Hkul001189.1
Basic Information
- Insect
- Himalopsyche kuldschensis
- Gene Symbol
- NRG1
- Assembly
- GCA_028554975.1
- Location
- JAHFWI010000045.1:4722422-4729189[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.0004 0.03 15.4 1.5 2 20 200 218 199 221 0.91 2 13 3.3e-07 2.5e-05 25.1 1.2 2 23 226 247 225 247 0.96 3 13 0.5 38 5.6 2.7 1 23 252 276 252 276 0.93 4 13 0.16 12 7.2 4.6 2 23 283 305 282 305 0.95 5 13 0.009 0.67 11.1 1.9 2 23 313 335 312 335 0.97 6 13 0.00056 0.042 14.9 1.4 2 20 571 589 570 592 0.94 7 13 7.2e-06 0.00054 20.9 1.3 1 23 596 618 596 618 0.98 8 13 0.097 7.2 7.9 1.1 1 23 623 647 623 647 0.96 9 13 1.5 1.1e+02 4.1 3.2 1 23 654 677 654 677 0.93 10 13 7.8e-05 0.0058 17.6 3.3 1 23 686 709 686 709 0.98 11 13 8.1e-05 0.006 17.6 1.3 1 23 715 737 715 737 0.98 12 13 1.6e-07 1.2e-05 26.1 1.0 1 23 743 765 743 765 0.98 13 13 6.5e-06 0.00049 21.0 2.8 1 23 771 793 771 793 0.97
Sequence Information
- Coding Sequence
- ATGGCCATCAATTATCAACATAAATGTGTCATCAAGTTCGCGGAGTCTGATGAAATATATGTTTCCGATAAGGTTGATTTTTGTCAGACTTGTTTGACTGTCTCCAGAAGTGACGAACTTAAAGATATGATGAGGCTATATACGCATAATGGCAGCTATGAGATGTATTCCGAAATGCTGGATTGCTGCTATTCATTACAGATGGGAGATGATTCTAAAGAAGTATCAAAAAATATTTACATGATATGCAACTCTTGTATTGAAAAACTCCGCTTGGCGATCATCTTCAGGAATCGTATAGAAGAAGCTCAGGAAACTATCAAACAGATTCTCGGAAGCAGTGATTCAACACAGTCGAAAATCAATGATCTTGCAAGTTCTGATGATGACAATGAAAACTTCTCATCAGGAGATGAGAACTATGACCCATTACCTTTAGAACATGAGACCAAAAAAAGAAAGGGAATGGAAAGTAAAGAAAAAATGGTTGAACCAACAAAACTATCACGGATTGACAAAAGTCGTATAGTTAAAAAAAAGAAGAAAAAGAGAAGTTATGTTCTGAAGCTTCCATATCAAGTTGGCATCACTGATCTGAAATGCAAAATATGCCATGAAGAATTTGCTTCCAACAAGACACTCAAAATTCATATGCCGAAGCATTTTCCTTACCTCACATGTGAACACTGCGGGCGGGGCTTCTCGAATAGAAGTCAACTCAAGTCACACATGGCCGTTCACTCGACCAAAAGATTCGAATGTCCAAGCTGTCCGGGTAAAACGTTCAAAAGTAGTTCGGGTTTCAGATTTCACCACAAAATCAAGCATGAACGCAGTCTTTTTATCAAATGTCATCTATGCAGCGAGTGTTTCATGACCTACGACAGCAAACGCAACCATCTTATGAACGATCACGGAGTTAAATTCCCAAGGGTGAAGTGCAAATTCTGCGACGTGACTTTTGCGAGGCACAACAAGATTTCGGAGCACATCCGCAAAGTCCATCTCAAcgaacgcagtcacatatgcgatGCTTGTCTGGCAAACAGTAATGGCGAAAATATGAAAAATATGATGAGACCCTATTCTTACGGAGACAAACTGGAAATCTACTCGGAAATGATCAGCTATTGTTTTTCCGTGGAGATGACAGAGAATCTCAAAGAAAGATTGGAGGATGTATATCTCATTTGTGAATCCTGCATCAAAAGACTTCGAGAAGTAGCCAGTTTCAGGAAACAGGTTGAGGATGCTCAGAAGAATATAAAAAGACGACTCGCTAAAAGAGTCACGCCCCTCACTCTGGATTTGTCCAAGTACGATTTGAGCGCAGAGAATAGTGATGACCAATCGGGAGTTGAAGACAGTGATTTTGTTTCTTATTTGGTTGGCAAGTTATCAGCACCCCAGAAGCCATCGGCCATAAAAAAACAAAAGAAAACTGCTACGAAAATAGCCAAGAAACAGACTGTCAGGAAAAAAGTTCTGCCAAGGGGGCCAGTCCACAGATCTAATAGCCTGAAGGTCGTCAGAAAACAGTCTCAACCAGCAACCGTAGACCAGAGTCTTCCGAACAATGGGTCTGATCAAGCAAATATGCCCAAGAGAGTACCTGACGTAACTGAAACACACACCAAACCCAAAAAATCTCCATTTGTAAAAACCATGGGATGCAACGACTTGCCGTACGTCTTGGATAAATATCAACTGCATTGCAAAATATGTGATGAAACATTTGAAACTCACAAAAGTCTGCAGATCCACATGCCAGGACACTTTCCGAACTATACCTGTGAACACTGCGGTCGGGGTTTCGCCAATAATGTCCAGTTCAAGATACACAGAAATGTCCATTCCACGGAACGGTTTGAGTGTTCGCAGTGCCCTGGAAAATTCTTCAAGACCGCCGACTCCAGATTGGCGCACACCAAGAGAAAACATTCCGACAATCCCAACATTCACAAGTGTCCGTATtgccacgaccgttttgccagctacgacattcgacgcaaacatttaatcaccgtgcacgggaagatagaagaagtgcgcaagtacaaatgcaagctgtgcgagaagaccttcaccacgtcgggacaccgcgcgacgcacgtcaggaaaattcacctcaacgagcgcaatcacacgtgcaagacgtgcggtaaatccttcttcgcgaacccggccctcattcaacacatgctgaagcacacaggcgctagaaatttcccgtgcaacgtgtgcggcaagagcttccagaggaaatacaccctgacggagcacatgaagatacacaccggcgagaagaggcacgtctgcaacgtgtgcgggaaggcattcactcaaaagtgctctctgaaaggacacatgtcagtccacgagcgagaggGTCTCAAAGGGGAATCGTAA
- Protein Sequence
- MAINYQHKCVIKFAESDEIYVSDKVDFCQTCLTVSRSDELKDMMRLYTHNGSYEMYSEMLDCCYSLQMGDDSKEVSKNIYMICNSCIEKLRLAIIFRNRIEEAQETIKQILGSSDSTQSKINDLASSDDDNENFSSGDENYDPLPLEHETKKRKGMESKEKMVEPTKLSRIDKSRIVKKKKKKRSYVLKLPYQVGITDLKCKICHEEFASNKTLKIHMPKHFPYLTCEHCGRGFSNRSQLKSHMAVHSTKRFECPSCPGKTFKSSSGFRFHHKIKHERSLFIKCHLCSECFMTYDSKRNHLMNDHGVKFPRVKCKFCDVTFARHNKISEHIRKVHLNERSHICDACLANSNGENMKNMMRPYSYGDKLEIYSEMISYCFSVEMTENLKERLEDVYLICESCIKRLREVASFRKQVEDAQKNIKRRLAKRVTPLTLDLSKYDLSAENSDDQSGVEDSDFVSYLVGKLSAPQKPSAIKKQKKTATKIAKKQTVRKKVLPRGPVHRSNSLKVVRKQSQPATVDQSLPNNGSDQANMPKRVPDVTETHTKPKKSPFVKTMGCNDLPYVLDKYQLHCKICDETFETHKSLQIHMPGHFPNYTCEHCGRGFANNVQFKIHRNVHSTERFECSQCPGKFFKTADSRLAHTKRKHSDNPNIHKCPYCHDRFASYDIRRKHLITVHGKIEEVRKYKCKLCEKTFTTSGHRATHVRKIHLNERNHTCKTCGKSFFANPALIQHMLKHTGARNFPCNVCGKSFQRKYTLTEHMKIHTGEKRHVCNVCGKAFTQKCSLKGHMSVHEREGLKGES
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -