Basic Information

Insect: Hipparchia semele
Gene Symbol: zfh1
Assembly: GCA_933228835.1
Location: CAKOGE010000086.1:73603-86187[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0068 0.36 11.7 0.9 1 23 81 103 81 103 0.94

2 8 4e-06 0.00021 21.9 0.8 1 23 114 136 114 136 0.98

3 8 5.2e-06 0.00028 21.5 6.0 1 23 145 167 145 167 0.99

4 8 0.00016 0.0084 16.8 1.0 1 21 173 193 173 194 0.95

5 8 0.012 0.64 10.9 0.4 1 21 457 477 457 478 0.93

6 8 1.2e-05 0.00063 20.4 1.1 1 23 778 800 778 800 0.94

7 8 4.1e-05 0.0022 18.7 7.6 1 23 806 828 806 828 0.98

8 8 0.057 3 8.8 7.0 1 21 834 854 834 855 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0068	0.36	11.7	0.9	1	23	81	103	81	103	0.94
2	8	4e-06	0.00021	21.9	0.8	1	23	114	136	114	136	0.98
3	8	5.2e-06	0.00028	21.5	6.0	1	23	145	167	145	167	0.99
4	8	0.00016	0.0084	16.8	1.0	1	21	173	193	173	194	0.95
5	8	0.012	0.64	10.9	0.4	1	21	457	477	457	478	0.93
6	8	1.2e-05	0.00063	20.4	1.1	1	23	778	800	778	800	0.94
7	8	4.1e-05	0.0022	18.7	7.6	1	23	806	828	806	828	0.98
8	8	0.057	3	8.8	7.0	1	21	834	854	834	855	0.96

Sequence Information

Coding Sequence: ATGAAAGTGCATAGCCAGCCTATGGGAGTGGGCGGCTGGTACGAATGCTTGGCGGCCGACTGGCTCGCCGACATGCGGAGTAAGCAGGTGCCCACGTCCACCACCTCGGCCAGGCGGCTGGCGGCCTTAATCCGGCCGCTgtcgggcgcggcgggcgcggggggcgcggcgggcgcggaggGCAAGCCGCCCGAGGAGGAGGAGGAGCGCGCGGGCTCGCCGCTGGGGCCGGGCGGGCCCTACGCCTGCAGCCACTGCCGCGGCTCCTACCCCTCGCGCGACCAGCTCGAGCGCCACGAGACGCTGCACGCGCCCAGCACTCAGGTGGATAACGTCAAATATTCTTGTAAAATATGTCCGAAGAGCTTCGACAACGTTTACCGCCTCCAGCGACATATGATAAGTCACATCGACTGCGCATCAATACGAAAATACAAGTGCAACGATTGTGAGAAAGCGTTCAAGTTCAAACACCATCTTAAAGAACATCTTCGAATACACAGCGGTGAGAAACCCTTCGAATGCGCTAATTGCGGAAAGAAATTTTCCCATTCCGGCTCGTATTCCTCACATATGACTTCCAAGAAGTGTTTGGTTATGAACCTCAAGATGGGAAGGATAAAACCGAATAATCCCGCTCTAAATCCAGACCGAAACGCTTCACGCAAACGAACGAATGCCTTGGTCGCGTCGCAACTGAACAACAACATAGCTTCCAATAACGCTTCGTTTTTACCCATACTTCCTAAATACAACGAGGCAGCAGCTGCGTTTTTTGCATCCATGTCCCCACAAGAAAATAACTTCCACCGTCCACCCCTAGGACAACCGGGAATGAACCCTTTCTACATGCCGCCCGGCATGCCCATGAGTCCGGCCAGCGGTATCGCCCCTTATACATTTCCAGCTTCATTGAGTCAGCTATTTGAGCAATTAGCCTCACAACAGTATCAACAGAGAAAGATGGAGAACCCGAGCCCGAAACAAGAGAATCTAATGGGCCCCAACCCTGAAGATTTAATAGAAGAAGTGATCGAAGAAGACGATAAAAGATCCGAAGGAAGCGCTGAACTGGTGATGGATATCGAGGACGATGACAACGTTTCCATTAAAAAAGAGCACGAAGACCGAGACACTGAACAGATGTTACGGTCTCGTGATTTTGAGAACGTTCCAATTAATAACAATGGGTCTGAAGGCGATCAATCCGgttttaatacaatattaaaatctGTCAATGCGTCGGTGACAAAACACTTTTTTAGAGCAAACATGGAAAGTTTATCTCCAGTCTCGGCGAAAGTTTGCCCTACCGTAGAGTCTCCTCCTGTTCAGCATTTAACGGTGAAAGAAGAGCCTGAGGATCCTCACCGCTGCTTAAAGTGTAATCTAACATTCGATGGCAAGAGTGACCTTTTCGAGCATGAAAAACTATGCGGAAATATGTTTAGAAAGCATGAAGGGCTAGCGGCTCAAGTGGCTGAAACAGTAGCACTTAATAGATTAGAAGCTGAAATGCGGGCATCGATACAAAGTGGAGTGAGTGGGAGTGAAGATGAAGACTATGGTAAAGATGAGCACGAGGATAAAGCATCGTTGCACGACAGTGACAGAAAGATCAGAGTGCGCACGGCGCTGAGTGAAGAACAACAAACAGTGTTGAAAGAGCACTACGCTATAAATCCACGTCCCAATCGGGAAGAATTTAAAAAGATAGCGCAACAAATCGGCCTGGATAATAGGGTTGTACAAGTTTGGTTCCAAAATAATAGAGCCAGAGTACGGAGAATGACGCAAGTGGTCGCAATGTCCGACCAGCCCTTAGATTTATCTACAAAAAAGTCGAGCGCATCCGTCACGTCTAGTCCTTCGCCTTCGCCGCCTTGCAGCATTTCAGTTACACATTCCGATTCCGAAGAAGCCGTTAATTTAAGTCAGAAGTCTTCTCGAAGTACGACGCCGCACCGCTCTCATTACTTAAATACGTACCCACATTCCAATTGTTCTTCCTCTTCGTTTATCGACTTTCGGTTGTCACCCTCACCTGGCGAAATCATAAGTGGGCAGAAAAGGCCAATGTCCCAAAAGATGCCCGTCAACCCCGTGATGCCCATGGATAAGTTACTCCAGTACAACGACATGACGAACGGACGGTCGCCGATTCTCAACATGCACATGTCATCGGAGAAAAGGCACGAATCCAGTCCGCCTTACGATCGGCCGACTTGGGGCGACGATCTACATTTACAAAACGATTACGACGATGAGGCATCAGTacttaaaaaaagtaaactaaAGAACTCAAGCGACTATAAGGAGGGAGAGGGGCAGTTCGTGTGTGACCAGTGCGACAAAACGTTCGTCAAGCAGAGTTCTCTCGCGAGGCATAAATACGAGCACTCAGGTCAGCGGCCGTACAAATGCGCGGAATGCGACAAGGCGTTCAAGCACAAACATCACCTCACGGAGCACAAGCGCCTGCACACGGGCGAGAAGCCTTACCAGTGCTGCAAGTGCCTCAAGAAGTTCTCGCACTCGGGCTCCTACAGCCAGCACATGAACCACAGGTTCGCGATCTGCAAGCCCTACAGAGACTAA
Protein Sequence: MKVHSQPMGVGGWYECLAADWLADMRSKQVPTSTTSARRLAALIRPLSGAAGAGGAAGAEGKPPEEEEERAGSPLGPGGPYACSHCRGSYPSRDQLERHETLHAPSTQVDNVKYSCKICPKSFDNVYRLQRHMISHIDCASIRKYKCNDCEKAFKFKHHLKEHLRIHSGEKPFECANCGKKFSHSGSYSSHMTSKKCLVMNLKMGRIKPNNPALNPDRNASRKRTNALVASQLNNNIASNNASFLPILPKYNEAAAAFFASMSPQENNFHRPPLGQPGMNPFYMPPGMPMSPASGIAPYTFPASLSQLFEQLASQQYQQRKMENPSPKQENLMGPNPEDLIEEVIEEDDKRSEGSAELVMDIEDDDNVSIKKEHEDRDTEQMLRSRDFENVPINNNGSEGDQSGFNTILKSVNASVTKHFFRANMESLSPVSAKVCPTVESPPVQHLTVKEEPEDPHRCLKCNLTFDGKSDLFEHEKLCGNMFRKHEGLAAQVAETVALNRLEAEMRASIQSGVSGSEDEDYGKDEHEDKASLHDSDRKIRVRTALSEEQQTVLKEHYAINPRPNREEFKKIAQQIGLDNRVVQVWFQNNRARVRRMTQVVAMSDQPLDLSTKKSSASVTSSPSPSPPCSISVTHSDSEEAVNLSQKSSRSTTPHRSHYLNTYPHSNCSSSSFIDFRLSPSPGEIISGQKRPMSQKMPVNPVMPMDKLLQYNDMTNGRSPILNMHMSSEKRHESSPPYDRPTWGDDLHLQNDYDDEASVLKKSKLKNSSDYKEGEGQFVCDQCDKTFVKQSSLARHKYEHSGQRPYKCAECDKAFKHKHHLTEHKRLHTGEKPYQCCKCLKKFSHSGSYSQHMNHRFAICKPYRD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00205017;
90% Identity: iTF_00953851;
80% Identity: iTF_00801686;