Halb007720.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Hirtodrosophila alboralis
Gene Symbol
hang
Assembly
GCA_035043045.1
Location
JAWNNH010000264.1:89235-109800[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.39 27 5.6 1.0 3 23 515 536 514 536 0.93
2 18 0.28 19 6.1 3.5 3 22 643 662 641 662 0.89
3 18 0.00083 0.057 14.0 3.3 1 22 766 787 766 789 0.90
4 18 0.1 7.1 7.4 0.1 2 21 801 820 800 821 0.93
5 18 0.00096 0.066 13.8 0.2 2 23 954 976 953 976 0.95
6 18 0.0028 0.19 12.4 0.1 1 23 984 1007 984 1007 0.96
7 18 2.2e-05 0.0015 18.9 0.1 2 23 1093 1114 1092 1114 0.97
8 18 0.0004 0.027 15.0 2.9 2 23 1230 1252 1229 1252 0.97
9 18 0.031 2.1 9.1 0.2 2 23 1261 1283 1260 1283 0.95
10 18 0.003 0.21 12.3 0.1 1 23 1296 1319 1296 1319 0.97
11 18 0.00017 0.012 16.2 1.1 1 23 1366 1388 1366 1388 0.99
12 18 0.0027 0.19 12.4 0.9 1 23 1396 1419 1396 1419 0.96
13 18 0.084 5.8 7.7 0.5 2 20 1427 1445 1427 1445 0.95
14 18 9.9e-05 0.0069 16.9 0.4 3 23 1537 1557 1536 1557 0.98
15 18 0.007 0.48 11.1 0.1 1 23 1592 1614 1592 1614 0.97
16 18 0.00082 0.056 14.0 0.6 2 23 1702 1724 1701 1724 0.93
17 18 0.0091 0.63 10.7 0.4 3 23 1780 1800 1780 1800 0.98
18 18 9.3e-05 0.0064 17.0 2.1 1 23 2200 2222 2200 2222 0.99

Sequence Information

Coding Sequence
ATGTGTGacgctgcagcaacaacaatatcagcCATTGGTCATGGAGCTGGAGCAATGGAGGAACTAAATCAGCGAATGCGTCAAAGGTGCTGTCGTTTATGCATTGCACCCGCCAGCGAATGCATTTCGATAATTAACAGTTATGCCGCCGATAAGGAGCCGCTGGCcattaaaatacataactGCGTAAATATCAAGATCTCAGCAGTGGATCGTCTATCGCTGCATATTTGCCATGCCTGCATCAGCTATTTAAACTCTTGGCAGAGCTTCAAGAATCGCTGCCTCAGCTCCCAGACAAAGCAGCGACAATGGCTGGACACGGACAAAACCAAACAGCAGACACTATTGGGATATTTGGATTTAAACAGGGCCGAGAATGGCAGCAGCGCAGTtgatcaacagcagcagcagcagcaacaacaacaacaacaacagcagcagcagcagcaatctgAATTGAATATTGATTCGACGACAAGTGCAGCTGAGAAGGCGACCGCTACCGCTGTCAACATTTTGGATGGCATACCACAGCTGAAGAAACGCAGATCTTTAACAGTCTATGTGAGTccaaagcaacagcagcagcaacaacaacagcagcaatcagGCAGAACGACAAGCGCGGCGACAGAGCCACAACAAACATTGCAAACCCTTTTATTGCAGGTGCCCTCAACGGCATTGgcaacacagcaacagcaccagcagcagcaacagcatcagcaacagcagcgcaaATATCAACAGCAACGTggcaagcagcaacagcaacatcatcatcattatcaatattatcagcagcagcagcgacagcgacgcaTTCGTCAGCCTGGAAgacgtcagcagcagcagcaccaacaggcagccacaacaacagcaacaacaactgcttCACAGCAGCGTTTAACCAAATTTAAGCCGAAATTGTATTTGCCATTGGATATTTCAGTGCCAGCATTGccgccattgccattgctgcCACCAACGACGCCAACTGTTGCTACTGCtaacgctgctgttgctgaagctgcagctacagctacagctgcagcaacaacattgccATTGCCGTTGTCGTTGCCATTTGATTTtagccaaaatttaaattttaatcagacTCAGAGACACAGCAGCAGCGTGTTGCCGCCGTCGTTGCCATTGCCACCGCCGCCAGTTGCAACAatgaccagcagcagcagtgccgcatctgcatctgcatctgcagccgctgcctctgcctctgccacaATTACGACACCATTGCTTATGCCGACGCTGCCGGCAGTGCCCATCAAGGATGAGCCCATGGACGACACGGACGATGACTTTCAAATGAAGTGCATTGACGAATCCGATGATATGATGGATCCCACAATGTTCCTAGAGCGTTCCGAGCATGAAGGCGATGTGCCTCTAATGACATCCGACTATGATTACACAGCGCAACATGGCGTGACGGCGGCTGTGGCTGCAGCATCGTTGCCTGCCACTGCAGTGGCAAATGTTGCCGCCGCTGGTGACTCCAAGGTGGCCAGCTGTCGTGCCTGTAGTCTGCAGTTCTCGACGCGGGCAAATGCGCGACGCCATGAGCGCAATCTGCATCCGAATCTGTTTCAGTTGTCCACAGATTCACCCAATAATACGCCAATTACAAAGCCAACACCAGCATTGGCTGCCGCACTGGAAATACAACGTGCAgcggccgctgctgccgccacAGCAGAGGCAACAAAAGCCGCTGCTGGTGGCAATATCTCGGCACAAAAGTATCGGCAGGTTGTCATGAATACGTTCATCAAGTGCGAGAATGGCGGCTTTGACTACGACAATCCTGAACAGTATCAGCAGCTGTTGACGCGCGACAAAGTGGAGTTCATTCAGGAGAATAATGAATTTCTGGAACAATATCAGACAATGACCTGTCGTTGTTGCAACAAATTCTTCAGCACCTACAAGAACTTTATGGCACATGTGCGCAAAAAGTATCCGCTCTTGCCGCGCAATTTATGCTTCAATTGCCTCAAAATGAACGATTCGAAGGCGTTGTTCATATCGCATCTAAAGAAGCGCAACTGCATCAATTTGTATCGCATGCTCAACGCTCTGCGTCTCAAGCAGCCAAATTTTGCacatgcaactgcaactggtgGTGTTGCCACTGCTGCAGATATAAGTGCtgggcagcagcaactgttgctgtcgTCGGCAGCAGCGACAACCGCACACGAAACATCAACAACGGAACGGCCAGAGAAACTGCGCGCCAAGGAGCTGCTGGTGAATAAGCTATATGAATGTAAACTCTGTCCAAAGGGCTTTCGCACCAAACATGAATTTCGCACTCATGTCTATGATAAGCATGCGGATGTGCAGCGCAAGGATAACAATTCAATACAGTGCAGCTTTTGTGGATTTGATTTTGCCGATCCGGTGGATCGGCGTCGCCACTATAACAATATGGATTGCATTGTCCGTTTGCGCTGTATGACCTGTGATGCCAAATTGGAGACACATCAGCGTTTCCTCGATCATGTCTATCAGGATCATTTGGGCGGTGTGAGCAGCGATAATGCGTCCTCTACAGCAAATAGCAACAATATGGATCAGCATTCACCCGGCAAGCGTAGTTTACTGGGCGCCCTTGGCATTGGTGTCAGTCAATCGTCCAATGATGAAtcgcgcagcagcagcaacaacaataacaacaatgcaacTGGTGCAGCATTTACCTCAACACCCAAACTaatgtcatcatcatcgtcatcaggTGTGGCTGGtggtgcagctgctgcagcgaGCGGCAGTCGTGATGCTGCTGCGCCCAAATCCCAGTATTTCTCACGAATGCCCCAGGTTTGCCCCATCTGTGGCCAACagtacaacaactacaacaatgtGCTGCGACACATGGAATCGAAGCATCCCAATAAACTGCCCGAAACATACAAGTGTGTACGTTGCGGCTTAGGCTATCCACGCATCTCCTACCTGCGCGAGCACATGATCAATGTCCATGGCGTGGACAAGAATCGTCATTCGGGCGGCTTTGAATATATTGTGAATGCGGATGCGGTTAAATTGGCCGATGGCAGCACACCCAATGTATATACTGGACGTTATGATTATGTGATGAAGGATTTAATGTCCATAACAAATGGTGGGACACTCgACGATGACGAGGAGGAGGGCGGCAGCGTTGCCAAAAAGATGCGCCTTGAtgatagcagcaacaacagcagcattaACACCAGCATTGCCAATCAGCAAAAGGAATGCCCCATCTGCAATGCGGTGTTTAGCAACAATATTGGTTTATCCAATCATATGCGTTCACATTATACCGCCTCGACAGCAACAAATGCCGCATTGGCGGCTGCCAATCGTATGACGCCCAAATCTTTAACAATAACCGCAGCACCGCCGCTTGAGGCAGCTGCCACAACGGCGTCGCTGTCAACAAGTAGCGCAACATCAGGCGCGGCAGAAGCAATAGCAACttcgacaacaacaaccacagcaacagttgcagcagcagcggcagcgacaacaacaacaaaaggcacaactgttgctgcaactGGAGGCGGCTTACCGCCCGCGATGGCCCATCAGACACCACAGGAACAAGCTGTATTCCGTCGCAGTCTGGATCAGGCTGCTGATCGTCGGTTTCGCCGGATGCGTTGCCGCATCTGTCAGCGTAGATTTAGTTCAAAGAAATCATATCGCTACCATATGCTAACCGATCATCAGGTGCAGAATGTGCAGTTCATCAAGTGTAAGCTATGTAATGCCGAGTTTGCCTACGAGAAGGGTCTCAAGGTGCATCTGTTTAAGGTGCATGGACGTGCCATTAAGGATGAAATGATTATCAAGCAATTTGAATGCGATGTCTGCTCGATTGTATACAGCTCTGAGCTGGAATTGCAACAGCACAAGCGTAGCGTTCATAAATCCCAACTGGGTGCAGCTGGCGCCGCCAATGATACATTTAAATCATCCTCCAAatctacagctacagctacctCTGCCGCTGATCTGGCCGATACATCGGGtacggcagcaacagcagccttACCCCTCTATTGGTATCAATGCAAGTACTGTCCATCCAACTTTAATACCAACAAAAAACTGGCCATACACATTAATTCGCACGATGAATTCGATTCGAATGATTATTCGTGCAAGGACTGTGGCAATGTGTATAGCGGTCGCAAGAGCCTTTGGGTGCATCGTTATAAGAAGCATCCACAGGTCCCCGATCCCGCTGAGTGTACGCTATGTCGCAAAATGTTCTTTGACCGCCAAATGCTGGAGAATCATCGGCCCACCTGCAATCGTAAGCCAATCACTGCCACTGGCGCCCATCAGCAGGATCACCAGCAATTGCAAACGCAACAACATCATCGCGGCATATTCAAGCACAAGACGGGAGACGATGATGACGaggaggatgatgatgatcagaCGCTGATGATGGATGATGGaggtggtggtggcggtggtggtTCTGGTGCTGGTACTGGTGCCACCGATAGTAGCAATGGAGCAGCGACGAGCAACTCAAGAGCATTGAAGATACGCATACCGGAGGTGGCATGCACCATTTGTGGTGCACGTTTCACCGACCAGGAAATGTTCAGCAAGCATATACAGAAGCATGAACAAGACCTGTATGTGGACGATCCATTGGCAGCCATGTTCGATGATGGTCCAGCAGATGCTGGACAATTTCAGGTGGAGCATCAAAATGAGAATGGCGAATATGCGTGCGATTTGTGCGCCAAGACGTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAATCCCATCATCGACGGCGAAGCGACAATGctgaacaacagcagcaacaacaacaacaactcgcTGAGCAACTCATCGATGTTGCATCTACGCGAACTGCATGCAGTCGGCCTGATGCCCAACCAGCAACatcagaagcaacaacaacagcagcagcagcaacagcaatccCGGAACAACAACTCATCGAACAGTTCATCAACATCGAGAAGCAAATCGATGAAACGGAAACGTGAACTTAAATGCGAATATTGCGCCTCCACGTtcattagcaacaacaatctgCGTCGCCACATGTACGAGCTGCATAAACATGAAGTTAGCAATCTGCCGGAGCCACCAGTGATTGAGGTAGATGAGCCGCTCACCTGCCGCCGTTGCGGTGATCTGCAATTTGAGACAAAGGAACAGTGGATCGAGCATAAATTGCTTGATGCCAAAATTGTGCGTCCATTCTGTCCATTCCAATGGGGCTGTGATCTATGTGGCGAGTATTTGTCGCGTAAGGAGAAGCTCATGAATCACATTAACAATCATCTTAAAGAGGATGTCATTGTGCccgtggcaacaacaacaaaaatcacaacaacTAAAATGCCAGCGCCGTCAGCGTTGATCTATAagaatgcaacaacaacgaaatctaaaatggcagcaacaacaacgacgcgAACGACAACAGTTAAACAATTAAAGGCCAaggataatgataataatgaggTGAAGGTGGCAAAGTTGCAAAAGCGTCGGCATGCGGCAAATGACGCAAGTGTGGAGCAagataataatgaaaatgaaagtgatacgaacgatgatgatgatgaggaagGCGAGGTTGCTACTGATAGTGATGATAACGATGATGATTCAAGCACAAgcgctgatgatgatgacgaggacgatgatgacgatgatgaggacgatgacgacgatgatgatgaagatgacgAGGAAGAAGAAGTTGCTGGccaattgcagcagcagcagcaacaacaacataataatataagcaGCAGCAATTCAATTGgaaatgatgatgacgatgatgatctGATTGAAGAGGTAATCGAGGAGctcgacgatgatgatgatgatgatgaagatgacgAAGACGATGTTGACCCAGGTAATACAACGGATGAGCACCAGCAACAGCCAATAGCCAACCTTAACAAAGAGCAGGCGCAGCCAACACGCTTGAGGAGCTATGAGTACTCGCGAACTGGCAGCGCTGCCAAGttaaatggcaatggcaatggcaaacCGTCCAAGTCAAAGTTGCAGcaatcgcagcagcagcggcaacagcagcagcagcagcagcgtgtGCTAATCGTGCATACCTCtgatgaggaggaggaggaggaagagGATGATATGGATGGTGGGGATGGTGATGGGGATGGGGATGTTGATGATGTAGAGGAGAATGATGATGTGCTGGATGATGATGGCGTGGGTGAAACAATGAACATAGATGATATAATTGAAGAAGATGATGAAgatgacgacgatgacgataatgataatgatgatgatgacaatgaTCGTCGTCGTAGCGATGGTCATGACGGCATTGTCGATGGTGTTGGTGGCGATAGTAATTCGTCATCATCTGATAGCGaatcaacaacatcaacatcatcgaGTTCAACTGGTGAGCGacgtaaacataaaaaaactgtAGTTAAATCAGCGGCACATGGCGCTGCCGCTGATCAGTCTAATTCCAGCTATACGTGTGATCTATGTCAACTTTGTTTCGATTCCCAGGAGCTTCTGCAGACTCACATTAAAAGCCATTTTCTGAATGGGCCAACAACGGtgggcggcggcagcagcagcagcagcagtagtcgcagtcgcagcagcagcagtcgacGAAGTCACAGCAATAGCAGTCGAAGAAGTCACAAcaggggcaacaacaacaacaataacaacagcaaaatcAATACCAAAAAGTCCGGACtggatgcaacaacaacaacaacagcaaaaagtgCAGCAAAAACGAAGCCAATGTCATCAACGACGGcgactgcagcagcaacagataCTGCTAACTGA
Protein Sequence
MCDAAATTISAIGHGAGAMEELNQRMRQRCCRLCIAPASECISIINSYAADKEPLAIKIHNCVNIKISAVDRLSLHICHACISYLNSWQSFKNRCLSSQTKQRQWLDTDKTKQQTLLGYLDLNRAENGSSAVDQQQQQQQQQQQQQQQQQQSELNIDSTTSAAEKATATAVNILDGIPQLKKRRSLTVYVSPKQQQQQQQQQQSGRTTSAATEPQQTLQTLLLQVPSTALATQQQHQQQQQHQQQQRKYQQQRGKQQQQHHHHYQYYQQQQRQRRIRQPGRRQQQQHQQAATTTATTTASQQRLTKFKPKLYLPLDISVPALPPLPLLPPTTPTVATANAAVAEAAATATAAATTLPLPLSLPFDFSQNLNFNQTQRHSSSVLPPSLPLPPPPVATMTSSSSAASASASAAAASASATITTPLLMPTLPAVPIKDEPMDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYTAQHGVTAAVAAASLPATAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISAQKYRQVVMNTFIKCENGGFDYDNPEQYQQLLTRDKVEFIQENNEFLEQYQTMTCRCCNKFFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRMLNALRLKQPNFAHATATGGVATAADISAGQQQLLLSSAAATTAHETSTTERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGFDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASSTANSNNMDQHSPGKRSLLGALGIGVSQSSNDESRSSSNNNNNNATGAAFTSTPKLMSSSSSSGVAGGAAAAASGSRDAAAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDEEEGGSVAKKMRLDDSSNNSSINTSIANQQKECPICNAVFSNNIGLSNHMRSHYTASTATNAALAAANRMTPKSLTITAAPPLEAAATTASLSTSSATSGAAEAIATSTTTTTATVAAAAAATTTTKGTTVAATGGGLPPAMAHQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDVCSIVYSSELELQQHKRSVHKSQLGAAGAANDTFKSSSKSTATATSAADLADTSGTAATAALPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHRPTCNRKPITATGAHQQDHQQLQTQQHHRGIFKHKTGDDDDEEDDDDQTLMMDDGGGGGGGGSGAGTGATDSSNGAATSNSRALKIRIPEVACTICGARFTDQEMFSKHIQKHEQDLYVDDPLAAMFDDGPADAGQFQVEHQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIIDGEATMLNNSSNNNNNSLSNSSMLHLRELHAVGLMPNQQHQKQQQQQQQQQQSRNNNSSNSSSTSRSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLTCRRCGDLQFETKEQWIEHKLLDAKIVRPFCPFQWGCDLCGEYLSRKEKLMNHINNHLKEDVIVPVATTTKITTTKMPAPSALIYKNATTTKSKMAATTTTRTTTVKQLKAKDNDNNEVKVAKLQKRRHAANDASVEQDNNENESDTNDDDDEEGEVATDSDDNDDDSSTSADDDDEDDDDDDEDDDDDDDEDDEEEEVAGQLQQQQQQQHNNISSSNSIGNDDDDDDLIEEVIEELDDDDDDDEDDEDDVDPGNTTDEHQQQPIANLNKEQAQPTRLRSYEYSRTGSAAKLNGNGNGKPSKSKLQQSQQQRQQQQQQQRVLIVHTSDEEEEEEEDDMDGGDGDGDGDVDDVEENDDVLDDDGVGETMNIDDIIEEDDEDDDDDDNDNDDDDNDRRRSDGHDGIVDGVGGDSNSSSSDSESTTSTSSSSTGERRKHKKTVVKSAAHGAAADQSNSSYTCDLCQLCFDSQELLQTHIKSHFLNGPTTVGGGSSSSSSSRSRSSSSRRSHSNSSRRSHNRGNNNNNNNSKINTKKSGLDATTTTTAKSAAKTKPMSSTTATAAATDTAN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-