Basic Information

Insect: Hirtodrosophila duncani
Gene Symbol: ZNF526
Assembly: GCA_037043425.1
Location: JBAMBM010000098.1:3087459-3089528[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.12 7.3 7.4 0.2 1 21 323 343 323 344 0.95

2 10 3.2e-06 0.0002 21.8 0.2 1 23 352 376 352 376 0.91

3 10 0.071 4.5 8.1 1.0 1 23 379 402 379 402 0.92

4 10 6.5e-07 4e-05 24.0 2.4 1 23 408 430 408 430 0.98

5 10 9.6e-09 6e-07 29.7 0.8 1 23 436 458 436 458 0.98

6 10 8.5e-05 0.0053 17.3 1.6 1 23 464 486 464 486 0.99

7 10 6.9e-05 0.0043 17.6 2.4 1 23 492 514 492 514 0.98

8 10 0.0013 0.081 13.6 0.3 1 23 520 542 520 542 0.98

9 10 0.00014 0.0089 16.6 3.7 1 23 548 570 548 570 0.98

10 10 0.053 3.3 8.5 0.0 1 23 576 598 576 598 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.12	7.3	7.4	0.2	1	21	323	343	323	344	0.95
2	10	3.2e-06	0.0002	21.8	0.2	1	23	352	376	352	376	0.91
3	10	0.071	4.5	8.1	1.0	1	23	379	402	379	402	0.92
4	10	6.5e-07	4e-05	24.0	2.4	1	23	408	430	408	430	0.98
5	10	9.6e-09	6e-07	29.7	0.8	1	23	436	458	436	458	0.98
6	10	8.5e-05	0.0053	17.3	1.6	1	23	464	486	464	486	0.99
7	10	6.9e-05	0.0043	17.6	2.4	1	23	492	514	492	514	0.98
8	10	0.0013	0.081	13.6	0.3	1	23	520	542	520	542	0.98
9	10	0.00014	0.0089	16.6	3.7	1	23	548	570	548	570	0.98
10	10	0.053	3.3	8.5	0.0	1	23	576	598	576	598	0.96

Sequence Information

Coding Sequence: ATGGATGTGTCGAAGGTTTGCCGCACTTGTTTAAATGTTACAGGTCCCTTCATGACCATTTGGGGAGCGGGCAGCTGTGTGGCGGACATGCTGCGGGgcttcacaaaaacaaatCCGCGTCCTGGAGACAATCTACCACAGAATGTTTGCATACCCTGCATCAGCGAAATAAGTCGCTGTCATGAATTCAAGTCAAAAATCGAAAGCACCTGCAGAACGTTACACCAATTGCTGTCTTTACCCGAGGAGCTATTAGACGATGTTGCTGTGCCAATTAAACCAGAGGTGGTCACTGCCGACATAGCCGTGCAGACCtgtgcagcaggagcagcaacaacagccacagttGAAGTACAAACGGATGTGTATACAAACAATGCCGCCAGAGATGAACAGGAGTTTGAGGACGAGGAGCCAGTCCAGGTCTTTGACTATGACTTTGCCGATGAAGCGGAGAGTATTGAGGCGGCGACAGCGAAAGACTCTAATAATGGCTGCTCGGAGAACATAACAGTGCATGTGGAGAAcgagaattttaaatatgaaacgGAAATCATATACAATGAGTCCACCGGCGAGCTACATGCCGAGCCGCTTGAGCAGGCGGAGCAGTTGGCCAAACAGAAGGAATATGAGTTTACTATACGAAATACTGCCAATGGCGTAACGGAGATTAGCCCAGCTGCCATTCCCACCACACAGATGACAACTCGCAAGAGTGCGGCCAAGttgcagcgacagcagcaaacAGACGAGCAACATGAGGCGGAGGAGGATCAGGAGTCACCAGCTAAGCGTATCTCGCGCCGGCGTAGGGCAGCCCAACTGAATGTGAATGAGCAGCAGATCGCAGCTGAAGGCGGCACAAGCCATTTCTCAAAGCAGCCCAAACTCCAGACCATCACTCGTAGAACCCTTAATGGAGTTGCAGCCCCAAGTGTCAGCGGTGTAAATGTGACCCTCAAGTATCACTGTGAACGCTGCAATGCGGGGTTTGCGCTAGAAAAGTCCCTCATCATACATCGCCGTCAGAAGAGCTGCACGAATCGCAACTTCAAGTGCAACGAATGCGATCGTGTTTTTGTCTCGCCAGATCATCTGGCCGAGCATCGGGCCACAGTGGCTCATGGTGCCCACAGCTGCCCGGAGTGTAGCCTGCTGTGCGAATCCAAAGAAGAATTGTCCATGCACATGGTCCAGGGCCACAAGCGTAGTCTGCGGCATCAGTGCAACATTTGCAAGAAGGTGTTCACCATGCTGTCAACGCTGCGGGATCACATGCGCATCCATACCGGCGAGAAGCCATTTGTGTGCAATATCTGCGGCAAGAGTTTCACACAGAACGCCAATCTCCGCCAGCATCAGCTGCGCCATTCCGACATCAAACGCTTCAAATGCGAATTGTGCGCCCACAAGTTTGTCACCAAGGCGGAGCTGACGTCACATGCCCGCACCCACACCGGCGACAAGCCATTCGTCTGCGAGGTGTGCCCGGCCAAGTTCTCCACCAGATGCTCGCTGGCCAAGCACAAGCGCAAGCATACGGGCGAACGGCCCTATGCCTGCGATCTGTGTCCCATGCGATTCACGGCCTTGAATGTGCTGAAGAATCATCGCAGGACCCACACCGGCGAGCGTCCATTTGTGTGTCCGTTCTGCTCGAAGAGCTTCACGCAGCGCGGCGATTGCCAGATGCATCAGAGAACACATCAGGGCGACAAGATCTACATATGTCCAGTGTGTGCCCAGGAGTTTGAGAGTATGCCGGATATGCGACAGCATTTGTCTGAACATCAGCAGGAGGACAAGCGACTGGTGCACTTTACATTGATTAGCAACAAGGAGAATGACCATGGTGCGGTGaccgaggaggaggaggaggaagaagaGGACAATCccacgacgacgacaacaacggATGCAAATGCATCGCTGCTTCTCTAA
Protein Sequence: MDVSKVCRTCLNVTGPFMTIWGAGSCVADMLRGFTKTNPRPGDNLPQNVCIPCISEISRCHEFKSKIESTCRTLHQLLSLPEELLDDVAVPIKPEVVTADIAVQTCAAGAATTATVEVQTDVYTNNAARDEQEFEDEEPVQVFDYDFADEAESIEAATAKDSNNGCSENITVHVENENFKYETEIIYNESTGELHAEPLEQAEQLAKQKEYEFTIRNTANGVTEISPAAIPTTQMTTRKSAAKLQRQQQTDEQHEAEEDQESPAKRISRRRRAAQLNVNEQQIAAEGGTSHFSKQPKLQTITRRTLNGVAAPSVSGVNVTLKYHCERCNAGFALEKSLIIHRRQKSCTNRNFKCNECDRVFVSPDHLAEHRATVAHGAHSCPECSLLCESKEELSMHMVQGHKRSLRHQCNICKKVFTMLSTLRDHMRIHTGEKPFVCNICGKSFTQNANLRQHQLRHSDIKRFKCELCAHKFVTKAELTSHARTHTGDKPFVCEVCPAKFSTRCSLAKHKRKHTGERPYACDLCPMRFTALNVLKNHRRTHTGERPFVCPFCSKSFTQRGDCQMHQRTHQGDKIYICPVCAQEFESMPDMRQHLSEHQQEDKRLVHFTLISNKENDHGAVTEEEEEEEEDNPTTTTTTDANASLLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -