Hsem008805.1
Basic Information
- Insect
- Hipparchia semele
- Gene Symbol
- Zfx
- Assembly
- GCA_933228835.1
- Location
- CAKOGE010000047.1:2603502-2609326[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 0.015 0.8 10.6 0.6 2 21 248 267 248 268 0.95 2 18 0.0036 0.19 12.6 2.0 2 23 330 351 329 351 0.95 3 18 0.05 2.7 9.0 5.2 3 22 356 375 355 378 0.89 4 18 8.7e-07 4.6e-05 24.0 1.1 2 23 418 440 417 440 0.95 5 18 0.35 18 6.3 0.9 2 23 447 467 446 467 0.89 6 18 0.0042 0.22 12.4 0.9 1 23 473 495 473 495 0.98 7 18 0.0039 0.2 12.5 0.5 1 23 501 524 501 524 0.97 8 18 0.0085 0.45 11.4 1.4 1 23 533 556 533 556 0.95 9 18 0.03 1.6 9.7 5.6 1 23 566 588 566 588 0.98 10 18 0.00022 0.012 16.4 1.0 2 21 728 747 727 748 0.93 11 18 0.11 5.9 7.9 0.2 2 23 753 774 753 774 0.92 12 18 0.57 30 5.7 7.2 1 23 779 801 779 801 0.93 13 18 0.0037 0.2 12.5 2.2 2 23 807 828 807 828 0.95 14 18 0.079 4.2 8.4 2.7 1 20 831 850 831 852 0.93 15 18 2.7e-05 0.0014 19.2 1.7 1 23 867 890 867 890 0.95 16 18 0.00016 0.0085 16.8 4.0 1 23 896 918 896 918 0.97 17 18 5.4 2.9e+02 2.6 0.3 1 23 952 975 952 975 0.74 18 18 7.6e-05 0.004 17.9 1.2 1 23 982 1005 982 1005 0.96
Sequence Information
- Coding Sequence
- ATGAGGCAGGTGGACGTAAAGGCTTTAGTTTCGCATGTTATACGTGGAGACGGGGTCAACAAGTGCCGAATATGCATGGGAGATACTTCAGAGGGACAAGTGCATTTATCTGATACAGTTATAATGGAGGGAGATAAGCCCGTTACATTATCTGAACTGCTCGAAATCGTCACAGGAATTCAGGTACCACTGGAATGTGACCTGCCAGCCGGATTGTGCGTGGAATGCTCCACGTGTACCATAAATGCTGCTAACTTCAGATCAAACTGCAGAGAGACATTCACCAAATGGGACATGACATTACAACTTTTGTACAACCTACCCTCGCAGTGTTCTGAGCGGGACAAGATTTTATTTGCTGTATTGGATGACAACAAAATGACTTTCGTTATTGATATAAATGATTTAAATCTAGACACACCATCTGAGAGGCTACAGACACATTTGTCAACTCCGATGGATCTCAATTCAACAATTGATAGAAAAAAAGTGGAAACGGAAGAGTGTGATCTGAAAGAAACagtcaaaaatgtacaaaatacaaataaagaaGGGAGCGAAATTGAAGAAGTTGCCAAAAATGATGGACtagtcaaaaaaataattgaaatagaGGAACATAAAGTTAAAGATGTCAAAAGGAAAAGATGTAAATTAGACGATAGCGAACCCAAAGATgtcaaaaaaaatgaaagattaGTGGCAAAGAGAGTAAAAGGAGGAAAAACTGACCAAATACCGCAGTGTCCGAATTGCAATAAAAAGTTTGGTCACCCTCTTAAACTGTATTACCATTTGAGAGGTTCGAGGGATATGATACGAGCATGTTATGTATGCAGCAAAATTATGACACGTGACGAACTTGTATCTCACCTCGATGAAGTCCATAACGTGAATGTCTATGAATGTAAAAAGTGTCCTGCGCTATTACtgactaataaaaaatatatccagCATTTATCTAAGGCGCATTCGCGCGGCGCGTGCATTTGTGGAGACTGCGGGCATACGTTCCAATCTAACCAAGCGTTCTACGCACATATGACTGTACACAGAAGAAAAATCTGCCCAGGTTGCGGTAAAGTATTCCAAAACCAAACGTGCTACTTGCATCACAAAAAGAACTGCCCTCATTTTTTAGACAGAAATAGAAATTGCGAAACAGTAACAAAAATGACGGTAGAAGTGAAAAACgagaagaaaataaagaatattaaagcTCGTACACCTCCCAGTACTGGAGAGGTATGCATCTGTGACTATTGTGGTAAAACTTTTGCCAGGAAGAAGTATTTAACAGCGCATATACAAATAGTGCACATGAAAAATACTCACATACCTTGTAAGTACTGTGGGAAGTTTCTAGCGAACGCTCATATGACAGAACATTTAAAAAACCACGAGTTAGACTTGTCCTTTAAGTGCGAACACTGTGGTATCGTTCTTAAAAGTAGATTGGGTTACGTCCAACATTTAAGGTTGCATACGGGGGAACGGCCGTATGCATGCAAGATTTGTAAGGAGACTTTCAGTGCCGCGTCGAGACGCTCAGAGCATATGCGTAAAATCCACTCAGGAGCTGATGTAGTCCTCAAACACGCTTGTAAACTGTGCCCTGCCAAATTTGGACTGCCGTATAGGTTGAAGAAACACATGAAGTCTTCACATATAAACGAAGGCGATGAAACGTTACAGTTTGAATGTAACGAATGCCACGAAAAGTTTGGCTCATGCCGTGGGTTACTCCACCACAGCAGGATACATCAGAAAGTGGATTTCCCATATAAGAGACCTGAGAAAACTATCATGTTACAAGTGTTAAGTGATCCTAACTGTGTCTTAGCGGAGTCTGACCTGCCCGGAGGCATTTGCAGCGATTGCACGAACAGTGCAATATTTGCATGGAAGTTCAGATCGCTATGCAGCAGCTCTGACCAAGAATGGAGTCGAGTGACCACAGTTCTGACAAAAAACGCAGAAGATATCATCGTGAACCTCGATGACACAGTCTTCTACATATGCCTCAACAGAGAAGGTGCAATTTTCAAAGACAATGTGGACAAAAAACTTTCTTTAGAAGAAGCCGCGGACAGATTCAATTGTATCCTCAAGTCGGACAGAAGAACGGGACAAGAGAAGTCTAAAACACAAAACGTACAACAAAAAAATCTTCCCAAAACCAAATGTCGGATGTGTGGTAAATTGTTCAAACGTCCTCAACACTTGAACAATCATTTGGCTACAACTTCGATAGGCGTTTGCACGGTTTGCGGCAAGACTCTGCCCAAGGAAAAGTTGGCGAGACATTTGGAAAATCTTCACGGGAGATTTATACATCACTGCAAGATTTGCCACCATCTGTTCGACGACCAGTCTAGTTTGGATCGGCACAGCGAACTTCACGCGTACAACTTGCCACAATGCAGGATTTGCAAGCACGGTTTCAAAAGCGAGAGGTCCCTACGTGCCCATATGTTCGCGCACACTTTATTCAGCTGTGCGAATTGCAGTAAAACTTTTGAGAATCGAAAATGCCTCGCTTACCATAAAGAACGTTGCGCGGACACCAAAAAAACCGAAACCGAAGTTGAAGGGACCTATGAATGTCACGATTGCGGCCGAAAGTATACCAAGAAGCCGTCACTGAGGATCCATATAATACAGAAGCATTTGAATGTACTGCCGTTCGTGTGTCAGGTTTGCGGGAAGCGTTGTTCAACGAGAAACCATCTGAAGTCGCATGAGCTCGTTCACAAAATAGAACGGAAGATATACCAGTGCGAATGTGGTGCTAAAATGCGTACGGCCCTCGGATTCCACATGCACCAAAGAATTCATTCCGGAGAAAAGCCTTACGAGTGCGAGGAATGTGGGGACAGGTTCCTCTCAGCTTCGCGAAGGTTAGATCACGTTAAACGAAGGCACAGGGGTGGTGCCACTGCTCACAACTGTAAGCAATGTGGTGCAGGATTCATTAGGCCTTTCGAACTGAAAAAACATTATCAAACTGCACACTTTCAGCTGTACAATAAAGTGAAATAG
- Protein Sequence
- MRQVDVKALVSHVIRGDGVNKCRICMGDTSEGQVHLSDTVIMEGDKPVTLSELLEIVTGIQVPLECDLPAGLCVECSTCTINAANFRSNCRETFTKWDMTLQLLYNLPSQCSERDKILFAVLDDNKMTFVIDINDLNLDTPSERLQTHLSTPMDLNSTIDRKKVETEECDLKETVKNVQNTNKEGSEIEEVAKNDGLVKKIIEIEEHKVKDVKRKRCKLDDSEPKDVKKNERLVAKRVKGGKTDQIPQCPNCNKKFGHPLKLYYHLRGSRDMIRACYVCSKIMTRDELVSHLDEVHNVNVYECKKCPALLLTNKKYIQHLSKAHSRGACICGDCGHTFQSNQAFYAHMTVHRRKICPGCGKVFQNQTCYLHHKKNCPHFLDRNRNCETVTKMTVEVKNEKKIKNIKARTPPSTGEVCICDYCGKTFARKKYLTAHIQIVHMKNTHIPCKYCGKFLANAHMTEHLKNHELDLSFKCEHCGIVLKSRLGYVQHLRLHTGERPYACKICKETFSAASRRSEHMRKIHSGADVVLKHACKLCPAKFGLPYRLKKHMKSSHINEGDETLQFECNECHEKFGSCRGLLHHSRIHQKVDFPYKRPEKTIMLQVLSDPNCVLAESDLPGGICSDCTNSAIFAWKFRSLCSSSDQEWSRVTTVLTKNAEDIIVNLDDTVFYICLNREGAIFKDNVDKKLSLEEAADRFNCILKSDRRTGQEKSKTQNVQQKNLPKTKCRMCGKLFKRPQHLNNHLATTSIGVCTVCGKTLPKEKLARHLENLHGRFIHHCKICHHLFDDQSSLDRHSELHAYNLPQCRICKHGFKSERSLRAHMFAHTLFSCANCSKTFENRKCLAYHKERCADTKKTETEVEGTYECHDCGRKYTKKPSLRIHIIQKHLNVLPFVCQVCGKRCSTRNHLKSHELVHKIERKIYQCECGAKMRTALGFHMHQRIHSGEKPYECEECGDRFLSASRRLDHVKRRHRGGATAHNCKQCGAGFIRPFELKKHYQTAHFQLYNKVK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -