Hdun000469.1
Basic Information
- Insect
- Hirtodrosophila duncani
- Gene Symbol
- Znf574
- Assembly
- GCA_037043425.1
- Location
- JBAMBM010000030.1:159661-165590[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 1 64 4.4 1.9 2 23 502 524 501 524 0.94 2 10 0.094 5.9 7.7 0.1 6 23 534 551 534 551 0.98 3 10 0.00025 0.016 15.8 3.2 1 23 557 579 557 579 0.98 4 10 0.14 8.7 7.2 0.6 1 23 588 611 588 611 0.84 5 10 0.00039 0.024 15.2 2.8 1 23 619 642 619 642 0.97 6 10 0.25 16 6.4 0.4 3 23 650 671 648 671 0.92 7 10 0.79 50 4.8 0.2 2 23 683 705 682 705 0.92 8 10 0.0025 0.15 12.7 4.1 1 23 712 735 712 735 0.93 9 10 8.5e-07 5.3e-05 23.6 1.4 1 23 741 763 741 763 0.98 10 10 0.065 4 8.2 3.3 1 23 769 792 769 792 0.97
Sequence Information
- Coding Sequence
- ATGAACCGAGTGGATACGTTCGCACCCAAGAAGTCAAAACTGCAGAAAAGTAATAGAGCCCTTGCTACCGAGCTAGGTAAGCTACTGGATGAAATTATCCACACCACGGTGAAGAAAAAATGCCTCGGAAGCCAGTGCAGAAGCAGAAGGCCTCTGCAGACACGCGGAATACCCAAGCCAGCAGAGAAACTGCAGCGGGAGCAGCATATATCAAAAAGGGAAGGAGACAGCCGAAAAAAGGAAGCCACCAACAAGCCGGACGCACTTGTTATAAGAGCAACTGGGAAGGCAACCTATAGTGATATCCATGCCATGATCACCCACCACGAGGATGACAAACTAAAGAGCGTCGGTGAAAACGTCGCCACTCTGCCGAACTACCAAAGGGAGTTCGAGCTCGAGCTAAATGGATCCGCACTTGACTGCACCCAGAAGCTCAAAAAGAACACTGTGGAGGTCCTTAGAGAAAGCGCTGATGAACTTGCTAGTTGCTTACTCTGTTTGGATGAGTATCCAATGGTGGCCCAAGGGGAATATATCCTACTTCAGTCTCAAAAGGGAGTCCAACTAGAGGTGGCGAAGTTAATAAGCAAGCATATGCCAGTACGGCTCACGAATGCACTAAATGAAAGAATATGCGCGCACTgttggaaaattgttttcgattttcataTGTTACACGAGTTTGTCACTGCAGCGCAGAACTCGTTGCAGGAGACAAAAGTTCTGCTAATAGAAGATGATCCACTGACACAGGGAAATATCAGCGAAGCTCGAGCAAGAAAACCGAATCTGAGCGCACCTGTGGAAGCCTCTCAAGACCAATCCGAAGAGAATGAGCGGAATTTCTTCTATCCCGAGGTCAAGATAGAGGAGCATGAGCTGGATCAGTTGCCGCAAATTGAGATTCTTGAAAGATCGACTAACGTGCAAGCTCTTGAACCAGAAAAGGAACGCACGACCACCAGACGTTTGAGAAAGCGTGTCAAAGCAGAGGTTGAAACTATCAATTCCAGTGTGGAACTGTTCAAGGATGGCAGCCAACAAACTGTTACTTCCGCAGATCCAGCCGCAAGTGTTACGCCTAAAAAACGACGTGGACGTCCGCGGAAAGTGGAAACCTCTACGGTCACTGATCTGCCGGAGGCTCCTTCACTTCCCACTGTCcctaataataaaaatgttgaattaaaATCAGAAGAAGTTCCAGATTTCGGTAGCGATGATGATCCAGACTTTACCGCCGACATTGAAGCCTTGCCTAACAGCAGCAGTGACAGCAGTTCCGATAGCGATGAGGACTCGGACTTTGAGCTGGACAAGCCAGACATGGCTGAGTTTGTTGTCATACCCAAGCGAACTGTTGTGCGGCCGAAGAAGTACAAAAAGGGGCCCAAGCCGGCGGAACCGAAGGTACGCATGTCTAAGGAAATGCTGGAGCAACGCAAGAAACAGCAAGAGGAATACGATGAAGTCATTGCAAAGTTCTTCAGCAACGTGCTGCCATGCCCCATCTGCAATCTGCTGGTGCATAACTTTACAGAAATGCAGCGGCATCACCGTCTTACCCATCAAGTGGATCCCGGCTACATGATGTGCTGCGGGCGAAAGTTCACACAACGCAAAGTGCTGGCCGAGCATGTCTTAGTCCACTGGAATCCAGATCACTTCAAGTGCCTGACGTGCGCAAAGTCATTCCAAAACTCCCGCCATTTGGAGTCGCATCAGCAGGTGCACGTGGATCCTGCCATTAAGCTGACGTTCGAATGTGACATATGCTCGAAGGTCTTCCTAAGCAAAACAGCCATCGAGTACCACAAACTCAACAAGCATGTGCCCAAGTCCGAGTTCAAGTTCACATGCACTGAGTGCAATAAAAAATTCCTCACGGAGCGTAAGCTGAAGAACCACATGAACTCCATGCACGATCCGGAGAGCACCATTATCTGCGACAAGTGTGGCAAACAGATGCGCACCAAAATCATTCTCAAGAAGCACCAGGAGCTCATGCATTCGGACAAGCCACGTCCCGAGCCAGAGTTGAAGCAGTGCCAGATATGCGGAGCTTGGCTGAAGGGCATGACGGGTCTAAAGCAGCACATGAAAAGTATACATGTGGAGAGCGCCGGCGAGCATCGTTGCCACATCTGCAGCAAGGTGTCACCCAATGCCCGCGCCCTGCGTCGACATATCTACCACAACCACGAATGCGAGCGCAAATTCAAGTGTACCATGTGTGATAAGGCCTTCAAGCGACCGCAGGAACTCAAGGAGCACACGTCTACGCATACTGGAGAAGTGCTTTACACCTGCCCCAACTGCCCGATGACATTCTTCTGCAGTGCTAACATGTATAAGCATCGCCAGCGTTTGCATCGCGCCCAATACGAGGCGGACAAGAATCAGCCGCGGCCGCCTAACATTTTGAAGGCAGCTGTCGGCGCCACTGCCGCCATGAAGATCAAACTTATGCAGACCCCAAACACTTCCATCATTGAATCTGACTTGAAGCATTTCTAG
- Protein Sequence
- MNRVDTFAPKKSKLQKSNRALATELGKLLDEIIHTTVKKKCLGSQCRSRRPLQTRGIPKPAEKLQREQHISKREGDSRKKEATNKPDALVIRATGKATYSDIHAMITHHEDDKLKSVGENVATLPNYQREFELELNGSALDCTQKLKKNTVEVLRESADELASCLLCLDEYPMVAQGEYILLQSQKGVQLEVAKLISKHMPVRLTNALNERICAHCWKIVFDFHMLHEFVTAAQNSLQETKVLLIEDDPLTQGNISEARARKPNLSAPVEASQDQSEENERNFFYPEVKIEEHELDQLPQIEILERSTNVQALEPEKERTTTRRLRKRVKAEVETINSSVELFKDGSQQTVTSADPAASVTPKKRRGRPRKVETSTVTDLPEAPSLPTVPNNKNVELKSEEVPDFGSDDDPDFTADIEALPNSSSDSSSDSDEDSDFELDKPDMAEFVVIPKRTVVRPKKYKKGPKPAEPKVRMSKEMLEQRKKQQEEYDEVIAKFFSNVLPCPICNLLVHNFTEMQRHHRLTHQVDPGYMMCCGRKFTQRKVLAEHVLVHWNPDHFKCLTCAKSFQNSRHLESHQQVHVDPAIKLTFECDICSKVFLSKTAIEYHKLNKHVPKSEFKFTCTECNKKFLTERKLKNHMNSMHDPESTIICDKCGKQMRTKIILKKHQELMHSDKPRPEPELKQCQICGAWLKGMTGLKQHMKSIHVESAGEHRCHICSKVSPNARALRRHIYHNHECERKFKCTMCDKAFKRPQELKEHTSTHTGEVLYTCPNCPMTFFCSANMYKHRQRLHRAQYEADKNQPRPPNILKAAVGATAAMKIKLMQTPNTSIIESDLKHF
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -