Basic Information

Insect: Hirtodrosophila histrioides
Gene Symbol: PRDM5
Assembly: GCA_037075165.1
Location: JBAMCL010000013.1:472936-474907[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.19 12 6.8 0.2 3 23 294 315 293 315 0.91

2 10 0.00011 0.007 17.0 0.8 6 23 324 341 324 341 0.99

3 10 5e-06 0.00033 21.2 0.3 1 23 347 370 347 370 0.98

4 10 0.00051 0.034 14.8 1.0 1 23 382 404 382 404 0.98

5 10 0.0037 0.25 12.1 5.2 1 23 411 434 411 434 0.96

6 10 1.5e-05 0.001 19.6 1.8 1 23 440 462 440 462 0.96

7 10 0.12 8 7.4 0.5 2 23 471 492 470 492 0.96

8 10 0.00012 0.0079 16.8 3.1 2 23 498 520 497 520 0.95

9 10 7.4e-07 4.9e-05 23.8 0.4 2 23 527 548 526 548 0.96

10 10 0.00023 0.016 15.9 4.4 1 23 554 577 554 577 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.19	12	6.8	0.2	3	23	294	315	293	315	0.91
2	10	0.00011	0.007	17.0	0.8	6	23	324	341	324	341	0.99
3	10	5e-06	0.00033	21.2	0.3	1	23	347	370	347	370	0.98
4	10	0.00051	0.034	14.8	1.0	1	23	382	404	382	404	0.98
5	10	0.0037	0.25	12.1	5.2	1	23	411	434	411	434	0.96
6	10	1.5e-05	0.001	19.6	1.8	1	23	440	462	440	462	0.96
7	10	0.12	8	7.4	0.5	2	23	471	492	470	492	0.96
8	10	0.00012	0.0079	16.8	3.1	2	23	498	520	497	520	0.95
9	10	7.4e-07	4.9e-05	23.8	0.4	2	23	527	548	526	548	0.96
10	10	0.00023	0.016	15.9	4.4	1	23	554	577	554	577	0.96

Sequence Information

Coding Sequence: ATGATCTGTCGCTTGTGTTTAAAAAGCATAAACGCAAACAATGCCGTCTACCTATTCGAGACCAACGAAACCCTGGCCGAATCCTCGCTGCTCAAGATGATAGCCAAGTTTTTGCAGCTGGAAATAATGCCCGATGACAGCATTTCGACAGCCATTTGCCACGAGTGCTGCGAGCACTTGGAGGACTTCAATAACTTCTGGCAGCTGGTGGAGCAGAAACAGGGCACACTGAATAAAGAGTTCCTCAACGTGGACGTCGATTGCGTGGCCCTCAAATGGACGGGCGGCATTGATGTGGATGTGAACATTGATGAGCTGCCGCTGGTGGCCGACGAGATGGACGAGAAGCCACTGGATATACACAATCTTAGCCTGCTCAGCAGCGTACTGGATATAAATGTGGACAGTGTCGAGCTGCCGCAGTTGTCAACGACGCCAAAAGATGAACGGAATGCAgcgctgttgccgctgcaagCAACCGAACTAGACTATGACAATGACGATGACATCGATGAGAAGCCACCCATGATTGAGAGCAGCGATAGTGCGCACAACACCACCAcagatgacgatgatgatgatgatgatgacgaggTGCCGCTGGTCAAGCTGCAGCATAAGCTTAAGCCGAAGCGCAAAGCGCGCGTCGCTTACCGCAATCAGCGTAGCCTAACGCTAGCTCAGGAGCTGGATCAGCTGCTCGAGGATAACGCAGGTGTGggcacaagcagcagcaaggtGCGCCGCAAGAAACCAACGGACTCCAGTCTGGCCATCGATGGCCTGCCGGCACCGCTGGAGCGCAAGCCCAAGGGCTGCTCCCGTGCGCAGCTGACAAAGCGCTACGAGGAGTCCATTGCCAGCTATATGAACGCCGACTGTGATCTGTGCGACTTTAGCGCCAAGTATATGTCGCAGCTAAAGGTACACTTTCTGGAGGTACATCAGCGGGATGCATACCTCAAGTGCTGCAACAAGGTGTTTAATCGCGCCTCCAAGCTAATGAATCACATACGCAAGCACATCAATCCCAAGCTGTTCACCTGTTCCATATGCAATAAGTCGCTCAGCTCGCAGGACTATCTGGCCACGCATATTGAGACAGTTCACAATAAGGTCGCCCAGATTGGCAAGGTGCTGAAGTATCCCTGCTCCAAGTGTGAGCGCACCTTTAGCAGCGAGCGCCGCCTGGGCAATCATCTGCTCAAGCACGACACGGATCAGTTGGAGCACAGCTGTCATATTTGTCTAAAGAACTTTGCCAACGTGCATCGGCTGCGCCGGCACATTCAGTCTATACACGAGGATTTGCATCCGCATGTCTGCGACATATGCGGCAAGAAGTTCAAGTTTAAGCCCTCCTTTGAGCGACACCTGCTGGAGCATCAGGGCGTCGTTGCACCGGCCATGGAGTGCCCCGTCTGCGGTGTCTGGCTGAAGAACGAGCACAGCCTGCGGCTGCATCGCTTCACACACGATAGCACCGACACAGTATGTCCGCACTGCTCCAAAAAGTGCAGCTCGCGAACGGCGCTGCGTGCCCACATCAAATATGCCCACAAGCTGACCACCAATCTGCCGTGTACGTACTGCGACAAGACCTTCAAGCAGCAGCGCAATCTGGACGAGCATATGGCCATACACACCGGCCTCCAGCTGTACAATTGCCCCCACTGCCCCAAGGAATGCCGCTCCCGGTCGAACATGTATGTGCACATCAAGCAGCGGCATGCGGATGAGTGGCTCAAGGCAAAGATGGCCCGCTCCCACAATCCGCAATTCAAGCCACTAGCCTAG
Protein Sequence: MICRLCLKSINANNAVYLFETNETLAESSLLKMIAKFLQLEIMPDDSISTAICHECCEHLEDFNNFWQLVEQKQGTLNKEFLNVDVDCVALKWTGGIDVDVNIDELPLVADEMDEKPLDIHNLSLLSSVLDINVDSVELPQLSTTPKDERNAALLPLQATELDYDNDDDIDEKPPMIESSDSAHNTTTDDDDDDDDDEVPLVKLQHKLKPKRKARVAYRNQRSLTLAQELDQLLEDNAGVGTSSSKVRRKKPTDSSLAIDGLPAPLERKPKGCSRAQLTKRYEESIASYMNADCDLCDFSAKYMSQLKVHFLEVHQRDAYLKCCNKVFNRASKLMNHIRKHINPKLFTCSICNKSLSSQDYLATHIETVHNKVAQIGKVLKYPCSKCERTFSSERRLGNHLLKHDTDQLEHSCHICLKNFANVHRLRRHIQSIHEDLHPHVCDICGKKFKFKPSFERHLLEHQGVVAPAMECPVCGVWLKNEHSLRLHRFTHDSTDTVCPHCSKKCSSRTALRAHIKYAHKLTTNLPCTYCDKTFKQQRNLDEHMAIHTGLQLYNCPHCPKECRSRSNMYVHIKQRHADEWLKAKMARSHNPQFKPLA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610817;
90% Identity: iTF_00803785;
80% Identity: -