Basic Information

Insect: Heteropelma amictum
Gene Symbol: zfh1
Assembly: GCA_959613375.1
Location: OY390720.1:39207295-39212214[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.016 1.5 9.6 1.6 2 23 88 110 88 110 0.92

2 7 9.3e-06 0.00083 19.8 0.6 2 23 130 151 129 151 0.97

3 7 5.8e-06 0.00052 20.4 7.8 1 23 160 182 160 182 0.99

4 7 1.4e-05 0.0013 19.2 1.9 1 21 188 208 188 209 0.95

5 7 9e-05 0.008 16.7 4.2 1 23 705 727 705 727 0.94

6 7 2.2e-05 0.002 18.6 7.3 1 23 733 755 733 755 0.98

7 7 0.0015 0.14 12.8 4.3 1 21 761 781 761 782 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.016	1.5	9.6	1.6	2	23	88	110	88	110	0.92
2	7	9.3e-06	0.00083	19.8	0.6	2	23	130	151	129	151	0.97
3	7	5.8e-06	0.00052	20.4	7.8	1	23	160	182	160	182	0.99
4	7	1.4e-05	0.0013	19.2	1.9	1	21	188	208	188	209	0.95
5	7	9e-05	0.008	16.7	4.2	1	23	705	727	705	727	0.94
6	7	2.2e-05	0.002	18.6	7.3	1	23	733	755	733	755	0.98
7	7	0.0015	0.14	12.8	4.3	1	21	761	781	761	782	0.96

Sequence Information

Coding Sequence: ATGATGGCATATAATGACAGAAGGTGTATTCCAGGGTGCAGCGAGGACGAAGCCGGCGCTGAGGCTGCCAAAGTTGCCGACTGCGCGGGTGTGGCTGCGGCACGGCAAAGCGGCGGAGGGGGCAGCCGCCGTATAGGTGGAGGTGAAAACGTCGAAGGAGGCGCCGCTGTTGTCAGCAACGGTGGCGGTgtcggcggcggcggtggtggtggtggtagtGGCGGTGGTGGCGGCGAGGCGGGCTCGACAAAGCAGGGCGAGAGATGCCCACAGTGCGGCATGACATGTAGAAGTTTACACGTTCTCCAGCTTCATCTCGAAGACGTCCATAAAACTTCGTTCGCCAGCATCGACAAACACGATCTCGGCGCTCAATTCTCCCAAGTTTCTTGCAAAGTTTGCAACAAGACATTCGCGAACGTTTATCGTTTACAGAGGCACATGATCAGCCACGATGAGAGCGCAGTTTTGCGTAAATTCAAATGTCCGCACTGCGAGAAGGCCTTCAAATTCAAGCATCATCTCAAGGAACACCTCAGAATTCACAGCGGGGAAAAGCCCTTCCAGTGCAACAACTGCGGCAAACGTTTCTCGCACTCGGGCTCGTACTCGAGTCACATGACGTCCAAGAAGTGTCTCATAGTCAATCTGAAGAAGTCGCGGCAGAGCTCGATACCGCCGCAGAGCGTCGAGCGCGTGGCGAAAAAGTCCCAGCAGAATCATTCGTCGAATTCACGGCGGGAGGTGCCCGATCTTCTCGTCTCCAACAACAACACGTTCATGCCGATTTTGCCGAAATTGTCACCCTCGGATTATCGAGACATACAGCGGGACGGAGCAGGTATTTACGACATGCCGACGCTCCTGCCTCACATGATGGGCCTCGGCAGTTACTTTCTGCAATCGTCGATCGGAAAGATCCTCAATCAGCTGCACACGAAGCGACTGGACGAGGTCGCCGAACAGTTCGAGTCGCACCGCGAGGTCATGAGTCCCTCGACCGCCGACTCGGAGGGTACGGAAGGTACGGAGGGCAAGATTTCGCCATTGCCGACGGATCCGCAGGGTCTCGACGCTGTCAGACGAATTCTCGAAACGGTCAACACCTCCGTGACGAAACAGCTGCTCGAGGCGAACGTCAGAAAACTGGCTTCCTCCCCCGCCACCATAAAACGCGAGTACGACGAGGATTATCAGGATCAGGATAGCGAGATGTCGAGCGAAATGACTCACAGTCAAGAGTGGCAGCCCGGCGGGGATCAGTGCGACTCGCGGAGCGAGGGTCTCGCGGCTAAATTGGAGGAGGTTAACGCggcgccgccgccgctgccgccgcTGCTGCCGCCGTTGTCGTCCTCGGAACGCCCGAGTTTCAAGAGAAAAGCCGAGGACAACGTCGTCGAGATTTTCGAGGGCGATACGGAGGACGACGAGAGCGCACAGCCGCAGAACGAGTCGGGCAGGCGAGTCAGAGCTCGCTCGTTGATCGACGACGAACAATTGGCCGTTCTCAAGGGCTATTACGCGATAAATCCACGGCCCAAGAAGGAGGAAATCGCCATGATCGCGAATTACATTAATTTTCCGACGCGAGTGGTGCAAGTTTGGTTTCAAAATTCGCGAGCGAGGGATCGAAGAGAGTCGAAAATGCCGGGTCTCGTTCCACTGGCGAATctcggcggcggcggcggcggtcaTCTCAGCGTCGTCGAGCAACCCCTCGATCTGTCGAAGAAGGAGGCTTACGCGATATCGATGGTGAAGGACAGCAGCGACGGTGGCTCGAGCAGGCAGACGGCCTCCCCGTGCGGACCCACGAGAGAGGACGAGCGCGAGACGAGTCGCGTCTCGCGGTCTCGCGCCGACGTCGAGGACGTCGACGACTCGCCGCCGCTCGTTATCGACGAGGAGACGAGCGATTCCGGCCGCGTCAAGAAACCCGAGGTCGTCGTCAAGGAAGAGATCATACCCCCCAAGAGTCAACCGGTGGTCGTCCCGACAAAGACGAGCGAGCCCgtggctgctgctgctgctgctgctgctgctgctcctgCCGCCACGCGTGTGACGAGCGAACCACCCGCGGCTGTGGAAAACGAGCAAGAGGGCTTGTACTTTTGTGATCAGTGCGACAAAACATTCTCCAAGCACAGTTCACTCGCGAGACACAAGTACGAGCATTCCGGGCAAAGACCCTACAAGTGCGAAGAGTGTCCACGGGCTTTCAAGCACAAGCACCATCTGACGGAGCACAAGAGACTTCACACCGGGGAAAAACCCTTCCAATGTTCAAAGTGCCTGAAGCGATTCTCACACTCGGGTTCTTACAGCCAGCACATGAACCATCGTTACTCGTACTGCAAGCCGTACAGAGAATAG
Protein Sequence: MMAYNDRRCIPGCSEDEAGAEAAKVADCAGVAAARQSGGGGSRRIGGGENVEGGAAVVSNGGGVGGGGGGGGSGGGGGEAGSTKQGERCPQCGMTCRSLHVLQLHLEDVHKTSFASIDKHDLGAQFSQVSCKVCNKTFANVYRLQRHMISHDESAVLRKFKCPHCEKAFKFKHHLKEHLRIHSGEKPFQCNNCGKRFSHSGSYSSHMTSKKCLIVNLKKSRQSSIPPQSVERVAKKSQQNHSSNSRREVPDLLVSNNNTFMPILPKLSPSDYRDIQRDGAGIYDMPTLLPHMMGLGSYFLQSSIGKILNQLHTKRLDEVAEQFESHREVMSPSTADSEGTEGTEGKISPLPTDPQGLDAVRRILETVNTSVTKQLLEANVRKLASSPATIKREYDEDYQDQDSEMSSEMTHSQEWQPGGDQCDSRSEGLAAKLEEVNAAPPPLPPLLPPLSSSERPSFKRKAEDNVVEIFEGDTEDDESAQPQNESGRRVRARSLIDDEQLAVLKGYYAINPRPKKEEIAMIANYINFPTRVVQVWFQNSRARDRRESKMPGLVPLANLGGGGGGHLSVVEQPLDLSKKEAYAISMVKDSSDGGSSRQTASPCGPTREDERETSRVSRSRADVEDVDDSPPLVIDEETSDSGRVKKPEVVVKEEIIPPKSQPVVVPTKTSEPVAAAAAAAAAAPAATRVTSEPPAAVENEQEGLYFCDQCDKTFSKHSSLARHKYEHSGQRPYKCEECPRAFKHKHHLTEHKRLHTGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00266735;
90% Identity: iTF_00798475;
80% Identity: iTF_00798475;