Basic Information

Insect: Hirtodrosophila duncani
Gene Symbol: L
Assembly: GCA_037043425.1
Location: JBAMBM010000030.1:3800765-3807214[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 1.2e-05 0.00078 19.9 2.9 1 23 131 153 131 153 0.98

2 16 0.43 27 5.6 6.2 1 23 159 181 159 181 0.97

3 16 2.1e-07 1.3e-05 25.5 3.2 1 23 187 209 187 209 0.99

4 16 1.5e-05 0.00095 19.6 0.4 1 23 215 237 215 237 0.99

5 16 0.046 2.9 8.7 0.1 2 23 316 340 315 340 0.93

6 16 0.00057 0.036 14.7 0.4 2 23 362 384 361 384 0.95

7 16 0.033 2.1 9.1 0.7 1 23 470 492 470 492 0.97

8 16 0.02 1.2 9.8 0.1 2 23 500 521 499 521 0.94

9 16 0.00043 0.027 15.1 0.1 1 23 529 553 529 553 0.93

10 16 0.0031 0.19 12.4 1.1 1 23 652 675 652 675 0.97

11 16 0.0061 0.38 11.5 1.2 2 23 856 878 855 878 0.96

12 16 0.14 8.8 7.2 0.1 1 23 884 906 884 906 0.92

13 16 6 3.7e+02 2.0 0.2 2 23 914 935 914 935 0.92

14 16 0.9 57 4.6 0.5 2 23 1037 1058 1037 1058 0.94

15 16 0.024 1.5 9.6 0.0 1 23 1068 1090 1068 1090 0.96

16 16 0.001 0.064 13.9 2.0 1 23 1097 1119 1097 1119 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	1.2e-05	0.00078	19.9	2.9	1	23	131	153	131	153	0.98
2	16	0.43	27	5.6	6.2	1	23	159	181	159	181	0.97
3	16	2.1e-07	1.3e-05	25.5	3.2	1	23	187	209	187	209	0.99
4	16	1.5e-05	0.00095	19.6	0.4	1	23	215	237	215	237	0.99
5	16	0.046	2.9	8.7	0.1	2	23	316	340	315	340	0.93
6	16	0.00057	0.036	14.7	0.4	2	23	362	384	361	384	0.95
7	16	0.033	2.1	9.1	0.7	1	23	470	492	470	492	0.97
8	16	0.02	1.2	9.8	0.1	2	23	500	521	499	521	0.94
9	16	0.00043	0.027	15.1	0.1	1	23	529	553	529	553	0.93
10	16	0.0031	0.19	12.4	1.1	1	23	652	675	652	675	0.97
11	16	0.0061	0.38	11.5	1.2	2	23	856	878	855	878	0.96
12	16	0.14	8.8	7.2	0.1	1	23	884	906	884	906	0.92
13	16	6	3.7e+02	2.0	0.2	2	23	914	935	914	935	0.92
14	16	0.9	57	4.6	0.5	2	23	1037	1058	1037	1058	0.94
15	16	0.024	1.5	9.6	0.0	1	23	1068	1090	1068	1090	0.96
16	16	0.001	0.064	13.9	2.0	1	23	1097	1119	1097	1119	0.98

Sequence Information

Coding Sequence: ATGTATAGCACGCACACCTCCTCCAGCTACTCGCCAAGCATTTCGGATGGCACCCTGACGCCCAACTCGCTGCACCATCATCAGCCTCATCATCACCAGCAGTCACAGCTGGCCGGCGGCACACACGATGAGCCCAGCGCCAGTGCCGAGATCAAGGCAAATGGCTCTGGcgaggagcaacagcaaacacaaaccaaGTCCAAGCGCCCATCGCACTTACATCCGcaccatcatcaccatcattatcatcaccAGCAGGCTCTGAAAATTGCCAACAAGTTGAGAAAAATCAATAAGGAAGCCAAGCTGGGAGCCGCTGGAGCTGCTGGAGCAGCCGCAAAGTTTGATAAGTTGACAGGCGAAGGCATTAAGAGCCGCGGCGACGGTTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGTTACTTGAAACATCACGTGCAGAGTCATGCCGAACATTTGCCATTCAAATGTGAATACTGCGCCAAGCTGTTCAAGCACAAGCGTTCCCGAGATCGCCATAAGAAGCTGCATACCAACGAGCGAAACTACAAGTGTCCGCACTGTGAGGCGGCCTTTTCGAGAAGCGATCACCTGAAGATCCACATGAAGACACACGATATTCAGAAACCCTTCCAGTGCAGCATGTGCAATCGTGGCTATAACACCGCCGCCGCTCTAACCTCCCACATGCAGAAGCACAAGAAGAACGCCGCCATTTTGGCAGCTGGTGGTAATCCCAATGCCTTGAACTACAGTCCACGTTCGACCGGTTCCGCGTCGGTATCCAGCAATGGCAGCCTGAACAAGCGCCGTTACGCCTTGGCCCTTGCCTCCGACAGCAGTCCGAGCCGCTTGGAGTTTCCCAGCAAGCGAGCCAGAAGTCATTTGGGCAGCACGCCAACGCCAACTGCTACTCCCTCAACTCCATTGCTGCGATGCAGCTATTGTCCCAAGTTGACAGAGTTCAGCAGTCTGGAGCAACTGAATGCCCATCTGGCCAGTGTTCATGAGCAGCCCAAGACACCGGCGTCACTGCCAGCTTCAGATGGCGGATCGGAAGCCTTTCAGCTGAGCTGTGAATATTGCACTATGAAGTTCAGCAACATTGCCGGTCTGTTCCAGCATATGAGAGCCACGCATCTGGATCGCCTGAGCAGCCCCAATTCCTACTACGAGCATTTTAATCGCCTGGCCACAGCCGGCACCTTTAGTCCCCGTTTGGCGCTGGATTTGCCAAAAATGAAACAGGATTTTCCCAGCCCAGAGAGACATCCCCAGCCGCCTGCAGAGAAACCAGGAGATGATCTGCCCACTGATCTAAGCAGCAATAAGCGGCGCTGCTTGACGCCTCATGCTCATACaccggctccagctccagcgccTCCACCGGGCATTTTCTTCTGCAATCAATGCAATGCGGGGCTGCCAGACTTCGAGAGCTTCCGCAACCATCTGAAGACGCACATAGCCGAGGGCATGCAGCTGATCTGTGCTCATTGCGGCCTCAGCCTGCCCGATCAGACCGAGTACGAGCGCCATGTGGTGTCCcatttcttgatcagcagctgCGAGTTCAACTGCAGCTCCAACTGCGGCCAGTCGTTTGCCAAGGCGGATGAACTGCAGCAGCATCTGCTTGCCGAGCATGTGGTAACCCTGCTGAAGTGTGCTCTCTGCTCCGAGCTGTGCGAGACGCGCATGGCCATGCAGCTCCATCTGGCCTGCGCTCACACCCAAGAGACGAAACTACTTCGATGCAGCGCCTGCATGGAGCTCTTCCGCACCGATGCGGAATTCCATGTGCACGTGAAGACGCGGCATCAGTTGGGCAATCAGTTGGCCAACGTTAGCCCAGCCAATCCGCTGCAGTGCATGTTCTGTCGCGCCGTTTGCTCTTCGGAGCTGGAGATGCACTTCCATTTGGCCGCTCATGCGCGGCAATTCCGTTGCCCCTCCTGCCCGGAGACGTTCCACGTGGAATTTCTACTGGACAGGCACATGCAGAGTCAGCACGCTGGCGTTGGTCTAGCCAAGGACAAGGAGCAGAGCTCTCAGACCAGCCGTTCTCGCTCGCCGCCCAACATGGGCAGTCTCTATGTAAATGCGCTGCTGCCTCCAttggctgctgccgctgcagctgccgctgccgccaccaacaacaacagcagcatcattgACTACAATGTGGCTTTCAAGGGTCTGTTCGGAGCTTCGCCGGCAGCGGTCAATCAGCCCCAGGCCGCCAGCAAATTTTACAGTCCACTGCAGGTGGATACGAGCACATTGAAGCCGCAGAGCTCACCGCATCCCGCTTTAATGTATGGCCTGAGTCAACGCTATCTGATGGAAATGTATGCGGCAAAATCGACTTCACCCTCCGCCAGTGCCGCAAGTGAGACACCCACACCCGGTAACGCCATGCCTCCAGCTCCACCGCCGCCGGCGCCAGCGACCTATAGCTGTGGCATGTGCGAACGTCAGGATTTGCGCAGCGAGGCGGAGCTTCATTCGCATCGCAAGCTGGCCCACAATCTCAAGACCGGCGTGAGTCTGCGTTGCGCCTATTGTGCCGGCAACTTCAAGTCGCGGGCGGAACTGGAGCAGCACATGAAGAGCTGCCACAACTCAACCGGCAAACACAAGTGTCTCATCTGCGATGAGATCTTTCCATCGCCAGCCATACTGGCCGAGCACAAACTACAGCACTCGAAGGTGGGTCAGCTGGGCAAGTGTTCGCATTGCGCCCAGCAGCTGGCGGATGTGGCTGCCTTCAGGGCCCACCTGGGAGAGCATGGCAGCGATGGCAGTCTGCCCTTGGCGTGCATTTGCTGCCGCCAGACGCTGCACTCCGAATTCGAGCTGAGTTTGCATGCCAAATTCCATACCAAATCCTCGTCGAGTGGCAGCCTGCAGGAGCCAGTTTGCGCTCTGTGCCTCGAACCGCTACCAGTTGCTGCCGACGGTTCAActgccacacccacacccgcCAAGTTGTGCGAGAAGTGCTGCCGCAAGCATAATCTCAATCTGAACGGAAAGCGTGGTGGCAAACCAGAGCCTCCTGTGACTGCGCCAGTGCCACCCTATCTGGAGAACCGCTGTAATCTGTGCAAGATGATCTTGCCGCATGCACAGAAGCTGCAGGAACATCTAGTGGAGCACACATTTGCCGGCACCGAGCAGCGAGGGTTCAACTGCTACATCTGTTCAGCTGTCTTCACCGCTCCCAGTGGTCTGCTTGGCCACATGGCGGAACACGGTGCCCATGCGCGTCCTTACGATTGCAATATGTGTGCTGAGAAATTTTACTTCCGCGCCGAATTAGAGCATCACCAGAGATCGCACGAATTGAGACCAACCCGTGGTCCGGGGCCTAAGCTGGAGCCTCCTAGAACGAGATCACCCAGTGCGAGTAGAAGCAGTCCGACCACCGTCAAACAAGAGCTCTATGAAACGGAAACTGTGGCCGCCTCGCCAGTGGAACCAGATCAGACAGACGAAACAGAGTCTATTCAGGCCCAGGATGAGGAAGAATACATTGAAGTTGAACAAGTGCCGCAGGAGATGCGTTCCGGTGAGATGAACAGTGCGAGTCAGACGGAACGTGCCAGTAGCACTGCCTAA
Protein Sequence: MYSTHTSSSYSPSISDGTLTPNSLHHHQPHHHQQSQLAGGTHDEPSASAEIKANGSGEEQQQTQTKSKRPSHLHPHHHHHHYHHQQALKIANKLRKINKEAKLGAAGAAGAAAKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASVSSNGSLNKRRYALALASDSSPSRLEFPSKRARSHLGSTPTPTATPSTPLLRCSYCPKLTEFSSLEQLNAHLASVHEQPKTPASLPASDGGSEAFQLSCEYCTMKFSNIAGLFQHMRATHLDRLSSPNSYYEHFNRLATAGTFSPRLALDLPKMKQDFPSPERHPQPPAEKPGDDLPTDLSSNKRRCLTPHAHTPAPAPAPPPGIFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICAHCGLSLPDQTEYERHVVSHFLISSCEFNCSSNCGQSFAKADELQQHLLAEHVVTLLKCALCSELCETRMAMQLHLACAHTQETKLLRCSACMELFRTDAEFHVHVKTRHQLGNQLANVSPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHAGVGLAKDKEQSSQTSRSRSPPNMGSLYVNALLPPLAAAAAAAAAATNNNSSIIDYNVAFKGLFGASPAAVNQPQAASKFYSPLQVDTSTLKPQSSPHPALMYGLSQRYLMEMYAAKSTSPSASAASETPTPGNAMPPAPPPPAPATYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQLGKCSHCAQQLADVAAFRAHLGEHGSDGSLPLACICCRQTLHSEFELSLHAKFHTKSSSSGSLQEPVCALCLEPLPVAADGSTATPTPAKLCEKCCRKHNLNLNGKRGGKPEPPVTAPVPPYLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPSGLLGHMAEHGAHARPYDCNMCAEKFYFRAELEHHQRSHELRPTRGPGPKLEPPRTRSPSASRSSPTTVKQELYETETVAASPVEPDQTDETESIQAQDEEEYIEVEQVPQEMRSGEMNSASQTERASSTA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -