Basic Information

Insect: Heteromyza rotundicornis
Gene Symbol: -
Assembly: GCA_951394025.1
Location: OX596010.1:15924540-15927506[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.0055 0.44 11.7 0.4 1 23 115 138 115 138 0.92

2 16 0.064 5.2 8.3 2.1 3 23 145 166 144 166 0.93

3 16 3.7e-06 0.0003 21.6 4.6 2 23 176 198 175 198 0.97

4 16 0.0098 0.79 10.9 0.3 2 23 295 317 294 317 0.95

5 16 0.00031 0.025 15.6 1.1 2 23 331 353 330 353 0.91

6 16 3.4e-05 0.0028 18.6 2.6 2 23 363 385 362 385 0.97

7 16 0.00013 0.01 16.8 6.8 2 23 544 565 544 565 0.98

8 16 4.8e-07 3.8e-05 24.4 2.8 1 23 573 596 573 596 0.94

9 16 2.3e-05 0.0018 19.2 0.3 1 23 601 624 601 624 0.94

10 16 0.00015 0.012 16.6 6.9 1 23 634 656 634 656 0.96

11 16 0.18 14 6.9 4.0 1 23 661 683 661 683 0.97

12 16 3e-07 2.4e-05 25.1 0.4 1 23 689 711 689 711 0.96

13 16 1.8e-05 0.0015 19.4 0.7 1 23 717 739 717 739 0.98

14 16 4.6e-07 3.7e-05 24.5 1.5 2 23 746 767 745 767 0.97

15 16 2e-07 1.6e-05 25.6 1.8 1 23 773 795 773 795 0.99

16 16 0.041 3.3 8.9 0.1 1 23 800 823 800 823 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.0055	0.44	11.7	0.4	1	23	115	138	115	138	0.92
2	16	0.064	5.2	8.3	2.1	3	23	145	166	144	166	0.93
3	16	3.7e-06	0.0003	21.6	4.6	2	23	176	198	175	198	0.97
4	16	0.0098	0.79	10.9	0.3	2	23	295	317	294	317	0.95
5	16	0.00031	0.025	15.6	1.1	2	23	331	353	330	353	0.91
6	16	3.4e-05	0.0028	18.6	2.6	2	23	363	385	362	385	0.97
7	16	0.00013	0.01	16.8	6.8	2	23	544	565	544	565	0.98
8	16	4.8e-07	3.8e-05	24.4	2.8	1	23	573	596	573	596	0.94
9	16	2.3e-05	0.0018	19.2	0.3	1	23	601	624	601	624	0.94
10	16	0.00015	0.012	16.6	6.9	1	23	634	656	634	656	0.96
11	16	0.18	14	6.9	4.0	1	23	661	683	661	683	0.97
12	16	3e-07	2.4e-05	25.1	0.4	1	23	689	711	689	711	0.96
13	16	1.8e-05	0.0015	19.4	0.7	1	23	717	739	717	739	0.98
14	16	4.6e-07	3.7e-05	24.5	1.5	2	23	746	767	745	767	0.97
15	16	2e-07	1.6e-05	25.6	1.8	1	23	773	795	773	795	0.99
16	16	0.041	3.3	8.9	0.1	1	23	800	823	800	823	0.91

Sequence Information

Coding Sequence: ATGGATTCCATTAGAAAGCTGGACGCTGAACGCATTTGTCGTGTTTGTCTGCAAGAAAAAACGGATTTGTATCTGATATTTGACGAAGCTTTTGCAGAGGGCGGTACACCTATTTCGGTCATACTAACCGAGTGCACCCGATACAGAGTGGAGCGTCATGATGAACTGCCACATCAGATGTGCGGCGATTGCATGGAATCGGCACGCAGTGCCTATCGCTTCAAGCGACTGACCGAGCAATCCTATTTGACCCTATTGACAGTACTGGATGTGAAAGTTAGGCCCAACCACAAAACGAACGAATGGGCGGACATCTCAACACAAACTGACCAACTGGCCATCCATCCGTGCGAAATATGCGGCAAACAATTCTTTAGCGAAGTCGATGTGCGAGAGCATCGATTCATAGAACACCGAGGCGCCGACAAAAATTGTCGGTTATGTGGCGAGTCATTCCAACACATACGCAAGCTAAGATCACATCTATCACTGATGCATCCGGACGAAGGCACAGTGCACGACATAAAGTGTCCGCTCTGTCATAAGCAATTCTCACGTAAGGATCATATGAAGCGGCATTTGCGGGTCATACACAAGCAAAGCACTAAATCTGTAAGTACCAAAACTGAGTTGGTTACTGTTGATGTTGACATGAAACCGAATGCAAGCACTAAAACTGAGCCGGTTGAGGTTGACATGAAACAGGATGAAAGTACGAAAACTGATTTGGTCCATGTTGACTTGAAAGTGGATAATGACGTCGATCATGATTGGGGTAGTATCAAAGATGACTTGCCAGATGAAGATGATAGTATGTTGGGAGACACTAAACCACAGGAACCGCAAGCGGGCTCCTCTAAAACTCTTGTTCGAAAGTATTTAAGCTGTTCACTGTGTTCCGACAAATTCGTACAGAAGGTTGATTTACTAAACCATATACGCAACATACACAAGAAGAGCCCAGAAAGTCGGCTCCCTGCCGATCCTAAAAAGTGTCAAGTTTGTGGGGAAACCTTTAAATTGCGGCGCCTGTTGAAGCGCCACTTGGCGTTTGAGCATCCCAACGAAGGCCTAACAAATGATATGAAATGTCTGATATGTCAGCGTCAATTTTCGCGTAATGAACATATGAAACGTCACATGGCCACCGTTCATGGCGAGAACTACGAATGCTCAAAAGTCTCACTCGAGGAACCGGAAATCGATTTTATGTCGGATATTGCCCAACGGGAAGTGGCTAATACGATAAGCACCAATATGTTGCAATGGCATGGTCTTGACAACGTTACCCCAGACATTTGCGATGACGCCGAGATGGATGCAATCGATCCCTTTTCTAGTGGTGACGAGCAAAAAGTAAAGACGGCCAATAAACCGCAAGTAAATATAAAAGttgaACCCACCGATGGATTCAAGTCGGATTCAAGTGATAATTCCTTTGCAAATGACTTGGAACTGGAATGTGACGCTAATGCAATAAAGAAACTAAAGGAAAGTAGTTGCGAAAGTGACGACGACAACAAGCCTATCGCAGATTTGTCGCCCAAGCCCAAAGTGAAAATTATACGCGAATATCTGGAAAAGAAGGTGCCAGCCAGGCGACGAGTTGGCATtaaaaatgcagaaaatcgCTGTACGGAATGCCAACGCACATTTTCTCGCCACAGCCATATGCTGCGGCACATGCTGTCGCATGTAGCAGACGCCGAAAAGCCACACGCCTGCCCCAATTGCGGCAAGAGATTTACGCGAAGCGATCATCTCAAGACGCACATAATGAACGTGCACCAGACCAAGGAATTCAAATGTGACCAGTGTAAGTTGGCATTTGCTAGAAACGAAGAATTGACGCGCCACATAGAAGCTCGACATGGACAAGAGCCGAATGCCCACAAAATACACGACTGTGAGTTTTGCCACAAAAAGTTCACCAGCAAAACCTACTTGCGCAAGCATATACTAATGCACACGGATCGAATTTTTGCGTGTAAATTCTGCGATCAGACATACAAGGATCGCACTGCTTGCAAGGATCACGAGAAGACGCACAGCGTAGAGCGTAAGTTCTTGTGTTCGGTGTGCGGAGAGAGTTTCGCGCGCAACGATTATCTACGGGTGCACATGCGCAGACACACCGGCGAGAAGCCGTACAAGTGCCAGTACTGCGGCAAGGGATTTCCACGCGCCACCGATGTTAAAATGCATGAACGTTACCACACCGGCACGAAGCCGAAAGTCTGTCAGCTGTGTGGAAAAGCATTCCATCGCGCCTACAACCTCACCATTCACATGCGCACTCACACCGGCGAACGTCCGTTTAAGTGCGACCAATGTCCGAAGAGCTTTACACAGAGTAACGATCTCAAAGCCCATACAAGACGGCACACAGGTGAGCGTTTCAAGTGCAGTGAATGCGATGCCGCATTCCTGCAGTTGTATGGCTTGCGTCAACATGCCCTGGGAGTTCACGGCATCCAGATCGAATCTACCACTGGCCGATTACAAAAGTTTCCACCTATATTGGTCGTTGAGCATCCTTTAGAGCTGCATTTGCAACATTCTTTACAACAACCGCCGGCAGATGCACTGCCGCAGCATTTGCAACAATCTTTACAATCACCGCCGGCAGATACACTGCCACCACGCATATACACCGACTAA
Protein Sequence: MDSIRKLDAERICRVCLQEKTDLYLIFDEAFAEGGTPISVILTECTRYRVERHDELPHQMCGDCMESARSAYRFKRLTEQSYLTLLTVLDVKVRPNHKTNEWADISTQTDQLAIHPCEICGKQFFSEVDVREHRFIEHRGADKNCRLCGESFQHIRKLRSHLSLMHPDEGTVHDIKCPLCHKQFSRKDHMKRHLRVIHKQSTKSVSTKTELVTVDVDMKPNASTKTEPVEVDMKQDESTKTDLVHVDLKVDNDVDHDWGSIKDDLPDEDDSMLGDTKPQEPQAGSSKTLVRKYLSCSLCSDKFVQKVDLLNHIRNIHKKSPESRLPADPKKCQVCGETFKLRRLLKRHLAFEHPNEGLTNDMKCLICQRQFSRNEHMKRHMATVHGENYECSKVSLEEPEIDFMSDIAQREVANTISTNMLQWHGLDNVTPDICDDAEMDAIDPFSSGDEQKVKTANKPQVNIKVEPTDGFKSDSSDNSFANDLELECDANAIKKLKESSCESDDDNKPIADLSPKPKVKIIREYLEKKVPARRRVGIKNAENRCTECQRTFSRHSHMLRHMLSHVADAEKPHACPNCGKRFTRSDHLKTHIMNVHQTKEFKCDQCKLAFARNEELTRHIEARHGQEPNAHKIHDCEFCHKKFTSKTYLRKHILMHTDRIFACKFCDQTYKDRTACKDHEKTHSVERKFLCSVCGESFARNDYLRVHMRRHTGEKPYKCQYCGKGFPRATDVKMHERYHTGTKPKVCQLCGKAFHRAYNLTIHMRTHTGERPFKCDQCPKSFTQSNDLKAHTRRHTGERFKCSECDAAFLQLYGLRQHALGVHGIQIESTTGRLQKFPPILVVEHPLELHLQHSLQQPPADALPQHLQQSLQSPPADTLPPRIYTD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -