Htit077524.1
Basic Information
- Insect
- Hetaerina titia
- Gene Symbol
- ttk
- Assembly
- GCA_037158775.1
- Location
- CM073774.1:53168211-53187130[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 2.9e-06 0.0024 20.8 3.2 1 23 683 705 683 705 0.98 2 10 6.7e-07 0.00056 22.9 1.4 1 23 711 733 711 733 0.98 3 10 2.9e-07 0.00024 24.0 1.3 1 23 739 761 739 761 0.97 4 10 6.7e-06 0.0056 19.7 2.5 1 23 767 789 767 789 0.98 5 10 3.5e-06 0.0029 20.6 1.4 2 23 798 819 797 819 0.96 6 10 4.9e-05 0.041 17.0 1.3 1 23 825 847 825 847 0.98 7 10 2e-06 0.0016 21.4 1.7 1 23 853 875 853 875 0.98 8 10 7.7e-06 0.0065 19.5 0.1 1 23 881 903 881 903 0.98 9 10 2.7e-05 0.022 17.8 7.9 1 23 909 931 909 931 0.96 10 10 0.00013 0.11 15.7 0.6 1 21 937 957 937 958 0.93
Sequence Information
- Coding Sequence
- ATGAGAAGTTTGCCATGGGTACGGAAATATTTGAGAGACGAGAAGTGGGGTATCACAGGAAGGCTCTTCGCCCAGGGCGCCAAGTTCCCTCGAAAGCCCTGCTACTCCCCGAGGAAGTCAAATATCTCAGCGCCCACTTCGGCAAATCAGGTCCTCTCGCAGGTGCTCCATCATTTTTTTGCTGTCTTTTTCAACAACACGCTCGGCCCCCCTGGAGGATTATTGAGATCGTCATTCGTGCCGGTAATAGGCTCCCGCTATCGCCTTTCCCGCACCCTATTCCTCCAACTGCTGGTGGAAATTGGCCCTCCAGTTAGTTCCCTTCGGATAGAGGACACATGCGGGCTCACGGGACGGAAGACTGGCCGTGATTCGGTCCGTGTCTGCTCACAGACCGGAGGAGAGATGGAAAACCATCTGCACGTGCAATGGAAGCACCACCAGGAGGGAGTCCTCAAATTCCTTGAGGAACTCCAAGCCACGGAAACGTTTGTGGACGTGACACTGTGCTGTGAAGGACAAAGACTCAAAGCCCACCGCGTGGTCCTATCGGCATGCAGTCCGTACTTACAGCAAGTCCTCGTCGACAACCCTGGGGAGCACGCAACCATAATCCTCCATGACATCGGAGCCGAAGAGATGCGATCGCTCCTGAGGTTTATGTACTCCGGGTCGGCGAGTTTACCCCGGCGGTGCCTCCGAGCTTTCCTGCGGGCCGCACACGCCCTGCAAATCAGCGTCCTGATGCCGGGTTTTGAACACGCACTCACGGAAGAGATCCCTCGCCATCACCAAGGCCGCCAGGGACCAGAGGAAGGTGCCACCGACAGCGTCCCACCGCCTCCCCTGAGCACGCGCCCTTCCGCCCCCGAAGTCATGCTCCCCCACGACCTTTCCACCTCGTCGTCCTCCGGTGCCAAAACCGAGTTGCACTACGGCTCGAGCCACGAGGACGGCTCGAAGCGAAGGCGTCATTTCGCCAGCGGGATGACTGCGAGGTCCCCAGAAGTCCACCCGGCGTCCGTTTACCGGAGCGAGGACTCCTGGGGCAACGCCTTCCGGGAGGGCCTCATGGACCACTCCTCCATTCCACCGAGGCCCACCCTGGTCCCCCCGAGGCCCACACCCGTCATGAAGTCACCCTGGAGCCAGAGGCTCGGCTCAGCTGCGCCTCCCTGGAGGACGTCCTCGGTCATTGCGCCAGTTCGCCCTCCGACGCCTCCGCCGTTGCCCCCTCGAGTCGAGCCGATGGACCTGTTGACCGTTCCAGGGATGACGCCTGACACAAGGAAGCCCTACTGCTGTCCATCGCCATTTTGCCCATCCCCATCCTCTACCTCATCTGCATACTCCTCTGCATGTTCCTGGGCGCCCCAGTCTCCCTCAGCTCTCCCGACATCGCGCCCTCCCTCCTTACTCTCTGTCCCCAACAAGATCCACACGGCAGAATCCCCAGCAGAAGGAACGGCCGCTTTGGCCATCGCGACTGCGGACCTGCGGACCCTTTCGCCGAACCCAGGCCCCGTCCCCAACCCCACGAACCCCTCCACACCCACAACGCAGCCATCTCCGCCACCTTCGCCATCTCGCTTCACCCTGAAACAACGCCGCCTCAGAGACTTCTACCGGTCTCTCCAATCGACGGGTAACACATCCGCAGATGACTCCCAAAGCAGTGACAAACAGCTTGGTAATCCTTCAATGGAAACTAAGGACGAAGACTCCCTCCCTGTGCCGGCGTCTCCCCTCGAACCGACCTCTCCATCGAGACCCCAGTGGCCCAGCGAATCTCCAGTCGCCGTGGAGCAGTCCGTAATCAGGCTCTCCAAGAAATCGGCCTTCCAGCCCCCGTTGATCGTCGTCTCTCCGCCACAGTCAACACCGGAGACTTCAACAAGTGGAACATTCAACACCCGGGACGAAGACAAGCGGCCGCCTTTGCCCACCTTAATGCCCACTCTGGTGGTTCATCCCCCCGCTTCGCCTAACGGAGCGAGTCCCCAGGGGTCACCGGCTGCCAAGTCCCCCTCCAGCAGCAGCGGACCGCACACGTGTGAGACGTGCGGGAAGACGTTTGGGCGCCGACAGTTACTGGAGCAGCATCGACGCACCCATACCGGAGAGAAACCATTCGAGTGCTCCGTGTGCGGGAAGAGTTTCACGCAGCGAGGCCATTGGAGCGTGCACCAGAGGCTGCACGACGGCTCCCGGCCGCACATCTGTCCTGTGTGTGGGAAAGCCTTCGTGTCGCGTGCTTCTCTCAAGGTCCATCACCGCACCCACACGGGCGAAAAACCCTTTCGCTGCGAAGACTGTGGCAAGCAGTTCAGCCAGCTCCGAAACTTCAAGTACCATCGCTCCGTCCATGAAGGCACGAGGGAGTTCGCCTGCACCTGCCCCGAGTGCGGCAAGCAGTTCAACGACCGAGGGTACCTGAGCTCCCACCTCAAAATCCACCGCAACCGGAAGGAGTACGCGTGCGAACACTGCGAGAAACGCTTCAACCAGCGCGTGGCCTACAACATGCACGTCCGCATCCACACGGGCGAGAAGCCACACGAGTGCGAGGAGTGCGGTAAGAGGTTCGGACGGAAGATGCTACTGCGGCAGCACGCCCGTACCCACACAGGGGAGCGGCCGTTCCGCTGCGCCGTCTGTGGCAAGGCGTTCGCGGACAGGAGCAACATGGCCCTTCACGCCCGGCTACACAGCGGGGAGAAACCGCACTCGTGCGACCTCTGCGGGAAGGCGTTCACCAAGAAGCACCACCTCAAGACACACATGAACTTCCACACGGGCGTCAAGCCGTACGCGTGTCAGAGGTGCGGACTCCGGTTCAGTCAGTCCAGCAACATGAGGACCCACGCAAAGAAGTGCACGGCGGAAGCGGGGTCGGCTGCTGCCGGCTCGGCGACGGGAACCCCGGAGACCCCGTCGGACAGCCAGGGGAGTCTAACCCCTGGCCTCGCGACGAATCCAGAGCAACAGATGATGCTGTCGCCCGGCGAGCCGAAAATCGGCCCGGCTGAAACGCTGGGAACTGCCAAGACTGAGGGTCCCGGGATACCCGCAACGGTTACCAGCGCTAGTCGGGTCGTGGTCCGTACCCCGTCCCCTCGGAATTCTCCACCCAAGTCGCCTCCTCCTCCGACGTCCGCCGTTTAG
- Protein Sequence
- MRSLPWVRKYLRDEKWGITGRLFAQGAKFPRKPCYSPRKSNISAPTSANQVLSQVLHHFFAVFFNNTLGPPGGLLRSSFVPVIGSRYRLSRTLFLQLLVEIGPPVSSLRIEDTCGLTGRKTGRDSVRVCSQTGGEMENHLHVQWKHHQEGVLKFLEELQATETFVDVTLCCEGQRLKAHRVVLSACSPYLQQVLVDNPGEHATIILHDIGAEEMRSLLRFMYSGSASLPRRCLRAFLRAAHALQISVLMPGFEHALTEEIPRHHQGRQGPEEGATDSVPPPPLSTRPSAPEVMLPHDLSTSSSSGAKTELHYGSSHEDGSKRRRHFASGMTARSPEVHPASVYRSEDSWGNAFREGLMDHSSIPPRPTLVPPRPTPVMKSPWSQRLGSAAPPWRTSSVIAPVRPPTPPPLPPRVEPMDLLTVPGMTPDTRKPYCCPSPFCPSPSSTSSAYSSACSWAPQSPSALPTSRPPSLLSVPNKIHTAESPAEGTAALAIATADLRTLSPNPGPVPNPTNPSTPTTQPSPPPSPSRFTLKQRRLRDFYRSLQSTGNTSADDSQSSDKQLGNPSMETKDEDSLPVPASPLEPTSPSRPQWPSESPVAVEQSVIRLSKKSAFQPPLIVVSPPQSTPETSTSGTFNTRDEDKRPPLPTLMPTLVVHPPASPNGASPQGSPAAKSPSSSSGPHTCETCGKTFGRRQLLEQHRRTHTGEKPFECSVCGKSFTQRGHWSVHQRLHDGSRPHICPVCGKAFVSRASLKVHHRTHTGEKPFRCEDCGKQFSQLRNFKYHRSVHEGTREFACTCPECGKQFNDRGYLSSHLKIHRNRKEYACEHCEKRFNQRVAYNMHVRIHTGEKPHECEECGKRFGRKMLLRQHARTHTGERPFRCAVCGKAFADRSNMALHARLHSGEKPHSCDLCGKAFTKKHHLKTHMNFHTGVKPYACQRCGLRFSQSSNMRTHAKKCTAEAGSAAAGSATGTPETPSDSQGSLTPGLATNPEQQMMLSPGEPKIGPAETLGTAKTEGPGIPATVTSASRVVVRTPSPRNSPPKSPPPPTSAV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00261369;
- 90% Identity
- iTF_00797253;
- 80% Identity
- iTF_00797253;