Hcom027725.1
Basic Information
- Insect
- Hesperia comma
- Gene Symbol
- -
- Assembly
- GCA_905404135.1
- Location
- FR990015.1:17512661-17514339[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.019 2.2 9.7 2.3 1 23 90 113 90 113 0.93 2 10 0.2 24 6.4 0.0 2 23 140 162 139 162 0.95 3 10 0.0095 1.1 10.6 0.1 3 23 186 206 184 206 0.91 4 10 0.15 17 6.9 0.0 1 21 210 230 210 232 0.85 5 10 0.041 4.8 8.6 2.3 1 23 237 260 237 260 0.96 6 10 0.0025 0.29 12.4 1.4 2 23 268 290 268 290 0.95 7 10 5.9e-05 0.0068 17.5 1.3 2 23 298 320 298 320 0.97 8 10 0.0022 0.25 12.6 1.2 1 23 326 348 326 348 0.96 9 10 2.2e-06 0.00026 22.0 1.7 1 23 354 376 354 376 0.98 10 10 0.00037 0.043 15.0 2.6 1 23 382 405 382 405 0.96
Sequence Information
- Coding Sequence
- ATGTTCCTGGAGAAGTCATATGAAGTCGAAACACTCAGAAATCATTTAAGTGCACAACGTAAAGGTAAAGCGAAAACAGAAACACGAGTCACCAAGGTTGATAACACTTCCAGACTTCTTAGAAGGCGGCTGGTTGTCAAAACCGAACCCGTGAGCCAAAAGTATGATATGAAAGAGACGAGAGAACTAGACAAGCATCGTTTTAATATCAGGCAAATTCTGCAGTGCTCTAATGCAACTCCGATACGTTGCCGTGGTGGTATAGGATACGCTTGCTGTTTCTGCACCAACCAGTTCCCTGATCCCAGGGATTTGAAGAAACATACTTTGGAATTTCACGACGATAAGTCTAAACGGTTTTTCATGAAAGACAAGATGATGTTCTCGTTTCTTGTGAAACTTGATATAACCTCGTTAGAATGCAGAGTTTGTGACAGTCCCATCGATACTTTAGAACAGCTCATCGATCATCTGATGAAGGCTCACCAGAAAACTATGTTTACAGATATAAAGAACCACATAATGCCATTCAAATTTACCGACCAAGTGCTTAGGTGTATAGTTTGTCCGTCTATTTTCAGTACATTCAAAGCTTTACAAGAACACATGAACATACACTATCGAAATTACATTTGCGATGTATGCGATGCTGGCTTCGTTAACAAGAATATCCTTTTGAGTCATGCAGATGGTCACAAGACTGGGACGTTCAAGTGTGACTTTTGTGCGAAAGTGTATACTTCGCTTAGAAAAAAGAAATCTCACGAAAAGTCTGTGCACATACACGCGAACATGTTGAATAGGTGCGGTTACTGCAACGAGAAATTCAAAGATTATCGATCAAAAGAGAGACATTTGTCATCTGTACATGGTGTTGAGATGTTGCCGCGGAAATGTCAGGCTTGTGAAAAATCTTTCAGTACCAAAACAGCGTTGAGTGTTCACACGAGAAGAGACCATCTCATGGAGAGACGCCATGAATGTAAAGTATGCGACATGAAGTTTTTCCTGACGAATGAGTTAAAGGAACATATGGTGGTACACACCGGGATAAGGAAGTTTGAGTGTGAGGTGTGTCACAAGGCGTATGGAAGAAGAAAGACTCTTCGAGAACACATGCGGATACATGCGGATGATCGGAGGTTCAAATGCGAACATTGTGGAATGGCATTTGTGCAAAAGTGTAGCTGGCGCGGGCACGTTCGAGCGAAACATGGTGAAAAAGTATAG
- Protein Sequence
- MFLEKSYEVETLRNHLSAQRKGKAKTETRVTKVDNTSRLLRRRLVVKTEPVSQKYDMKETRELDKHRFNIRQILQCSNATPIRCRGGIGYACCFCTNQFPDPRDLKKHTLEFHDDKSKRFFMKDKMMFSFLVKLDITSLECRVCDSPIDTLEQLIDHLMKAHQKTMFTDIKNHIMPFKFTDQVLRCIVCPSIFSTFKALQEHMNIHYRNYICDVCDAGFVNKNILLSHADGHKTGTFKCDFCAKVYTSLRKKKSHEKSVHIHANMLNRCGYCNEKFKDYRSKERHLSSVHGVEMLPRKCQACEKSFSTKTALSVHTRRDHLMERRHECKVCDMKFFLTNELKEHMVVHTGIRKFECEVCHKAYGRRKTLREHMRIHADDRRFKCEHCGMAFVQKCSWRGHVRAKHGEKV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00288289; iTF_00970689; iTF_01438347; iTF_00971638; iTF_01439321; iTF_00167166;
- 90% Identity
- iTF_00971638;
- 80% Identity
- -