Basic Information

Insect: Hirtodrosophila alboralis
Gene Symbol: zfh1
Assembly: GCA_035043045.1
Location: JAWNNH010000653.1:208551-239434[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.019 1.3 9.7 1.3 2 23 76 98 75 98 0.94

2 9 0.0014 0.097 13.3 0.1 1 23 281 303 281 303 0.97

3 9 3.3e-05 0.0023 18.4 1.8 2 23 317 338 316 338 0.97

4 9 0.00023 0.016 15.8 8.0 1 23 347 369 347 369 0.99

5 9 0.00022 0.015 15.8 1.8 1 21 375 395 375 396 0.94

6 9 0.031 2.1 9.1 0.4 2 21 638 657 637 658 0.92

7 9 1.5e-05 0.0011 19.5 0.5 1 23 1003 1025 1003 1025 0.94

8 9 5.8e-05 0.004 17.7 7.4 1 23 1031 1053 1031 1053 0.98

9 9 0.0026 0.18 12.4 4.4 1 21 1059 1079 1059 1080 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.019	1.3	9.7	1.3	2	23	76	98	75	98	0.94
2	9	0.0014	0.097	13.3	0.1	1	23	281	303	281	303	0.97
3	9	3.3e-05	0.0023	18.4	1.8	2	23	317	338	316	338	0.97
4	9	0.00023	0.016	15.8	8.0	1	23	347	369	347	369	0.99
5	9	0.00022	0.015	15.8	1.8	1	21	375	395	375	396	0.94
6	9	0.031	2.1	9.1	0.4	2	21	638	657	637	658	0.92
7	9	1.5e-05	0.0011	19.5	0.5	1	23	1003	1025	1003	1025	0.94
8	9	5.8e-05	0.004	17.7	7.4	1	23	1031	1053	1031	1053	0.98
9	9	0.0026	0.18	12.4	4.4	1	21	1059	1079	1059	1080	0.96

Sequence Information

Coding Sequence: ATGTTGTCCTGTTTGCCGCCATCGTCTACACGTTTTGGCCAAGAGGATAACATTATACAGCAGAGCATGCCATCGTCCACAGCCTTCTCCATGCAGTTTCCCGCTCTGGCCTCCAGTTTGCACCATCATCAAGCACACAGCAAGCCCAACAATGTGGCTGCAAATCAGGAGCATGCCACGCATGCGGCCAGCGCCACAGCGAGTGCAGCCGATGATATTCTGGTCAAGTGCACGCAGTGCCACAAGCGCTTCAATGAGTTTCAGTCCCTTGGCGAGCATATTGCCAGCGAGCATCCGCATGACAAGCTCAATTATGAGCCGCATCGTGCCACAGGCGCGGCACAGCCCGAAAGTGAAGCGGAGGAGGATGAGCGTAGCAAtttaagcagcagcagtcgccgCTATACAAAGTCCCCaaccaataacaacaataacaacaacaacagcgataCAGCAAAGAATCAAAATAACAGCCATAGAAATCAACACTCACCATTGTGCTCACCTGTTGCCCAGGCGTCCAGCGATTTGTTTACTCACCTGCCACATCCACCGACGCATTTGCCCGCCCAGTTGCATGCACAATTTATGGCCGCCGCTGCCTTGGCCATGCAATCCGCACGCTCCGCCAGCTCACCCAGCcaacagcaccagcagcatcagcagcaacaacaccagcaacaacagcagcagcaacaacacgcacaacagcaactgttgccgCCACCGCTACCGGGCAGCAATAGCAGCGTTGGCAGCAATTCCGCCTATGATCTAGACCTGAGTGCACCCCGTTCCACCTCCAGTCCCGGCTCTACAACGGGCGATCTCAACGCCGCCTTCCCCTGCATGCAGTGCACCGCAGCCTTTGCCAGTCGGGAGCAATTGGAGCAGCATCAGCTGTTGCACTCGCCCACGGGCCAGCAGACCACGCAGAATGTGACCCAGacCTGTAAAATTTGCCATAAGGCATTTGCCAATGTTTACCGCCTGCAGCGTCACATGATCAGCCACGATGAATCGGAGCTGCTGCGGAAGTTTAAGTGCAATCTGTGCACCAAGGCCTTCAAGTTCAAGCATCATCTGAAGGAACATAAGCGCATCCATTCCGGCGAGAAGCCCTTTGCCTGCAATAAATGCGATAGACGATTCTCGCACTCGGGCAGCTTCTCCTCACACATGACATCCAAGAAGTGTATTAATATGAATCAAAAGCTGAATAATAATCGTCAAACAACGGATAAAAATTCAAACGCTGGACGCTCACCAacgcatcagcagcagcagcagcatcaacagcagcagcagcaacagcagcaactgctgaGTGGCAAGCGTGCTGCCTGCAAGTTGCCGGAGCAAGTGCTGCCAAATCCTATGAATTATTTTGCAGGAGATGCAGCACAGTTGCCTGCGGCTGCAGCAAATGGTGCTGCATCGTTTTATCCCAATTATAGGGCCATGAATGCGGCCTTGTTGGCATTTCCCAATGCCTTTATGGCCGCAGCGCTGGATCCACGCATACATCCCTATAGCATACAGCGATTGCTGGAACTAACAGCTGCcgggcagcaacagcagcagcagcaccaacagcGTGAGGAGCATCAtcagcaggagcaacagccGCTTTTTGAGCTCGCcaaggatgaggatgagaCGCCAGATGAGCCAAAATTAGTTATGGATCTGGAAGAAACGGAGATCAAGGCTGTGGCAACACCAGATATGCCCGCAGTTGAGACAACAGCCGATGCTGCCTCAGTTAAGCATGAGGCAAGCCGTGAGCCAACTCCCGCGCTGCTGCACAGTGCACCCGATACGCCCAAGTCCATTAAAATGGAACAAGATGAGGAAATGACGCCTGTGGAGGAGCACACGCCACACACTCAGCCAACAGCCAATGAATTGCGTTGCAGTCGCTGTGCCAAACAATTTAATCATCCCACAGAGCTGGTGCAGCACGAGAAAGTGCTATGCGGACTCATCAAGGAGGAACTGGAGCAACActaccaacagcaacaacaacaacagcagcagcaacaacaatccaACTTTGTATTGCCCTCGGCCAGCGATGCCGACGAGgatgatgaggaggaggagccACGTCAGGATTATAACGCtggcagcagcgacagcggcgAGCGTAAAGTGCGTGTACGCACCGCCATCAatgaggagcagcagcagcagctgaagcAACATTATGCCCACAATGCACGTCCCAGTCGGGATGAGTTTCGTCTGATTGCCGCTCGACTGCAGCTGGATGCACGCGTCGTCCAGGTCTGGTTCCAAAATAATCGTTCGCGGGAACGCAAGCTGCAGAGCTAtgtcagcagcagcggcagctgtgAGCCAACAATGGACACAGCAGCGCCAGCTCAACCACGCGCTGCTGGCGAGGATCAGCCCCTGGATTTGTCCGTTAAACGCGATGCATCGCCGTTGTATGGCCTGGCGCCGCAACAGGCGGCAGTTGGGGCAAGTCAAGCGCCCGCTGATTTTCAGGAGACCATGGCCATAAATCTTAGCCGCAAGTTGTCCAGCTCGGTGTCCATGTCGCCTGCTTCGTTGTCGCCCTGCTCGGGTGCCTCCTCGTTGCAGCAaacggcagctgctgctgccgctgcggcGCTTTATTTTGCGCCCCCCTCACCACCCAGCATGCACGATGCGGCGCCACCAATGCCACCACATAGCGCTGCCACACGTGGTCATCCATTTCCGGGGCTGCCGCCTTACATGATGCCACGCCTGCCCATGGAGGCGCTCTTTCAGATGCGACCCGGCGGCGATTATGCGCCCAATCCGCTCATGAACAGTATTAATCGCGGCACCAGCCTCAGTCCGGGCGGTTCCGAGAAACGCTCGTGGCGTGACGATGATTCACGCATCTCGCATGAGGATGACTATGTTCTGGCCGGCGCTGGACTGCTGCCACCCAAGCCCAGGCGAGCCAAGGCCGAAACGCACGGACATGCGGGCGATCCGGATTTGCCCTTCGTTTGCGATCAGTGCGACAAGGCGTTTGCCAAGCAGAGCTCCCTGGCACGCCACAAATATGAGCATTCCGgtCAGCGACCCTATCAGTGCATGGACTGCCCCAAGGCCTTCAAGCACAAGCATCATTTGACGGAACACAAGCGTTTGCATTCCGGAGAGAAGCCATTTCAGTGCACCAAGTGCTTGAAACGCTTCTCGCATTCGGGCAGCTACAGTCAGCACATGAACCACCGCTACTCCTACTGCAAGCCATATAGGGAATAG
Protein Sequence: MLSCLPPSSTRFGQEDNIIQQSMPSSTAFSMQFPALASSLHHHQAHSKPNNVAANQEHATHAASATASAADDILVKCTQCHKRFNEFQSLGEHIASEHPHDKLNYEPHRATGAAQPESEAEEDERSNLSSSSRRYTKSPTNNNNNNNNSDTAKNQNNSHRNQHSPLCSPVAQASSDLFTHLPHPPTHLPAQLHAQFMAAAALAMQSARSASSPSQQHQQHQQQQHQQQQQQQQHAQQQLLPPPLPGSNSSVGSNSAYDLDLSAPRSTSSPGSTTGDLNAAFPCMQCTAAFASREQLEQHQLLHSPTGQQTTQNVTQTCKICHKAFANVYRLQRHMISHDESELLRKFKCNLCTKAFKFKHHLKEHKRIHSGEKPFACNKCDRRFSHSGSFSSHMTSKKCINMNQKLNNNRQTTDKNSNAGRSPTHQQQQQHQQQQQQQQQLLSGKRAACKLPEQVLPNPMNYFAGDAAQLPAAAANGAASFYPNYRAMNAALLAFPNAFMAAALDPRIHPYSIQRLLELTAAGQQQQQQHQQREEHHQQEQQPLFELAKDEDETPDEPKLVMDLEETEIKAVATPDMPAVETTADAASVKHEASREPTPALLHSAPDTPKSIKMEQDEEMTPVEEHTPHTQPTANELRCSRCAKQFNHPTELVQHEKVLCGLIKEELEQHYQQQQQQQQQQQQSNFVLPSASDADEDDEEEEPRQDYNAGSSDSGERKVRVRTAINEEQQQQLKQHYAHNARPSRDEFRLIAARLQLDARVVQVWFQNNRSRERKLQSYVSSSGSCEPTMDTAAPAQPRAAGEDQPLDLSVKRDASPLYGLAPQQAAVGASQAPADFQETMAINLSRKLSSSVSMSPASLSPCSGASSLQQTAAAAAAAALYFAPPSPPSMHDAAPPMPPHSAATRGHPFPGLPPYMMPRLPMEALFQMRPGGDYAPNPLMNSINRGTSLSPGGSEKRSWRDDDSRISHEDDYVLAGAGLLPPKPRRAKAETHGHAGDPDLPFVCDQCDKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCTKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00530857;
90% Identity: iTF_00802741;
80% Identity: iTF_00802741;