Basic Information

Insect: Heteropelma amictum
Gene Symbol: -
Assembly: GCA_959613375.1
Location: OY390725.1:6134889-6140038[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.4e-05 0.0022 18.5 0.7 1 23 146 168 146 168 0.95

2 15 0.0009 0.08 13.5 1.1 3 23 176 196 175 196 0.99

3 15 0.00013 0.011 16.2 0.1 1 23 325 347 325 347 0.98

4 15 0.24 21 5.9 0.1 1 23 353 376 353 376 0.96

5 15 8e-05 0.0071 16.8 1.8 1 23 405 427 405 427 0.98

6 15 4.2 3.7e+02 2.0 0.0 1 23 443 465 443 465 0.83

7 15 1.2 1e+02 3.7 0.3 2 23 472 494 472 494 0.94

8 15 0.0022 0.19 12.3 2.8 2 19 502 519 502 523 0.95

9 15 0.00019 0.017 15.7 3.5 3 23 531 551 529 551 0.97

10 15 0.013 1.2 9.8 0.1 3 23 558 578 557 578 0.97

11 15 7.8e-06 0.0007 20.0 0.4 1 23 587 609 587 609 0.98

12 15 0.0034 0.3 11.7 0.2 3 23 617 637 615 637 0.97

13 15 0.003 0.27 11.9 0.2 3 23 645 665 643 666 0.94

14 15 0.13 12 6.7 0.0 1 23 680 702 680 702 0.93

15 15 0.12 10 6.9 0.0 1 20 1104 1123 1104 1126 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.4e-05	0.0022	18.5	0.7	1	23	146	168	146	168	0.95
2	15	0.0009	0.08	13.5	1.1	3	23	176	196	175	196	0.99
3	15	0.00013	0.011	16.2	0.1	1	23	325	347	325	347	0.98
4	15	0.24	21	5.9	0.1	1	23	353	376	353	376	0.96
5	15	8e-05	0.0071	16.8	1.8	1	23	405	427	405	427	0.98
6	15	4.2	3.7e+02	2.0	0.0	1	23	443	465	443	465	0.83
7	15	1.2	1e+02	3.7	0.3	2	23	472	494	472	494	0.94
8	15	0.0022	0.19	12.3	2.8	2	19	502	519	502	523	0.95
9	15	0.00019	0.017	15.7	3.5	3	23	531	551	529	551	0.97
10	15	0.013	1.2	9.8	0.1	3	23	558	578	557	578	0.97
11	15	7.8e-06	0.0007	20.0	0.4	1	23	587	609	587	609	0.98
12	15	0.0034	0.3	11.7	0.2	3	23	617	637	615	637	0.97
13	15	0.003	0.27	11.9	0.2	3	23	645	665	643	666	0.94
14	15	0.13	12	6.7	0.0	1	23	680	702	680	702	0.93
15	15	0.12	10	6.9	0.0	1	20	1104	1123	1104	1126	0.93

Sequence Information

Coding Sequence: ATGGATGTGTCGGGAGATTTAACGTTACAATGGGTGGAGGAGGTGGGAAATGTAATACACGAGGAAGTAATATGCGGTTTGGAGGCAGAAATCCCAGCTACGGAGGAAGAGGTGATCGGGGCGTGCGAAGAAGTGTCTATGGAGGAAACGGTCCAATCAGCGGCGGAGCAAACGCCGTCGGGCGATTCGGAGCCTCTCATGGTGGCGCAGCCCAGCGACATGGAATCTATTTACATCGTACCTCAGGATCAGGGCCACGATTACCTCAATATACAAGTGACGGAGGAAGTTATCACGGACAATTGGGACAGAGCTGGTCCTGACGATGGGGTCGAGATACCGGAAACCAAAGTGTCTCACGACAACCTACTCGAGTACGACGATATGGAGATACCATTGCCGATAGATCAGGATTCATACACGAATACGAGGCCCTATCCGTGCGACTTTTGCAGTCGCAGGTTTCGTAAAAAGGCAAATTTGATGAATCACATGGTGGCGCATCAGACCGATCGTCCGCACGGTTGCAATTTGTGCGGTGCGCGTTACGTGAGAAAATGCGACTTGATGAATCATCTGAAGATTCACGCGTACGCACCGTCCCGCGATGGTTTGGAGGATGATATGAATGACGATGATTCGCTGGCGCaagaagaggaggaaacgACCAAGGGTCGAAGGAAAAAGGTACAATCGAGTGCGCCGCGCAAACGTAAAAACAACACTGCCGCTGCGAAACGGAACAATCAGCTCGATGATTCGAGTAAAATCATCGACATGACTAAAACATTAGTCAATAAATCGTACGATTACGTTGACGAGGATATGAGATTGTTGGAAGAGATGACGAGTAGGAGTACCAACGTGCGAGCTGGTAATTACGCTTCGAGCTCCAGATGGACCGAGCACGTTACGAGCATCGACGTGGCACCGCAACCTCCGCGCTGGCCGATCACCGACCCGACGAAACCTTACGTTTGCCAATATTGCGGCGTCGGTTTCGCTCGCGAAAAAGCACTGGCGTCGCATTCTCGCATACACGGCGGTGACAGCCCCTTCGAATGTACGAATTGCGGCGATATGTTCTGGGACGTGAACGCTTTGCGCGAACACGTTAGAATCAAACACGGCGGTCCGCCCGTGCAAGCTACCAATGATGAATTCGATCCGAATGACAATACAACGTATACGGGTGACGAGAGATTTGGCGAGTTTTACTGTGATACCTGCGGTGTGCCGTTTCATCGTTTGGATCTTCTCAAACGTCATCGAAAAATACACGTTAAACAAGAGGTAACCGATGTCGTGGATGGACCAATACAGCATCACGCTTGCAACGTTTGTGGCGAATGGTTCGAGGGAGCACTCGCTCTATTGGCGCACGCTGAATTACACGCGAGGTCACCAACACGTCGGTGTTTATTGTGCGGTGAGCAATGCCGCGACGATGCCGAGGTGGCCGAACACGTTAGGCAGAATCACGCTGAGGACGCGCCACCGAATACCTGCACAATGTGTGGCAAAACTTGCAAGGACAAGCGCAGTCTCCTAAAGCATTCGTGGGTACACAACACTGACAAGACCTTCGGTTGCACCAAGTGCGGCAAGCGTTTTCACAGCAAAGCTAGACTACGCAGACACATGGTATCGCATCGCAACAAAATGGTAGCTTGCGACGAATGCGGCGAAGAATTTCCCGACGGCAGGGCTCTGGTGAGCCATCGTCATTCGCACAACAAGGATCTCGGTGGGAGATCATTTCCGTGTCGCGAATGCGGCAAAACTTTCGGCAGTCGAAGCTCGCAACAGATTCACATACGTATACACACGGGCGAGCGTCCGTACGGTTGCAGATTCTGTTGGAAGGCTTTTGCCGACGGTGGCACATTGAGAAAGCACGAGCGCATACACACCGGAGAAAAGCCCTACGGTTGCGCGATATGTCCCCGAGCTTTCAACCAGCGGGTCGTTCTCCGCGAGCACGTGAGAGCTCATCACTCGGGCCCCGACCCAAAATGTCACGGTAGCATGACGCCGTATCTCTGCAAAGTCTGCGGCGATTCTTACGCGACATCGGAGGAGATCGTCGCTCACATAGTGCAGCACTGCGACGACAATACGGCACTGCGGCGCCAACCGCAGATAGGACCGAGAAAGTACAAGAGGAGACGCAAGCTCAAGCAGCACGACCCGCCGACGCTGTCGCTGCCCGTACGCCCGACGGTAAACGAGAATTTCAACGTTCTCGATGCCGCCTCGGACTCGGACGACAACACGAAGCGAAAACTCGGCCGTAAGAACAAGCAGCGCTCCAGCGTCGAGGACGGGTATCAGAACGTGCTGAAGAGCTTCGAGTCATCGTTGCAGAATATCAATTCGATCGTGAGTAACACTAAATTAAAACCTTCGAAATCGAAGATCGCGAAAAAGCATGGTAAAAACAAAGGTAACGCGAGCGAGGACAAAAAGTCGGAGACGCAAACTTCGGGACAGCCGGGACGTCCGAAGATGATACACACGCAAAAAACCCGGGTGCCCGTTGACACCGCAACGGACGGTGTGAAAAAAGGTCAAAAAACGAAGACCCTCGTGACGCGAACACCGAAGGTGATGCCGAGCGAGCACAAAGCCGGCGTGTTCCCGGGCGGCGAGAGAAATCGCCCGAGAACGAAGAACGTGAGTTATCACGTCGAGGGTAAATTACAAATAACACCGGCGACATTCCCGAAGCAGAAGGAGGAGGACACGACGGTGTTCGCGGCGTCAAACGCGTTGAACGATGAAAGAACGACGATGGGAACGACGAGAGCCTCGCAAATGGCGAGCAAACGCGCCGCGGCGAACAATCACGCGGCGAGCACAAACAACAATGGCAATTTGTTGggaatcgacgataaaaccGAGAGGGCCGCAACGCCGAAGAAACGAATCGTAGCTAAGAGAGTGAAAAAGCAGCAGAAGGAAGTCGCGATAAAGCAGGAACCGATCGATCAACCGGATGAGAGCGATATGGAAATTCGCGACAATAACAATTCCGGTGACATCATCAACTCGAGTGCTTTCAGTAACGAACAGATGACCGATCCTCACGCTCATTTCGAACCGAGAATTTTGAATGCCCGCGAAGAATCGATATTGCCCGATCTCGATGATGACATCAGTCACAGACGCGACGTCGTTAATTCcggtaaaatgaaaataagcCTCAAGGTCGAAGCCACCGCGCCGAGAGTGCTCATGGAACCACGCGGCGTCACCATCACTCCGGCTGAGGATATTCCCGAAACTATAATTCCCGATGCTCTCGAGTACACGTGCGAAATGTGCGCCGCGGTTTTTGGCAGTCGGGCGGAATTACTCATACACGTACCTATACACATTTGA
Protein Sequence: MDVSGDLTLQWVEEVGNVIHEEVICGLEAEIPATEEEVIGACEEVSMEETVQSAAEQTPSGDSEPLMVAQPSDMESIYIVPQDQGHDYLNIQVTEEVITDNWDRAGPDDGVEIPETKVSHDNLLEYDDMEIPLPIDQDSYTNTRPYPCDFCSRRFRKKANLMNHMVAHQTDRPHGCNLCGARYVRKCDLMNHLKIHAYAPSRDGLEDDMNDDDSLAQEEEETTKGRRKKVQSSAPRKRKNNTAAAKRNNQLDDSSKIIDMTKTLVNKSYDYVDEDMRLLEEMTSRSTNVRAGNYASSSRWTEHVTSIDVAPQPPRWPITDPTKPYVCQYCGVGFAREKALASHSRIHGGDSPFECTNCGDMFWDVNALREHVRIKHGGPPVQATNDEFDPNDNTTYTGDERFGEFYCDTCGVPFHRLDLLKRHRKIHVKQEVTDVVDGPIQHHACNVCGEWFEGALALLAHAELHARSPTRRCLLCGEQCRDDAEVAEHVRQNHAEDAPPNTCTMCGKTCKDKRSLLKHSWVHNTDKTFGCTKCGKRFHSKARLRRHMVSHRNKMVACDECGEEFPDGRALVSHRHSHNKDLGGRSFPCRECGKTFGSRSSQQIHIRIHTGERPYGCRFCWKAFADGGTLRKHERIHTGEKPYGCAICPRAFNQRVVLREHVRAHHSGPDPKCHGSMTPYLCKVCGDSYATSEEIVAHIVQHCDDNTALRRQPQIGPRKYKRRRKLKQHDPPTLSLPVRPTVNENFNVLDAASDSDDNTKRKLGRKNKQRSSVEDGYQNVLKSFESSLQNINSIVSNTKLKPSKSKIAKKHGKNKGNASEDKKSETQTSGQPGRPKMIHTQKTRVPVDTATDGVKKGQKTKTLVTRTPKVMPSEHKAGVFPGGERNRPRTKNVSYHVEGKLQITPATFPKQKEEDTTVFAASNALNDERTTMGTTRASQMASKRAAANNHAASTNNNGNLLGIDDKTERAATPKKRIVAKRVKKQQKEVAIKQEPIDQPDESDMEIRDNNNSGDIINSSAFSNEQMTDPHAHFEPRILNAREESILPDLDDDISHRRDVVNSGKMKISLKVEATAPRVLMEPRGVTITPAEDIPETIIPDALEYTCEMCAAVFGSRAELLIHVPIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01057843;
90% Identity: -
80% Identity: -