Basic Information

Insect: Hirtodrosophila alboralis
Gene Symbol: ken1
Assembly: GCA_035043045.1
Location: JAWNNH010000327.1:20336-22756[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.074 5.1 7.9 5.9 3 23 257 277 255 277 0.96

2 12 0.00072 0.05 14.2 0.5 1 23 283 308 283 308 0.94

3 12 0.00095 0.066 13.8 1.1 1 23 315 340 315 340 0.93

4 12 0.001 0.071 13.7 4.0 1 23 350 372 350 372 0.97

5 12 0.0021 0.14 12.8 2.2 1 23 379 401 379 401 0.97

6 12 0.008 0.55 10.9 0.5 1 23 407 429 407 429 0.97

7 12 0.028 2 9.2 3.3 1 23 435 458 435 458 0.97

8 12 0.021 1.5 9.6 4.1 1 23 464 486 464 486 0.95

9 12 0.0093 0.64 10.7 2.7 2 23 493 514 492 514 0.96

10 12 0.0002 0.014 15.9 0.8 1 23 609 632 609 632 0.95

11 12 0.00041 0.028 15.0 0.8 1 23 638 660 638 660 0.95

12 12 1.1e-05 0.00075 19.9 2.3 1 23 666 688 666 688 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.074	5.1	7.9	5.9	3	23	257	277	255	277	0.96
2	12	0.00072	0.05	14.2	0.5	1	23	283	308	283	308	0.94
3	12	0.00095	0.066	13.8	1.1	1	23	315	340	315	340	0.93
4	12	0.001	0.071	13.7	4.0	1	23	350	372	350	372	0.97
5	12	0.0021	0.14	12.8	2.2	1	23	379	401	379	401	0.97
6	12	0.008	0.55	10.9	0.5	1	23	407	429	407	429	0.97
7	12	0.028	2	9.2	3.3	1	23	435	458	435	458	0.97
8	12	0.021	1.5	9.6	4.1	1	23	464	486	464	486	0.95
9	12	0.0093	0.64	10.7	2.7	2	23	493	514	492	514	0.96
10	12	0.0002	0.014	15.9	0.8	1	23	609	632	609	632	0.95
11	12	0.00041	0.028	15.0	0.8	1	23	638	660	638	660	0.95
12	12	1.1e-05	0.00075	19.9	2.3	1	23	666	688	666	688	0.98

Sequence Information

Coding Sequence: atgAATGAGGGGAGTGAATACTCCATACACTCGATATGCCGCATTTGCCTGAACCATTTGCGTAGCGATGCAGCGTACGATCTATTTCTCGTTCCGGGTCTGGCCAAGAAACTCTGTGTCTGCACTTCACTCTCGGTGGAACAGCACGATGGCTTCCCGAAAAACCTTTGCACCGCTTGCTACACCAAACTGGACGATTTGCATGCATTTCAAAAGGTCTGTGTGGACTCGGTCCAAAAGTTTCAGGATATGGTTGCCAACAATTATTTCCAATCGAACATTGCGgatattaatcaaattgacAATGTTGATGTACTCAATATTGCTGTGCAGGATGGCGAAATGGAGGAGGATCGCATCAATTTTGATCCActtttaaataccaaaatcGAGATCATTGAGAATGAGGAGgatgtttttaaaatgctaGAAGATGTTGACAAAGAACCCGATGAGGTGGAGAAGGTATCTTCCAGTGATGGCAACGACAGCGACAACgacaatgataatgatgatgatgtggacTTTGAGGCAAATAGCAGCGATTCAGATGACGCTATGCCCTTGGCACGATTGCGTAGTACCAGATCAGCAAAGGCAAAGCCCAAAAAATCTacaaatgatgatgatgatgacgatgatgacaacgatgatgatgataccTCTAGCTCAGATTCAGATGATGAAGTTACGAAGCCTAAATCGAAATCTAAACCAAAACGTAAACGCATTCCAGCCGCTGAACGTCAtctgcataaattaattgattgccACATTTGtcatcaaaaattcaaaaaagcaATTCGCTACGAGGAGCACATGAAACATCATAACGATCTGTTGCCATTCCAGTGTACTGTCGAAACCTGCCGGAAGGGTTTCACAACAGCCGGTGGTCTACGTCTTCATATGGACCATGCACATTCAGAATTCTCCGAGGTGCACGCCTGCACCTTTGAGGGCTGTGGCAAGACATTCCCACGCTCCGTTTTGCTTACGTTCCATATGAAGAAAGTGCATAAAGTTGCCAAACCCGAAACACGCAAGCATCCCTGCACTGAATGCGAGAAAGTGTTCCGTTGCCCCACAGCGCTCAagaaacatatgtataaacacACGGGCGAGGAGTTGCCTTTTGCTTGcgaaatttgtggcaaacgCTTCCATATACACAGTGTACTAAGAGATCATCTGTTGCGGCATGCGGGCGTTAAAAATCACGTTTGTCCCTATTGTGGCGTGGGCAAAACCACTCGACAGGAGTGGAATAAGCACATCTTGACCCATACCAAGGAAAAGCAATACCAGTGTCGTCAATGCGATCACTCCTCACACAACAAACAGGCGTTGTCCAATCATGTCAAGGTCGTACAcatgaaaattaagaatttcgCTTGTCAATATTGTGGCAAGACATTTGGCAAATCGCATGCTTGCAAGATTCACGAGAGACTTCACACTGGCGAGAATTGTTGCGAGTGCAAGATCTGTGGCAAGATCTTCCTCTTCGAAAAGCGCTTAACCAAGCATTTGAAGATACACGAAAAGCGCGAAAATGCACCACCTGCCGCGACCGCTGTTAAACCGCAAGAAGGAGAAACGCAGCAGAATCCACAGGCGATTATTGGTCAGGAGTTGCAAGAGCCGTTGGACGTAAAACCTTTGCCACCACCAGCACCAGTTATTCCTCCCAAACCGAAGAGTTCGCATAGAGTCGAGCGTGTTGATATTTCCCAACTGGCAGGCACCTCTGTCAATCCCATATCATCAGTATCGGTACCTTCCTGGTCGCCTCAAGTCAACTTCACCAAGAAGGAAGGCCAACATATTTGTCCGGGCTGTGGACGTGGCTTTAATCACATTGGCAATATGAAACTTCACTATAAGATCATACACGAAAAGGTCAAGGATTTCGCCTGTCGCTATTGTCCCAAGCGTTTCGCCAAGGCGCAGTATTTGCGCAATCATGAATATATACACACGGGTGAAAAGCCGTTTGAATGCAAGATATGCGGCAAGCACTTCAGGCAGGAACAAGTCTTAAAAACGCATTTGAAGGTGCACGACAAGCCACCGAAGCCGCCAAAGGAAAAGAAACCGCCAAAACCGCAACCCAGCAAATCGCGGGGATTAAAGGTTGAGCTGAATAAAGACAAACCAAAGATTTTTGATGAATTTCAGGATCCTGCGGCAGAACGTGCTGCAGCTACAGCTGCCTTGTTGGCTCAACAGATGGAGGAGAATGAGGCAAAGCGTAAGGCGGAGGAGGCAACTCGCAAGATTCAAGAGGCCGCCTGTGAGCAACTCAATAGACTTGAGAAGCAAATTCAAAGTGAAAAGGGCAATTATGATAGCTATTATGGACAGAAAATTGAAGCCGATGGCACTTCACTGGATGCTCTCAAATTAGATCACGTATAA
Protein Sequence: MNEGSEYSIHSICRICLNHLRSDAAYDLFLVPGLAKKLCVCTSLSVEQHDGFPKNLCTACYTKLDDLHAFQKVCVDSVQKFQDMVANNYFQSNIADINQIDNVDVLNIAVQDGEMEEDRINFDPLLNTKIEIIENEEDVFKMLEDVDKEPDEVEKVSSSDGNDSDNDNDNDDDVDFEANSSDSDDAMPLARLRSTRSAKAKPKKSTNDDDDDDDDNDDDDTSSSDSDDEVTKPKSKSKPKRKRIPAAERHLHKLIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCTVETCRKGFTTAGGLRLHMDHAHSEFSEVHACTFEGCGKTFPRSVLLTFHMKKVHKVAKPETRKHPCTECEKVFRCPTALKKHMYKHTGEELPFACEICGKRFHIHSVLRDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTKEKQYQCRQCDHSSHNKQALSNHVKVVHMKIKNFACQYCGKTFGKSHACKIHERLHTGENCCECKICGKIFLFEKRLTKHLKIHEKRENAPPAATAVKPQEGETQQNPQAIIGQELQEPLDVKPLPPPAPVIPPKPKSSHRVERVDISQLAGTSVNPISSVSVPSWSPQVNFTKKEGQHICPGCGRGFNHIGNMKLHYKIIHEKVKDFACRYCPKRFAKAQYLRNHEYIHTGEKPFECKICGKHFRQEQVLKTHLKVHDKPPKPPKEKKPPKPQPSKSRGLKVELNKDKPKIFDEFQDPAAERAAATAALLAQQMEENEAKRKAEEATRKIQEAACEQLNRLEKQIQSEKGNYDSYYGQKIEADGTSLDALKLDHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610124;
90% Identity: iTF_00805424; iTF_00803842;
80% Identity: -