Hami006779.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Heteropelma amictum
Gene Symbol
znf423
Assembly
GCA_959613375.1
Location
OY390722.1:21184530-21196335[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 8.6e-06 0.00076 19.9 1.5 1 23 97 119 97 119 0.98
2 20 0.21 19 6.1 4.9 1 23 125 147 125 147 0.98
3 20 1.1e-06 9.9e-05 22.7 4.1 1 23 153 175 153 175 0.99
4 20 0.00023 0.02 15.4 0.2 1 23 181 203 181 203 0.99
5 20 0.013 1.2 9.9 0.2 1 23 364 387 364 387 0.95
6 20 0.26 23 5.8 0.0 2 23 398 420 397 420 0.88
7 20 0.21 19 6.1 0.1 3 23 490 510 489 510 0.97
8 20 0.0039 0.34 11.5 0.2 3 23 526 546 525 546 0.96
9 20 0.00024 0.022 15.3 0.6 1 23 555 578 555 578 0.94
10 20 2.4 2.1e+02 2.8 0.1 1 23 583 606 583 606 0.91
11 20 0.7 63 4.4 2.2 2 23 679 700 679 700 0.96
12 20 0.00051 0.046 14.3 0.3 1 23 705 728 705 729 0.95
13 20 3.2 2.9e+02 2.3 0.1 2 23 798 821 797 821 0.82
14 20 4.6e-05 0.0041 17.6 1.0 2 23 837 859 836 859 0.96
15 20 1.1 98 3.8 0.6 1 12 868 879 868 891 0.76
16 20 2.8 2.5e+02 2.5 0.1 2 23 899 920 898 920 0.95
17 20 0.051 4.6 8.0 0.1 2 23 1107 1129 1107 1129 0.92
18 20 0.036 3.3 8.5 0.8 1 23 1139 1162 1139 1162 0.96
19 20 0.031 2.8 8.7 0.2 2 23 1205 1227 1204 1227 0.94
20 20 0.22 19 6.0 1.4 1 23 1234 1257 1234 1257 0.96

Sequence Information

Coding Sequence
ATGCTATTCAAAGGGAATAGTTCCCGATTGGAATTGCTAATCGGGAAAATCCAAGCACACAAGGAGTCGCCGTCGCCGCCTCGAGCTGACAAATGCAGTCCCAGGTCCAAAGATGCACTGGGCACCGGAAGTTCATCTTGGCACAGCGAGGATGCCGGCACAAACTCGCGGAGGGGTGGTGAAACTCCATCTTCTTGCGCTACACCGACTTCGGCGAGTTTTCCATCGGAACCGGAAGTCGACACCGAAGTTGGTGTCAATGTCGATGGCAATAATTCAGCAGCTCCTTATCCCTGTCAATTTTGCGACAGGACGTTTCCTCGACTTAGCTACTTGAAAAAACACGAGCAGAGCCATGGCGACCAAATGCCATATCGTTGCAGTTGGTGTTCGCGTTTGTTCAAGCACAAGCGTAGCAGAGATCGACACGTGAAGCTGCACACCGGCGACAGACGATATCGATGCTCTCATTGCGAGGCCGCCTTCTCCAGAAGcGATCATCTAAAGATTCACATGAAAACCCACGACAATCAAAAGCCCTATCAGTGCACGGCGTGCTCGCGCGGCTATAATACCGCAGCGGCTCTAACATCTCACATGCAGTCGCACAAGAAACATTCGAGTCCGAATCAAAATACGAAATTGGACTTTGATTGCGGACGTCGGAGTGTATCATCGCACAGTACGTCATCTCCGCCGATTCAAAATTCGCCATCACCGAGCTTGAATCTCGCATTGAGCGCGAAAAATTCGCTGAAATGTCAACAATCGATTTACAACAACAGCACATCGAAACCGCCTCTCCTGAATTCACCGTTGAAGCTCGCTTGCATGTACTGCACCAAGGACTCATTCACGAGTATGCAACAGTTGCAGATGCACGTACACGCGATGCATCAGGCGATATTAAACGGTGGAAGCTTAAAAATGGAAACGGCGGGTCTGATTAAACCGGAAACCAACAATTCAAAGCCCAGAGAACAGTTGCCGGTGGAGAGAAGCAGCAGCAATGATTACGAAAGAGCATTCCAGCCGGAGGaccgcgaaaaatcgttggaaaggGATAAAGTCAGCGGCGTTGAAAGTGTGTTTTCCTGCGGTCAATGCACGATGAAATTATCCAGCCTCAGCGAGCTTCGGGATCATCTGGTGATGATACATCGAAATGACAGTTTCGGTTCGACCCTGATGATGTGCCCTCTGTGCGGGATACCTTGTGCCTCTGCTGCCTCTTACGCCGAGCACTATGTCCTACAGCACTGCGAGAATCGTCGGGTACCAACGAAAGATTCGATAAATCGCGACTGGGACGGAACAAAGACGAACGGAAGTCGAGAAAATAGCAGAACAGGATCGGAAGATCGCGGTACGACGAGCAGATCCGATTTTGGGAATTCCGAGCCAGCTgacttgacgaaaaaacactCGAGACCCGGTGACACTGGCTACACAACTGGTACATTGCTCTGCGGCCAGTGCGGCGCAGCGTTGAAGgatttcgaatcgtttcgcgagcatTTGGCTCGTCATTTGCAGGCTGACCAGCAGAGCTGCGAGGTCTTACCGCGAAATCCGTGCCCAAAGTGCGGTACCAATTTTCCAGAGCGCGAAGACATGTTGACTCATCTGACCAAACACTACCTTGGCCAAGTAACGAAGGAATACACTTGTGGCGCTTGCAAAAAGTCCTACCCTCATCCGGATCTGCTGCAACGGCATCTGCTCGACAGTCACGCTCATCATCTTTATCGTTGCGCCGTTTGCCGGGACACCTTCGACTCAAGAGTCGCTATACAAGTTCACTTCGCAGTGAAACACAGTCAGGAGTGCCAGGTATATCGTTGCAACGCTTGCAGCGGATCCAGCAATGATAACTCCCCGGAGAATTCGCCGGGGGAAGgacgaaattattttcgaagcGAAGCGGAAATGGCGAATCACGTTAGGACGATTCACGCACCACCGAGcgtcattgagaaaagtcCTTTGCCGAGGAGCCCCGCTCCTCCACCGGTTACCAACGCAACCACCCCTAGATGCGTCTTTTGCGGGATTTGTTGCAACACGGATTTGGAACTGCAGCTTCATCTGGCGAGTCATTCGAGCAATTTGTATCGATGCCCGATTTGCAGGGAAGGATTTCCGGTTGAATTTCTGTTGGAGAGGCACATGGCTCAAACGCATCATGTCAACAATGACCGAAATGACGGCAGAGAAAATGGAAGAACGTACAGAGCATCGAGGTCCCAGGACGAAATGGCGAGATCACAAAAGCGTGGAAGATCTCCAGCCTCCAGCAACAACAACTCCTTGAATCAACGTGACAACAATAACAAACGAACGAACTACGGAGTGAGCAACGGCGCGGCGATATCATCGTCCAACGTCCAGCAGTGCGAGTTGTGCGAGAGAGGAGAGTTCGCAACGGAGGCGGAACTTCAGGCGCACAAAAAACTGGTCCATACACCGGTGAAACTGCAGAGCAAGTCGTTGCCGCTGTTGAGCATGACTTGCGCGTATTGCGGCGAGGTTTGTCGTTCTCGGAGCGACTTGGAGTCGCACACGAGGATTCAGCATGCCTCGAACGAACCCGGCGGACGTCACAAGTGCAACATTTGCGACGAGGTTTGTCCGTCCGGCGGAATACTGGCCGAGCACAAGCTTCAGACGCACTGTAAGATTCAGCTGAGCGACACTTGCGTAGTTTGTCGCGGAACTCTGGCGAACGAGGGGCAGTTCATCGAGCACGTTCAACGACACGGTATCGAAAGTGGCGAGACTCAACAAAGAGTCGACGGCGCTGTGCCCTCGTTGCCAGCCGCTTGCGTCGTTTGCAGGCAAACTCTCATGAGCGATTTGGAGTGCCGACTTCACGCGAGCCACCATTTAAGGGGTTCCTCGAACGTGACGCAAACTTCGGTTTCCAGTCCTGGACCAAATCAGAGCAAGGCCCAGCAGCCGCAAACGAGCTTCCAACAGGCGATTCTCAGCTGTTGCCTTTGTTTGCGCGAATTCAGTCCCGACGACTTTGTTAGTTTGCCGTCGAACCCCGCTGGCGCTGCCAATTCGTCGTTGAGGGTATGCAAACCGTGTTACGTTAGACACTCGCAAGGCTTGCCGATACTCAGTTCGCCTTACGAGCACGTGAGACGGACTAAAAGCGAAAGAAACCATTGGATCAATGGCAAAGATCGGACCAACAGGGAAACTTCGAGAGATCGATGGGACAGTGGGAACGACAGATGCCGCAGCGTTGACGAACGCGACAGAAACAACGGCGTTTCCGTTAAGGGGGTATTGAACGAACCTGATGAAAACAGATGCGACGAGTGCGgtgtgaaatttgaaaatctcgaCGAAGCGGAAATTCACAGAGTCAAGGAACATggaaagaatcgagaaaacgCGAATACTTATACGTGCATACAGTGCCAGATGTCGTTTTCGtccgaggaaaaaattcgtcaacaCGTGAGAAAAGTCCATTTGGAATCATCGAACAAAGCTTCGATAGAGGCTTTGCGCTGTCATCTTTGCATATTCGAAGCTAACAGCCCTCTTCAGCTCCAAGGACATCTGATTGAGCATACTTTCGCCGGGTGCGCTGGACTCTCTTGTTACATTTGCCAGGGACTCTTTACGACCCCTCTCGCTCTGCAGAATCACATGATGCAGCAGCATGGACTCGGTGCACGTCCTTACGACTGCAGCCAGTGCAGCCtcaaatttttcttccgtATCGAATTGGATCATCATGTGATAACGGTCCATCGTAGAAACGATTCTTCCTCACCGGCGTTGGACGTGGGACAAGAAGCAACAACGGAAAATCGAATTAATCCCACGACGATTAATCGAAATATGCCGGGAATTACCGATGACAATCACGCGGTTGAAGCTTGTTCGAAAATGATCACAGTCAAGGAAGAAATTGTCAATAGCCCTGGCGAGAAAGACATCAACGTTGACGATAATGCCGAAGAGAACGAAGACTCGGAATCGAGATACGAAGACTCGAGTGCGGTCGATACcaagatggaaaaatttccAATGACGCAGGAAGATGACGAGATTCAATCTTGA
Protein Sequence
MLFKGNSSRLELLIGKIQAHKESPSPPRADKCSPRSKDALGTGSSSWHSEDAGTNSRRGGETPSSCATPTSASFPSEPEVDTEVGVNVDGNNSAAPYPCQFCDRTFPRLSYLKKHEQSHGDQMPYRCSWCSRLFKHKRSRDRHVKLHTGDRRYRCSHCEAAFSRSDHLKIHMKTHDNQKPYQCTACSRGYNTAAALTSHMQSHKKHSSPNQNTKLDFDCGRRSVSSHSTSSPPIQNSPSPSLNLALSAKNSLKCQQSIYNNSTSKPPLLNSPLKLACMYCTKDSFTSMQQLQMHVHAMHQAILNGGSLKMETAGLIKPETNNSKPREQLPVERSSSNDYERAFQPEDREKSLERDKVSGVESVFSCGQCTMKLSSLSELRDHLVMIHRNDSFGSTLMMCPLCGIPCASAASYAEHYVLQHCENRRVPTKDSINRDWDGTKTNGSRENSRTGSEDRGTTSRSDFGNSEPADLTKKHSRPGDTGYTTGTLLCGQCGAALKDFESFREHLARHLQADQQSCEVLPRNPCPKCGTNFPEREDMLTHLTKHYLGQVTKEYTCGACKKSYPHPDLLQRHLLDSHAHHLYRCAVCRDTFDSRVAIQVHFAVKHSQECQVYRCNACSGSSNDNSPENSPGEGRNYFRSEAEMANHVRTIHAPPSVIEKSPLPRSPAPPPVTNATTPRCVFCGICCNTDLELQLHLASHSSNLYRCPICREGFPVEFLLERHMAQTHHVNNDRNDGRENGRTYRASRSQDEMARSQKRGRSPASSNNNSLNQRDNNNKRTNYGVSNGAAISSSNVQQCELCERGEFATEAELQAHKKLVHTPVKLQSKSLPLLSMTCAYCGEVCRSRSDLESHTRIQHASNEPGGRHKCNICDEVCPSGGILAEHKLQTHCKIQLSDTCVVCRGTLANEGQFIEHVQRHGIESGETQQRVDGAVPSLPAACVVCRQTLMSDLECRLHASHHLRGSSNVTQTSVSSPGPNQSKAQQPQTSFQQAILSCCLCLREFSPDDFVSLPSNPAGAANSSLRVCKPCYVRHSQGLPILSSPYEHVRRTKSERNHWINGKDRTNRETSRDRWDSGNDRCRSVDERDRNNGVSVKGVLNEPDENRCDECGVKFENLDEAEIHRVKEHGKNRENANTYTCIQCQMSFSSEEKIRQHVRKVHLESSNKASIEALRCHLCIFEANSPLQLQGHLIEHTFAGCAGLSCYICQGLFTTPLALQNHMMQQHGLGARPYDCSQCSLKFFFRIELDHHVITVHRRNDSSSPALDVGQEATTENRINPTTINRNMPGITDDNHAVEACSKMITVKEEIVNSPGEKDINVDDNAEENEDSESRYEDSSAVDTKMEKFPMTQEDDEIQS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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