Hhis015689.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Hirtodrosophila histrioides
Gene Symbol
-
Assembly
GCA_037075165.1
Location
JBAMCL010000660.1:437211-442019[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.00024 0.016 15.9 0.3 1 23 281 303 281 303 0.98
2 13 0.081 5.4 7.9 0.8 1 11 309 319 309 323 0.86
3 13 4.9e-05 0.0033 18.0 0.6 1 23 530 552 530 552 0.97
4 13 4e-05 0.0027 18.3 1.5 1 23 558 580 558 580 0.99
5 13 9.6e-05 0.0064 17.1 4.7 1 23 586 608 586 608 0.99
6 13 7.1e-05 0.0047 17.5 4.5 1 23 614 636 614 636 0.98
7 13 1.9e-06 0.00012 22.5 2.8 1 23 657 679 657 679 0.99
8 13 8.7e-05 0.0058 17.2 0.4 1 23 685 707 685 707 0.99
9 13 0.00063 0.042 14.5 3.5 1 23 713 735 713 735 0.98
10 13 2.3e-05 0.0016 19.0 3.4 1 23 741 763 741 763 0.99
11 13 1.3e-05 0.00084 19.9 3.6 1 23 769 791 769 791 0.99
12 13 1.2e-06 8e-05 23.1 0.3 1 23 797 819 797 819 0.99
13 13 2.2e-07 1.5e-05 25.4 2.1 1 23 825 847 825 847 0.99

Sequence Information

Coding Sequence
ATGGAGGAAGTTTGTCGTGTTTGTATGACAATCTCCTGCAACCTTGTGGATATATTCGATGAGGAAACGCATTCGGTGGAGCAGCCCAGCCTGGCAGAGATGCTGAATGAGTGCGTCGCCTGCCAAATACACAGCACTGATCCACTTCCCAAGAAGATGTGCCTGGCCTGCGTTGACGCTgtccaaaatgcatttaaattaaagcagGAATGCCTGCAAAGCTCCTTTTCTATTATGGACGATGAACAAGTGTGTTGTGTTTGCAAGAGTGGCTCTGTGACCTTAGTCGATATATCCGCCAAAGGACATCAGCCGTTGGAGGATGCCAGCCTGGCAGAGATGCTGGATGAGTGCGTCGGTTATAAATCAGATCAAATTGATCCAATTCCAAAGCAGATATGCTCGTCTTGTGTGCTTGTTGTTCAAAATGCTTTCAGTTTCAAGCGCAGATGCGAAAAGAGCCATTTCCATCAGTTAGCAGTAAATGACATTAAAACTGAAATCAATGATACGGAAGGAGAAGAATATGTACTTCCGGATAATCACAAAGAGGAGATCGGAATGCTATATCATACGGAAAACAGTGAATATGTAGTGAAAAATGAACCTATGGAAAACGAAGAGTCTTTGCAGGAAGAAAACTTTGAACTCGAGGATAGTAAGTTGGTTGATCTCATTAAGATAGAGAAGGAGGAGTTTCATGGGCCATCAAGCAGTGAAGACGGATCGGAGGCGAATCTGTCTCCGATAGGTGAAGGTTTATTGGAAGAATCTGACCCTAGTCGCAACCTGCCTATGGACACCAGTGCTGATTCAATGTCATCTTCAAATAAGAAAAAGTTTGTCTGTGGCATTTGCGCAAGGAACTTTTCCCGCTACGATCTTCTCGAAACACACAACCGCATTCATTTAGGCGAACGCCCGTACAAGTGTCCGCATTGCCCAAAGGATTTTGAACCGCATTCGGAGGAGCAGCCCAGCCTGGCAGAGATGCTGAACGAGTGCGTCGCCTGTCAAATACACCGCACTGATCCACTTCCCAAGAAGATGTGCCTGTCCTGCGTTGACGCAgtccaaaatgcatttaatttaaagcgGCAGTGCCAGCAGAGCTCCAGCTCAGTAAAGGACGTGCAACAAGTGTGTTGTGTTTGCAAGAGTGGCTCCGTGACCTTAGTCGATATATTCGCCAAGCGACATCAGTCGATGAAGGATGCCAGCCTGGCGGAGATGCTGAATACGGAAGGAGAAGAATATGTACTTCCGGATAATCACAAAGAGGAGAACGGAATGGTAGATCAGACAGAAACCAGTGAACATGTGGTAAAAAATGAAGCCATAGAAAACGAAGAGCCGTTTGAAGATGAAGCGTATGAACGTGACGATAGGGAGTTTTTTGATCTCATTAAGATCGAGGAGGAAGAGATTCATGAGCCATCAAGCACTGAGGACGGATCGGAGGCGAATCTGTCTCCGATAGGTCACAGTATATTGGAAGAATCTGACCATAAGATCAGCAGTCATGCGAATCACAAGTTGCCCATGGACACCACTGCGGATTCAATGTCATCTTCAAATAAGAAAAAGTTTGACTGTGGCACTTGCGGAAGGAACTTTACCCGCTATGATCTTCTCGAAACACACAACCGCATTCATTTAGGCGAACGCCCGTACAAGTGTCCGCATTGCCCAAAGGATTTTATAACCCGTAAAAGTCAATTGGCTCACATCAGCACTCATACTAAAGAACGTTCATACAAGTGCTGTCACTGCCCAAAAGAATTTACGAACCGTCAACTTCTGGTTGAACACACGCGTATTCATTCCGGGAAACGTACTTTCCAGTGTCCACATTGCCCACAAACATTTGCCTGTAATTCAAATCTCCGGCAACATATACGCTTTCATGCTGAACGTCCCGTCAAGATGTCACAAGGCAAAGGTAGCTCCAATACCGTGGAACGTCCATTCCAGTGTCCGCATTGCCCACACAAATCTGCCAATAATTCAAATCTTCAGAAACATATTCGCGTTCATATTGGGGATCGTCCATTCAAGTGCTCCGAATGCCCAAAAGAATTTGCTATCCGTCAACTTCTGGAAAATCACAAGCGAATACATACCGGGGAACGTCCATACGACTGCCCACATTGCCCACAAAAATTTGTGTGTAACACAAATCTCCGCAGCCATCTACGCGTTCATAGTAGTGAACGTCCATACAAATGCTCAGAATGCCCGAAGGAATTTGCTCACAGCCAATCTCTAGTACATCACAAGCGAATTCATACTGGCGACCGTCCATACGAGTGTCCGCATTGCCCACAAAGATTTGCCTGTAATTCGAATCTCCGCACTCATATACGCACTCACACGGGCGAACGTCCCTTCAAGTGTCCCCAGTGTCCGAAGTCTTTTATCCAGGCCAATGTCCTCCAAACGCATATACGCTCCCATTCCGATGAACGTTCCTTCAAGTGTTCTAAATGTCCGAAAACATTTAAACAGAGCGTTGGACTCCGGAATCACATTCGCCGTCATCCCGACCATGGTCCTAGCAAGTAA
Protein Sequence
MEEVCRVCMTISCNLVDIFDEETHSVEQPSLAEMLNECVACQIHSTDPLPKKMCLACVDAVQNAFKLKQECLQSSFSIMDDEQVCCVCKSGSVTLVDISAKGHQPLEDASLAEMLDECVGYKSDQIDPIPKQICSSCVLVVQNAFSFKRRCEKSHFHQLAVNDIKTEINDTEGEEYVLPDNHKEEIGMLYHTENSEYVVKNEPMENEESLQEENFELEDSKLVDLIKIEKEEFHGPSSSEDGSEANLSPIGEGLLEESDPSRNLPMDTSADSMSSSNKKKFVCGICARNFSRYDLLETHNRIHLGERPYKCPHCPKDFEPHSEEQPSLAEMLNECVACQIHRTDPLPKKMCLSCVDAVQNAFNLKRQCQQSSSSVKDVQQVCCVCKSGSVTLVDIFAKRHQSMKDASLAEMLNTEGEEYVLPDNHKEENGMVDQTETSEHVVKNEAIENEEPFEDEAYERDDREFFDLIKIEEEEIHEPSSTEDGSEANLSPIGHSILEESDHKISSHANHKLPMDTTADSMSSSNKKKFDCGTCGRNFTRYDLLETHNRIHLGERPYKCPHCPKDFITRKSQLAHISTHTKERSYKCCHCPKEFTNRQLLVEHTRIHSGKRTFQCPHCPQTFACNSNLRQHIRFHAERPVKMSQGKGSSNTVERPFQCPHCPHKSANNSNLQKHIRVHIGDRPFKCSECPKEFAIRQLLENHKRIHTGERPYDCPHCPQKFVCNTNLRSHLRVHSSERPYKCSECPKEFAHSQSLVHHKRIHTGDRPYECPHCPQRFACNSNLRTHIRTHTGERPFKCPQCPKSFIQANVLQTHIRSHSDERSFKCSKCPKTFKQSVGLRNHIRRHPDHGPSK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-