Hrot006549.1
Basic Information
- Insect
- Heteromyza rotundicornis
- Gene Symbol
- -
- Assembly
- GCA_951394025.1
- Location
- OX596010.1:87285089-87286776[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 5.6e-05 0.0045 17.9 0.6 1 23 89 111 89 111 0.96 2 11 3.8e-07 3.1e-05 24.8 1.1 1 23 117 140 117 140 0.98 3 11 1.9e-05 0.0015 19.4 0.8 1 23 146 168 146 168 0.98 4 11 0.001 0.082 14.0 1.8 1 23 174 196 174 197 0.95 5 11 1.4e-06 0.00012 22.9 0.2 1 23 204 226 204 226 0.97 6 11 0.32 26 6.1 1.1 1 23 232 255 232 255 0.93 7 11 0.022 1.8 9.7 0.1 1 23 261 282 261 282 0.96 8 11 0.00034 0.027 15.5 2.3 1 23 288 310 288 310 0.97 9 11 2e-05 0.0016 19.3 1.6 1 23 316 338 316 338 0.99 10 11 0.015 1.2 10.3 1.2 1 23 344 369 344 369 0.88 11 11 0.00064 0.051 14.6 0.1 1 20 375 394 375 396 0.94
Sequence Information
- Coding Sequence
- atggtgcGCAGCAGACGCTCTATTTCGAAAGAAGATGCCTCCTCGGTGCTGGCCGACAGTGGCATTTCGCTTTCATCGCCACCGGCCGCCCTCCACGAAGAGGACGAAGAACAGCTTTTACTCGATTCGCTTTGCACCACCGACGACGAGGACAACGATGATGATTACGTGGTCCCAGCAGCAACAAAGCCGAAAGTTGAACCATGCAAAGTGGAACCCTTGGCGCCACCGGCTGCCCCGTCCGCCAAGAAACAACGCAAAAGTCACATTTGTGATATTTGCCAGAAGGAATTCGGCGGCAATACCGATCTCAAGCGTCACCAGCTCATCCACTCCGATGAGCGTCCCTTCAAGTGTGAGCAGTGCGACAAGTCCTATCGCCAGGCGGTGAACTTGAAGAATCACATTACCACCAGTCATGAGCAGCAGAAGCTGTTCTCGTGCGAACAGTGCCCGAAAACGTTTGCGCTGAAAGAGCGTTTGCGCTTGCATATGCGTTTGCATTCGGGTGAGAAGCCCTATGCGTGCAGCTTGTGTGAGAAGAGATTTGCACGCGGTGGCCAGCTCCACCAACATGTGGTCACCCATCACAAGGGCACCTCCAAACAGTTCATATGCGAGAAGTGCTCCACGGGCTTTTCCACCCCGGCCAATTTGCGCGCCCACATGGAACGCCACGAGCAGGGACCCGATCACTTTTGCGAAATTTGCAACGAACATTTCCTCAGCGACGTTGTGCTGCGCGCTCACATCAATAAGGCCCACTACAAGTTGAAGCAATTCGACTGTGAGATTTGCCAGAAGACCATCGAAGACGATGACTTGGCCACGCACATGAAGACGCACACGAATGTCAAGACTCACATTTGCGAGGTGTGCAATTCGTATTTTATGCAGAAGTCCCAGTACAACGTGCACATGCGTATGCATACGGGCGAGAGGCCCTATCAGTGTCGGATTTGCTGGCTCACCTTTGCCCACTCGAGTGTGCTGAAACTGCACATACGCAAACACACGGGCGAGAAACCCTTCAATTGTCTGCTCTGCAAGGACGAAGTGGCCTTCTCGCAGTTGGCCCACCTCAAGACACACATGAAGAAAatccacaaacaaaataatccCTACATGTGCGAGGGCTGCAATCAATTCTTCAAGGTCAAAGTGGAGCTGCAGGCTCACACGGACAAGTGCGACGCGTGCGACACCAGCATCGAACAGCAAAACGCCAAGAACAGTGACGAGCAAACCCTGTCGCATTTGCGTTTCCTCATTGCGGTGCTGCTGAAGAAGATCTCGCCCGAACAGAAACTGCAGCAGCTGGGCTATGAGAAGCGTCTGATTGATAATGTGGTAATAGCCTCGTTGAAGTTGGCCAATCGCAAGGCTTTCGATGATCCCAAGTTGCCTGCCATCGAGCGAATGCGTTTGAATGTCGAGGAATTCCTGAACTGGATTGTGCCCGCAAAGGTAATGGAGAAGTTCCGCCAAGAGGAGCTGACGGTTGAGTGTATTTTGGATAAAATCGTCACCATGTACATGAAGCAGAAGTAA
- Protein Sequence
- MVRSRRSISKEDASSVLADSGISLSSPPAALHEEDEEQLLLDSLCTTDDEDNDDDYVVPAATKPKVEPCKVEPLAPPAAPSAKKQRKSHICDICQKEFGGNTDLKRHQLIHSDERPFKCEQCDKSYRQAVNLKNHITTSHEQQKLFSCEQCPKTFALKERLRLHMRLHSGEKPYACSLCEKRFARGGQLHQHVVTHHKGTSKQFICEKCSTGFSTPANLRAHMERHEQGPDHFCEICNEHFLSDVVLRAHINKAHYKLKQFDCEICQKTIEDDDLATHMKTHTNVKTHICEVCNSYFMQKSQYNVHMRMHTGERPYQCRICWLTFAHSSVLKLHIRKHTGEKPFNCLLCKDEVAFSQLAHLKTHMKKIHKQNNPYMCEGCNQFFKVKVELQAHTDKCDACDTSIEQQNAKNSDEQTLSHLRFLIAVLLKKISPEQKLQQLGYEKRLIDNVVIASLKLANRKAFDDPKLPAIERMRLNVEEFLNWIVPAKVMEKFRQEELTVECILDKIVTMYMKQK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -