Basic Information

Insect: Heteromyza rotundicornis
Gene Symbol: Znf518a_1
Assembly: GCA_951394025.1
Location: OX596011.1:82595633-82601107[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.008 0.65 11.1 0.7 1 23 136 158 136 158 0.98

2 16 1.9 1.5e+02 3.7 2.1 1 23 164 187 164 187 0.93

3 16 4.9e-06 0.00039 21.3 1.0 2 23 467 488 466 488 0.97

4 16 9.7 7.8e+02 1.4 6.8 1 23 494 517 494 518 0.93

5 16 0.27 22 6.3 0.7 1 23 542 565 542 565 0.93

6 16 2.9 2.3e+02 3.1 5.5 3 23 615 635 613 635 0.95

7 16 0.075 6.1 8.1 5.9 5 23 758 776 755 776 0.92

8 16 0.015 1.2 10.3 0.8 1 23 782 805 782 805 0.96

9 16 0.85 68 4.8 0.1 2 23 842 864 841 864 0.94

10 16 0.067 5.4 8.3 1.3 1 23 878 901 878 901 0.96

11 16 0.26 21 6.4 1.2 1 23 964 986 964 986 0.95

12 16 0.0047 0.38 11.9 4.2 1 23 997 1019 997 1019 0.98

13 16 1.1e-05 0.00091 20.1 0.2 1 23 1024 1046 1024 1046 0.97

14 16 0.0005 0.04 14.9 3.4 1 23 1052 1075 1052 1075 0.94

15 16 0.00015 0.012 16.6 0.0 2 19 1081 1100 1081 1101 0.94

16 16 0.00047 0.038 15.0 3.2 1 23 1110 1133 1110 1133 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.008	0.65	11.1	0.7	1	23	136	158	136	158	0.98
2	16	1.9	1.5e+02	3.7	2.1	1	23	164	187	164	187	0.93
3	16	4.9e-06	0.00039	21.3	1.0	2	23	467	488	466	488	0.97
4	16	9.7	7.8e+02	1.4	6.8	1	23	494	517	494	518	0.93
5	16	0.27	22	6.3	0.7	1	23	542	565	542	565	0.93
6	16	2.9	2.3e+02	3.1	5.5	3	23	615	635	613	635	0.95
7	16	0.075	6.1	8.1	5.9	5	23	758	776	755	776	0.92
8	16	0.015	1.2	10.3	0.8	1	23	782	805	782	805	0.96
9	16	0.85	68	4.8	0.1	2	23	842	864	841	864	0.94
10	16	0.067	5.4	8.3	1.3	1	23	878	901	878	901	0.96
11	16	0.26	21	6.4	1.2	1	23	964	986	964	986	0.95
12	16	0.0047	0.38	11.9	4.2	1	23	997	1019	997	1019	0.98
13	16	1.1e-05	0.00091	20.1	0.2	1	23	1024	1046	1024	1046	0.97
14	16	0.0005	0.04	14.9	3.4	1	23	1052	1075	1052	1075	0.94
15	16	0.00015	0.012	16.6	0.0	2	19	1081	1100	1081	1101	0.94
16	16	0.00047	0.038	15.0	3.2	1	23	1110	1133	1110	1133	0.94

Sequence Information

Coding Sequence: ATGGATTTCAGGCTTGTTTGCCGGACTTGTCTGGCATCGGATGATGCAGAATTCTACAGGCTGGATGCGCCAATAGTGTGCGATGAGGACGAGGAGAAGGTCAGTTTCATGGAGTGCCTACGCTTCTGCACGCGCCTGGACGATGTAGCACAGTTGCCCGTCTACATTTGCACCGAATGTAGCCGGGCGCTGCAAGTAGCTTACAATTTCATACGAAATGCGGTCGAGGCGCACGAAATTTTGCGCCAGAAATTGTGCGTCGCCCCATTGCAGCAGCAGCGCAGCAATGGCCAGCATGTGGGTGTTATAAAGAGAGATATCGGCGCGGACAGAGCAAGgAATTTTACCAGCAGTAGCAGTGCTGCCATTGTCACCGCCGCCAGTGCTGGAGAAAGGGTAATGCGTTTCCGTTGTAAGATATGCGCTGTGAAATTGGATACGAAAAAATCGTTGAAAGAACACGTCAAAGTGCATTTGGATATAATCTCATACTGCTGTCAAATATGCGATTTCGAAAGTAAAAAGCGCAACCCTTTAATCGAGCATTACAGCAATTCTCATGGCGTGGTGCCGACACGCAACCAATTAAAACCGAAAACCCTAACACATTCACAAGCAAATAATGTCAACTATGGCGACATGGAAGACACAAAAGAGGACATCCAATTGGATGACACAAAGGAGTACATCAAATTGGATGAGGTTTATTCGCAAATGGAGCAAATACACAATCCGCCAGCGTCCATAAAACAGGAACAAGAAGAGCAGGAAAAACAGTTGGAGTTGGAGCGAATTAAATTAGAACTCCAACAGCAAGAACAACTCGAACAATGGCATCctcaacaacagcaaccattTCATGATGAacgccaacaacaactacatcaacagcaacaccaacaatTTCACAATGAACAGCAACTGCATCATCATCAACCGTCACTGGAAGACGAACAACAACTACTGCAGCAACATATTGACAATGTGCTGTCAACGGAGACGAATAATATGCCTGAGCTAGCAGCGGATATGAACGATTTTGGCAATGACTTCAACATGGCCAATGAAATGAGTGTCGGCAATGAGTTTATCGTCATGGCCGATGGCACTGTGGAAGAAGTTATGGGCAATGGTGTGGTCATTGAGTATATAAATGCAGTAGAGGATGGCACTACCCTGGAGAATGGCCTAGTCTTGAATAATATGGTTCAAATGGAGGCGAATGCATCGAATGTGGACGAGTTGGTTACCATGGATGTGGATGATATTATAATTGAAGAAAGTGTCGCCACAGAAGTTGCAGATGAATATAGCCAGAATATCCTGCCACCAGCACCATTACTACCGCCAGCACCATCACTACCGCCACGACAACAAGCGGCAAATTCGAAGaaaatcaaatgcaaaatCTGCTCTGCCGTTTTCAACACAcaagaaaaactcaaaaagcaCATGTTAACCCATAATGaaaTTCCGCATTTCTTCTGTGACAAGTGTAAATTTTACACATTCTTCAAGATCGACTTGACACAACACTACAAAACCAAACACCACCTGCAGCCCACGTACAAGCAATTGCTTCCGAAAAACAAAGTTGAGTCCACTGAGGAGAGCGGGTACATCTATTCCTGCGACATGTGCCTGTTCGAGTCGAATCTCAAGGGGAATTTGCGTCGTCATTATTTGGCCAAACATCAGACGGTGGCAACGGACGTACAGCTAAGGCCCGCCAATGCAGATGAATTCGACGATCTCAGTGCAATGCCGCCGGCACCTCGAGTTGTTGTCAAACAGACGAATAACGTGAAATACGTCAAGCCTGATTTTCCCGACGGCATGCATTGCAAGAAATGCAATGAAGTTTTCTACTGGCGCAATAAGCTGAAAGAACACTACCAGCACCACACGCTCGAAGAGAATGCCCAGCTGCGTCTGCAGCCGGCCGAAGTCAGTCAGTACAACGGCGTTGACGCGGAAATCGAGAGCTCTCCCAGTGCCAGCGCCAGCGCCGGCGTTTATACTATACCCTCCGATGCCATACCACAGGTGGTGGAAATGGATACTTCCATCGATAATGACAtcgatttcgatttcaatGGTGACGCCCTGTTCGAAGACTTCGACGAAGATGAAATCGATGACCAAGATGACCAAAATGAATTCCAAGATTTAATTCTAACCAGCGATGATGATTTCGAAGACATAATCCAAGAGCAGAATCTCGATGACGAACAATCACAATCCGCCAGCGTGCTGCCTTCTCATTGCATTCACTGTAATAAGAAGTTCTTCAGCCaatatcaatttgaaaatcacATGTTCATACATAGAGGACTGGCGCCTTATCGCTGCGAGATGTGTACGAATTTATACAATACCAAACGTGCCCTGATTCGACACTACAAGGCGGTTCATAAAAAGATGCCCACCCGCGATATGATACAGGCGAAGGGCGATAAAGTTTCTGTTGATCGTATGCCAGTGGAACACTTAAATCTCGAAAAGCAAAAGTCAATTACCTTGATGTGTGCGAAATGCCCTTTTGAGTCGACGGAgatacaaaatttacaaatacatttggcCACGAGTCATGGCATAAACGATGaaaacttcattttacaaaAACTACCTTTTGAGTGCCCGCGTTGCATACGTTCTTACGCCAGCAAAGTGCGTCTGATTCGTCACTTAGAACGTTGTCACTCTGTGGCCACGATAatccagcagcaacaacagccaccGCCAGTTAACGGCTCCCTACCAACATCCGCAGCTGGCTCAAGATGTGGCCTAGTAGAGCTAATTGAATCTAGAACCGAAGTGGAAGACGTTGACGCATTGATGATGTCGGCGGcggcgtcgtcgtcgtcaacACTGGCAGCCGACTACTATCTATGCAATATATGCCAGTTCGTATGCGATTCGATGCAATCTCTGAACGAGCACAATCAAGTGCATACCGGCAATAAGACGCGTGACCAATTTCCATTCCAATGCGACATTTGCAATTGCAAGTACAGGTCGGTTGAGGCCTTGCGTCATCATGCGAAGCGACATGTGGCGCGTAAATTCAGTTGCGCCGAGTGCCCGAAATCGTACATAAATCGCACCGAACTGGAGAAGCACATGCTGTTGCACTCGGGTGACTTGCCCTATAAATGCGATTTATGCGAAAAACAATTCGGCTATCCCCATCATTTGAAACGTCACAAGGATATCGTACATTTCGGCAAGCGGGAAACGTGCCCTGTGGAAGGTTGCGGGAAAACATTCACCACACAAGGCCAGCTGAAGATACACGCTTGGGATCATAACGGAAATATACCATACAGATGCAGCTACTGCGGacacaatttcaaaaagcGCGAAGCATTACGCCAACATGCCTTTAAAATACACAAGGTTACACTTACCGAGGAGGAAATTGCCGAGATTTTCCGAAAGATGACCGGTTATACCAATCCGCATGATTTCACCATTGCCGTTTCGGATGGAAAAATGTTACGTCGTTCTGACATGGAAGCATCACGAGCCATTGAGATTTCCGAGCAGTCGGATGATAAGAAAAATGTTCTAGTAGAGTACTTGTAA
Protein Sequence: MDFRLVCRTCLASDDAEFYRLDAPIVCDEDEEKVSFMECLRFCTRLDDVAQLPVYICTECSRALQVAYNFIRNAVEAHEILRQKLCVAPLQQQRSNGQHVGVIKRDIGADRARNFTSSSSAAIVTAASAGERVMRFRCKICAVKLDTKKSLKEHVKVHLDIISYCCQICDFESKKRNPLIEHYSNSHGVVPTRNQLKPKTLTHSQANNVNYGDMEDTKEDIQLDDTKEYIKLDEVYSQMEQIHNPPASIKQEQEEQEKQLELERIKLELQQQEQLEQWHPQQQQPFHDERQQQLHQQQHQQFHNEQQLHHHQPSLEDEQQLLQQHIDNVLSTETNNMPELAADMNDFGNDFNMANEMSVGNEFIVMADGTVEEVMGNGVVIEYINAVEDGTTLENGLVLNNMVQMEANASNVDELVTMDVDDIIIEESVATEVADEYSQNILPPAPLLPPAPSLPPRQQAANSKKIKCKICSAVFNTQEKLKKHMLTHNEIPHFFCDKCKFYTFFKIDLTQHYKTKHHLQPTYKQLLPKNKVESTEESGYIYSCDMCLFESNLKGNLRRHYLAKHQTVATDVQLRPANADEFDDLSAMPPAPRVVVKQTNNVKYVKPDFPDGMHCKKCNEVFYWRNKLKEHYQHHTLEENAQLRLQPAEVSQYNGVDAEIESSPSASASAGVYTIPSDAIPQVVEMDTSIDNDIDFDFNGDALFEDFDEDEIDDQDDQNEFQDLILTSDDDFEDIIQEQNLDDEQSQSASVLPSHCIHCNKKFFSQYQFENHMFIHRGLAPYRCEMCTNLYNTKRALIRHYKAVHKKMPTRDMIQAKGDKVSVDRMPVEHLNLEKQKSITLMCAKCPFESTEIQNLQIHLATSHGINDENFILQKLPFECPRCIRSYASKVRLIRHLERCHSVATIIQQQQQPPPVNGSLPTSAAGSRCGLVELIESRTEVEDVDALMMSAAASSSSTLAADYYLCNICQFVCDSMQSLNEHNQVHTGNKTRDQFPFQCDICNCKYRSVEALRHHAKRHVARKFSCAECPKSYINRTELEKHMLLHSGDLPYKCDLCEKQFGYPHHLKRHKDIVHFGKRETCPVEGCGKTFTTQGQLKIHAWDHNGNIPYRCSYCGHNFKKREALRQHAFKIHKVTLTEEEIAEIFRKMTGYTNPHDFTIAVSDGKMLRRSDMEASRAIEISEQSDDKKNVLVEYL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -