Basic Information

Insect: Hirtodrosophila histrioides
Gene Symbol: -
Assembly: GCA_037075165.1
Location: JBAMCL010000646.1:8704315-8709687[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.00054 0.036 14.8 0.1 1 23 171 194 171 194 0.96

2 13 0.0019 0.12 13.1 2.9 2 23 243 265 239 265 0.89

3 13 0.015 1 10.2 0.5 1 23 382 405 382 405 0.93

4 13 0.97 64 4.5 6.1 2 23 454 475 453 476 0.95

5 13 0.0042 0.28 11.9 0.5 1 23 547 570 547 570 0.88

6 13 2.6 1.7e+02 3.2 0.1 2 14 589 601 588 613 0.85

7 13 0.0009 0.06 14.1 3.3 2 23 621 643 621 643 0.96

8 13 0.00073 0.049 14.3 0.1 1 23 750 773 750 773 0.95

9 13 0.00054 0.036 14.7 0.1 1 23 840 863 840 863 0.93

10 13 0.0015 0.1 13.4 2.2 2 23 913 935 912 935 0.97

11 13 0.0024 0.16 12.7 2.0 1 23 1024 1047 1024 1047 0.92

12 13 0.28 19 6.2 2.4 1 21 1099 1119 1099 1120 0.95

13 13 0.018 1.2 9.9 0.1 2 14 1169 1181 1168 1193 0.83

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.00054	0.036	14.8	0.1	1	23	171	194	171	194	0.96
2	13	0.0019	0.12	13.1	2.9	2	23	243	265	239	265	0.89
3	13	0.015	1	10.2	0.5	1	23	382	405	382	405	0.93
4	13	0.97	64	4.5	6.1	2	23	454	475	453	476	0.95
5	13	0.0042	0.28	11.9	0.5	1	23	547	570	547	570	0.88
6	13	2.6	1.7e+02	3.2	0.1	2	14	589	601	588	613	0.85
7	13	0.0009	0.06	14.1	3.3	2	23	621	643	621	643	0.96
8	13	0.00073	0.049	14.3	0.1	1	23	750	773	750	773	0.95
9	13	0.00054	0.036	14.7	0.1	1	23	840	863	840	863	0.93
10	13	0.0015	0.1	13.4	2.2	2	23	913	935	912	935	0.97
11	13	0.0024	0.16	12.7	2.0	1	23	1024	1047	1024	1047	0.92
12	13	0.28	19	6.2	2.4	1	21	1099	1119	1099	1120	0.95
13	13	0.018	1.2	9.9	0.1	2	14	1169	1181	1168	1193	0.83

Sequence Information

Coding Sequence: ATGGAAGGTATGGATCTGTGGACGTCCATGTTTTCGGCTGACTTTGAGGAGGGGGACGCTGAGGCAGACTATCATAATAATGGCAACAATCTGCATGTCGACGAGTTTATCGCCGAGGAAGAAGAAGAGGAGCAGGAGGCTATTTTGGATGAGGCGGCTGATGTTGGGGAGGGGGAGTTTGACAGCAGACGCCACAAGCAAAAAGGACCCGAGCCAGATGATGATGccatatttgattttgaactAGAGCCCATTGTTAGCATTGCCGAGCCGGAACTCGAAGCGCCGACCCGTAGAAGTGTTCCATTGGCACCACCAATGCCAACTGGCCCACCCATGCGGCCTACACATCGTCAGTCGCTTCCCTCAACGCTACAAGGTCGCGGGGCGGGGCCAGCACCGAGTGTGGGTGTAGTTGTGGGAGGTGCTCCACCAATGCGACCTACAACATCACAGATCAATGCCACCGATGAGAATGGTGTGCCCATTAATTATGAACTGGGTGTCATTTATATATGCCCCGCCTGCGGCGCCGAGTATCGCCAGCAGGACATGTGGAAACGTCACATGAACCAAATGCATCAGTATAATACGCGACGTGGCCTCAATTTTGTGGCCATCGATAAGCTATATCATCGCTGCCTGGAGTGCAACAAGCGCATTGCCATGCACAGTCGCGAGAATCTGCTGAAGCATAAGTTTACCCATTTGCCATATCGTTGCACCAAGTGCTACATTTGCAAGCGAGAGTACAAGTACAGGCAGGACCTGATGGTGCATTTGCGCATGGTGCACTGTGACGAGGTGGTGGCCATGATGCGCGCCGGCGATGCCACGGCCGGCCGTAAGACACGCGTGCGTGAGCCCCGCAccgagcagcagcatcatGGGGGCTCCTATGTCCGTCTAATGCCAGACGATGACGATGCCATTGAGGTCAAGAATGAGCTAATGGAGCCGGAAGCTGCTgcaccagctgctgctgctgctgttgctgatgagCCCAGCTTCGGTTTGGATGATGAACAGAGTCACAGCACAGCGACCAGGAAGAAGCGCGGTAATGCAACTGCAAGCAATGCCAATGGCACTgccggcggcggcagcggcagcgctgtCGATATGTGCGAGGATTACATACACTACATGTGCCCGGACTGCGGCGCCGACTGTGACACGCACGCCCAGTGGAACCAACACATTGAGTTTGTCCATGATTATGTCAGCCGACGCGGACTCAACTTTCGTTGCGTGGATATGCAAATGCAGTGCCTGGAGTGCAAGCAGGTGGTGATCCCAAATACGATCAAGACGCTGCGCGCTCACAAGTTCAGTCACTTGCCACAGCCAGAATGGATGCGCTGCAAGCTGTGCTACAGGGACTACACGGAGCACCATGATCTGGTTACACATTTGCTCAAAcaccatcaactggagaccttaATGCCCGACTTGGAGGAGGAGCCAACGCCAGGGGGCGGTGATGATGTCGAGGATAACACTGGCAATGACAATGGCAACGgggatggcgatggcgatccCGATGGCTACGATGATGAATCATTGTCACATTGGGATGATGCACCACGTCGTGGCGGTCGCATTGGCAGCGATGACATGTACGAGCCGCACATTGATTATCTGTGCCCGCAGTGCGGCAGAGAATTCATCGAGAAGAAGCACTGGCGCACGCATGTGGTGCAGGTGCACGGCATGAACGATCTGGCCAAGCTGAACTTTGAGGTGATCAACGATCGTCAGCTGAAGTGCACCGAATGTGACAAGATCATAACCAATGCGTATGGCATACAGAATGCCCAACAGCATCGGATAACGCATCTGCCATACAAGGCGTATGCGCGCTGTCGCAAATGCCACAAATCGTACACGGATCGGAAGGGCTTGGTCAAGCACTTGGCCACCTATCATCGTGTGGGCTACGAGCCGCGCAAAGTTGCTGGCGGAACGGGCGCCGGCTTAGCCGGTACTGCAGGCGGGCAGGCAGCCAAGACGCAGCCGCCGCGGAAACAAATTGTTACTGTGGCCAATGAAACCTAtgagattatttatttagatgaGGAGCAATCACCGCCCAGCAatagtaacagcaacaacaacaacgaagagAATGATTTTGGGGAGCTAATGCAAgcggatgatgatgattatgccATTGGCAGCACTATAAACAGCTCTAGTGGCAGCAGTCGTCAATTgacgccagctgctgcagccaaTCCCAATCGCTACAAATGCGTTGACTGTGGCTCCTTGTTTCCCACACAGGCCTCACTCAAGACGCACATTAGCGAGGAGCATGACTTTATGGATACACAATACAGTGCCAAAACGTTTGACAATGCAGAGCCGACGGATGAGGcagcttcagctacagctacGGCTACGGCTACAGCTTCTGCTTCCGCTTCAGCGGCATCAACGTCGCCACCCACAAGTAGCGGTAGCAAAAAAGCACTTAACAGCACTGGTGGCTCCACTATTgagcaaaattatatatttttatgcccCTCGTGCGGTGAAGCATACAGAACGCAGTTCGAATGGCGCCGCCATATCAACGAGGCGCACAATTTTGATAAGCGTCAGTATTTGAATATGCGGCAGCTGGACAAGTATCGTTATCAGTGCACACAGTGCAAGGACATTGTGTGCAATTCAAAGCTAAAAGGACTGCAGGATCACCACTTTCGCCATCTGCCCTATCGATTGTATCTGAAGTGTTTGGTTTGTGGCACCTGCTACAATCACAAGCCGAACATTGCCGCACATTTGCGAACGCGCCATAATATCTTCGAACGTGAGACGCCCTGGCGTGAGATGCAGCCAAAGCCACAATATGGCTATGTATTGACTAAGGACAAGGAGAAGGATAAGGAAATGCGTGCAATTTCCTCAACTTCGTCATCGCCGACGCCAACTTCCAGCAGCAGTGCTCTGGGGCGCTCGCTGAAGCCACAACCGGGCGTGCTGCCCAGCCGACCCGCTGGTCTCAATACGCTGGAAGATAGCATTTCGTATCATAATGCAGTGGATCTGGACTTCATCACATACTACTGTCCCAAGTGCAACAAGAACTTTGATTCGCACGCCTTCTGGCGTAAACACATCGTGGAGCAGCATAACTTCAACTGTCGGCAGGGCTTAAATTTTCGCCAGATCGACAACCATCACTATTTATGCCTGGAGTGCTATAAGCGGGTGACAGTTACACACACCAAGGGGGCCATTGGGCAGCTGCAGTCGCACAAGTTCCGTCATTTGCCATATCGCTCCTTCAAGTGCTTGAGCTGCAAGAATGAATTTGTGCGCAAGCAAATGttctttaaacatttaaatcgCGACACAAATCGCTGTGACAGCCAGCCGCTTAGTATCCAGGATAATGATGATAACGATGACGTTACGGTGCTGCcaggcagtggcagtggcgcTGAAAGTTCAGTACTGCCCGGTGGACAACTTGATCCTGCGACTTACCGCCTGATGTGTCCGCAATGTGGCGAAAGCTTTACCACCAGCAGTAAGGCGCTCTGGCGGGAGCATATCAACATTTACCATGGGCTGGGCAAGCGTGAGCTGCTTAATGTACGTAAACTGGGCGAGGATCTCTATGGCTGCACCGACTGTGACGAGCAGCTGCAGACGAAGAAGCTGCGTGTTCTGCAGCAGCATCGCTTCAAGCATTTGCCCTATGCCGCGTACATACGCTGCCAATTGTGCGAAAATCTGATGGATGGACTGGAGCACAGttctgctgcagctggacTGCACAGCATGCGCGAACTACAGCAACATATACGCGACCAGCATCCGGATTTGGCCGAGAAcgaacaacaaatgaaattgttgctgGACGATGAGGACAGTCAGCCGGCAAACAATGGTCCGTATATGCCGATGCCTCCGCATTTGTTGGACGACGATGTCGATGACATTGATTTTGAGGACCAGTATCTGCTAGGCTAG
Protein Sequence: MEGMDLWTSMFSADFEEGDAEADYHNNGNNLHVDEFIAEEEEEEQEAILDEAADVGEGEFDSRRHKQKGPEPDDDAIFDFELEPIVSIAEPELEAPTRRSVPLAPPMPTGPPMRPTHRQSLPSTLQGRGAGPAPSVGVVVGGAPPMRPTTSQINATDENGVPINYELGVIYICPACGAEYRQQDMWKRHMNQMHQYNTRRGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMRAGDATAGRKTRVREPRTEQQHHGGSYVRLMPDDDDAIEVKNELMEPEAAAPAAAAAVADEPSFGLDDEQSHSTATRKKRGNATASNANGTAGGGSGSAVDMCEDYIHYMCPDCGADCDTHAQWNQHIEFVHDYVSRRGLNFRCVDMQMQCLECKQVVIPNTIKTLRAHKFSHLPQPEWMRCKLCYRDYTEHHDLVTHLLKHHQLETLMPDLEEEPTPGGGDDVEDNTGNDNGNGDGDGDPDGYDDESLSHWDDAPRRGGRIGSDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECDKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHRVGYEPRKVAGGTGAGLAGTAGGQAAKTQPPRKQIVTVANETYEIIYLDEEQSPPSNSNSNNNNEENDFGELMQADDDDYAIGSTINSSSGSSRQLTPAAAANPNRYKCVDCGSLFPTQASLKTHISEEHDFMDTQYSAKTFDNAEPTDEAASATATATATASASASAASTSPPTSSGSKKALNSTGGSTIEQNYIFLCPSCGEAYRTQFEWRRHINEAHNFDKRQYLNMRQLDKYRYQCTQCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIFERETPWREMQPKPQYGYVLTKDKEKDKEMRAISSTSSSPTPTSSSSALGRSLKPQPGVLPSRPAGLNTLEDSISYHNAVDLDFITYYCPKCNKNFDSHAFWRKHIVEQHNFNCRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLSCKNEFVRKQMFFKHLNRDTNRCDSQPLSIQDNDDNDDVTVLPGSGSGAESSVLPGGQLDPATYRLMCPQCGESFTTSSKALWREHINIYHGLGKRELLNVRKLGEDLYGCTDCDEQLQTKKLRVLQQHRFKHLPYAAYIRCQLCENLMDGLEHSSAAAGLHSMRELQQHIRDQHPDLAENEQQMKLLLDDEDSQPANNGPYMPMPPHLLDDDVDDIDFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00803927;
90% Identity: -
80% Identity: -