Hcon009444.1
Basic Information
- Insect
- Hirtodrosophila confusa
- Gene Symbol
- -
- Assembly
- GCA_035043065.1
- Location
- JAWNNI010000148.1:8731706-8733981[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 1.5e-05 0.0013 19.6 0.7 2 23 92 113 91 113 0.97 2 15 0.00037 0.031 15.2 3.3 1 23 119 141 119 141 0.96 3 15 0.017 1.4 10.0 2.6 2 23 148 169 147 169 0.97 4 15 2.5 2e+02 3.2 0.8 1 15 175 189 175 190 0.83 5 15 0.0029 0.24 12.4 0.1 2 23 193 214 192 214 0.97 6 15 0.00017 0.014 16.3 1.6 1 21 220 240 220 250 0.96 7 15 0.00022 0.018 15.9 0.3 1 20 460 479 460 480 0.95 8 15 0.00097 0.079 13.9 7.6 1 23 494 516 494 516 0.98 9 15 1.1e-06 9.4e-05 23.1 1.4 1 23 522 544 522 544 0.97 10 15 2.6e-05 0.0022 18.8 2.6 1 23 550 572 550 572 0.99 11 15 6.1e-07 5e-05 24.0 2.7 1 23 582 604 582 604 0.98 12 15 0.00016 0.013 16.4 6.4 1 21 610 630 610 632 0.96 13 15 5.7e-07 4.7e-05 24.1 3.2 1 23 638 660 638 660 0.98 14 15 0.00026 0.021 15.7 4.1 2 23 667 688 666 688 0.97 15 15 0.00016 0.013 16.4 1.8 1 23 694 716 694 716 0.97
Sequence Information
- Coding Sequence
- atGAGTGCGGCAATAGATCTGAGTTGCGTGAAAATAGAGAGGGAGCAAGAGCACAAGACGATGGAGAGAGCATCAGTTGTGATGAACGCTTCCAGCGTTGCGTTGCAAAGCGAACATAACTTGACGGAGATGGACATAGGACCTATTAAGATTGAACCGGGCATATCTACAGCGTACCAGAGCAAAGGGGTGGTCAACAACAGCGCGGGACAGCGTAAGAAGCTGGTGCCCGCAGCTCCAAGAAAAAGCGTCCGTGCTACCAAACGGCCCAACCAATGTCCCCACTGCCCACGGTATTTTGAGCGGAAGGATGAGCTtgagatacacacacagattCACACCGATAATCTGCCCTACAAGTGTTCCTTTTGCCCCATAAGTTTCTCTCATAAATCGGTTTACACACAACACATGTTCGGACATACTGGTAAATTTCCTCAAATGTGCTCCGAATGTCCGAAGGGCTTTCTGAAGACTTGCGATCTGAGGAAGCATCTACAAACTCATACAGACAAGACGCCATACATATGTCCGCTATGCCCAAAAGACTGCATACATACGGGCAATTATCCTCTACAGTGCCCCAAATGTCCTCGAGGCTTTATGAAGGGCTTTGAGCTAGAAATACATCTTCAGATTCATAGCGATAGACTTCCTTATAAATGTCCTCATTGCCCGATCAGCTTTGCGCACATTGCGAATTACAGAGCGCACCTTTTACGATGTGATCTCAATAAACATAGGCGGACTCTTACCAAGCCTCGTCCCAGTCCCAAAAAAAGTACCCAGACCTCGAAGTCTACGTTAAAAAGTCAACCACAAGAAAAGCCAGAGGAAATTATAGACATTaggtatataaaaaaagagaaggaGCAGGAGGTAACCGAATCCCCCTCTAAGACCTCGAAGTCTACGTTAAAAAGTCAACCACAAGAAAAGCCAGAGGAAATTATAGACATTaggtatataaaaaaagagaaggaGCAGGAGGTAACCGAATCCCCCTCTAAAGCTGCAGCCAATACGGCGCAGCAAATTGTAGCTTTAGACCGCATTAAACTAGAACAGGAACAGGAGGTAAACGAAGCCCTTGAAAATCCCTCTACCGTTAAGTTCAAAGCATCGGGCATTACGGCGATTAACAAGCGCGCCGAAGAGCTATTGCAGCAAATTATAAATCAAGACTGTATCAAAGTAGAGCCGGATCAGGAGGAAATCTTAGCGACAACGTattcaaaaagcaaaaacagtGATAAGCATGACGGAGAAGATCCACTCCCCGATAGCATCAAAGACGTGAAATCTATTAAATTAGAACCAGAGGAGAGCAAGTCAGATGAGGAGCTCTTAATACTAAGTGATAGCTCAGAGCGGTCCTACAAGTGTAAGATATGCAGCAAGGCATTCTCTGACATAAATGAGCTGCGTTTGCACGAAAAAtgctacacacacacgagcaggCACATGGGCATTCGTCCATATAAATGTAATCACTGCTCGAAGACCTTTACCAAGATTTGCAGTCTAACCGTGCACAAACGCTTACATACCGGCGAACGGCCATTCAATTGTCCTCACTGTCCACGGACTTTCATGCAGAATTCGGGTCTCAAGGTGCACATTCGGCAACATTCCGGCGAACGGCCATACAAATGCCCCCAGTGCCCGCGTACTTTTGTCAACATCTCAAATTGCAAGAAACATCTAAGAGTTCATGGGATCGACGATTCCAGCGATCATCCTTACAAGTGTCCGCATTGTCCCAAAACCTTTCCACAAAACTCTCATTTCCTGGTCCATGTCCGCGGGCACACCGGCGAACGTCCCTATCAATGCACATACTGCTCGAAAGCTTTTAAAGTTAGTCatgatttaaaaaaacacCTTAGGTGCCACACTGGCGAGCGGCCCTTTGAGTGTCCTCATTGTCCAAAAACCTTTGCTCAAAACTCACATTTTAATATGCACTTACGCGGACACTCTACTGAGCGTTCCATTCGCTGCCCTCACTGCCCCCGCACCTTCCTAAAAAGCTACAATCTTAAGGTTCATCTCTGCACCCATACAGGAGAACGTCCTTTCAAGTGTCCCGACTGCCCGAGAACCTTTACTCAAAACTCCATTTGCCAAGCCCATATGCGTGAACATTCGAAATGA
- Protein Sequence
- MSAAIDLSCVKIEREQEHKTMERASVVMNASSVALQSEHNLTEMDIGPIKIEPGISTAYQSKGVVNNSAGQRKKLVPAAPRKSVRATKRPNQCPHCPRYFERKDELEIHTQIHTDNLPYKCSFCPISFSHKSVYTQHMFGHTGKFPQMCSECPKGFLKTCDLRKHLQTHTDKTPYICPLCPKDCIHTGNYPLQCPKCPRGFMKGFELEIHLQIHSDRLPYKCPHCPISFAHIANYRAHLLRCDLNKHRRTLTKPRPSPKKSTQTSKSTLKSQPQEKPEEIIDIRYIKKEKEQEVTESPSKTSKSTLKSQPQEKPEEIIDIRYIKKEKEQEVTESPSKAAANTAQQIVALDRIKLEQEQEVNEALENPSTVKFKASGITAINKRAEELLQQIINQDCIKVEPDQEEILATTYSKSKNSDKHDGEDPLPDSIKDVKSIKLEPEESKSDEELLILSDSSERSYKCKICSKAFSDINELRLHEKCYTHTSRHMGIRPYKCNHCSKTFTKICSLTVHKRLHTGERPFNCPHCPRTFMQNSGLKVHIRQHSGERPYKCPQCPRTFVNISNCKKHLRVHGIDDSSDHPYKCPHCPKTFPQNSHFLVHVRGHTGERPYQCTYCSKAFKVSHDLKKHLRCHTGERPFECPHCPKTFAQNSHFNMHLRGHSTERSIRCPHCPRTFLKSYNLKVHLCTHTGERPFKCPDCPRTFTQNSICQAHMREHSK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -