Hdun010168.1
Basic Information
- Insect
- Hirtodrosophila duncani
- Gene Symbol
- hang
- Assembly
- GCA_037043425.1
- Location
- JBAMBM010000704.1:5928505-5943659[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 0.41 26 5.7 1.0 3 23 554 575 553 575 0.93 2 19 0.3 19 6.1 3.5 3 22 681 700 679 700 0.89 3 19 0.00089 0.056 14.1 3.3 1 22 788 809 788 811 0.90 4 19 0.1 6.4 7.6 0.1 2 21 823 842 822 843 0.93 5 19 0.0044 0.28 11.9 0.1 2 23 997 1019 996 1019 0.93 6 19 0.0018 0.11 13.1 0.1 1 23 1027 1050 1027 1050 0.97 7 19 5.3e-05 0.0033 17.9 0.1 2 23 1145 1166 1144 1166 0.97 8 19 0.00042 0.027 15.1 2.9 2 23 1259 1281 1258 1281 0.97 9 19 0.089 5.6 7.8 0.2 2 23 1290 1312 1289 1312 0.95 10 19 0.0048 0.3 11.8 0.9 1 23 1325 1348 1325 1348 0.97 11 19 0.00019 0.012 16.2 1.1 1 23 1390 1412 1390 1412 0.99 12 19 0.0029 0.18 12.5 0.9 1 23 1420 1443 1420 1443 0.96 13 19 0.077 4.8 8.0 0.8 2 19 1451 1468 1451 1469 0.95 14 19 0.00011 0.0067 17.0 0.4 3 23 1532 1552 1531 1552 0.98 15 19 0.0075 0.47 11.2 0.1 1 23 1587 1609 1587 1609 0.97 16 19 0.0009 0.056 14.1 0.7 2 23 1692 1714 1691 1714 0.93 17 19 3.7 2.3e+02 2.7 0.2 2 20 1734 1752 1733 1754 0.91 18 19 0.0098 0.61 10.8 0.4 3 23 1769 1789 1769 1789 0.98 19 19 0.0001 0.0063 17.1 2.1 1 23 2119 2141 2119 2141 0.99
Sequence Information
- Coding Sequence
- atgtGCGACACTGCCGCAATAACTACAGTGGCAGCAGGCGCAACGACGGCGCCAGTAGCCGCCGTCACCACGAATACATCATCAGCCACGGCGGAGCCGCCACAGAcggtgcagcagcaacaatggaCGCGACAAAATTGTTGTCGCCTCTGCCTTGCTCCATCCAGCGAATGTATATCGATCATCAATAGTTATGCAGCCGATAAGGAGCCGCTGTCCACCAAAATCCACAACTGCGTAAATATCAAGATCACTTCAAAGGATCGCCTCTCGCTGCAGATATGCCATGCCTGCATTAGCTATTTGAACTCGTGGCAAAGTTTCAGGAATCGCTGCTTTAGCTCACAgaccaaacagcaacaatggctggcggacaacaaaagcaaatggtTGGGCTACCTGAAGTTGAACAGCAGTTCTGCAGCCGATGCCGCCGAGAatggaggagcaggagcagccttTGACcatcagaagcagcagcagcagcagaagttacaaaatgaaactgatgcagcagctgctgccactgccgcagCGGAAAAGGCATCCTCATCGGCCGCTAACATATTGGATGGCATACCATCGCTGAAGAAACGCAAATCCTTAACAGTCTATGTGAgtccaaaacaacaaatcgtacaacaacaacaacagctacagcagcaacaacaacagcaacagcagcaacaatttgctGCAAGATTGACGAGCGCCACGGCGGCGGCAGCCACACAGCAGCAAACATTGCAAACCCTATTGTTACACGTGCCGGCGGCGACAGCCAGCACATCATTAACCTTTACCCATAGTCCtgtccagcagcaacagcagcggcatccacagtaccagcagcagcatcaacaataTCATCGTCGACATTATCAAACACAGCGCGGCAAACATCACCATCAGCGTCagccacatcatcatcatcatcagccacAACGACGACCACGTCAACCACGTcgccaacagcagccacagcagcagcatgttgTTGGCCATCCATCTGCTCCTGCAGCAGGTCAACGAAGTTTGACGAAATTAAAGTCcaaattgtatttgccatTGGACATCTCagtgccgccgctgccgcctgCCCCCGCGTCATTGATGACAAGttgtgctgctggtggtgctgctgctgtcactGCTGCTGTTACGGCTACGGCTACTACTGTGTCCGCTCCAATACCGCAACCACAGACTTCTGTTCCCCCTCCCTCTTCCCTTACTATGCCGTTGTCGCTGCCCCTTGATTTCAGCCAGAATCCAAATATCTCAACATTGCCGCCGCCGGCGCCGTCAATTAACAACAGctgcagtagcagcagcagcaacgttCGTGTCGTCGCCGCCTCCACAGCTGCCGCCTCAACGCCACTGCTTATGCCGCCACTGCCTGCCATTCCCATCAAGGATGAGCCCATGGACGATACGGATGatgattttcaaatgaaatccaTTGACGAGTCGGATGATATGGTAGATCCAACTATGTTCCTAGAGCGCTCCGAGCATGAGGGCGATGTACCATTAATGaCCTCCGACTATGATTATACGGCTCAGCATGGCGTCAATGCTGCCGTGGCGGCTGCCTCGCTGCCCCCCAATGCTGTGGCCAATGTGGCAGCTGCCGGGGATTCAAAGGTAGCCAGTTGCCGCGCCTGCAGCCTGCAGTTCTCCACACGCGCCAATGCCCGCCGCCATGAGCGCAATCTGCATCCGAATCTGTTCCAGCTGTCCACGGACTCGCCCAACAACACACCCATAACCAAGCCTACACCGGCTCTGGCCGCCGCATTGGAGATTCAGCGCGCcgccgctgcagccgccaGCGAGGAGGCGTCGCGGGCCGCTGCTGATGGTAACATCTCAACCCAAAAGTACAGGCAGGTGGTGATGAATGCCTTCATCAAGTGCGAGGGCGGCGGCTATGACTATGATAATCCGGAGCAGTACCAGTCGCTGCTTAGCCGAGACAAGGTCGAGTTCCTGCAGCAGAACAGCGAGTTCCTCGAGCAGTATCAGACAATGACGTGCCGCTGCTGCAACAAATTCTTCTCCACGTACAAGAACTTCATGGCGCATGTGCGCAAGAAGTATTCACAGCTGCCGCGCAATCTGTGCTTCAATTGCCTCAAGATGAACGACTCCAAGGCGCTGTTCATCTCTCATTTGAAGAAGCGGAACTGCATCAATCTCTATCGCGTGCTCAATGCGCTAAATGCCAAGCAGCCCAACTTTGGCGGCGGCAGCGACAATTTGGAGCAGCCGGTAACAGCGGCAGTGGaaccacaacagcagctgcaggagcGTCCCGAGAAACTGCGCGCCAAGGAGCTGCTGGTGAATAAGCTGTACGAGTGCAAGCTATGTCCCAAGGGTTTCCGCACGAAGCACGAGTTCCGCACCCATGTCTATGACAAGCACGCTGATGTCCAGCGCAAGGATAACAACTCGATCCAATGCAGCTTCTGCGGTTTGGACTTTGCCGATCCGGTGGACAGGCGGCGGCATTACAACAACATGGACTGCATTGTCCGACTGCGCTGCATGACCTGCGATGCCAAACTGGAGACGCATCAGCGCTTCTTGGACCACGTATATCAGGATCATTTGGGGGGGATTAGCAGCGACAATGCCTCCTCACAAGGGGGGACACCGCGCGGTAGCAGTATGGATCATTCGCCGGGCAAGCGTAGCCTGCTGGGCGCCCTCGGCATTGTTGCCAGCTCCTCCAATTCCAATGATGAGtcacgcagcagcagcgtccCGCTGCCTCCGCTAACATCCACGCCCAAGCCGATCGGCGgatcagcatcaccagcagccAAAGGAGCAGCGGCTGCAGCCGGCGGCGGAGGCAGCCTTAGCAAATCTGGCAAAGCTGCGTCAACATCTGCAGGCCATCGTGACACATCGTCGTCCGGCGCCGCCACCGCCCCCGCTGCACCCAAATCCCAGTACTTTTCGCGCATGCCGCAGGTCTGTCCTGTTTGCGGGCAGCAGTACAACAATTATAACAATGTGCTGCGCCACATGGAGGCGCGCCATCCCAACAAACTGCCGGAGACGTACAAGTGTGTGCGGTGCGGACTTGGATATCCGCGCATCTCCTACCTGCGGGAGCACATGATCGTTGCGCATGGTCTGGACAAGAATCGGCACTCGGGCGGCTTTGAGTACATTGTGAATGCGGATGCAGTCAAGCTGGCCGATGGGAGCACCCCAAATGTATACACCGGCCGCTATGACTATGTGATGAAGGATCTGATGTCCATAACAAATGGTGGGACCCTCGATgacgaagatgatgatgaggatgagtcAGCCGGTGGCAGCGCCCCCAAGAAGATGCGCCTCGACgatagcagcaacagcagtgtCGTGGGCGTGGCCGTGTCCTCTTCAAGTGCCAACCAGCAGAAGGAGTGCCCCATCTGCAATGCGgtgttcaacaacaacattggcCTATCCAATCATATGCGCTCCCATTACACCGCCTCCAGTGCCACAAATGCAGCGCTCGCGGCGGCCAATCGCATGACGCCTAAATCCCTGACAATAACAGCCGCGCCAGCAGCTGCCGCGGGATCAGAAACTGCAACAACGACAAGCACGCCAGCGGCGGTTTCAATAGCGGCAGCTAACACCACAACGACGGCAATGGCATCTGGAGATGGCGCGGTCAAACAGCCATCGGCGGTGCACGAGCACGCCGTATTCCGTCGCAGCTTGGATCAGGCAGCCGATCGGCGTTTCCGACGCATGCGCTGTCGCATCTGCCAGCGGCGCTTCAGCTCGAAGAAGTCGTATCGCTACCACATGCTCACCGACCACCAAGTGCAGAATGTCCAGTTCATCAAGTGCAAACTGTGCAGCGCCGAGTTTGCCTACGAGAAGGGCCTGAAGGTGCATCTGTTCAAGGTGCACGGGCGCGCCATCAAGGATGAGATGATTGTCAAGCAATTTGAGTGCGATATATGCTCCACTGTGTATAGCtccgagctggagctgcatCAGCACAAGCGCAGTGTGCACAAGTTGAGcgcaggaacagcaacaattaCATCATCCGACGAGACACTTAAGTCGGCGGCCGGCGGTGGCGGTGATCTCGGTGAGACGTCGACAGTTGCGCCCGCAGCGGCGCCACTGTATTGGTACCAGTGTAAATATTGTCCATCCAACTTCAACACTAACAAGAAGCTGGCCATCCACATCAACTCGCACGATGAGTTCGATTCGAATGATTACTCCTGCAAGGATTGCGGCAATGTCTACAGCGGACGCAAGAGTCTATGGGTGCATCGCTATAAGAAACATCCTCAGGTGCCCGATCCGGCCGAGTGCACGCTGTGCCGCAAGATGTTCTTCAATCGCCAGATGCTGAACAATCATACGCCCACCTGCAATCGTAAACCGATCACGGCCACCGGCgcccatcagcagcaacagcatgaTCAACAGCAGTCACGCAGCGTTTTCAAGCACAAGACTGGCGAcgacgatgaggatgatgaggaACAGCAGCTGGATGATAGCATTGCGGCGGCGGCGAACATAAAAATTCGCATTCCGGAAGTGGCGTGCACCATTTGCGGGGCCCGCTTCACTGACCAGGAGATGTTCAGCAAGCACATCCAGAAGCACGAACAGGAGCTGTATGTGGACAATCCGCTGGCGGCCATGTTCGACGATGGGCCGGCCGATCCCGGCCAGTTTGAGGTGGAGCGCCAGAACGAGAACGGTGAATACGCGTGCGATCTATGCGCCAAGACGTTCCCCCAGGTGATTGCGTTGAAGGTTCACCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGaatccCATCATCGACGGCGAAGCGACAACCACCttgaacaacagcaacaacatcaacaacaacaacaactcgacacTGCATCTGCGAGAACTGCATGCGGTGGGATTGACGCCCAaccagcagcagaaacagaagcatCTGCCctccagccagcagcagcatctggtgggcagcagcagctcctccaCATCGAGGAGCAAATCGCAAAAACGGAAACGTGAATTGAAGTGCGATTATTGCGCCTCCACcttcatcagcaacaacaacctgCGTCGCCACATGTACGAGCTGCATAAGCATGAGGTTAGCAATCTGCCGGAGCCACCGGTCATTGAGGTGGACAAACCGTTGTCGTGCCGGCGCTGTCAGCTCAAGTTTGAGACGAAGGAGCTGTGGATCGAGCACAAGCTGCAGGATGCCAAGGTGGTGCGTCCATTCTGTCCATTCCAATGGGGCTGCGATCTGTGCGGCGAGTATCTGTCGCGCAAGGAGAAGCTCATGAATCACATTAACAATCATCTCAAAGAGGAGGTGATTGTTCCAGTGGCGGCAAAGGCAGAGGCGGCGGCGAAGACGACCATCCAGCAGCAGGCGGAGCAGAATCCACATGACTCAGAtgaacaggagcagcaggctAAGGCTGATGTTGTTACTCTtgcagagcaacagcaggaggaacagcaggaggaggaggacgagCAGGATAATGTGGACACTGAtctagatgatgatgaagacgaTAGTTCTGACGATGAAGATAGCTCTGGCACaggcgatgacgatgatgatgacgatgaagaagaagaagacgacgAAGACGATGCTGACGATGAAGGGGCGGAACAGAGCGGTGCCGAAGTGCCGCAGATTAATAATGCCAATCACAATCATAATAcggctgctgatgatgatgatgatgatgatgatgacgatctGGTCGAGTTGGTtgaagaagaggaggaggaggaggaggacgaggacgaggatgTGACAGCAGCGGCTGCAGTGAACGAAGTTGAAGCCGAAGCCATCAGTTCCGATGCCGATGGTATCGATgaagatgataatgatgatataacagatgatgataatgatgatgatataacGGATGAAGATGTCGATTCTGCTGCCAAATCAGGCAAATATGTCAATGGCAAACCCTCATCTTCATCGGTGACGTCTTCAGTGGCACAGCCGGTACAGCCACTAATCGTGCACAGTTCCGAGGATGACGACGAGGAGGAATGTGATGGCATAATGGCCATTGATGATATTATTGAAGAagttgttgatgatgaaatGGTGGTTGCCGATGCAGAGAATGGCTGTATTGTTGAAGAACAAGAAGtagaagatgatgatgaagatgatgatgagggcGGCGGCAGGCATTCCTCCACAACATCGTCATCCGAGAGCGATTCGACAACCACCAGCTCCTCGCAGTCGTGTTCAACGGGTGAGCGGCGTaaaaacgcagcagcagctgtgggGTCTAAACCCAGCTATACGTGTGATCTATGTCAACTTTGTTTCGATTCCCAGGAGCTACTACAGACCCACATCAAAAGCCATTTCCTCAATGGGCCGCAGGCACCAGtggtgacaacaacaacaacaacggcagtAGCAGCGGCCACAAAGACGACGACGGGCGGCGGCGTTgctagaagcagcagcagcagctctagcaacaacaacaataaaaccaaaacaacagaAGTGATGACGAAGACAACgacaactgcagctgcagctggcggCAATTGA
- Protein Sequence
- MCDTAAITTVAAGATTAPVAAVTTNTSSATAEPPQTVQQQQWTRQNCCRLCLAPSSECISIINSYAADKEPLSTKIHNCVNIKITSKDRLSLQICHACISYLNSWQSFRNRCFSSQTKQQQWLADNKSKWLGYLKLNSSSAADAAENGGAGAAFDHQKQQQQQKLQNETDAAAAATAAAEKASSSAANILDGIPSLKKRKSLTVYVSPKQQIVQQQQQLQQQQQQQQQQQFAARLTSATAAAATQQQTLQTLLLHVPAATASTSLTFTHSPVQQQQQRHPQYQQQHQQYHRRHYQTQRGKHHHQRQPHHHHHQPQRRPRQPRRQQQPQQQHVVGHPSAPAAGQRSLTKLKSKLYLPLDISVPPLPPAPASLMTSCAAGGAAAVTAAVTATATTVSAPIPQPQTSVPPPSSLTMPLSLPLDFSQNPNISTLPPPAPSINNSCSSSSSNVRVVAASTAAASTPLLMPPLPAIPIKDEPMDDTDDDFQMKSIDESDDMVDPTMFLERSEHEGDVPLMTSDYDYTAQHGVNAAVAAASLPPNAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAASEEASRAAADGNISTQKYRQVVMNAFIKCEGGGYDYDNPEQYQSLLSRDKVEFLQQNSEFLEQYQTMTCRCCNKFFSTYKNFMAHVRKKYSQLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALNAKQPNFGGGSDNLEQPVTAAVEPQQQLQERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGISSDNASSQGGTPRGSSMDHSPGKRSLLGALGIVASSSNSNDESRSSSVPLPPLTSTPKPIGGSASPAAKGAAAAAGGGGSLSKSGKAASTSAGHRDTSSSGAATAPAAPKSQYFSRMPQVCPVCGQQYNNYNNVLRHMEARHPNKLPETYKCVRCGLGYPRISYLREHMIVAHGLDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDEDDDEDESAGGSAPKKMRLDDSSNSSVVGVAVSSSSANQQKECPICNAVFNNNIGLSNHMRSHYTASSATNAALAAANRMTPKSLTITAAPAAAAGSETATTTSTPAAVSIAAANTTTTAMASGDGAVKQPSAVHEHAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCSAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECDICSTVYSSELELHQHKRSVHKLSAGTATITSSDETLKSAAGGGGDLGETSTVAPAAAPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFNRQMLNNHTPTCNRKPITATGAHQQQQHDQQQSRSVFKHKTGDDDEDDEEQQLDDSIAAAANIKIRIPEVACTICGARFTDQEMFSKHIQKHEQELYVDNPLAAMFDDGPADPGQFEVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIIDGEATTTLNNSNNINNNNNSTLHLRELHAVGLTPNQQQKQKHLPSSQQQHLVGSSSSSTSRSKSQKRKRELKCDYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDKPLSCRRCQLKFETKELWIEHKLQDAKVVRPFCPFQWGCDLCGEYLSRKEKLMNHINNHLKEEVIVPVAAKAEAAAKTTIQQQAEQNPHDSDEQEQQAKADVVTLAEQQQEEQQEEEDEQDNVDTDLDDDEDDSSDDEDSSGTGDDDDDDDEEEEDDEDDADDEGAEQSGAEVPQINNANHNHNTAADDDDDDDDDDLVELVEEEEEEEEDEDEDVTAAAAVNEVEAEAISSDADGIDEDDNDDITDDDNDDDITDEDVDSAAKSGKYVNGKPSSSSVTSSVAQPVQPLIVHSSEDDDEEECDGIMAIDDIIEEVVDDEMVVADAENGCIVEEQEVEDDDEDDDEGGGRHSSTTSSSESDSTTTSSSQSCSTGERRKNAAAAVGSKPSYTCDLCQLCFDSQELLQTHIKSHFLNGPQAPVVTTTTTTAVAAATKTTTGGGVARSSSSSSSNNNNKTKTTEVMTKTTTTAAAAGGN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -