Basic Information

Insect: Hirtodrosophila confusa
Gene Symbol: Zbtb41
Assembly: GCA_035043065.1
Location: JAWNNI010000025.1:241261-242940[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 8.6e-05 0.0071 17.2 2.2 1 23 92 114 92 114 0.97

2 11 1.8e-07 1.4e-05 25.7 1.4 1 23 120 143 120 143 0.97

3 11 1.1e-05 0.00094 20.0 0.5 1 23 149 171 149 171 0.97

4 11 6.3e-05 0.0052 17.6 0.4 1 23 177 199 177 200 0.95

5 11 1.8e-06 0.00015 22.5 0.9 1 23 207 229 207 229 0.97

6 11 0.0081 0.66 11.0 1.0 1 23 235 258 235 259 0.95

7 11 0.046 3.7 8.6 0.1 2 23 265 286 264 286 0.96

8 11 2.4e-05 0.002 18.9 2.7 1 23 292 314 292 314 0.98

9 11 2.2e-05 0.0018 19.1 4.7 1 23 320 342 320 342 0.99

10 11 0.0028 0.23 12.5 1.3 1 23 348 373 348 373 0.95

11 11 0.00067 0.055 14.4 0.0 1 20 379 398 379 400 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	8.6e-05	0.0071	17.2	2.2	1	23	92	114	92	114	0.97
2	11	1.8e-07	1.4e-05	25.7	1.4	1	23	120	143	120	143	0.97
3	11	1.1e-05	0.00094	20.0	0.5	1	23	149	171	149	171	0.97
4	11	6.3e-05	0.0052	17.6	0.4	1	23	177	199	177	200	0.95
5	11	1.8e-06	0.00015	22.5	0.9	1	23	207	229	207	229	0.97
6	11	0.0081	0.66	11.0	1.0	1	23	235	258	235	259	0.95
7	11	0.046	3.7	8.6	0.1	2	23	265	286	264	286	0.96
8	11	2.4e-05	0.002	18.9	2.7	1	23	292	314	292	314	0.98
9	11	2.2e-05	0.0018	19.1	4.7	1	23	320	342	320	342	0.99
10	11	0.0028	0.23	12.5	1.3	1	23	348	373	348	373	0.95
11	11	0.00067	0.055	14.4	0.0	1	20	379	398	379	400	0.95

Sequence Information

Coding Sequence: ATGGTACGCAGCCGTCGCAGCCTCTCCAAGGAGGATGCCGTCTCTTTGCTCACGGATAGCGGCATCTCGCTGTCATCGCCGCCGGCGGCACGCGAATCCTCGCCCGCAGCGACACCCATCAAGCGGCGCAAGAGCAGCCTTAACAGTCTGCAGGATTTGTATGTGGATGACGAGCTCGAGGCCGAGCAGGACTCCACAGACGCAGATGCTGACTACATACAGCCGGAGCCTAAGAAATCCCCACGCAAATCGGACTCAGCGCGACGCAAGAATCATGTGTGCAATCATTGCTCCAAGGAATTTGGTGGCCGGACCGATCTGTTGCGTCACATGCTCATCCACTCGGACGAGCGACCACACAAGTGCACAGAGTGCGGCAAAAGCTATCGGCAGGCGGTGAATTTGAAGAATCACATCACCACCGCACACGAGCACAAGAAACAGTTCGCCTGCACGGAGTGTCCCAAATCATTTGCACTCAAGGAGCGTCTAAAGCTGCACATGCGACTGCATTCAGGAGAGAAGCCATATCCATGTGCTCTATGCGAGAAACGCTTTGCCCGTGGGGGTCAGttgcaacagcaCATGGTGTCGCATCATAAGACGAGCATACAGCAATTCAACTGCACCAAATGCTCAGCCAGTTTCTCGACCAATGCCAATCTGCGCGTGCATATGGAACGCCACGAGCAGGGCATGGAGCACAGATGCTCCATTTGCGAGAGTCAGTTTGCCAATGAATTAGCGCTGCGCGCCCATATTAACCAGGAGCACCACAAGTTGAGTCAACTCGAGTGCGAAGTTTGCCACAAGGATATTGAACCGGACGAGGATCTGGCCACGCATATGCAGAAGCATGCTGCAGTCAAGACGCACGTCTGTGAGGTGTGCAATTCCTATTTCACACAAAAATCGCAATACAATGTGCACATGCGCATGCACACAGGCGAGCGGCCATATCAGTGTCGGATCTGTCATCAAACATTTGCCCACTCCAGCGTGCTGAAGCTGCACATACGCAAGCACACAGGCGAGAAACCGTTTCGCTGCCAGCTTTGTACGGATGAGGTGGCTTTCTCGCAGCTGGCGCATCTCAAGAATCACATGAAGAAGATACACAACCAACTGAAGCCCTACATGTGCCCTGGATGCCAGGAGTTCTTCAAGATCAAGGTGGAGCTGCAGGCGCATATTGAGCTATGTAGCAAGTGTCAACCATCGGACGAGCTCGAAGAAGGTCAAACAGAAGATGCACTGACGCTATCCAGCATACGCTTTAATATGGCCGTGGTGCTCAAGAAGATTACCTCGGCGCAGAAGCTGCGTCAGCTGGGCTATGAGAAGCGTCTAATTGATAATGTCATCATTGCCTCATTGAAGCTGGCACAGCGTCCGACGCATGATGATGTAACGCAAAACCCTTTGACCAGGCTGCGTTTGAATGTGGAGGAGTTTCTTAAGTGGATTGTGCCGGCGCCCGCCATGCAAAAGTTCAACGAGGAGCTGCTCTCCATCGATACGATACTCGATAAGATTGCGACCATGTACATGAAGCAAAAGTAA
Protein Sequence: MVRSRRSLSKEDAVSLLTDSGISLSSPPAARESSPAATPIKRRKSSLNSLQDLYVDDELEAEQDSTDADADYIQPEPKKSPRKSDSARRKNHVCNHCSKEFGGRTDLLRHMLIHSDERPHKCTECGKSYRQAVNLKNHITTAHEHKKQFACTECPKSFALKERLKLHMRLHSGEKPYPCALCEKRFARGGQLQQHMVSHHKTSIQQFNCTKCSASFSTNANLRVHMERHEQGMEHRCSICESQFANELALRAHINQEHHKLSQLECEVCHKDIEPDEDLATHMQKHAAVKTHVCEVCNSYFTQKSQYNVHMRMHTGERPYQCRICHQTFAHSSVLKLHIRKHTGEKPFRCQLCTDEVAFSQLAHLKNHMKKIHNQLKPYMCPGCQEFFKIKVELQAHIELCSKCQPSDELEEGQTEDALTLSSIRFNMAVVLKKITSAQKLRQLGYEKRLIDNVIIASLKLAQRPTHDDVTQNPLTRLRLNVEEFLKWIVPAPAMQKFNEELLSIDTILDKIATMYMKQK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01324297;
90% Identity: iTF_00534722;
80% Identity: -