Hdun003458.1
Basic Information
- Insect
- Hirtodrosophila duncani
- Gene Symbol
- kipf_1
- Assembly
- GCA_037043425.1
- Location
- JBAMBM010000098.1:1572307-1575530[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.013 0.82 10.4 1.2 3 23 192 212 190 212 0.92 2 14 0.032 2 9.2 4.2 2 23 219 240 218 240 0.95 3 14 0.0036 0.22 12.2 1.9 1 23 246 268 246 268 0.96 4 14 7.1e-05 0.0044 17.5 3.2 1 23 274 296 274 296 0.98 5 14 2.8e-06 0.00018 21.9 2.1 1 23 304 326 304 326 0.99 6 14 0.0012 0.077 13.6 0.2 1 23 330 352 330 352 0.98 7 14 0.0016 0.1 13.3 2.3 2 23 492 513 491 513 0.97 8 14 3.2e-05 0.002 18.6 4.5 1 23 519 541 519 541 0.97 9 14 0.00039 0.024 15.2 0.1 1 23 547 569 547 569 0.97 10 14 2.5e-05 0.0015 19.0 1.2 1 23 577 599 577 599 0.98 11 14 0.00016 0.0098 16.5 1.1 1 23 603 625 603 625 0.99 12 14 5.6e-08 3.5e-06 27.3 1.7 2 23 740 761 739 761 0.97 13 14 0.0012 0.074 13.7 5.9 1 23 767 789 767 789 0.98 14 14 0.00057 0.035 14.7 1.3 1 23 794 817 794 817 0.97
Sequence Information
- Coding Sequence
- ATGGAGAACTACTGCCGGGTTTGTATGGACAGCACAGTTACGCTTGTGGACATATTTTCCAATGACTCCTCCGAACCGGAGAGTGAAGACAGTGTGGCTTTCATGCTAAATGAATGTGCCGACTGTGTAGTGAAGCGCGACGATTCTCTGCCACAACACATTTGCCTATCCTGCGTCTTGGCCACACAAAATGCATTCAGATTCAAGAGGAAGTGTGAGGAGAGCTACCGGCGATTCTGCCACCTGCTGCAGATAAGCCGGGAGCAAGACCGAGAGCTCAGCAGTCAACAAgatcagcaaaagcaaaaagtgaTAGAGAAACCTGTGCAACTTCCTGCACAGATAGCTGCCACCAAGGTGGACCAGCCTTCTTTAACGATAGACATAGACGTAAGCTGCGTCAAAATAGAGCCAGGCTTAAGTACACCGGCAATTGACAGCGTAGACGGCCAGTCGGAAGAGCTTTCTGTATTACAGGAGACGCTGCAGCCGCAGGCCACAACGTTGACCAATAGTTCTGCTCCGGTGACGGCAAACACGCAGCAGCAAGGCTACAAAGATAAATCCATAACCTGCATTGAGTGCGGCATGTTGTGCTCAACGAGAAAACTGCTGCAAATCCATATGCGTCAGCACACTGGGCTAATGCCCTGCAAGTGTAGGTACTGCGGCAAGGGATTCATGAGAAAGAATATTTTGAGACTGCACGAGAAACGCCATACTGGTGAGAAGAACCACTTCTGCGATGTATGCGGTAAGGGTTTCCTACGCAAGTATGATATGACCCTACACGCTCGACGGCACACTGGAGAACGGCCATACAAGTGCTCCCACTGTCCACAAACTTATAAAGATCTTCAAACGCTCAAACTGCACATGGACAGGCATGTCTCCCAGAAGGAATACACATTCAGGTGCAGCCAATGCCCAAAGGGATTCAACCACAACGATGAATATATGAGGCACATTCGTGTGCACATGAAGCCCTTCAAGTGTCCGCATTGCCCATCGGCCTTTTCATTGGCCCGTGTTCTCAATGCTCATGTGCGCGGACACACCAGGGTGAGGATCGCCGCCACTGAAAGGCAGTCTCTCAGGAAACAGCCAACTGACCCCGCTCGTAAGCTGAGCGCAAATGTTGAAGCTAATCATCAAGCATCCAAGGAGTCGGCACCAGCACAAAGATTACGCAACAGACCAACAGTTGGCAGCTATGAGGAGCTGAGCACAAATGCTTATGTTGAAGCTAATCATCAAGCATCCGCATCCGAGAAGTCGGCACCGTCACAAAGATCACCACGCAGTAGACCAGCAGTGGGCAGCTATGAGGAGCTAGATTCAGAAGACAGCGAGAAGAGACGTGTTCGCGCGAAGCCAAAGTCACGGCCGGAATTGGCAAATAATCTAGAAGCCATTCCGGAGACAGACATCAAACCACAGATACTTCAAGGTGCTCTCAATGACAAGCCGCTGAAATGCAAATTCTGCGGAAAGGGATTCGAGCATGCCCGTTCTGTACGCGAGCACGAAAAGCGCCATACTGACAAGAAGAAACACGTCTGCAATATGTGTGGTAAGGGCTTCTTCCGCAATTGCGAATTGATACGACACCAACGCCAACATACTGGTGAACGACCTTACAAGTGTCCCTACTGCCCGAGTGCCTATACCGGTCTCAACAGTCTGAAGAAACACATTGGCATCCATGCCAGACAGCGGGCCTACAAGTTTAAGTGCACCAATTGTCCCAAGGGTTTCAATAGGCACGCTGACCTGGTGAGCCACGTTCAAATGCACGCAAAGCCCTACAGGTGTACGCAATGCCCGGCAATGTATACCCAggtatataaattgaatatgcACATGCGGCAACACATTCCAGTGGTGGATACGGTTCCCACAGCTGACAAACAGCCACAgtcgcagccacagcagcaacggGTGATAGGCAAAAATGCTGAAACGTCAATGCAGCCTCAAGAAACGGAACATGGCTTACGGAAGAGACCAGGCGCGGGTACTTACGAGGAGGTTGCTTCAGTGGAAGAAGATATTGATCTGAGCCGTGTCAAGACGGAGATGAATGAGAGTCCTGAAGTACTGAATTACCCAGAAACAAGCAACGAAGTCCAACAGAAGGAGCAGGACAAGACGCCGCCTACCGAAACTACTCTGAAACTGAACTTTGACAACCGCTACTCTGACGACACATCAATTTCCTGCAACTTTTGCGGCAAGAGCTTCACGACCAATTACAAGCTCACGGTGCATATGCGAACGCATACAGGCGAAAAGCCCTACAAGTGTCCCTACTGCGCCTTATGTTTTCGCTCACACTCCCATCTTGGGGTACACAAACGTGGTCACACTGGCGAGCTGTTCCGCTGTGAATTCTGCCCATTGGTTTACCGCGAACGTTTCAAGCTACGTGCCCACATGCAATCCAAGCACAAACATCAAAGCGAAGCATCAACCAGCACCACTGACAAAGTCACCACGAAAAGGTTGGTTGTACGCTTGCCCCGTATTCGATTGCCAAATGTTCAAACAGCGAATGATGAGAAAAACTAG
- Protein Sequence
- MENYCRVCMDSTVTLVDIFSNDSSEPESEDSVAFMLNECADCVVKRDDSLPQHICLSCVLATQNAFRFKRKCEESYRRFCHLLQISREQDRELSSQQDQQKQKVIEKPVQLPAQIAATKVDQPSLTIDIDVSCVKIEPGLSTPAIDSVDGQSEELSVLQETLQPQATTLTNSSAPVTANTQQQGYKDKSITCIECGMLCSTRKLLQIHMRQHTGLMPCKCRYCGKGFMRKNILRLHEKRHTGEKNHFCDVCGKGFLRKYDMTLHARRHTGERPYKCSHCPQTYKDLQTLKLHMDRHVSQKEYTFRCSQCPKGFNHNDEYMRHIRVHMKPFKCPHCPSAFSLARVLNAHVRGHTRVRIAATERQSLRKQPTDPARKLSANVEANHQASKESAPAQRLRNRPTVGSYEELSTNAYVEANHQASASEKSAPSQRSPRSRPAVGSYEELDSEDSEKRRVRAKPKSRPELANNLEAIPETDIKPQILQGALNDKPLKCKFCGKGFEHARSVREHEKRHTDKKKHVCNMCGKGFFRNCELIRHQRQHTGERPYKCPYCPSAYTGLNSLKKHIGIHARQRAYKFKCTNCPKGFNRHADLVSHVQMHAKPYRCTQCPAMYTQVYKLNMHMRQHIPVVDTVPTADKQPQSQPQQQRVIGKNAETSMQPQETEHGLRKRPGAGTYEEVASVEEDIDLSRVKTEMNESPEVLNYPETSNEVQQKEQDKTPPTETTLKLNFDNRYSDDTSISCNFCGKSFTTNYKLTVHMRTHTGEKPYKCPYCALCFRSHSHLGVHKRGHTGELFRCEFCPLVYRERFKLRAHMQSKHKHQSEASTSTTDKVTTKRLVVRLPRIRLPNVQTANDEKN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -