Basic Information

Gene Symbol
su(Hw)
Assembly
GCA_037158775.1
Location
CM073776.1:96791246-96822553[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.00011 0.091 15.9 1.7 2 21 160 179 159 180 0.94
2 13 3.8e-06 0.0032 20.5 1.3 1 23 388 411 388 411 0.97
3 13 3.4e-05 0.029 17.5 0.8 1 23 417 439 417 439 0.96
4 13 2.7e-05 0.022 17.8 1.9 1 20 445 464 445 466 0.96
5 13 3.6e-08 3e-05 26.8 0.4 1 23 477 499 477 499 0.98
6 13 0.00041 0.35 14.1 1.9 1 23 509 531 509 531 0.99
7 13 1.5e-05 0.013 18.6 0.7 1 23 537 559 537 559 0.98
8 13 2.7e-05 0.023 17.8 1.0 1 23 565 587 565 587 0.99
9 13 1.3e-06 0.0011 21.9 2.5 1 23 593 615 593 615 0.94
10 13 9.2e-05 0.077 16.1 3.7 1 23 621 644 621 644 0.96
11 13 9.1e-07 0.00077 22.4 0.5 1 23 650 672 650 672 0.94
12 13 3.4e-07 0.00029 23.8 1.3 1 23 678 700 678 700 0.98
13 13 1.3e-06 0.0011 22.0 1.9 2 23 707 729 707 729 0.96

Sequence Information

Coding Sequence
ATGCCCGACACCGAAAACGCATCTGCTGCTGAAGTTGCAAAAGAGGCCGGCAAGAGTAAGAGGACTCTGATCGATCACTTTAAACCGATGCCACGCACATCTAAAAAGCAGGTAGTTCAGGAGCCAGTGGCAGCAGTTCCTGAGCCACCTGCTGTCCCGGAGAGTGATGGAGGAGCTCCACCAGCAAAGAAGAGGGGCCGGAAGCCAGGGCCAAAGAAGGCCAGCAGTGAGGCCGCGGGGAAGGTGGGGAGCGGCAAGGATAACGGAGGGGGGGCCGAAGTGAGCGGTGGTGGCAAGAAAGCTGACAGTGGTGTCAATGGAGTTTATGAAAACATCATTTGGGCTAACTGTGAAGGTCCCAAGACTGCTCGTGGACCTGGGAAAAGAGCAACAAATCCCAACAAAGAAGCTGAGACTTCATTGGAAGAGACTACTGAGGTAGCAACTGGTCCAAATCTAACTTACCCTGGCGACCTCAAGTGTGACTCCTGTCAGAGAACATTCAGTAATTCATCGGGTTTCAAGCGCCACCTTAAGTTTTGTTTGGACGCAGAGGGTCCTCCAGTTATAATGAAGATAAAGAAGCCTGGAGTGAGCCCTGTGGTGAATGGTGCTGTGGGTGGCGGCAAGAGGGTCACCCTCATCGATAAGTACATGTCCAAGGTGaaaggggcgagagaggaggggggtgaTGAGGTGACCAcagggggaaggaagaaggcagcGGGCAGTGGTGGAAGGACAAGCATTCAGGGGAAGCTGGACACATTTGGGTTTGTGGATGGCCGAAGGAAGAAGGGGGCTGAATTGGTGGAGAAGGCCAGTGGAGACGTGGGGGGGCGGTTCccgagaaggggtgggaggaggggcgcCAGGGTGGCCGTGGAGAgtgagaaggaggaggaggatgaccCAGATGATTTTGGGGACATAGATGACTCTGAGGATGACGAGGGGTTGACGCTCAGCGACCTTGAGAACATGGAGGATGACGGGGAGTTGAGCGAAGGGGGGCAGGGCACAGAGAAGTCTTTGAGGGAGAAAATGAAGGATGTGATGTTGATCAAAGTGAATGAGCTAATTGATGAGACATCAGCCACTGCTCCTGGAAAATGCCACTGTTGTGGAGAGGACTTGGAGACAGCACATTCGGGTGGTGAGTTTGAATGTGATGATTGCGGGAAGCACTTCAAGCTGCGAGCCAGTCTTGACCGCCACCGGCGCGTGATTCATCTCCAGGGCGAGACACACGCTTGCCCCGAGTGCGACGCAAGGTGCCCGGACAAGGGCTCCCTAGCGAGGCACATGTACACCCACACAGGTCTCAAGCCTTATTCATGTGTCCGCTGTAAAAAGCAATTCAGCAGGAAATATCATCTTGAGAGGCATATTGTCCAAACAGGCTGTGATGGCAACCCCAAACCCACATATCCATGTCAGGTTTGTGGTCGAATGTTCAGCCGCAAAGACAACTTGCGTGAGCATCTGCGTGCACATGCAGGGCAagtgaagaggaagaagaaatactCATGCGAGTATTGTTTGAAGGAGTTCCATGGTACATCACTCCTACGCATCCATGTTCGGACACATACTGGCGAGCGCCCATTTGTGTGCGATTTCTGCCAGAAGGGCTTCCCGTCGTCGGGCGCCATGAAGAAGCACCGTCGCATGCACACGGGAGAGCGTCCCTACGAATGCAAGGACTGCTTCGCCAAGTTCTCAGCCAAGGAGACGCTGAACCgccatgcacgcacacacactggCCTCAAGCCTCATGTCTGCAACTACTGTGGGAAGTCATTCATCCAAGCATCACAGCTACGTGCGCATGTCTTCCACCACACAGGTGAGAATGGCTTTACATGTGACCACTGTGGGAAGGCTTTTAACAGGCGTGCTCGCCTTCATATGCACGTCAAGTATGTTCATGAAGGTGCAAGACCTTTCGAGTGCACCAACTGTGGGAAGACGTTTGTGCGCAAGGAAGACCTTGTGCGGCACACGGTACTTCACTCGGGAGTCAAAGCACATAAATGCCCTATATGTGAGAAGTCCTTTGCAATGAAATCTTCCCTGAAAATTCATCTTCTGACTCATACAAAGGAGCCACCTCGTTCCTGTGACGAATGTGGCCGAGCCTTCATCCGCCAGGACTGCTTGCTGCGTCACATGCGCTCCAAGCACCGTGAGATGCTGGAGGAGATCCTTGCGGAGGCAGAGAAGAAAAAGCTGCAACAGCAGTTGCTGGCAGCCACGGCAATGGCCTCGCGCATAGTGGTTCGTGGCGAGAGATCAAGAGGGGTCACCCATCTGGGTGACGATGACCTTGaggaggaagatgatgatgaaatggaTGATGTGCCTGAAGCAGGAGCAATAGATCGTGTGCTGGGAATGTCAGGATCAGACAGTGCCAAAGCTGGGGTTCTGCTTCAGCACCTAACAGCCATGGGGGAGACACCAGGTGCAAATCCCATGCCGCGGATGGAAGCTTCGGCATCATCTTCAAACACAAGACTTGGTTCCAATCATCACCAGGGTGGTGGGAGCCTCTCGGAGACGGCTTTGGCGGACTCGGTGAGGGAGCTCCTCACGCTGTTGGTGGATGATGCGACCCTCCGTGCATTTGGATGGCCTGATGCCCCTGTCGACAAGCTCCTCGAGGCCGTCATCAGAAGGTGTGGGCACCAGCCTGCTTCACCTGAGGATTACTCGAGGCCTTCAGATAGACTTAGGGAGAATGCAAAGCTGCTCTTCACTGTGGTGATTGATGACTCAGCCGTGAAAACACTGCTTAACAACCAAACAGTAGATGAGGTGATACTGCATGTTCTTCGGCTTGCCAAGTCATGA
Protein Sequence
MPDTENASAAEVAKEAGKSKRTLIDHFKPMPRTSKKQVVQEPVAAVPEPPAVPESDGGAPPAKKRGRKPGPKKASSEAAGKVGSGKDNGGGAEVSGGGKKADSGVNGVYENIIWANCEGPKTARGPGKRATNPNKEAETSLEETTEVATGPNLTYPGDLKCDSCQRTFSNSSGFKRHLKFCLDAEGPPVIMKIKKPGVSPVVNGAVGGGKRVTLIDKYMSKVKGAREEGGDEVTTGGRKKAAGSGGRTSIQGKLDTFGFVDGRRKKGAELVEKASGDVGGRFPRRGGRRGARVAVESEKEEEDDPDDFGDIDDSEDDEGLTLSDLENMEDDGELSEGGQGTEKSLREKMKDVMLIKVNELIDETSATAPGKCHCCGEDLETAHSGGEFECDDCGKHFKLRASLDRHRRVIHLQGETHACPECDARCPDKGSLARHMYTHTGLKPYSCVRCKKQFSRKYHLERHIVQTGCDGNPKPTYPCQVCGRMFSRKDNLREHLRAHAGQVKRKKKYSCEYCLKEFHGTSLLRIHVRTHTGERPFVCDFCQKGFPSSGAMKKHRRMHTGERPYECKDCFAKFSAKETLNRHARTHTGLKPHVCNYCGKSFIQASQLRAHVFHHTGENGFTCDHCGKAFNRRARLHMHVKYVHEGARPFECTNCGKTFVRKEDLVRHTVLHSGVKAHKCPICEKSFAMKSSLKIHLLTHTKEPPRSCDECGRAFIRQDCLLRHMRSKHREMLEEILAEAEKKKLQQQLLAATAMASRIVVRGERSRGVTHLGDDDLEEEDDDEMDDVPEAGAIDRVLGMSGSDSAKAGVLLQHLTAMGETPGANPMPRMEASASSSNTRLGSNHHQGGGSLSETALADSVRELLTLLVDDATLRAFGWPDAPVDKLLEAVIRRCGHQPASPEDYSRPSDRLRENAKLLFTVVIDDSAVKTLLNNQTVDEVILHVLRLAKS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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