Hami001975.1
Basic Information
- Insect
- Heteropelma amictum
- Gene Symbol
- topi
- Assembly
- GCA_959613375.1
- Location
- OY390720.1:32585904-32588533[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 16 0.19 17 6.2 1.1 1 23 256 278 256 278 0.96 2 16 2 1.8e+02 3.0 2.1 2 23 285 307 284 307 0.80 3 16 0.0025 0.22 12.1 0.4 2 20 314 332 313 334 0.92 4 16 6.4e-06 0.00057 20.3 1.0 1 23 341 363 341 363 0.97 5 16 3.8e-06 0.00034 21.0 1.9 1 23 369 391 369 391 0.95 6 16 0.049 4.3 8.1 0.7 2 23 403 425 402 425 0.92 7 16 0.27 24 5.7 4.5 1 23 441 463 441 463 0.98 8 16 0.097 8.7 7.1 0.1 1 23 469 491 469 491 0.95 9 16 0.26 23 5.8 3.7 1 23 501 525 501 525 0.91 10 16 0.00027 0.024 15.2 0.2 1 21 540 560 540 561 0.94 11 16 0.0077 0.69 10.6 0.3 1 23 566 588 566 588 0.98 12 16 2.1e-06 0.00018 21.8 3.1 1 23 594 616 594 616 0.98 13 16 0.00018 0.016 15.7 0.6 1 23 622 645 622 645 0.97 14 16 0.1 9.2 7.1 1.9 1 23 651 673 651 673 0.89 15 16 3.3e-07 3e-05 24.3 2.2 1 23 679 701 679 701 0.99 16 16 6.3e-06 0.00057 20.3 4.9 1 23 707 730 707 730 0.96
Sequence Information
- Coding Sequence
- ATGACCAGTACAATCGGGGGTGATTCGATAAGTTCGACATTGAGCGATGAGGAAAACTGCCTGGACGACATCGAAGTGACTAGCATCATTTGGTCACCGGATGATCCATCGTCAACCGGTGATTTCAACGAGCGCGATGTCAAATTTGAATCCAACGGCGACGACGAAGCTCTCGGACTTTGTCGATTGTGCGCGGGTCGCGCCATCGATcctgtatatatttatgaCGAATTTGGAGAATCGATGAGGCTCGCCGAGAAAATTAACACGTGCCTCAGTGTGAagataaaaaaaacggatcCTCTGCCCAAGCAATTATGCCACGTCTGCGTCGAGAAAATAAACTGGTGTGACGCTTTTGACGAGCAGTGCATAAAATCCGAGGAGACGTTGGAAGCGATGCTGCGAGACGAGAGCGAGCGcctggaaaatttgaaaattccaaaGAAGGAATTCCCATGCGACGTGGAATCCTGTCCCCTGTGCGTCAAAGGTCAAATGCACACGGGACAATTCGACTGTTCAACGAGCGCGACGGATCTTTGCGACAGCGATATCGTTATGGAGAGCAGCGACGAGGAAAAAGCATTGAGCAGCGTCAGcaaaggaaaattcgaaactGACGCAACGATCAGTCAACTGGAATATCTCGGCAGTAACAGCCACCAGTATCTGAAATGCGGCGCTTGCATGAATCTTTATCACACGAAAGAGAGCCTCGACCTTCACAAATGTAAGCCGAACGTTCAAACAACATCGAGACCGTACAAGTGTCTCGTTTGCGAATTGACATTTCCATTCGAGGAACGTCTGAACTTCCACATGAAGTTTCACAACGGCGCCAAGCCTCTCTATTGCGAGATATGCAACATAACGTTCGTCAAAGAATTAAAGTCATTTCATCATTACAAACGTTATCACTGCGAGGATAAGAACGTCTCGTGCCTGCAATGCGGCAAATTATTCGCGAATCAGCAACAATTGCGTATACACGTGTGCCTCGACGGCAAAACACGACCGCACGTTTGCTCAATTTGCAACAAAGGTTTTTCCGACGGTTACACGCTGAAGCGCCACATCGTGACTCACTTGCCGGAAAAACCGTACAAATGTTCGCAATGCTCGAAGAGCTTCACGCAAAAGTCGCGACTGAACAAACACGTGGCTGCTCACGGTATCGTGATCGAGAATACGCAGATTGCATGGAAATGCGTAGAATGCGGCGAAACCTTTGAAACGTGCAACGAGGCCGATATCCACAATCGTAAGAGTCACATCGACAAGATAAGCCTGATAGAGGAGCTGACAACGTCGAAGATTTATCATTGCGAATTTTGCAACAGTTATTTCAATGACGTGGAGTGTTTGAGAGAACATCGCAACGTTCACGTTATCGAGAAGCCTTACACGTGCAACGTCTGCGTGACGGTTTACAAATCTTACGCCGAGGCTGTGCTGCACTGGAAGGAACACCCGCGAAGCTTTCGCGTGGCGACGGTTCATCCGTGCGACGTTTGCGGCAAGGATATGAAAGAGATGTCGCTGTTGTACAAGCACAGACGGAAGAGATGTCATATAACGCCGAGGAAATCCGAGCTCGACCACAACATCGTCAAGTACGTTTGCGAATTGTGCGGCAAATGTTTCGACAAACCCGAGGACATAAAAGCGCACGGTAGAGACCAATGCTCGAAATTTCCATGCGACATTTGCGGCAACCTTTTGCCGACCGCGAATTCTCTACACGCGCATAAGAGAAGACACAGCGGTTTGCGGCCTTACGTTTGCAACATTTGCGGCAAAAGCTACACCCAATCGAGTCACATGTGGACGCACAAGAGATTTCACATGGGTGTGAAGCCCTACGCGTGCCAATACTGCGATCAGAGATTTACCATAAAACCGGATCTCGCTGACCACACGCGGAAGAAACACACGAGGGAACGTCCGTTCAAGTGCGATGTTTGCCACAAAGCTTTTTTAACTGGCTCGGTTTTTTATCAGCACAGGCTCATTCACCGAGGCGACAGACGATACAAGTGTCATTACTGCGAGAAAGCTTTTACGAGGACCGAGGCGTTGAACAATCACATTAAAATACATACCGGTGAAAAACCGCACGCCTGCGATGTTTGCGGAAGATGCTTCAGGCAAAAGGGCGATATGAGGAAACACAGGAGAACTCAGCATAATATTCCTAAAGAAGAATTGCCGTGA
- Protein Sequence
- MTSTIGGDSISSTLSDEENCLDDIEVTSIIWSPDDPSSTGDFNERDVKFESNGDDEALGLCRLCAGRAIDPVYIYDEFGESMRLAEKINTCLSVKIKKTDPLPKQLCHVCVEKINWCDAFDEQCIKSEETLEAMLRDESERLENLKIPKKEFPCDVESCPLCVKGQMHTGQFDCSTSATDLCDSDIVMESSDEEKALSSVSKGKFETDATISQLEYLGSNSHQYLKCGACMNLYHTKESLDLHKCKPNVQTTSRPYKCLVCELTFPFEERLNFHMKFHNGAKPLYCEICNITFVKELKSFHHYKRYHCEDKNVSCLQCGKLFANQQQLRIHVCLDGKTRPHVCSICNKGFSDGYTLKRHIVTHLPEKPYKCSQCSKSFTQKSRLNKHVAAHGIVIENTQIAWKCVECGETFETCNEADIHNRKSHIDKISLIEELTTSKIYHCEFCNSYFNDVECLREHRNVHVIEKPYTCNVCVTVYKSYAEAVLHWKEHPRSFRVATVHPCDVCGKDMKEMSLLYKHRRKRCHITPRKSELDHNIVKYVCELCGKCFDKPEDIKAHGRDQCSKFPCDICGNLLPTANSLHAHKRRHSGLRPYVCNICGKSYTQSSHMWTHKRFHMGVKPYACQYCDQRFTIKPDLADHTRKKHTRERPFKCDVCHKAFLTGSVFYQHRLIHRGDRRYKCHYCEKAFTRTEALNNHIKIHTGEKPHACDVCGRCFRQKGDMRKHRRTQHNIPKEELP
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -