Hcom025267.1
Basic Information
- Insect
- Hesperia comma
- Gene Symbol
- -
- Assembly
- GCA_905404135.1
- Location
- FR990021.1:18427120-18436304[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 7 0.26 30 6.1 0.2 2 21 1648 1667 1647 1668 0.87 2 7 2.4e-05 0.0027 18.8 0.3 2 23 1785 1806 1784 1806 0.95 3 7 0.00087 0.1 13.9 4.1 1 23 1823 1845 1823 1845 0.97 4 7 0.0043 0.5 11.7 4.2 1 23 1880 1902 1880 1902 0.98 5 7 0.18 21 6.5 9.3 1 23 1926 1948 1926 1948 0.94 6 7 0.0051 0.59 11.4 0.7 1 20 1972 1991 1972 1993 0.94 7 7 0.38 43 5.6 0.7 5 23 2354 2373 2351 2373 0.91
Sequence Information
- Coding Sequence
- ATGGATAGGCTGAATCAGTTGCGAGGCGATGCTGGCGCCTCGCGGGACTCCACGCTGGACACGTCGTTGCTGGGCGAGGGCTACGTGACTGCCAACGATGGTTCCAAATATTTTTCTCTCTCGGAGACTGATGCTAGCTCCACAGATTCCCCCTCAAAGGATCCCGCTGCAGATAGCGCGACATCGCACGCGGAGTGCATCATATCCAATTTGTCGCCAATTCCTAAAAAGAGTGAGTTGGACAGTTTCAAAATTGGCAAACAGATTGAGGCAGCAAATATTCTCTCTGGAGGAGTCAACATTTTCGATGATAATGAAAACTCTTATGATGGAGACGAGCTCGTAATAGATGATGCAGTGACGGAGGGTGATGATAAGCCAGCAGAAATAAAATTAGATCAAAATGAGGAGACATTTGAAAAAACTGATGCATCACCCGATGCAAACATGGAAGAGGCGGAAGCTGCCAGTCCGAGCAAGGACACAGAGGTGGTGCTACAGATTGATGGAAATAATGTGGATGCTATAGATATTGGTAATGGATTGTACTTGTACAGAAAGGACGGTGAAGAGGAGCTGGCTGCCGTACAGATACTGCAGGATAACCAGCAGCAACCAAACATTAAATTTCTGAAAGTGCGTGAAAATGCAGAGGGGAATCTGGAAGTCTATGAAGAAATTGAAATAGAAGTCCCTAAAGAAGTGCCTACAAAGGAGGGAAAACCAATTAAAAACACTCCCCATATACCTATCAAAGACATAAATAAAGTCAGTGAGCCCATTAGTAACAAAGTTGTTGAAAAGAAAATCCAAGCAGCACCAAAAGATACTCCAGCGGTTGAAGTGGAAGATTTGAATAAAGATAATTCTCATATAGAGTCTAGGACAGAAGTAAATTTAAACGGAAAAATGATGAAATTCAGTGAATCTCGAAAGTCTCCAGTAATAGGCACCTTTACTCCCATGACATATCATTCTACTCCAAATAAAGAGGGTATTCCGCTTACTAAAACTATGGTTGATCTTCAGTTGCATCCTAATAGGCATTCTGAAAATGTTAAAAAGACTATTGAAGTGCATACAGATAATTGCAAGCAAAAATTGATTGAAACACCGACTAAGAGTTGTAAAGATTCCGATGAACACAGCAAAAGTCCGGAAATTGGGACATCATCGAGTAAAGATCCGACAGATAATATAACTGATCATAGTGTAGAACAGACCAACCTATTATATAATAAAGACACAAAACAGGCATTAAGTGAAAACAAAACTGACGTAATAATTACGATGAAAGTAAATGAAGATAAGAAAAATAATGAGAGAAATTTTGAGAGTACTATTGATAACACAAAGACTGAAATAGTTGACATTAAAATACCTAGCATAACATTAAAGAAGCCTTCAGATATGACCTTTAATGAGGAGGGCGATACTATGAAATCACAAGTAGTAAAAACAACACCTAACGAGATGCCTTCTAAATTAACCACTGAGGTTGCTGTAACCAAAAATCATGATATAATCAAAGATGCTTCACAGATAGAAATTGCAGACAATAAAAATCGTAGTAAATGTACCACATCTGAAAATGTTAAAGTGTATGATAATATACCAGTAGATAATAATCCTGTTGGTGAAAAGAACCAAAAAAATGAAAATATCAGAAGTGATAAGGACGTTATACGACATGAAGAGAAAAATATAGATAGCGCCTTTAGTAGAAGTCAAAATATAACTGATGTTATTGCAACTAAGACTGTCGTAAGCCAGGCAGATAACTCAGAGAATCCTATAAAAACAACGGAAAGCATTACTTGTAATGCAACACAAAAGAATAAATATGTCGACCAATCGCAAAAAGATTCTGAAATGAAGGAAATTTGCAATCAAAAGAAACTGATTCCTTTAGAAAAATTAGAAACTTCTTCAAAGTCGAAAGGTAACCCAGAAATGAAAGAAATTAGCAAACCTTTTGAAATATTATGTAGTTCTACTAAAGATATAAAATTAACTACCAATATGGCAATAAAAGATTCTAAAGTTCAATGCGATTTAAAAAACTTGTCTGGTGTAACACTAAAATTAAGTAGTCAGTCTGATAGTCAGTCTGTCTTAAAACCTGCTGAGATAAAAACTGATTCTGTATTGCCTCAAGCTGAGCAATCTGTAAATTCGGAAGCAAAAGAATGTAAAAGTGTTTCTGAGTTGAAAAACCTGGACAAAACCTGTAAAATCCCTAAATTTCAAACGGAACAAATCAAAAGTAATACAACGTTAAAACCTTTCAAGAATGAAAATAAACTTGATTGTCAATCATCAAGTAGTCTTAAAGTAGATAATATCACTAGGGTAAATGAAATGGAAATTGAAAAGAAAAGTAATTCAGACAAAATGTCGAAGGAGTATGTCAAAAAAGTTGATGGAAAATCGAATCAACTAGAAAGTATATCCCCCAAAGCAAGCACGGGTACTCCTAAATCTGCTATAAATGAAGACATGGACTTGAGCAAAGATTCGTGTACTAATAATCAAAGTTCTAGCCGTAATTCCTCATTATTAAACAAAGACACCACAGATAAAGTGGAAATACATAAGAAAAATGAACTTAAGCAAAAGTTACCCACGGCTTACAAAAATACCAAAGTTGCTTTGCGTACTTCAGAGTCGAAAATCCCTCATGCTAGCCAAAATATATCAATTGATGCTGAAAAATCTAAAAACGACACCAAAAAAGACCTGTCTAAAGTAAGCAAAGTTTCTGTAACTAAACCAATTAACAATAATAAAGCAGCTGTTCCATTTGGAATGTGGACTGAAGCTAACAGACAGGAATTTTTGAATAAAATAAAAGAATCTAAAGTTCCAACAAATACTTCAAATACAAAACAACTGAAGCAACCAAACGATTTGAATAGAAGAGACGTACTTCAAAAAATTGACAGCCAGAGACAGTCTAATAACGCATCGACCAAAGTGCAAGAACTAAATATTCTAAACAAAATGAAATTTAAGAATGAAACACAAGCCTTTGCAAGTAAATCAAATGTAAGTCAAAAGGAAAAGTTAAAGGACAATAAAATGTTAGCTCCAGTCTCAAAAGGAGAGGAATCGGTTTCTGATACTCCTATACTTGGTAATAAAGTTAATACAGAACAAACATTACCGATTATTTCTGTCGATATATCGAGTTCGGCTTCAAGTACTAAAAAAGAATCAGTGCATCGTAAAGAAATCAATAATCAGGATCTCATTGATAAGACTATTGAGGGTATTATAAATAGAGCAGTCACGGCAAAACTAGGCACAGAGGATGGAAAACAAGATAACGAACCAAAAGAGAAACCACATTGTGTTACATCTTACACAGGTGTTTCGCTCGACGAAATTGAATCAAAAATGAACGAATTGCACGGAATCCCCTTTGTAGAAAGACCACCTCATGAACTACCAAAAGTTTTTGAAGTTTTTGAACATGAAAACAAAAGCGGTGTAGCATCAGATGTGTTATCTGTCAATAAAAGTAGTAAATTACCTAGCAGTAAGCCTAATAACACTCAACAAAAAAGTCAACAGAAAGTAAATCAACCTGTTGATACTAAAGTTAATGAAGAATCTGATGAAGAAATTATAGAATATGAGCCTGTTACAGGCGATATACAGTTGAATAAAAATAGCATGTCATGTCAAGCGACAGTAAAGGATAAAATGAATTCTCAAAAATCCACAGCCACTAAAATAAATTGTGATTCTAAAAAAGAAAAAATCATTACCGAGAATGAATTCGATAAGTTTGCCAGAAGAAATTCAATTACCTATGAAAATTGCCTAACAGTAAATTTTGATGGCAAAGAACATCACAACGTAGTACAAACTGTTGTCGAGAAGGAGGCTATGCCTAAGAAATTATCGAGAAACGAAATAATGTTAGCAGAGTCAAAAGCTAAATCGCATAAGCAATTAGCTGGGCGCCAAATCAATTTCTCTAGTAAGATTCCAACCATGACAAAGGCAACACAGGATGAAGATTCACTTAACAAAAGTTACCAATCCAAAGTACAACTTGCTTATCAGACGGTTATGACAGCTAAACGTCAGCAAGAATGTCCTATAACTATAATAGAGGACAAACCTGTTAAAGTAGTTTTCATGGACGGAAATCACGAGTATACTCCACATCAGCTCAATGTTCAAGGTAAAGAGTTATCGCCGCCTAAGAAATCTGTAACCGAGTGGGATCATTTTACGCATAGTAACTCGGAATCATTAGACTCGGATATCTTGGACTCTGGCAACGATAGCAAATCACAAGATGATATTAAATTTAAAAGTAAACATCAAAGAAAACAGGTTCTTACTCCTGTTGAAGCGCCTGAATTGGAACTTATTGAGCCAAGTGACTTGGGTATTGAAGTTTCTCCAAAGAAAAAGCGTAAAGTTGAAGACACCAAGTTGGAAAAGAGTTCTAAATCATTAGTGCCGAAAAAAACTTACCTTCTGAATAGAAATATCACAATGGATGATGCACCTACTAACTCTCAGGATTCGACACCACCAAAAGAATCAGTAAACCAGCAAGAGGTATTTGTTGCTCATAAGGATTCTATATCAGCAATTGATAATTTGGTTAAAGCTGCGGAGCTTCTTGAAACTCAATCTGAAACTAAACATAGCTTACCACTAACTGACCAGAATTCAGTTGTTCAACAAAATAGCCCAGTAAAAAGGGGTAGAGGTCGTCCTCGAAAATACCCTCTTCCAGAACCAGGGTCCGACAATAAAGTTGCTAGCCCGACAAAGACGCCTACTCCACAAAAGAAACCTCGATTGATAGATGCTAAGGCTCCAAAACATGACACTGATTCTGAAGATGATGAAATTAACAGTGATGGCGAATTGGTTAAAGAAAATTGGACGATGGGAAAAATAAATGAAAATATCGTTTGTCCAATTTGTAATAAATTATTCCGTTCAGAAAATGTAGTATTTAAGCATGTAAAGCATTGCACTGGTCCTTCTCCAAGTAGATCTGACTCTGATAAGAGGAGCCCCAGAAGAATGAGACAGTCACAAGAATTAGATTGGAAATCGGAGGGAAGTAAATCAGATGGCATGGATGTCGATGAAGATTATGAAATCAATAAACCAGCGAAAAAAAGGAAATCAAACGTAAAAAGGTCTTCACACGATAAAAAATCTGATGATAAAATTGATGTCATTGTAATAGAGGATACTCCCGTTAAAGATAGGGAGTCACCCGTTAGAAAACGTGAGAGGTTGAAAAATGACTCAAATAAATCAATTATTAAACCGAAAGCGAAAACAGTAATGGAACATGGAAACAGTAACCTTGTATGTGAAATTTGTGGTAAAATGTTTAGGCAGCTGTCTTACCTGGCCAATCACAAGTTGCAACATAAAAATACAGAGCCAAAAAGTGAAAAAGATCAAATTCATAAATCACTTTTCAGTTGTGAAATTTGTAAGAAAGAATTCAGGAAACTACATCATTTGGTACAACATCGCATTATTCATAATCCAATTTCAATAAGAACCTTAAGAAAAAGTTCATCGGAACAAACAGATAACAAAACAATGAAAGATGCAGCTAAGCCAACTGAAGATCAAAGTGCAGGATTTAGATGCGAGCCTTGTGATAAATCTTTCCGAAAATTACATCACCTGGTAGAGCACAGGGAAACCCACGTTGAAATCAATAAAAAATGCAATCCAGTAACTAGCACTACTATTGATACAACGAAGCCAACTCCAGTTCATCACTGCGATATTTGTAAAAAGACATTTAAAAAGTTGCAGCATTTAATTGACCATAAGGAACATCACCTAGATACTAGTTCTGAGAAATCGGATGACAAAAGTGTAAAAAGTTCGTTATCGACGAAGGACATTATACATGAATGCCCATTATGTTATATGGTGTTCCCCAATGAACATTCATTGAACAAACATCACATTATATGTCAACGGAAAAAGAAGCAAACTGCTGCAAAACAAGCCAAAAAAAGTGATGTGAATGATGCTGCTGAGGAAGATGATGGAATTAAGGTTACCGGAGCAGGTGATGAAAATTTAGCTATACTTGAAGAAAAAGCAGACGTTGATACATCCTGTGTTTTAATTGAGGATGAAACACCCGTTATTCCAGAAAATCAGGATAATCATTTAACAGAAGTGACTAAACCCTTAGAAAAGAAAAAAGAAATAGACCTAAGTAATCAGATAATAACAACGAAGATTGACGAGGCGATTAAGTCTGAGGTTGAAAGGAAAACAGAAGATCATGAGAAACTGAATAAATCGACAAATAAGAAAGATGGCTATGAACGTAATGCTGATATAGTTTCAGTAAAATCCAAGAAACATGTAGTACCAACAACAACCCCGGTTGAAATCATTAAGATTCCAGATACGCCGACGCCTAAAAAGAAGCATCTCGCTAAAGATAAAATAGGGGTATCAGTCACTAAACGGCAAAAAACAACCAAAGCTTCCTCGCCTGTGGTAGATGCAATAAAAACTCAAGATTCAAGTGACGATGACGAAATAAGGTACATGCTAAACCCAGACTTCAAAATAGAAGAGTCTAACGAGGGGAAACTATTTATGAAGGTCCGAGCTAAGAAACGCAGTTCGCTGCAAATAGAAAGGCCAAATTCCAAAGACTTAATGAAAAGAAGAATTTCATTACAGCATCCTCCCAAAATACCCCGACTCAAAGTGAAACCAATTGTTGCACGTAAGCCGATAAATACTAATACGGTTACTAAAAGTTCAAGGAGTACAGTTATCCCATCTGAGCCGCCGGTATCGACAGATTCAGATGACAGCGACGTGAAGTACTCATTCCCTGTCGTTAAGGAAACGGAAAAGAAAGCACAAGTAAAAGTGAAAAAGCAAAAGATGGTTGAGAAAAGAAAATCATTGAGTAATATCGCAAAGAGGAAATCTTTAGGAAACTTAATCAGAGTTAAACAGAAAGTGAATGCATCGCCCGCCAAGCAGACTAAAAAACGAACAGCAGATGCAGAGCACCGCTGCGACTGCGGGCAGTTGTTCAGCAGCGCGGCGCTGCTGTCGCGCCACACGAGCTTGGCGCACACGCCGCCGCGCATCCGCCGCCGCCGCTCGCCCCCGCCCGACATACACCCCAAACCCGCTCTGAAGCGAACCAACAAACCTCCAGACACAAGGAAAACCATCAATCCCGCCTGCTCGAAAACCGGGGTCACCACGCCCGCCCCCTTGAAAACCGGGGTCACCACCCGGAAATCGAGCATCAACAGCGAAAAGACGACCGTCGAGGCAACCAAGACCTCGAAGACCACGCCCCTCGTCAAGACGCGACGCAGCACCGCCCACAAGGGAGTGCCGGTCCCGGAGAAAATGAGGAAACTCATGGATAAATCCAAAAAGTAA
- Protein Sequence
- MDRLNQLRGDAGASRDSTLDTSLLGEGYVTANDGSKYFSLSETDASSTDSPSKDPAADSATSHAECIISNLSPIPKKSELDSFKIGKQIEAANILSGGVNIFDDNENSYDGDELVIDDAVTEGDDKPAEIKLDQNEETFEKTDASPDANMEEAEAASPSKDTEVVLQIDGNNVDAIDIGNGLYLYRKDGEEELAAVQILQDNQQQPNIKFLKVRENAEGNLEVYEEIEIEVPKEVPTKEGKPIKNTPHIPIKDINKVSEPISNKVVEKKIQAAPKDTPAVEVEDLNKDNSHIESRTEVNLNGKMMKFSESRKSPVIGTFTPMTYHSTPNKEGIPLTKTMVDLQLHPNRHSENVKKTIEVHTDNCKQKLIETPTKSCKDSDEHSKSPEIGTSSSKDPTDNITDHSVEQTNLLYNKDTKQALSENKTDVIITMKVNEDKKNNERNFESTIDNTKTEIVDIKIPSITLKKPSDMTFNEEGDTMKSQVVKTTPNEMPSKLTTEVAVTKNHDIIKDASQIEIADNKNRSKCTTSENVKVYDNIPVDNNPVGEKNQKNENIRSDKDVIRHEEKNIDSAFSRSQNITDVIATKTVVSQADNSENPIKTTESITCNATQKNKYVDQSQKDSEMKEICNQKKLIPLEKLETSSKSKGNPEMKEISKPFEILCSSTKDIKLTTNMAIKDSKVQCDLKNLSGVTLKLSSQSDSQSVLKPAEIKTDSVLPQAEQSVNSEAKECKSVSELKNLDKTCKIPKFQTEQIKSNTTLKPFKNENKLDCQSSSSLKVDNITRVNEMEIEKKSNSDKMSKEYVKKVDGKSNQLESISPKASTGTPKSAINEDMDLSKDSCTNNQSSSRNSSLLNKDTTDKVEIHKKNELKQKLPTAYKNTKVALRTSESKIPHASQNISIDAEKSKNDTKKDLSKVSKVSVTKPINNNKAAVPFGMWTEANRQEFLNKIKESKVPTNTSNTKQLKQPNDLNRRDVLQKIDSQRQSNNASTKVQELNILNKMKFKNETQAFASKSNVSQKEKLKDNKMLAPVSKGEESVSDTPILGNKVNTEQTLPIISVDISSSASSTKKESVHRKEINNQDLIDKTIEGIINRAVTAKLGTEDGKQDNEPKEKPHCVTSYTGVSLDEIESKMNELHGIPFVERPPHELPKVFEVFEHENKSGVASDVLSVNKSSKLPSSKPNNTQQKSQQKVNQPVDTKVNEESDEEIIEYEPVTGDIQLNKNSMSCQATVKDKMNSQKSTATKINCDSKKEKIITENEFDKFARRNSITYENCLTVNFDGKEHHNVVQTVVEKEAMPKKLSRNEIMLAESKAKSHKQLAGRQINFSSKIPTMTKATQDEDSLNKSYQSKVQLAYQTVMTAKRQQECPITIIEDKPVKVVFMDGNHEYTPHQLNVQGKELSPPKKSVTEWDHFTHSNSESLDSDILDSGNDSKSQDDIKFKSKHQRKQVLTPVEAPELELIEPSDLGIEVSPKKKRKVEDTKLEKSSKSLVPKKTYLLNRNITMDDAPTNSQDSTPPKESVNQQEVFVAHKDSISAIDNLVKAAELLETQSETKHSLPLTDQNSVVQQNSPVKRGRGRPRKYPLPEPGSDNKVASPTKTPTPQKKPRLIDAKAPKHDTDSEDDEINSDGELVKENWTMGKINENIVCPICNKLFRSENVVFKHVKHCTGPSPSRSDSDKRSPRRMRQSQELDWKSEGSKSDGMDVDEDYEINKPAKKRKSNVKRSSHDKKSDDKIDVIVIEDTPVKDRESPVRKRERLKNDSNKSIIKPKAKTVMEHGNSNLVCEICGKMFRQLSYLANHKLQHKNTEPKSEKDQIHKSLFSCEICKKEFRKLHHLVQHRIIHNPISIRTLRKSSSEQTDNKTMKDAAKPTEDQSAGFRCEPCDKSFRKLHHLVEHRETHVEINKKCNPVTSTTIDTTKPTPVHHCDICKKTFKKLQHLIDHKEHHLDTSSEKSDDKSVKSSLSTKDIIHECPLCYMVFPNEHSLNKHHIICQRKKKQTAAKQAKKSDVNDAAEEDDGIKVTGAGDENLAILEEKADVDTSCVLIEDETPVIPENQDNHLTEVTKPLEKKKEIDLSNQIITTKIDEAIKSEVERKTEDHEKLNKSTNKKDGYERNADIVSVKSKKHVVPTTTPVEIIKIPDTPTPKKKHLAKDKIGVSVTKRQKTTKASSPVVDAIKTQDSSDDDEIRYMLNPDFKIEESNEGKLFMKVRAKKRSSLQIERPNSKDLMKRRISLQHPPKIPRLKVKPIVARKPINTNTVTKSSRSTVIPSEPPVSTDSDDSDVKYSFPVVKETEKKAQVKVKKQKMVEKRKSLSNIAKRKSLGNLIRVKQKVNASPAKQTKKRTADAEHRCDCGQLFSSAALLSRHTSLAHTPPRIRRRRSPPPDIHPKPALKRTNKPPDTRKTINPACSKTGVTTPAPLKTGVTTRKSSINSEKTTVEATKTSKTTPLVKTRRSTAHKGVPVPEKMRKLMDKSKK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01082901;
- 90% Identity
- -
- 80% Identity
- -