Basic Information

Insect: Hirtodrosophila duncani
Gene Symbol: ken1
Assembly: GCA_037043425.1
Location: JBAMBM010000601.1:28527-30920[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.082 5.1 7.9 5.9 3 23 267 287 265 287 0.96

2 12 0.00056 0.035 14.7 0.8 1 23 293 318 293 318 0.95

3 12 0.02 1.2 9.8 2.0 1 23 325 350 325 350 0.95

4 12 6.8e-05 0.0043 17.6 2.5 1 23 359 381 359 381 0.97

5 12 0.00052 0.033 14.8 0.1 3 23 390 410 388 410 0.98

6 12 0.0089 0.56 10.9 0.5 1 23 416 438 416 438 0.97

7 12 0.034 2.1 9.1 1.3 1 23 444 467 444 467 0.97

8 12 0.012 0.72 10.6 2.8 1 23 473 495 473 495 0.96

9 12 0.001 0.064 13.9 0.3 3 23 503 523 502 523 0.97

10 12 8.5e-06 0.00053 20.4 1.7 1 23 611 634 611 634 0.96

11 12 0.005 0.31 11.7 3.6 1 23 640 662 640 662 0.94

12 12 7.8e-06 0.00049 20.6 2.0 1 23 668 690 668 690 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.082	5.1	7.9	5.9	3	23	267	287	265	287	0.96
2	12	0.00056	0.035	14.7	0.8	1	23	293	318	293	318	0.95
3	12	0.02	1.2	9.8	2.0	1	23	325	350	325	350	0.95
4	12	6.8e-05	0.0043	17.6	2.5	1	23	359	381	359	381	0.97
5	12	0.00052	0.033	14.8	0.1	3	23	390	410	388	410	0.98
6	12	0.0089	0.56	10.9	0.5	1	23	416	438	416	438	0.97
7	12	0.034	2.1	9.1	1.3	1	23	444	467	444	467	0.97
8	12	0.012	0.72	10.6	2.8	1	23	473	495	473	495	0.96
9	12	0.001	0.064	13.9	0.3	3	23	503	523	502	523	0.97
10	12	8.5e-06	0.00053	20.4	1.7	1	23	611	634	611	634	0.96
11	12	0.005	0.31	11.7	3.6	1	23	640	662	640	662	0.94
12	12	7.8e-06	0.00049	20.6	2.0	1	23	668	690	668	690	0.99

Sequence Information

Coding Sequence: ATGAATGAGGGGAGTCAATACTCCATACACTCAGTATGCCGAACTTGCTTGGCCGGCTTGGAGAGCGATGCGTCCTACGACCTATTTATGGTCCCGGGACTGGCCAAGAAGCTGTGCGTGTGTACGTCATTGTCCGTGGAAAAACAGGACGGCTTTCCCAAGAATCTCTGCACCAAATGCTATACGCGGCTTAATGACTTGCATGACTTCCAGATGCTGTGTGTGGACTCTGTGCAAAAGTTCCAAGATTTGGTTGCCAGCAATGTTTTTACATGCCAGACAAACTTCGATGAGTTGAATGTGCCTGGAAATGAGGATAATCTGGCCATCGAGGAGGATGACCGCATTAACTTTGATCCGCTGTTGAATTCCAAAATAGAAATCATTGAGAATGAGGAGGACGTCTTCAAGATGCTGGAGCATGTGGAGAAGGAAGCCGAGGAGGTGGAGAAGGAGGTCAAGCAAGATGATGCGCCATCGCCGTCAGAGGCCACGCTCGGGTTTAACGACGATTCCTCATTTGAAAGCGATAACGACAATGACAGAGACGTGGACTTTGAACTCAACAGCAGTAGCGATGATGACATTCCCCTTGCCCAACGGACTCGAATTCAACGCAATTCCAAAACAGCATCCAAGAAGAAAaccagtagcagcaacaagagcaaaaaAGACGAAGACTTTTTGTCCGTGTccgacgatgatgatggcgatgatgatggcgaGTATGGATCAAAGGGAAAGACAAAAAGCAAACGGACACCTGCTGGAGAGAAGCATTTACATACCCTAATCGATTGCCACATCTGTCACCAGAAATTCAAGAAGGCAATCCGCTATGAGGAGCACATGAAGCATCACAACGATCTGCTACCCTTCCAGTGCAAGGTCGAAAGCTGCAAAAAGGGCTTCACCACTGCCAATGGCCTGCGCGTTCACATGGAGCATGCTCATACAGATTCCTCCGAGATGCACACCTGTACCGTAGAAGGATGCGGCAGAACCTTCGCCCGCATTGGTCTGTTGCATTTCCACATGAAGAGGATGCACAAGATGGAAACGCCACTAAGGGAGTTTCCCTGCACGGAGTGTGACAAGGTCTTCCGCTGTCCTACAGCTCTCAAAAAGCACATGTACAAGCACACAGGCGAGGAGTTGCCTTTTGGCTGTGAGATTTGCGGTAAACGCTTCCCTATCAACAGTGTGCTTCGGGATCATCTTCTGCGACATGCGGGCGTAAAGAATCACGTCTGTCCTTACTGTGGAGTAGGCAAGACGACGCGGCAGGAGTGGAACAAACACATCTTGACTCACACTAAAGAGAAGAAATACGAGTGTCGTCAGTGCGATCATGCGTCGCACAACAAGCAGGCCTTGGCCAATCACGTCAAGGTAGTGCACATGAAGATCAAAGACTTTGCCTGCCAATATTGCGGGAAAACCTTTGGAAAGTCGTTCGCCTGCAAGATCCACGAACGCAGCCACACGGGCGAAAAGAACGTCGATTGTAAGATATGTGGTAAAGTCTTCCTCTACGAAAAGGGTTTGACCAAGCATTTAAAGGCACACGAAAAGCGAGACCTGCCAAAATCAACAAAGGCTAGTGTTCAGAGTGATGatgcggcagcaacaacaactgcaagtGATCAACCACTTGGGCCATCAACATCTGGTGTCATCAAGCCGCCTCCAAAGCCAAAGGGCACACACACTGGACGCGTGGAGGTTGTGGATATCTCGCAGCTGGCAGGCACCGTTGTCAATCCTATACCATCTGTGAACCTGCCCTCATGGACGCCACAGGTGAACTTCACGAAAAAAGAGGGCCAGCATATGTGCCCAGACTGCGGCAGAGGCTTCAACCACGCCAGCAATATGAAGCTCCATTACAAGATCATTCACCAGAAGGTCAAGGACTTTGCTTGCCGTTTTTGTCCCAAGCGCTTTGCCAAGAAACAATATCTGCGGCATCATGAGTACATCCACACCGGCGAAAAGCCATATGAGTGCAAAATCTGTGGCAGGCATTTCCGCCAGGAGCAGGTGCTGAAAACGCATTTAAGGGTCCACGATAAGCCACCGAAGCCaccagccaagccaaaagaGTCGGCGGGTCCAAAAACCGAAAGAAAACGCGATATGCCCAAGAATTTTGAGCAGTACCAGGATCCGGCGGCAGAGCGAGCTGCTGCGACAGCTGAACTGCTTGCATTTCAGATTGAGGAGAGTGAGGCCAAGCGGAAGGCCGAATTGGAACTACGCAAGATCCAGGAGGCTGCCTATGAGCAGTTACACAAGCTGCAAAAGCAACAGGGCACCTACGAGGGCTTTTATGCCCAGAAAGCGGAGGTAGACGGCACCAATGTGGATTCTCTCAAACTGGATCACGTGTAA
Protein Sequence: MNEGSQYSIHSVCRTCLAGLESDASYDLFMVPGLAKKLCVCTSLSVEKQDGFPKNLCTKCYTRLNDLHDFQMLCVDSVQKFQDLVASNVFTCQTNFDELNVPGNEDNLAIEEDDRINFDPLLNSKIEIIENEEDVFKMLEHVEKEAEEVEKEVKQDDAPSPSEATLGFNDDSSFESDNDNDRDVDFELNSSSDDDIPLAQRTRIQRNSKTASKKKTSSSNKSKKDEDFLSVSDDDDGDDDGEYGSKGKTKSKRTPAGEKHLHTLIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCKVESCKKGFTTANGLRVHMEHAHTDSSEMHTCTVEGCGRTFARIGLLHFHMKRMHKMETPLREFPCTECDKVFRCPTALKKHMYKHTGEELPFGCEICGKRFPINSVLRDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTKEKKYECRQCDHASHNKQALANHVKVVHMKIKDFACQYCGKTFGKSFACKIHERSHTGEKNVDCKICGKVFLYEKGLTKHLKAHEKRDLPKSTKASVQSDDAAATTTASDQPLGPSTSGVIKPPPKPKGTHTGRVEVVDISQLAGTVVNPIPSVNLPSWTPQVNFTKKEGQHMCPDCGRGFNHASNMKLHYKIIHQKVKDFACRFCPKRFAKKQYLRHHEYIHTGEKPYECKICGRHFRQEQVLKTHLRVHDKPPKPPAKPKESAGPKTERKRDMPKNFEQYQDPAAERAAATAELLAFQIEESEAKRKAELELRKIQEAAYEQLHKLQKQQGTYEGFYAQKAEVDGTNVDSLKLDHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -