Basic Information

Insect: Hirtodrosophila histrioides
Gene Symbol: PRDM1
Assembly: GCA_037075165.1
Location: JBAMCL010000233.1:568019-572693[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 3.7e-05 0.0024 18.4 2.5 1 23 892 914 892 914 0.99

2 5 1.1e-05 0.00073 20.1 5.1 1 23 920 942 920 942 0.98

3 5 2.3e-06 0.00015 22.2 4.3 1 23 948 970 948 970 0.98

4 5 0.00077 0.051 14.3 2.4 1 23 976 998 976 998 0.97

5 5 0.00013 0.0087 16.7 0.1 1 22 1004 1025 1004 1025 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	3.7e-05	0.0024	18.4	2.5	1	23	892	914	892	914	0.99
2	5	1.1e-05	0.00073	20.1	5.1	1	23	920	942	920	942	0.98
3	5	2.3e-06	0.00015	22.2	4.3	1	23	948	970	948	970	0.98
4	5	0.00077	0.051	14.3	2.4	1	23	976	998	976	998	0.97
5	5	0.00013	0.0087	16.7	0.1	1	22	1004	1025	1004	1025	0.96

Sequence Information

Coding Sequence: atgcatggacttcatcatcatcatcaacagcagcagcagcaacagcagcagcagacgccgCAGCCGCAACAAGTGACGCAAACGGCAGCCACAATGAAAACGGCAGGCAatccacaacagcaacagcaacaacaacagcagcaacaacaacaaacacacatagccatacaacaacaacaacaacagcagcaacagcatacTCACCCACATCACCATCCACATCCACAAGCCCAACACAAtacacatccacatccacatcagCATCCACATCATCATGCGAAGCTGCTGCGACGCTcgcgcagccgcagtcgcagtccaACGCCTGACGGCACACAGGACTATGATGTGACGCGAATGCGGGAGGAGGACTTTGAGCGTTTGGCCGTATATCTGGTGCCTGACGTACAAGCGGAGCGTGGGCTGCCCAATCGAGCGGATAAGACATTACCGCGCAGTCTGACGCTCAAGTCCTCTATGGTCTACTCAACGCCAAATGTTAAGACTGAAGGAGTTTGGAGCAGCGGCGTCATACCGCGTGGCACACGCTTTGGCCCATTCGAAGGCATTCCAACCTCAAATTATCCAAATGATAAGAATAAGGCGCGCTATTTCTGGCGGGTGCAGGGAACACGCCACATAACCTACGGGAATATTAAGATCTTCAAGGACGATGATTATTACTATCTGGATGGCTCGGATCGTTCGCAGTCGAATTGGATGCGCTATGTGGCCTCTGCGTATAGTTTGTCTGTCATGAATCTGGTGGCTTGCCAGCATCTGGAGAATATCTATTTCTATACTACCCGCGACATATTGCCCAACGAGGAACTGATGGTCTGGTATTGCAAGGACTTTGCCAGCCGTTTGGGCTACGATGTGGATCCGGAGCGCACTATTTTTGGTGCCTGCAAAcaggatgtggatgtggaagaggatgaggatgacgaACTGCCGCACAAGAAGCCGCATTATGCAATGCCCGCACCCGAAATACCCGCCGAGGTGGCTGTCAGTCACATTACCTATGTAATGGGTCTGCATTTGCCTGGTGCGCCGCCAGCTGCGGCGGCACCGCCACCAGCCTCCCAATGCTGTCGTCGTGCCAGTCCACCCGCCCATGTTACCactaccagcagcagcaatatcaacaacaacgccaATTCCAACTCACTTCATCCGCATATACAGCATAGTCGGCACGCCTCTGTCATCATTGGACAGGATCGATCGCCTTTGAACAGCAACTGCGATAAGGAGACGGCCGGCTCGCCGCTGTGCGGCAAGGATGCGCACTATGAGCATCAGCTGACGCCGCAGGATGGCAGCGTGAGATCCGTGCGCTCTGATGAGGGCTACCACAGCAACGAGTGCCAGGAGGATGGACTGACGCCGCCGGAGGATTCCAGCGATAGCGAAAGCGAGCACAACTATGTGCTCGACTGCTCCAAGAAGGCCATTGCGCCCAAGGAGACGGTCATTGCGCAGGCGCAAAAACCCAGCAGCGTTACACCACCAGCCACCACGCCCACCGCCGTCACGCCCAGCTGTGAGTCGGACAAGAACGAGTATCGCAAGTTCAAGGTTAAAATGCCACTGAAATACGAGTTCAAGAACAAGAGCTGTGTGAAAACGGAACCAATCAAGGATGTGGATGAGCAGCTGCCACCAGCCGGCGTCGGcctggaggaggaggagctgcACGAGCTGCATGTGGCTGCCGTGCACTCCGAGGACTCGCTCTGCCCGCCCAGCACCACCACAACGCTCGGCGAGGAGCCGCATATGCAACATGTGGAGCCAACCAATCCACAGCCCGCCTCCTCGACGGTTATTGTGCTAGAGCACAATTCTGGTGGTCAGACGCGCACCATCGTGCCGCTGAGCAAGCCCTACTATGAAGCCGATCCGCCCGGCGAGCGTTATGTGCGCTTTACGCAGCCCAGCTCCAGCATATTAGAGACCATACTGACCAGCCAGCATCGCCTGgaggccgctgctgctgccgcgaATGCCTGCAGGCAGGCAAATGCTGCCACGCCGCCGCCCACATCGCCCACGGAGATGGCCTACAGCTACAAGAAGTCGCAGCGCTATGGCAACGCTGTAAGTCCCGATTCCAGCTCGAATTTGGGCCAACCCCAAGAGCTGAGCGCCGTTGTGGCCGAGCAGGAGCTGAGCCTGAGCCGCGGAGCTCTGATCAAGGGCGAGTGCTCGCCACCACCAGGCGCAACGCATCATCACCACAATGTCATCTATTCGCCCACAAGGACACATCATGCGGCCTATGAGCCTGGCAGCCACTCGCCCAGCTATGCTGGCTATGCGAGCTATCCTGGCGCGCAATCCTTGCATGCGGCAACCTCAACGTTCCACTCGCCCCCGCACAGCTCACACTCGCCCTTTGATCGCCAATCGAATGCATCCAGCGGCGGCGGCTCCGCCTCCAATTTGCATCTGCTGCAGAGCAGTACACAGATGTTGAATCATCCGTTGATGCAGCCGTTGACGCCGCTGCAGCGCCTCTCACCGCTCCGCATCTCGCCGCCCAGCAGCCTCAGTCCGGATGGTAACTCCTGCCCGCGCAGCGGCAGCCCCCTGAGTCCTAATTCGTTGGCCTCGCGCGGCTATCGCTCGCTGCCGTATCCTTTAAAGAAAAAGGATGGGAAGATGCACTACGAGTGCAATGTGTGCTGCAAGACCTTTGGCCAGCTGAGCAATCTCAAGGTGCATCTGCGCACTCATTCCGGCGAGCGTCCCTTCAAGTGCAACGTGTGCACCAAGAGCTTCACCCAGCTGGCGCATCTGCAAAAGCATCATTTGGTGCACACGGGCGAGAAGCCGCATCAGTGTGACATATGCAAGAAGCGTTTCTCCAGCACGTCCAATCTGAAGACGCATCTGCGGCTGCACAGCGGCCAGAAGCCCTACGCCTGCGATCTGTGCCCCCAGAAGTTTACACAGTTTGTGCATCTGAAGCTGCACAAGCGTTTGCATACCAACGATCGGCCCTATGTCTGCCAGGGCTGTGATAAGAAGTATATCAGCGCCTCTGGTCTGCGAACGCACTGGAAGACGACCAGCTGCAAGCCCAACAATCTGGAGGAGGAACTGGCCATGGCCGCAGCAGCCACCTCCGAGTGTCTGGACAAGGATCTGCCGGAGCCGGATTCGCGTGAGGCATatgagcagctgcaacagcacaTGCATCCGGTGCATCCCAGCTTGCGGCACTTAACGGGCGCTCAGTCGCCACCGCGCCTGATACCGCTGAGCGGCAGCAATGGCCAGTCGCATATGCACATGCAACAGTTGCAGGCACATCAGCAGCATCCGGGCGGAGCAGCGCCGCCTGGCCACCTAATGCTGCCACAGCAGTCGCCACACGGCGCTCCGCCCATGCTGCTTACCACTGCCAATCAGCTGCCACCACCCACAACGCCACATcacatgcaacagcagcagcaacagcagcagcagcaacaacagcagctgcagcagcaacagctgccacaGGCCTCACCTGGCCGACAGGCGGTCACACATCAGCATCTGGGTCCACCGCATCATATGACGCAGCATTCGCCCAAATCGCTGAAGCCTTTGCAGGACACTGGCTACTTACATGGGCCGCATGTGCAGGCCCAGGAGAATCGTCCTTCCGTGATTGAGTCCTCCAATCAGCCCATGATCATTGAGTGCACGTAG
Protein Sequence: MHGLHHHHQQQQQQQQQQTPQPQQVTQTAATMKTAGNPQQQQQQQQQQQQQTHIAIQQQQQQQQQHTHPHHHPHPQAQHNTHPHPHQHPHHHAKLLRRSRSRSRSPTPDGTQDYDVTRMREEDFERLAVYLVPDVQAERGLPNRADKTLPRSLTLKSSMVYSTPNVKTEGVWSSGVIPRGTRFGPFEGIPTSNYPNDKNKARYFWRVQGTRHITYGNIKIFKDDDYYYLDGSDRSQSNWMRYVASAYSLSVMNLVACQHLENIYFYTTRDILPNEELMVWYCKDFASRLGYDVDPERTIFGACKQDVDVEEDEDDELPHKKPHYAMPAPEIPAEVAVSHITYVMGLHLPGAPPAAAAPPPASQCCRRASPPAHVTTTSSSNINNNANSNSLHPHIQHSRHASVIIGQDRSPLNSNCDKETAGSPLCGKDAHYEHQLTPQDGSVRSVRSDEGYHSNECQEDGLTPPEDSSDSESEHNYVLDCSKKAIAPKETVIAQAQKPSSVTPPATTPTAVTPSCESDKNEYRKFKVKMPLKYEFKNKSCVKTEPIKDVDEQLPPAGVGLEEEELHELHVAAVHSEDSLCPPSTTTTLGEEPHMQHVEPTNPQPASSTVIVLEHNSGGQTRTIVPLSKPYYEADPPGERYVRFTQPSSSILETILTSQHRLEAAAAAANACRQANAATPPPTSPTEMAYSYKKSQRYGNAVSPDSSSNLGQPQELSAVVAEQELSLSRGALIKGECSPPPGATHHHHNVIYSPTRTHHAAYEPGSHSPSYAGYASYPGAQSLHAATSTFHSPPHSSHSPFDRQSNASSGGGSASNLHLLQSSTQMLNHPLMQPLTPLQRLSPLRISPPSSLSPDGNSCPRSGSPLSPNSLASRGYRSLPYPLKKKDGKMHYECNVCCKTFGQLSNLKVHLRTHSGERPFKCNVCTKSFTQLAHLQKHHLVHTGEKPHQCDICKKRFSSTSNLKTHLRLHSGQKPYACDLCPQKFTQFVHLKLHKRLHTNDRPYVCQGCDKKYISASGLRTHWKTTSCKPNNLEEELAMAAAATSECLDKDLPEPDSREAYEQLQQHMHPVHPSLRHLTGAQSPPRLIPLSGSNGQSHMHMQQLQAHQQHPGGAAPPGHLMLPQQSPHGAPPMLLTTANQLPPPTTPHHMQQQQQQQQQQQQQLQQQQLPQASPGRQAVTHQHLGPPHHMTQHSPKSLKPLQDTGYLHGPHVQAQENRPSVIESSNQPMIIECT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610151;
90% Identity: iTF_00803877;
80% Identity: -