Basic Information

Insect: Hirtodrosophila duncani
Gene Symbol: ZNF296
Assembly: GCA_037043425.1
Location: JBAMBM010000717.1:697291-701976[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.0049 0.31 11.7 1.5 3 23 219 239 217 239 0.95

2 25 0.002 0.13 13.0 1.0 1 23 245 267 245 267 0.98

3 25 0.046 2.9 8.7 0.9 2 23 300 322 299 322 0.94

4 25 0.027 1.7 9.4 3.5 1 23 395 418 395 418 0.94

5 25 2.4 1.5e+02 3.3 1.0 1 20 455 474 455 475 0.94

6 25 1.7 1e+02 3.8 0.5 2 20 499 517 498 520 0.92

7 25 0.0014 0.085 13.5 4.3 1 23 598 620 598 621 0.95

8 25 0.0048 0.3 11.8 0.4 1 22 629 650 629 650 0.95

9 25 0.12 7.3 7.4 7.1 1 23 659 681 659 682 0.96

10 25 0.0015 0.096 13.3 1.3 2 23 712 733 711 733 0.97

11 25 2.3e-05 0.0015 19.1 5.4 1 23 741 763 741 763 0.99

12 25 0.011 0.69 10.6 1.8 1 23 907 930 907 930 0.95

13 25 0.0056 0.35 11.6 0.8 2 22 938 958 937 958 0.96

14 25 0.23 14 6.5 2.5 1 23 967 990 967 990 0.91

15 25 3.1e-05 0.002 18.7 3.0 1 23 1007 1029 1007 1029 0.98

16 25 0.00039 0.024 15.2 0.9 1 23 1036 1058 1036 1058 0.98

17 25 0.00092 0.058 14.0 0.1 2 22 1085 1105 1084 1105 0.95

18 25 0.11 6.9 7.5 4.3 1 23 1151 1174 1151 1174 0.95

19 25 0.2 13 6.7 2.6 1 23 1212 1235 1212 1235 0.95

20 25 8.8e-05 0.0055 17.2 1.8 1 23 1258 1281 1258 1281 0.98

21 25 3.1e-06 0.0002 21.8 0.4 2 23 1308 1329 1307 1329 0.95

22 25 0.00014 0.0089 16.6 3.3 1 23 1335 1357 1335 1357 0.99

23 25 1.8e-06 0.00011 22.6 2.7 1 23 1363 1385 1363 1385 0.98

24 25 1.2e-06 7.4e-05 23.1 1.5 1 23 1391 1413 1391 1413 0.99

25 25 0.0012 0.075 13.7 0.5 1 22 1419 1440 1419 1443 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.0049	0.31	11.7	1.5	3	23	219	239	217	239	0.95
2	25	0.002	0.13	13.0	1.0	1	23	245	267	245	267	0.98
3	25	0.046	2.9	8.7	0.9	2	23	300	322	299	322	0.94
4	25	0.027	1.7	9.4	3.5	1	23	395	418	395	418	0.94
5	25	2.4	1.5e+02	3.3	1.0	1	20	455	474	455	475	0.94
6	25	1.7	1e+02	3.8	0.5	2	20	499	517	498	520	0.92
7	25	0.0014	0.085	13.5	4.3	1	23	598	620	598	621	0.95
8	25	0.0048	0.3	11.8	0.4	1	22	629	650	629	650	0.95
9	25	0.12	7.3	7.4	7.1	1	23	659	681	659	682	0.96
10	25	0.0015	0.096	13.3	1.3	2	23	712	733	711	733	0.97
11	25	2.3e-05	0.0015	19.1	5.4	1	23	741	763	741	763	0.99
12	25	0.011	0.69	10.6	1.8	1	23	907	930	907	930	0.95
13	25	0.0056	0.35	11.6	0.8	2	22	938	958	937	958	0.96
14	25	0.23	14	6.5	2.5	1	23	967	990	967	990	0.91
15	25	3.1e-05	0.002	18.7	3.0	1	23	1007	1029	1007	1029	0.98
16	25	0.00039	0.024	15.2	0.9	1	23	1036	1058	1036	1058	0.98
17	25	0.00092	0.058	14.0	0.1	2	22	1085	1105	1084	1105	0.95
18	25	0.11	6.9	7.5	4.3	1	23	1151	1174	1151	1174	0.95
19	25	0.2	13	6.7	2.6	1	23	1212	1235	1212	1235	0.95
20	25	8.8e-05	0.0055	17.2	1.8	1	23	1258	1281	1258	1281	0.98
21	25	3.1e-06	0.0002	21.8	0.4	2	23	1308	1329	1307	1329	0.95
22	25	0.00014	0.0089	16.6	3.3	1	23	1335	1357	1335	1357	0.99
23	25	1.8e-06	0.00011	22.6	2.7	1	23	1363	1385	1363	1385	0.98
24	25	1.2e-06	7.4e-05	23.1	1.5	1	23	1391	1413	1391	1413	0.99
25	25	0.0012	0.075	13.7	0.5	1	22	1419	1440	1419	1443	0.91

Sequence Information

Coding Sequence: ATGTCAACGTCGGTTATATGCCGCACCTGTGCGCTGCACAAGGGCCATATGCTGCCCCTCTCAACCTGCGCTGAGAAGCATGCGaataaaactttaaatgaaatacttCGTGATCTCACCCAAATTGAGGAGCAGCCCCATTCCGATGAAAATTTACCTCAACACTTATGTGGCGACTGTCATACCAGGCTGGAAGACGCTTTCGCTTTTGTCGTCCAAGCCAGATTAGTAAACGAGCAGCTGTTGTTTCGGCTTAGGGACGGCCTGGACGAGACACCCATAGAAATTCCCACACAGCAGATAAAAACGGAGGTCGATCTGGATGACGAGCGCTGCTCCAATAGTCACAAACTCAATGCGGAGGATATGGCTACATATGTTGTGCCCACGCTCAAGTGGCAGGCGGAGACCGATGACGACGATGTAGGCGAGACAACTGCCGGCGAAGCAGATAACGATGATCTGGACTACAAGCCCGTGCAGCTGCGGCGTAGCTCCCGTAAGACCAAACCGCAAACGGAGGACAGTGAAGATGAAGCCTCTGCTGGCAACTTGGAGCCGGAATTGGAAACTGCAGCCCCTCTTAAACGCCGACGTGGACGCCCACCACGTCTGCCACGGGCGCAAGCTGTCAACAAGGATGGCCGCCATTTGTGCGATGTTTGCGGCAAAAGCTTCTCGTGGTTTCGGGACATGCAACGCCATGCCCGCATGCACTTTGAAGACGCCTCCTACATATGCGACAGCTGCGGCAAGGGCTTTCTGCGCAAGGATAAGTACATGTCCCACCTACGCTCCCACGAGCGGCGCGAGGCCAAATCACAGGGTATCCTCCAACTCAGTCCCGAATGGCGCTTCGCCGAGCGCCTATACAGCTTTGGCCGGTTGAAGCGTCTGGAGTGTAAGCTCTGCGGATTGAAATGCCAGCGGTTGCAGGAGTTGCGCCTCCATCTGGCATCTGAACATGCCAGCATTGAAACGCTTTCGAATCTCGCGGCCAACCATGATGTGGTCAAGGAGCACTTCCCTCTGGAAATGGACTTGGATCAGGTGAAGCAGCAGGTGTGTCAAGACATAAGCGAGGGGCTGCTGGAAAAATACTGCACGGTGGTGAATGCCCATGGCTACGAGATGTCCCTCAGCGATTCGGATGACGAGCCGGAGCCTACTACTGATCCCATTTATAAATGTGAAGCCTGCCATGTATCCTACACCCGCAAGCATCGCCTTGTGCGACACACACTGGAGGAACACACTGATACAGCCATGCTGCATCGTTGTAATCTCTGCAAGATTGGCTTTGTCTGCCTTAGCTTGATGGAGCAGCATCAGCGCACGCAGTGCCACAGCAAGCTGAAGCGTTATCGCTGCCGCAAGTGTCCTGGAAAGTTCATGTGGCTGGAGAATCTGGAAAGGCATCTCTGCCCGCAACGCAAGGACGAAGATGAAGATAAAGAAGTAAATCAGCTGCAACAGCTGAAGGTCCGCCATATACAATGCTGTCTGTGCGATGCCCAGTTGTCCAGCATGTCGGAGCTACGCTTACATCTGCCCAGCCACCGAGATGGCTCCACTGGCATCATTCCAGAGCAGGCAACAGCCTTCTTCCGCTGCTACTATCCCAATGGCCTAGCCTGTAGTCCCAGTGAGCTGGCAGCCAGGATAGCCGGCGACTATGAGGCCAAGGATTATGGTCGCTACTACAGTGCCTGCACAGACAGTGGCCAGGAACTGGATCTCTATGACTCGGACAGCGaagaggaggagcagcagcaaaatcCCCTTGACTTGCACACCTGCGATGTATGCGGTGAGAGCAGAAGCCGTCTCAAATACCTACTCCAACACCAGAGAAGACATCATTCAATGGAAGAGAGACTAGCTCATTCTTGTGAGGATTGCGGGGCTGGATTCGTGGGCCATGAACTGCTCAAGCAGCATCGCCGCCGAGGATGCGCCAAGCGTCATGCCAAGTTCCAGTGTCAGCGTTGTCATCTTCATTTTGTGTGGAAATCCAACTACGAGCAGCATCTGCGAATCCACCATCAAGACCCCACTGATAATGGAGATGAGGCCATAGATCAGGCCCTGGATAGACTGAGAGCCAAACGGAAGTCCACTGCCGCCAAATTGCAGTGCGATGAGTGTGAAAAGGTTTTCATCTGGCACAAGGACTTGACGCGTCACAAGCGCATTCACCGGCCCCAGGCGTCTGCCCAGTACGAGTGCTCCCATTGTGAGCGCAAGTTCCATCGAAAGGATGGCCTTAAGTCCCATATGCGTGTGCATggcgaacagcagcagcagccagtgGAGACCAGCAGCACATCTGCCTCGATCAGTGGTGATCCTTCTATGGTATTGCAGCTGTCCTGTCGTCCAAATGGCTGCAAGCAGATCCAATGCATGGTTTGCCTTTCCCGCCACTCGAAGATTTCTGATCTTCGCAGTCATCTGCTCAGTCACCAGTTTGCTGTGAACTTGGCGGAGGATCGCGATGTGTCCGCCATCTCAAGCTCTTTGTATCCGGAGCTGCCAACGCAGCTGGACAAGCAGCAGCTAATGGATAGGATTATGGGAGACTTGACTCAAGGCCACGATTTAGAGCGTTTCGTTTCCATTACCAACGAGGCGGGCATCGAGCTTAGCCTGGACAGCAGCGAAACTGACACGGATTCTGAGACGGAGCAGGAAATGGCCCATGGCAAACGGCGTGTGTACACCTGCGATGTGTGTCACCTGGAGCTGCCAAGAAAGCATCAGCTCTATGCCCACCAACTAGAGCAGCATGATGGCCCAGAAGCGGGCAGCGTGTGTGGACACTGCCAGCTGAGATTTGTCAGTGAACGGCTGCTGGAGCACCATCTTCGCACCCAGTGCCGTAATCCCCAGAAGCGCTTCCTGTGCCGCAAATGCCCACTGCGCTTCCGCTGGCGACAGAACCTCAAACACCACACGAGTGTGGCACATCGTGAACAGACACATACAGAGGTGGATGCAGACTGTCCGCCAGTTAGCTTCGAGTGCACGGAGTGCAATCGGAGCTTTAAGATGCAGAAGGACTTTACGCGGCATCGCCTGATGCACGGCAATGAGGGGAGCATATATCGATGTCGTTGGTGCGCCCGTCGCTTCTATCGCCAGCCCAATCTACTCCAGCACATTGAGCGACATGGGATCAGCGCTGGGCAGCTGCCCTATGCGGAGGCCTTGCTGGATGCCAACCGGCATCCCAATGGTCTGAAGTGCATCCAGTGCAAGGTGTGCGATGTGAGCTTTGCTACTATCCATGACCTGCGTGTTCATCTCCAAACCGCAGCGGAGGGCACACATCATAGACTGGACTCCCTGGGCAACTACTCCATTACCAATCAGCATGGCTATGAACTCCACCTGGACGACTCGGAGACTGGCGAGGAGGATTCGAAGTCAGAGGTTACTCCATCGCACTATACGTGCTCCATGTGTCAGTTGCGTTGCGTGCGCAAGTATGAGATGCACCAGCATCAGCTGGCCATGCATCGGCTGGAGAAGATTCCCGATGGTTGCGATCAATGCAAGATCTTCAAGAGCGTCTCCAGCGACCTCATTGTCCATCATAAGCGTGTGCAGTGCGGCAATACGGAGAAGCAGTTCAAATGTTCTAACTGTAGCTATAAATTCATGTGGGAATCCAATCTTTTGCTGCACATGCATCTCCAACATCCTGTCAAGGAGGGCGCGGAGCAGCCAACGCCAGCCACCAGTGCGGTGCAGGCCGAGCCGCAGATTTTCCAATGTGCCTTGTGTCCGCGCAAGTACAATCGCAAGGATCGACTGACGGCTCACATGAAGAAGTTCCATGCGCCTGGGTCAGATGGAGAAGTACCAGCAGCTCCGCCTGTTATCCAGCCGTCGCCGGAGAAGGAACAGAAGCGCTTCCTCTGCGCATTCTGTGGCAAATCGGTCAGCTCCTCCTCCAATCTGATCATCCACATGCGACGGCACACAGGCGAGAAGCCCTTCAAGTGCGATTATTGTGACATGGCCTTTCCGCGCTCCTCGGACCTTCAGTGCCATCGACGCAAGCACACCGGCGAGCGTCCTCATGTCTGCACCGTCTGTCAGAAGGGCTTCGCCCGCTCCTAcaagctgcagcagcacatGCGCACCCACAGCGGCGAGAGACCCTACAAGTGCACCTACTGCGAGAAGAGCTTCGCCCAGTCCAATGATCTGACCCTGCACGTACGCCGGCACACTGGCGAGCGCCCGTATCAATGCGGCGTCTGCGGTGAGCGTTTCATTCAGGGCACAGCCCTGAAGCATCATCGTCAGCAGCAGGCCCATTACGAGGAGGGTACATCGGCGGAGACCAGTTCTACATCTCGACAGCGTCCTGTTCTGGAGCAGTTTGTAGCAGCGCGTTAA
Protein Sequence: MSTSVICRTCALHKGHMLPLSTCAEKHANKTLNEILRDLTQIEEQPHSDENLPQHLCGDCHTRLEDAFAFVVQARLVNEQLLFRLRDGLDETPIEIPTQQIKTEVDLDDERCSNSHKLNAEDMATYVVPTLKWQAETDDDDVGETTAGEADNDDLDYKPVQLRRSSRKTKPQTEDSEDEASAGNLEPELETAAPLKRRRGRPPRLPRAQAVNKDGRHLCDVCGKSFSWFRDMQRHARMHFEDASYICDSCGKGFLRKDKYMSHLRSHERREAKSQGILQLSPEWRFAERLYSFGRLKRLECKLCGLKCQRLQELRLHLASEHASIETLSNLAANHDVVKEHFPLEMDLDQVKQQVCQDISEGLLEKYCTVVNAHGYEMSLSDSDDEPEPTTDPIYKCEACHVSYTRKHRLVRHTLEEHTDTAMLHRCNLCKIGFVCLSLMEQHQRTQCHSKLKRYRCRKCPGKFMWLENLERHLCPQRKDEDEDKEVNQLQQLKVRHIQCCLCDAQLSSMSELRLHLPSHRDGSTGIIPEQATAFFRCYYPNGLACSPSELAARIAGDYEAKDYGRYYSACTDSGQELDLYDSDSEEEEQQQNPLDLHTCDVCGESRSRLKYLLQHQRRHHSMEERLAHSCEDCGAGFVGHELLKQHRRRGCAKRHAKFQCQRCHLHFVWKSNYEQHLRIHHQDPTDNGDEAIDQALDRLRAKRKSTAAKLQCDECEKVFIWHKDLTRHKRIHRPQASAQYECSHCERKFHRKDGLKSHMRVHGEQQQQPVETSSTSASISGDPSMVLQLSCRPNGCKQIQCMVCLSRHSKISDLRSHLLSHQFAVNLAEDRDVSAISSSLYPELPTQLDKQQLMDRIMGDLTQGHDLERFVSITNEAGIELSLDSSETDTDSETEQEMAHGKRRVYTCDVCHLELPRKHQLYAHQLEQHDGPEAGSVCGHCQLRFVSERLLEHHLRTQCRNPQKRFLCRKCPLRFRWRQNLKHHTSVAHREQTHTEVDADCPPVSFECTECNRSFKMQKDFTRHRLMHGNEGSIYRCRWCARRFYRQPNLLQHIERHGISAGQLPYAEALLDANRHPNGLKCIQCKVCDVSFATIHDLRVHLQTAAEGTHHRLDSLGNYSITNQHGYELHLDDSETGEEDSKSEVTPSHYTCSMCQLRCVRKYEMHQHQLAMHRLEKIPDGCDQCKIFKSVSSDLIVHHKRVQCGNTEKQFKCSNCSYKFMWESNLLLHMHLQHPVKEGAEQPTPATSAVQAEPQIFQCALCPRKYNRKDRLTAHMKKFHAPGSDGEVPAAPPVIQPSPEKEQKRFLCAFCGKSVSSSSNLIIHMRRHTGEKPFKCDYCDMAFPRSSDLQCHRRKHTGERPHVCTVCQKGFARSYKLQQHMRTHSGERPYKCTYCEKSFAQSNDLTLHVRRHTGERPYQCGVCGERFIQGTALKHHRQQQAHYEEGTSAETSSTSRQRPVLEQFVAAR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -