Hhis000262.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Hirtodrosophila histrioides
Gene Symbol
-
Assembly
GCA_037075165.1
Location
JBAMCL010000013.1:2174207-2177170[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.024 1.6 9.5 1.4 2 23 143 164 142 165 0.93
2 12 4.4e-06 0.0003 21.3 2.9 2 23 179 201 178 201 0.96
3 12 0.013 0.89 10.4 9.1 2 23 474 495 474 495 0.97
4 12 2.3e-06 0.00015 22.2 2.9 1 23 501 524 501 524 0.95
5 12 0.0014 0.091 13.5 0.5 1 23 529 552 529 552 0.93
6 12 7.6e-05 0.005 17.4 5.5 1 23 570 592 570 592 0.96
7 12 0.00021 0.014 16.0 1.3 1 23 597 619 597 619 0.98
8 12 4e-05 0.0026 18.3 1.7 1 23 625 647 625 647 0.95
9 12 0.00013 0.0089 16.7 0.8 1 23 653 675 653 675 0.98
10 12 4.1e-07 2.7e-05 24.6 2.7 3 23 683 703 682 703 0.99
11 12 2.8e-08 1.9e-06 28.2 1.0 1 23 709 731 709 731 0.99
12 12 1.9 1.2e+02 3.6 5.2 1 19 736 754 736 759 0.88

Sequence Information

Coding Sequence
ATGCCTGACACCTATAGCCAATTCGATGCGGAGCGCGTCTGTCGCGTTTGTCTGCGCGAGGTGGGCGATTTCTACTTCATCTATGATGAGGCGCCCGTCGAGCAGGGCGCGAATATTGCCCAAATACTTAATGAATGCACACGCTACACCTGTGAGCGGTACGACAAAATGCCCCATCACATGTGTGACACCTGCATCAAGGCCGCCTGTCAGGCGTATCGATTCAAGCGGGACGCTGAGAAGGCCTATCGCTCCCTGGTGGCGATGCTGGGCCGCACTCCGATAGCCAAGCCAAACAGCAACGATGTGTGCACCCAAACCGAGCAGCTGCCCATGCTGCCCTGCGGCATTTGCAACGATAAATTTCTCAACATACTGGATCTACGCATGCATCGCAATCAACAGCACAAGCAACTGGTGGAGCTCAAGTGCAAGCTGTGCGATGCACAGTTCCAGCAGGTGCGTCAGCTGCGCAACCATCTCGTCGAGCATCATGATCAACAATCGCCACCACCGTTGCTGCGCCGCCGTCTGGAGTGCCGCGTTTGCCAACGCACCTTCTCGCGACGGGATCACATGTTGCGCCATATGCGCACCGTGCATAAAGTGGATACGATAGATGGCCAGCGCGGGACGCTGGCCGAGGAGGCGGAAGCGCTGTCATCGGCGGTCTGGCCGTCCATTGACGAGGCAACCATGCAAAGCGGCGATGAACTGGAGTCGGCTGCCGTTTTACTCAATGCCGATGCCTGCTCCGATGATGAAGACAACGAGCATAACGAGAGTGGCTATCAATACCATACAAATCCCATATCAAGCAACGAGGAGCCCGATGACGAAGAGGCTGATGCCGAAGCCAAAAAATCACTCTGGCTGCACATTAAGCCCGAGCCGGAATTGGAAGCGGACCCAGACAATTGTCCCGTCACCGAGGTCGCCCAGGTGAAGCGCGAGAGGCGACGACGCAGAGCTAAGCTTGAAGTGGCGGACGAGCGCGCAGAGCAACAGAAGAGTGCGGCCAGTGCTCTGGCGGAAACCGAGGTCAAAGAAGAGCCTCTGGCCGCTGTCGGTGAGCAACAACTTGCCATTAAGCAGGAGCGACAGCGCATTGATAGCGTCAATGAGGATGACGAGGAAGAGTTTGAGCTGGAGGTGACTGGAGCGGACATGTTGCACACCAGCGATGATGAGGAAGATGAAGAGGAGTTTTGCAATGAGGAGAGTGACACCGATGGCATtggcgatgatgatgaagaaGATGAGCCCGGCGCTGAAGTTGAATCTGAGGAGGGCAAGGCACAGCTGACACAGACGGGTCAAGTTGAAATTGTGCGTGAGTATCTGCAGGAACCAAAAGCGAGCAAGCAgcgacgtcgtcgtcgcaACAAACAGGCTGAAACGGAGGTAAATCCAGAGAATCGCTGTGATGTTTGCCAGCGCACCTTTTCCCGCCATTGCCATTTGTTGCGTCATAAGTTGTCGCATTTAGAGAAGAAGCCGCATAACTGTCCGCATTGCCCCAAAGCGTTTGCGCGCAGCGATCATCTGAAGGCGCACGTGCAGAGCCTGCATGGCAACAAGGAGCACAAGTGCATACTATGCGATGCGGCATTCTCCCGCCCCGATGCACTCGAACGGCACAAGATGAGCAAGCACAATGGCGAGGGCCTGGACGCCAGCAGCGAGCTCAAGCTGCAAATGAATGACCACACGTGCGAATACTGCTCCAAGCGCTTCTCAAGCAAAACGTACCTGCGCAAGCACACGCTACTCCATACCGAATTTCTCTATGCGTGCAAGAGCTGCGACGAGACATTCAAGgagcgccagctgctgcgCAACCACGAGAAGACCCACACCGGTCAGCGGAACTTCCTTTGCTGCATATGCGGTGATAGTTTTGCCCGCAATGATTATCTGCGCGTTCACATGCGGCGCCACAATGGCGAGAAGCCATACAAATGCCGCTTCTGTGTCAAGGCATTTCCCCGCGCCACAGATCTTAAGGTGCATGAGCGcTATCACACCGGCACAAAGCCCAATCTGTGCAACACATGCGGCAAGAGCTTTCATCGCGCCTACAATCTGACCATTCATATGCGCACACATACTGGAGAGCGTCCCTACAAGTGCGACCAGTGCCCTAAGAGCTTCAGCCAGAGCAATGACTTGAAAGCGCACATACGCCGGCACACCGGCGAGCGGTATAAGTGTCCACACTGCGATGCATACTTCCTGCAGCTGTACCATATGCGCAACCATTGCCTGAGTGCCCACAACATGCATATTGAGACCAAAACGGGTCGGTTGCAACGCACGGGCCTGCTGGATGAGCCCAATCACTCGCATCTGACCACTGTGGTAATACCGCCGTCTCGGTTTCAGCAAACAACGGCTGATTCACCAACGATGGCGACCGTTACAGGGCAGCTGCCTGCTGCAGCGGCAATCGCACCGCCACTTATTCATTCGCCGGTGACCTACAATACAACGTCGCCAGTATCCGTAACGGTCCCCGTGTCAGATAGCGCCGGATTTGTGGGCTCTACGACCAGTGCGACCGCTACGGCAACGACGCCCTTCGGTGCATTCAATATAACGCCTGTCGTAATGGCGCATCTCATGTACAACCATGGTGGCAACAGCCAGCAGAGCAATGCCAGCGGAAGCGAGACAGGAAAATAG
Protein Sequence
MPDTYSQFDAERVCRVCLREVGDFYFIYDEAPVEQGANIAQILNECTRYTCERYDKMPHHMCDTCIKAACQAYRFKRDAEKAYRSLVAMLGRTPIAKPNSNDVCTQTEQLPMLPCGICNDKFLNILDLRMHRNQQHKQLVELKCKLCDAQFQQVRQLRNHLVEHHDQQSPPPLLRRRLECRVCQRTFSRRDHMLRHMRTVHKVDTIDGQRGTLAEEAEALSSAVWPSIDEATMQSGDELESAAVLLNADACSDDEDNEHNESGYQYHTNPISSNEEPDDEEADAEAKKSLWLHIKPEPELEADPDNCPVTEVAQVKRERRRRRAKLEVADERAEQQKSAASALAETEVKEEPLAAVGEQQLAIKQERQRIDSVNEDDEEEFELEVTGADMLHTSDDEEDEEEFCNEESDTDGIGDDDEEDEPGAEVESEEGKAQLTQTGQVEIVREYLQEPKASKQRRRRRNKQAETEVNPENRCDVCQRTFSRHCHLLRHKLSHLEKKPHNCPHCPKAFARSDHLKAHVQSLHGNKEHKCILCDAAFSRPDALERHKMSKHNGEGLDASSELKLQMNDHTCEYCSKRFSSKTYLRKHTLLHTEFLYACKSCDETFKERQLLRNHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRFCVKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFSQSNDLKAHIRRHTGERYKCPHCDAYFLQLYHMRNHCLSAHNMHIETKTGRLQRTGLLDEPNHSHLTTVVIPPSRFQQTTADSPTMATVTGQLPAAAAIAPPLIHSPVTYNTTSPVSVTVPVSDSAGFVGSTTSATATATTPFGAFNITPVVMAHLMYNHGGNSQQSNASGSETGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00803762;
90% Identity
iTF_00803762;
80% Identity
-