Hhis010611.1
Basic Information
- Insect
- Hirtodrosophila histrioides
- Gene Symbol
- -
- Assembly
- GCA_037075165.1
- Location
- JBAMCL010000474.1:1818331-1854963[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 7 0.00024 0.016 15.9 4.6 1 23 424 446 424 446 0.98 2 7 2.5e-05 0.0017 18.9 5.2 1 23 452 474 452 474 0.98 3 7 4.6e-07 3e-05 24.4 0.9 1 23 480 504 480 504 0.99 4 7 2.9e-05 0.002 18.7 0.7 1 21 516 536 516 537 0.93 5 7 0.61 41 5.1 1.2 2 23 560 582 559 582 0.94 6 7 0.0005 0.033 14.9 2.2 1 20 651 670 651 673 0.94 7 7 0.023 1.6 9.6 0.2 2 20 687 705 686 707 0.94
Sequence Information
- Coding Sequence
- ATGAACGAAGCCCAACAGCAACCGGAACCGGAACCCGAACTGGAAATTCAGGGGCTCCAGCAGATCTCGCACAACAAGATTCCATTTCGTATGTTTAAAATGGATGCGGCTGATTTTTGGCAACAGGCCCGAGCACCCTTCGCACTGCACACTGCCGCGACGGCGCTGCACCAGcatcagcaccagcaccagcacccgcaacagcaacagcacccGCAACATCACCCGCGCCCGCACCCATTATCCAATCAACAGGAGCAACATGCCAACCCTCCTAAAAACAATAACCACCTGCCATTGAACAGCAAATTGGAGCCAAACCAGGTGCAACACCAACAGccgcatcagcaacaacagcaacaacagcaacaacagcaacaccagcaacaacagcagcaaccacagcaacaacaacaacagcagcagcagcaacaacaacatcagcagcaacaacagctccTTCAGCACGTCGAGCACTGCTATGGCAATGAATCGTTTGGAGCACAGCCGTCAGTGACAACAGCACCAACGTCCACGCAGCTGAGCAACCACCATTTGTTGTTTAATGCTGCTGCCgcggcagccgcagccgcgCACCTTAAATCAACGGCCCTGAATAGCCACAGTCAGAACACTatcagcagcaccagcagtgCAACCTCCGCGGATCAGTCGGCGGACAACCCGCAGCCACTACCACTCCCTATCTCAACATTAAGCAGCCACAACCCCAACAGCTCTGCCAGCCTAGCAGTAAAGCTCAAGCAGGAGcatggccaacagcagcagcagcagcacgtcGATGATCCCCGCCAGCAACAGCCGGAGCAGACTTACGGGGGAGCATTTTTCGGGGGAACCGGAGCCACCGAGCAGCAATCGCACcttcagcagcaacaacagcagcagcccccTCATCAGGCCAACAGCCCGACACTGACAATGCTCAACAAGTCAATGTCCCAGGGTCAGCAGTCCCCACAACACTCCATTACACCATCGGGCGGCAGCTCTACGCCCGATATCAAGTACAACAACGAAAAGCTGGCCAACGAGATCCAGCTTCAGCTCTCCAGGTCGAGCAGCGCAGCCGCGATCAGTGAACGCACCCTTGAAGAATGTTGGTCAACCCTGCAACGACTTTTCATGCACAAGAGCGCCATGCAGCAGATCCAACAGCAGATTCCTCGAGTCGGCCTGGGGGCGCACGGCGTGGCCAGCACTGCTAGCATGGGCGGCGGAACGACGCCCGGGGCAGAAACAAAGCCCCACCAGTGCCAGCAGTGCATGAAGAGCTTTTCTAGCAACCATCAGCTCGTGCAGCATATTCGCGTCCATACAGGCGAGAAGCCGTACAAATGCTCCTACTGTGATCGTAGATTTAAGCAGCTATCCCACGTGCAGCAGCACACGCGCCTTCATACCGGTGAGCGCCCTTACAAGTGTCACTTGCCAGACTGCGGACGAGCTTTCATACAGCTCTCCAACCTGCAGCAGCACCTGCGAAACCATGATGCCCAGGTGGAGCGCGCTAAGAATCGTCCTTTCCATTGCAATATTTGTGGAAAGGGATTTGCAACCGAGTCTAGCTTGCGTACGCACACATCCAAGGAGCTACAGCTGCATCTTGGTGTCTTGCAGCAGCATGCGGCTCTGATCGGTGGTCCCAATGCGACGTCATGCCCGGTATGCCACAAGCTTTTCCTTGGCACTGAGGCACTAATGGACCACATGAAGCATGTTCACAAAGAAAaatcgccgccgccgctgccgagCGAGCCGCCTGGTCAATTCGGTGATGGAGTCCATAGTGGTGGTGGCAACGGTGGTAACGGTGGGGCCGGTTCCCTCGCAGCACAATGCGCCTCCGAACTAGGATGTGCGCAACCGTCGACGACCAGCGGATCCAGCTTAAATGATAGCTACCTCGGCAAGCGGAGAACAGCCAACCATCCCTGTCCTGTGTGCGGCAAGCACTACGTTAACGAGGGTTCTCTTCGCAAGCATCTAGCCTGTCACGCAGAAACCTCACAACTGACAAGCAGCCTGCGGATGTGGCCCTGTTCCGTTTGCCAAGCAGTCTTCACGCACGAGAACGGTCTTCTCACCCACATGGATCATATGCGTATGGATCCTAAACATCAGTTTGCGGCACAATATGTTTTGTCCCGAGCAGCGGCAGAGCAAAGAGAGCGCGAGTCCCTATTGGCGACGCTAGCAGCTTCATCAGCAAGCGGCGGAGTGAGAGAGACTTCAAGTATGCTGGACGTAGGCGGGGTAACCGGGGGAGGCTCCAACTCATTATGTCCCTCGCCATCAGCAAATTCGGAGTGTTCATCAAATGGACGGCTGTCTTCTTCATCCACCTCTGATCAGGATCACGATCAAGATCAAGGCTTGagcgaaaatgaaaatagcagccacaataacaacattaacaacgtaaacaacaataacaatagcatgaacaataataataataataactgtaGCTctgccaaaattaatttcaacgAGCTCCGACTGCCCAGTTCCAGCCAGTACAGTATGGATGCCGAACTCCATGCCAATCGCATGTCCCTAATGGCGGCAGCATCAGCTGCCGCAGCGGCTGTGGCAGCCTCGGCTGGTTCCCGGTCACAGGATGGGGCTATTGACGCAGTCACTGCCGGTCCAGGCAGTGCAGTTGTCCAAGCTGCAGTTGTCAACTTGGCTGCCGCCATGCGCATGAACAATCCCGCCAATCCGCACCAGCAACAGCATGGCGAGCACCAGCTGCACCAGCAAAAtcatcaccagcagcagcaacaggcacaGCATCAGCACCAGCATCATCAACAGCAATTATCCCATCTGCCGCTGCTATCCCCCCTTAGCAGCCAACAGACGCATCCTGGTAGCAGCAACACACGGCGGTCTCCAACCCTAAACGTTCCTAGCCGCCAAATGCAAGCCGACACATCGTCCGTCATGATGAGCATGATGCGCGGTACCTTAGATCGCTCCTTGGATCCAGGTCTAAGCGGCATGCATCCAATGGAGGCGCAGCATCATCAACCCCACCAAGCCTCGAATTATTCGCAACACGCAGTGACACCAAGTTCGCAACAGCCGCCATCTCAtcctcaacacacacacacacaccatccGGAGACAGCCCTGCGCATGCACCAGCAGGCGGAAGCCATACTGCGCTCCCACACGGAAGCGGCATTTCGTCTGGCTGCCTCGGTGGCAGCCACGAATGGTCCCAACGCTAATGTCAACTCGATCCCCACCGGTACGGGCAGCGGTACCGCAAGCCTCGGAATTAAAAGCGAATCAACGGGACAGCAACATCGACAAATCAATGGCAATGAACTTCATGCATCGCCACATCGCTTCCAATCGAGCGCGAACCAAACACAGCACCCGCAAACTCAATCGCAACAGGATCAATCAGCTACACACAACTCATGA
- Protein Sequence
- MNEAQQQPEPEPELEIQGLQQISHNKIPFRMFKMDAADFWQQARAPFALHTAATALHQHQHQHQHPQQQQHPQHHPRPHPLSNQQEQHANPPKNNNHLPLNSKLEPNQVQHQQPHQQQQQQQQQQQHQQQQQQPQQQQQQQQQQQQHQQQQQLLQHVEHCYGNESFGAQPSVTTAPTSTQLSNHHLLFNAAAAAAAAAHLKSTALNSHSQNTISSTSSATSADQSADNPQPLPLPISTLSSHNPNSSASLAVKLKQEHGQQQQQQHVDDPRQQQPEQTYGGAFFGGTGATEQQSHLQQQQQQQPPHQANSPTLTMLNKSMSQGQQSPQHSITPSGGSSTPDIKYNNEKLANEIQLQLSRSSSAAAISERTLEECWSTLQRLFMHKSAMQQIQQQIPRVGLGAHGVASTASMGGGTTPGAETKPHQCQQCMKSFSSNHQLVQHIRVHTGEKPYKCSYCDRRFKQLSHVQQHTRLHTGERPYKCHLPDCGRAFIQLSNLQQHLRNHDAQVERAKNRPFHCNICGKGFATESSLRTHTSKELQLHLGVLQQHAALIGGPNATSCPVCHKLFLGTEALMDHMKHVHKEKSPPPLPSEPPGQFGDGVHSGGGNGGNGGAGSLAAQCASELGCAQPSTTSGSSLNDSYLGKRRTANHPCPVCGKHYVNEGSLRKHLACHAETSQLTSSLRMWPCSVCQAVFTHENGLLTHMDHMRMDPKHQFAAQYVLSRAAAEQRERESLLATLAASSASGGVRETSSMLDVGGVTGGGSNSLCPSPSANSECSSNGRLSSSSTSDQDHDQDQGLSENENSSHNNNINNVNNNNNSMNNNNNNNCSSAKINFNELRLPSSSQYSMDAELHANRMSLMAAASAAAAAVAASAGSRSQDGAIDAVTAGPGSAVVQAAVVNLAAAMRMNNPANPHQQQHGEHQLHQQNHHQQQQQAQHQHQHHQQQLSHLPLLSPLSSQQTHPGSSNTRRSPTLNVPSRQMQADTSSVMMSMMRGTLDRSLDPGLSGMHPMEAQHHQPHQASNYSQHAVTPSSQQPPSHPQHTHTHHPETALRMHQQAEAILRSHTEAAFRLAASVAATNGPNANVNSIPTGTGSGTASLGIKSESTGQQHRQINGNELHASPHRFQSSANQTQHPQTQSQQDQSATHNS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00617162;
- 90% Identity
- iTF_00803860;
- 80% Identity
- -