Basic Information

Insect: Hirtodrosophila histrioides
Gene Symbol: dcaf8
Assembly: GCA_037075165.1
Location: JBAMCL010000515.1:1332706-1340063[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 4e-05 0.0027 18.3 2.4 1 23 325 347 325 347 0.98

2 11 0.00017 0.011 16.4 2.8 1 23 432 454 432 454 0.98

3 11 0.00043 0.028 15.1 1.6 1 23 642 664 642 664 0.98

4 11 0.00092 0.062 14.0 1.9 1 23 670 692 670 692 0.94

5 11 0.099 6.6 7.6 1.2 1 23 701 723 701 723 0.98

6 11 5.4e-07 3.6e-05 24.2 1.8 1 23 729 751 729 751 0.99

7 11 2.2e-05 0.0015 19.1 4.9 1 23 757 779 757 779 0.99

8 11 5.3e-05 0.0035 17.9 2.6 1 23 802 824 802 824 0.98

9 11 2.6e-05 0.0018 18.9 4.4 1 23 830 852 830 852 0.98

10 11 6.8e-06 0.00045 20.7 0.9 1 23 862 884 862 884 0.98

11 11 1.3e-05 0.00084 19.9 3.2 1 23 890 912 890 912 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	4e-05	0.0027	18.3	2.4	1	23	325	347	325	347	0.98
2	11	0.00017	0.011	16.4	2.8	1	23	432	454	432	454	0.98
3	11	0.00043	0.028	15.1	1.6	1	23	642	664	642	664	0.98
4	11	0.00092	0.062	14.0	1.9	1	23	670	692	670	692	0.94
5	11	0.099	6.6	7.6	1.2	1	23	701	723	701	723	0.98
6	11	5.4e-07	3.6e-05	24.2	1.8	1	23	729	751	729	751	0.99
7	11	2.2e-05	0.0015	19.1	4.9	1	23	757	779	757	779	0.99
8	11	5.3e-05	0.0035	17.9	2.6	1	23	802	824	802	824	0.98
9	11	2.6e-05	0.0018	18.9	4.4	1	23	830	852	830	852	0.98
10	11	6.8e-06	0.00045	20.7	0.9	1	23	862	884	862	884	0.98
11	11	1.3e-05	0.00084	19.9	3.2	1	23	890	912	890	912	0.98

Sequence Information

Coding Sequence: ATGGATATTTGCCGCGTTTGCCTGAGCAGCTCACCGGGCCTAGCTGACATGTTCACCGAACGCCCACTGCCCGAACATCAATGCAGCCTCGCTGACATGGTAAACGAATTTGTCGACTTCATCGTAAAACCAGATGACAAGCTCACGCAAAAGATGTGCGTACTGTGTAGTTTGAATCTGCAAATTGCGTACAGATTCAAACTCAGCTTCGAGAAGAACTATCAGTTGCTGAGCAAGAAACCAATCAAAATCGAATGCGACAACGTTGTGCAACAGAACGTGCAACAGAAACCATCATCTATGAATAACTGCCCCGAGCCGGGCTTACACCCCTCTCAGttcagcagcaacatcgaTGGGCGTGGCAGAAACGCATCGAGTGACCAGATAGAAGTCAGCACCAAGACAATGAGAACCGAAGACGATCTCACTGTGGGTATGTTAGAAAGGGACTTGTCCGATGGGATGGAGCGAAATGCGAGCACTCTAATCGATCCGTCTCCATCCAATGATAGCAATGAACCTAGCTTGCGCAATTCGCTCCGTGAGGCCACACATAAGAGCTTTGCGGAGTACAACCCAAAGAGCAGCAGCGCATCGTGTGACGAGCATTCCACACTCATCGAAGCTGATATCTTGGAGGGTGCTACAAGCAGCAGAAATAGCACATTGAACGACGAAAGTGTAAAGGAACCCGAAACAATCAACATAAGTAGCAGCAGGAGCGCAAAGAGTGCCGTAGATTCTCAGTTAGAGAGCTCTGTGTTGCAGAACATCCCTGAGAATCCGCTTTCACCTAATGCCGGCTTGCAACTACAGCTCAATACCAACAGCCTAATTAATGGTCTTGACAATAGCTCATCGAATAACATGATACCGGTCAATGAGAGGGACAAGGAACCCGAAAcaatcaacagcagcacaagcaAAAGGAGTGGCGCAAATTCAAAAGGCATTCACAAGAAAAAGGAACACAAGTGTGACCAGTGTCAAAAGGTCTTTGGGGACAGTTGGAAACTTCGGAGGCACCTCAACTCCCATATCAGCAGTAAAAAAATTCACAGTCAGCAGAAGGATCGCTCTGCGTTGCAGAACATCCCAGAGAATCCGTTTTCACCTAATGATGGTTTGCAATTGGAGCTCAATACCAACAGCATTATCAATGGACTTGACAAAAGCTCATCGAATAACATAATACCGGTCAATGACAGGGACAAGGAACCCGAAAcaatcaacagcagcacagACAAAAGGAGTGGCGCCGATTCAAAACGCATTCACAAGAAAAAGGAACACAAGTGTGACCAGTGCCAAAAGATCTTTAGGGACAGTTGGCAAATTCGAAGGCACCTCAACTCCCATATAAGCAGTAAAAAAAATCACAGTCAGCAAAAGGAGTGCTCTGCGTTGCAGAACGTTGCATCACCGAATGACGGTTTGCAATTGGAGCTCAATACCAACAGCATCATTAATGGACTTGACAAAACCTTATCGGATAACGAGATAGAGGTCAGCAGGCTGTTGGTCAAAATATTAGAAGACGACATGAATGTCAATATGCTGGGAACAGACGTGGTCAAGGAGATGGAGAAACAGGAAAACCAATCGTTGAATTTGCCTTCATCGAATGACCGTGTTGAAGACCATGAATCCAGCCCCAAGGAAGCCAACACTCGCAAATCTCAGCGCTATCCGATCCGTAGGAGCAACCGTAAGAGCTACGCGGAGCCCAACACAAGGGGCAGCAGCGCATCGAGTGACGAGCATTCCGACATCGAAGCTGATTTCCTAGAGGGTGCTataagcagcagcaatagcacTTCGAATGATGAGGGTGAAAAGGACCCCGAAACAATCAagacaagcagcagcaggagtgCAACGAGTGACGCAGATTCAAAACGCTTTCACTTGAAAAAGAAACACAAGTGTGACCAGTGCCAAATGGCCTTTGTGGACATTACGAAGCTTCGGAGGCACATCCAATCCCACACTGGAGAACGCCCATATAAATGTTCCCAGTGTCCAAAGTCCTTTGCGTCCAATTATTCTCTCCAATTTCACGAATCAAGACATAACAATCCCAATATAGAAAAGCGATACAAGTGTGACCAGTGCCCAGCAGCATACCACTGGAACACCTCCCTTCAGCACCACATATTAGTCCACAAAGGTGAACGTCCATACAAGTGCGACCAGTGCCCAAAGTCCTTTACGAGGACGTATCTCCTCAAGGATCACATGAACATGCACACTGGTGAACGCCCATACAAGTGCGACCAGTGCCCAAAGTCCTTTACGAGGACGCATCGCCTCAAGGATCACATGAACAAGCACACTGGTGAACGCCCATACAAGGCGTCTCTCCAGCTGCATTTGCTCATCCACAATGGTGAACGCCCATACAAGTGCGAACAGTGCCCAAGGTCCTTTGCCTCGAAGCATCGCCTCAAGGATCACATTAACCAGCATACTGGTGAAAGCCCATACAAGTGTGACCAGTGCCAAAAGACTTTTAAGGGTCGCCAAAATCTCAAGCGTCACAAAACAACCCATATTAGCATTCAGGAtaggaataataaatacaagtgCGACCAGTGCCCAAAGTACTTTGCGTCGAAGTATCAACTCAAGGAGCATATAAACGGGCACACTGGTGAACACCCATACAAGTGTGACCAGTGCCCAAAGTGCTTTATGAGGAAGAATCAACTCAAGGATCACATGATCGAGCACACTGGTGAACCACCAGCCTGTAAGCGACAGAGACGCAATAGCATGGACTATGAAAGCTGTAATGAGGCCGGTAGcgaagcagcagctggagctgcatCTGAAATGGACACAATCCTGACTGGAGGGAAAGAAACTGGAATCGTTAATAGCGacagtaacaataataacaacaatttagaAGAGCCAATGGAAACTGACAATGCTGCTTGCAACGCTGATCAAAATGACGAACATGCGGATATCCACACGGTTGTCAATATGCCCACTCCCCGTTGGGCAGAGCAATCGCCCAATATCTTGCTGCACAGCCTGGCAGTTGATGCACCAGTAACTGATAAGGTTACAACAGGCACACAGACAGACGACACACCTGTGGGCATCTACAGTTTTTCCCCAAATTCAAGCTTAAACGTGAACCATGCTTCTAGTGACGGCGAGCGGCATGCCAGTCCGATATTTGATATGGTGTCCATAAATATAGACTGGGAGTACTCCAGCAGTGATGACAGCAGTGAAGACAGCAGTGATGACAGCAGTGATGCCGATGAAAGAGCCATAAATATCACTAACGACGGCATTAAGTTTTGGGACCACTATTACCCACCAGGAGATAGGAAAGTTTGTCCAACTGAATATGTGCTTACCAGTCCCCGCAGAGAGGATATTAGGGAACGAATTGAGTCTGCTGTTAACAAGGTCATGTGCAAATCAAAATCGTCCTACAATTGGAACATTGCCGAGGAGCTGATGCGCCGagaaaacaatttgattaatCGGATTACCTGGCGTGGCGGTCACACCTCCGCCCTGAGCTTTAGCCAGGGCTATTGCGGATCGCGGCAATTGGTAGAGCGCATGGAGGTTATTAGCGGTATGAGCACCCATTCGGCTTGGATAAACTGCATGAATTTCAATAGGTCGGGCGATCTTATTTGCGTCGGATCGACAAAACCGCCAGTCGTTGTGTGGAACTGGGAGAACAGGAAGCCAACAACCGCCTTCCAATCGGGCCACAGATGTGAAATATTGCAAGCAAAGTTTGTCGACAGCGACGGGTGCCTGGACATTGTTAGCTCGGGATGCGACGGTCAGGTGCGACGTATCATTATTCCGCCGTCCGGCGGCTCAAGCATCGAGTCCGAGGGTCTGTACAGTCACCAGGATGCAGTTTACAAGTTTGTGACGGTGCCGCAAAGCCGACAGGAGATTATAAGCGCTGGCCAAGATGCGGTGGTCAAACACTTTGATTTACGCACAAACACATGTACAACAACGCTGCCCTGCGTCTCCGTGAGCGGCGAAAAACGCATTAGGCTCTTTAGCATTGATCATCATCCATTTGCGCCGGAGTTTTGCGTCAGTGGCAACAATGGCAAGCTGCTCGTCTACGATAGGCGCCAGCTCACCAAGGCCGTACATGTTTTGAAACCCACGGATATAAAGAATCCAAAAACCGCGATTAACTCCGTAGTCTACAGTCACAACGGCAGCGAGATTCTCGCCTCGTACAGCAATGCGGGGATTTACCTTTATGACAGCCGCAACTACCAGAAGGGCGAATACCTGCAGTGTTATGAGGGTCATGTCAATACCATCCGAATCAAACCTGTCCACTTCTTTGGGGCTAACTCCGAATTCGTAGTCACTGGCAGCGACTGTTCTTACATTTTCTTTTGGGATAAGAATACAGGGGCTGTGGTTAAATTTCTGAAAGCTGATATTTTTAGCTCTGTCTGCTGTATGGAACCACATCCATGGATGCCTCTACTAGCCACTTCTGGCATTGAGCACAATATCAAGATTTGGACGCCCACTGGCTTGCCTgAAGCGCCGGACTCAGATGAACTTAGGGAAAGGTTGAAACGAAGCTTCAAACGTTTAATTAAGTCGGAAAAGCATTGCGATTGTGACGAGAGCGAGGAATACTCCGACTACTGA
Protein Sequence: MDICRVCLSSSPGLADMFTERPLPEHQCSLADMVNEFVDFIVKPDDKLTQKMCVLCSLNLQIAYRFKLSFEKNYQLLSKKPIKIECDNVVQQNVQQKPSSMNNCPEPGLHPSQFSSNIDGRGRNASSDQIEVSTKTMRTEDDLTVGMLERDLSDGMERNASTLIDPSPSNDSNEPSLRNSLREATHKSFAEYNPKSSSASCDEHSTLIEADILEGATSSRNSTLNDESVKEPETINISSSRSAKSAVDSQLESSVLQNIPENPLSPNAGLQLQLNTNSLINGLDNSSSNNMIPVNERDKEPETINSSTSKRSGANSKGIHKKKEHKCDQCQKVFGDSWKLRRHLNSHISSKKIHSQQKDRSALQNIPENPFSPNDGLQLELNTNSIINGLDKSSSNNIIPVNDRDKEPETINSSTDKRSGADSKRIHKKKEHKCDQCQKIFRDSWQIRRHLNSHISSKKNHSQQKECSALQNVASPNDGLQLELNTNSIINGLDKTLSDNEIEVSRLLVKILEDDMNVNMLGTDVVKEMEKQENQSLNLPSSNDRVEDHESSPKEANTRKSQRYPIRRSNRKSYAEPNTRGSSASSDEHSDIEADFLEGAISSSNSTSNDEGEKDPETIKTSSSRSATSDADSKRFHLKKKHKCDQCQMAFVDITKLRRHIQSHTGERPYKCSQCPKSFASNYSLQFHESRHNNPNIEKRYKCDQCPAAYHWNTSLQHHILVHKGERPYKCDQCPKSFTRTYLLKDHMNMHTGERPYKCDQCPKSFTRTHRLKDHMNKHTGERPYKASLQLHLLIHNGERPYKCEQCPRSFASKHRLKDHINQHTGESPYKCDQCQKTFKGRQNLKRHKTTHISIQDRNNKYKCDQCPKYFASKYQLKEHINGHTGEHPYKCDQCPKCFMRKNQLKDHMIEHTGEPPACKRQRRNSMDYESCNEAGSEAAAGAASEMDTILTGGKETGIVNSDSNNNNNNLEEPMETDNAACNADQNDEHADIHTVVNMPTPRWAEQSPNILLHSLAVDAPVTDKVTTGTQTDDTPVGIYSFSPNSSLNVNHASSDGERHASPIFDMVSINIDWEYSSSDDSSEDSSDDSSDADERAINITNDGIKFWDHYYPPGDRKVCPTEYVLTSPRREDIRERIESAVNKVMCKSKSSYNWNIAEELMRRENNLINRITWRGGHTSALSFSQGYCGSRQLVERMEVISGMSTHSAWINCMNFNRSGDLICVGSTKPPVVVWNWENRKPTTAFQSGHRCEILQAKFVDSDGCLDIVSSGCDGQVRRIIIPPSGGSSIESEGLYSHQDAVYKFVTVPQSRQEIISAGQDAVVKHFDLRTNTCTTTLPCVSVSGEKRIRLFSIDHHPFAPEFCVSGNNGKLLVYDRRQLTKAVHVLKPTDIKNPKTAINSVVYSHNGSEILASYSNAGIYLYDSRNYQKGEYLQCYEGHVNTIRIKPVHFFGANSEFVVTGSDCSYIFFWDKNTGAVVKFLKADIFSSVCCMEPHPWMPLLATSGIEHNIKIWTPTGLPEAPDSDELRERLKRSFKRLIKSEKHCDCDESEEYSDY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -