACACTGCGCCGACATATGCTCGCATTTCACCCCGAAGTGGTCGCAGCTACTGCCGATTCAGAGGATGCCACAAAAACTGCGCCAACAAAACGTGCAGTTAAACGGCGCGAGTGCCCCCACTGTGGAGTTAGCTTTCCCGTATCAAGTCTGACCATACATATACGCCGTCACACCGGAGAGAATCCCTATAAGTGCGATCAATGTGACAAAGCATTTCCACGCAGTCAGGATCTCAGTTTACACAAGCGCCACCACACTGGCGAGCGTCCCAGTGAATGCAAGATATGTGCCAAGAAGTTCATTTCGCAAAACAAACTGGCGCGGCATATGCGCCTGCACACGGGTCAGCGTCCTTACGCCTGTGACAAGTGCGACAAGAGTTTTGTCCAGTCCAACGATCTAAAGATTCATATGCGCCGACACACGGGCGAGCGCCCCTACATCTGTGGTGTTTGTGCCAAGAGCTTCGTTTGTGGCTCCCTGCTAAATATTCATCGCAACCAGAAACAGCACTTTGAGGCCGTCGGGGAAGGTAATGAAGACGCCGATCTCGATCCCTACGAAAATAGTCGCGTGAACAAGAGACGAGCTGAAGACATTGAACGCATGCGACTGCAACGTGAGAGTGAGGCGCTCCTAGTCGGGCCGCACCCGTACAACTGTGGTGTGTGCGGAGAAACCTTTAAGAGTGGATCCCTGCTTACTATACACCGCAACAAGATGTCTCATTATGAAGTCAGCAAAGTGGACTATGGCGATCCTTACgagcaaaaatataaacaacaacagcaacaccctAGTACGGATTAG
Protein Sequence: MNRIRTVSVSEIEIPVQVKDNISVDAQTCRVCLESHETTLCLLDEIEYNDLNVELWQLLESVTNVKCTWNEPNLPTQLCERCTRRLISAYEFIREVERSQQTLQELCNSQELDQSIGSIENVKEVEKEEVEWIPDDEIIQLDECESVIELQDDPPGNDNELDVNTLTIDAESSELAGEFVQDESDAEINCNDNQEEERPSQLGMRLGHSQSYMFKCDSCPRIFAKNKSLARHFAAAHSQAADVAAQELAKEHSSSGALICEHCPRIFKRQDTLRRHMLAFHPEVVAATADSEDATKTAPTKRAVKRRECPHCGVSFPVSSLTIHIRRHTGENPYKCDQCDKAFPRSQDLSLHKRHHTGERPSECKICAKKFISQNKLARHMRLHTGQRPYACDKCDKSFVQSNDLKIHMRRHTGERPYICGVCAKSFVCGSLLNIHRNQKQHFEAVGEGNEDADLDPYENSRVNKRRAEDIERMRLQRESEALLVGPHPYNCGVCGETFKSGSLLTIHRNKMSHYEVSKVDYGDPYEQKYKQQQQHPSTD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01570397;
90% Identity: -
80% Identity: -