Basic Information

Insect: Heteromyza rotundicornis
Gene Symbol: topi_2
Assembly: GCA_951394025.1
Location: OX596010.1:69665234-69666950[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0048 0.39 11.8 1.0 1 23 254 276 254 276 0.98

2 9 1.1e-05 0.00091 20.1 1.3 1 23 282 306 282 306 0.97

3 9 7.5e-05 0.0061 17.5 3.0 1 23 313 338 313 338 0.98

4 9 0.0014 0.11 13.5 0.4 1 23 347 369 347 369 0.95

5 9 1.3e-05 0.0011 19.9 0.9 1 23 377 401 377 401 0.95

6 9 0.00049 0.039 15.0 0.9 1 23 407 429 407 429 0.97

7 9 0.012 0.95 10.6 1.4 2 23 436 458 435 458 0.96

8 9 0.013 1.1 10.4 1.2 1 23 464 486 464 486 0.97

9 9 9.6e-07 7.7e-05 23.5 0.5 2 23 493 514 493 514 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0048	0.39	11.8	1.0	1	23	254	276	254	276	0.98
2	9	1.1e-05	0.00091	20.1	1.3	1	23	282	306	282	306	0.97
3	9	7.5e-05	0.0061	17.5	3.0	1	23	313	338	313	338	0.98
4	9	0.0014	0.11	13.5	0.4	1	23	347	369	347	369	0.95
5	9	1.3e-05	0.0011	19.9	0.9	1	23	377	401	377	401	0.95
6	9	0.00049	0.039	15.0	0.9	1	23	407	429	407	429	0.97
7	9	0.012	0.95	10.6	1.4	2	23	436	458	435	458	0.96
8	9	0.013	1.1	10.4	1.2	1	23	464	486	464	486	0.97
9	9	9.6e-07	7.7e-05	23.5	0.5	2	23	493	514	493	514	0.97

Sequence Information

Coding Sequence: atggaaattcacAAGAGTAGCGATTCTAATGCTTTGTGCCGGTGTTGCCTTCACCTTTTGGATCCAACGAAGCAATTCCCTGATGTATTCCTCATAACGGATTTGGCGAAAAAACTGGCGCTGGTCACATCCCTAACCGTGGAAGCACAGGATCGATTCCCCAAGCATTTGTGCGACAGTTGCTTTAACAATGTGAACGATTTCCACCAGTTTCAAGCCATGTGTGTGGAGTCCGTGCAGCGATTTGATGAAATGTGTAAATCTAAAGTTTCTGTGGCTTCGGCGGTATTCGAGGATGAGGAACAGCTGGAGTTCGATTTGAATGGtcaaatgaaaatagaaataaccGTAACCGAACCGGatataattttcgaaaatctgTCCAGGGAATCGGCGGAGGAATCGGAAGATGAACCACTAATGAAGCCAACGAAGAGTAATCGGCATCCGAAGAAGGCGATTAAAACGATTTCAGACAAACGTAGAACCAGAAGCTCTACATTAAAACAGAAGGCTGATGATTACGTAGAAAGCGACGAAGTACCGGAATACTCAGATGATAGAGCGTCCAGTGATGAAGGAGACTGTGATGATAATAGAAGGGAAGAGCAGCAACAGCCCGTGGATAGCGAGGATGAATTCTTGATACCAAAGAGGAAAAGGGACAAATCCAGTTCGAATGATGTCTGCAACAAACGCAAATACCACAAACGAAATAGCGAGCCATCACCAGGCGACGCCAAGTCCAAGCCTTCAGTGTTCCAATGTGACGTCTGTCCCACGCGCTTCTTTGTCGAGCACCGTTTGATAGCGCACAAGCGCGGCCATGAAGGCCTAGTCCCCTATCCCTGTCCCCGCGATGGCTGTGACAAATCCTTCAATCGCTGGTATTGTCTCAGCGAGCACCTGAAGCAGCACGAGGGCACGAATCGGTGGTACAAATGCGAAGAGAACGGCTGTGGCAAGGTCTACAAACACAAGCCCACGCTGGCCATGCACCTGCGCAAGTGCCACAAGCGTGGTCCCGAACTGAAGTCTCACATTTGTGAGATTTGTGGCAAGGTATTCAAGGCATCGGCCATACTCAACGACCATCGCTACACGCACAAAGATAAATCAGAGCTCCCATATGCCTGCGAACAGCCGCAATGCCAGCGACGCTTCTCAAATAAGGAGAAACTGAAAGTGCACATGATGCGGCATGCGGGCATCAAGAACTTTGTCTGTCCCTACTGCGGCATGCGCAAGACAACGCGCAACGAGCTGCGAACTCACATCAACTACCACACACTGGAACGGCGCTGGCCGTGTCGCTTCTGTGCACACGTCTGCAATAGTGCGGGCAATTTGAAGATGCATGTGCGTACGGTCCACGAGCGGGCCCGGGACTATGCATGTCGGTTTTGCGAGCGTACATTCGCCAAGCCGGACACACGCAAATACCACGAAATGACCCACACGGGCGAGAAGCCCAACGAGTGCAAAGAGTGCGGCAAGCGATTTACGCAGCCGGCAGCATTGCGCACACACAAGAAGATTCACCAACGTCTGACGAGTATAATGTACGTGACGGAGGGCGTCGTGACGAACTCTGGGGACGGTGGGCCTGTTGATCAGGCCGAAATACCAAACAGCGACATAAAGTCcttattgtaa
Protein Sequence: MEIHKSSDSNALCRCCLHLLDPTKQFPDVFLITDLAKKLALVTSLTVEAQDRFPKHLCDSCFNNVNDFHQFQAMCVESVQRFDEMCKSKVSVASAVFEDEEQLEFDLNGQMKIEITVTEPDIIFENLSRESAEESEDEPLMKPTKSNRHPKKAIKTISDKRRTRSSTLKQKADDYVESDEVPEYSDDRASSDEGDCDDNRREEQQQPVDSEDEFLIPKRKRDKSSSNDVCNKRKYHKRNSEPSPGDAKSKPSVFQCDVCPTRFFVEHRLIAHKRGHEGLVPYPCPRDGCDKSFNRWYCLSEHLKQHEGTNRWYKCEENGCGKVYKHKPTLAMHLRKCHKRGPELKSHICEICGKVFKASAILNDHRYTHKDKSELPYACEQPQCQRRFSNKEKLKVHMMRHAGIKNFVCPYCGMRKTTRNELRTHINYHTLERRWPCRFCAHVCNSAGNLKMHVRTVHERARDYACRFCERTFAKPDTRKYHEMTHTGEKPNECKECGKRFTQPAALRTHKKIHQRLTSIMYVTEGVVTNSGDGGPVDQAEIPNSDIKSLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -