Basic Information

Insect: Hermetia illucens
Gene Symbol: ZEB1
Assembly: GCA_905115235.1
Location: NC:7513270-7529836[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 0.057 3.1 8.0 1.6 3 23 187 207 186 207 0.97

2 19 0.31 17 5.7 1.0 5 23 388 406 385 406 0.93

3 19 0.38 21 5.5 0.4 1 23 469 492 469 492 0.91

4 19 4 2.2e+02 2.2 2.0 2 23 508 529 507 529 0.91

5 19 0.001 0.054 13.6 1.6 1 23 536 558 536 558 0.98

6 19 3.6e-05 0.0019 18.1 5.3 1 23 564 587 564 587 0.97

7 19 1.1e-07 6.2e-06 26.0 1.5 1 23 593 615 593 615 0.98

8 19 0.00043 0.023 14.7 2.5 1 23 621 643 621 643 0.99

9 19 4.7e-07 2.5e-05 24.1 0.4 1 23 649 671 649 671 0.98

10 19 1.2 64 3.9 1.4 5 23 806 824 803 824 0.93

11 19 0.041 2.2 8.5 3.2 2 23 900 922 899 922 0.90

12 19 3.2 1.8e+02 2.5 2.6 2 20 938 956 937 959 0.84

13 19 0.0037 0.2 11.8 1.2 1 23 966 988 966 988 0.94

14 19 0.0013 0.071 13.2 0.9 1 23 994 1017 994 1017 0.95

15 19 0.0041 0.22 11.7 1.0 1 23 1023 1045 1023 1045 0.94

16 19 0.00041 0.022 14.8 3.8 1 23 1051 1073 1051 1073 0.98

17 19 0.0029 0.16 12.1 1.0 1 23 1079 1101 1079 1101 0.96

18 19 8.4e-05 0.0046 17.0 1.3 1 23 1107 1129 1107 1129 0.97

19 19 2.8e-06 0.00015 21.6 0.7 1 23 1135 1157 1135 1157 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	0.057	3.1	8.0	1.6	3	23	187	207	186	207	0.97
2	19	0.31	17	5.7	1.0	5	23	388	406	385	406	0.93
3	19	0.38	21	5.5	0.4	1	23	469	492	469	492	0.91
4	19	4	2.2e+02	2.2	2.0	2	23	508	529	507	529	0.91
5	19	0.001	0.054	13.6	1.6	1	23	536	558	536	558	0.98
6	19	3.6e-05	0.0019	18.1	5.3	1	23	564	587	564	587	0.97
7	19	1.1e-07	6.2e-06	26.0	1.5	1	23	593	615	593	615	0.98
8	19	0.00043	0.023	14.7	2.5	1	23	621	643	621	643	0.99
9	19	4.7e-07	2.5e-05	24.1	0.4	1	23	649	671	649	671	0.98
10	19	1.2	64	3.9	1.4	5	23	806	824	803	824	0.93
11	19	0.041	2.2	8.5	3.2	2	23	900	922	899	922	0.90
12	19	3.2	1.8e+02	2.5	2.6	2	20	938	956	937	959	0.84
13	19	0.0037	0.2	11.8	1.2	1	23	966	988	966	988	0.94
14	19	0.0013	0.071	13.2	0.9	1	23	994	1017	994	1017	0.95
15	19	0.0041	0.22	11.7	1.0	1	23	1023	1045	1023	1045	0.94
16	19	0.00041	0.022	14.8	3.8	1	23	1051	1073	1051	1073	0.98
17	19	0.0029	0.16	12.1	1.0	1	23	1079	1101	1079	1101	0.96
18	19	8.4e-05	0.0046	17.0	1.3	1	23	1107	1129	1107	1129	0.97
19	19	2.8e-06	0.00015	21.6	0.7	1	23	1135	1157	1135	1157	0.98

Sequence Information

Coding Sequence: ATGTACAAAACAATGTCCGCGGACATAGATTTCGTAGGTCTCTCAAATTTCGCCCTCAAAACTGAGTACGCTTCTGAGGAAGAGTTCCAGGATGACTCTTCAGATACCCAAGAAACTGAACATACCAGTCTGGATCCTTTGAACACTGACCAGGAGGCAAATTGTGGACGTATTTTGGTATCAATCAATCGGAAAATCACGCTAGTCTGTGGAGCGTGCAATGGTCGCTTCGATTATATGGAATCGTTTGGGAATCATCTGGAGAAGGTTCGATGCGACTATATGTTGCGGAAAAACGGCTGCGTTGTGAATGAGGATCTCGAAGCTGGGATCAATGGAACTCAAGGCGACGCTCCTTCAACAGGGTCAACAGCCACAGATGTGAACGCTCCATCACCTATAAAAAATACTGATGCTACGAAGTATAATATCCGTGCATCAAAAACTACGGTGGCAAAGGGGATTCAAAGTACAACCCGAGAACATCACCTCAAAAGCTCCTTGAAATCAAAAATTATAGCCACCCCAGAGCCAAAGCACGATGTGAAAAGAAACTTATGTTTAACATGCAATCGTCGAATGGAGTCAAGAGAATCCTTAATGCGTCACCAGAGATATCACAGGTACCTGTTTCGCAAGCAGCAGAAGCGCAATTTGGAACGCAACAGACAAGAAGATTCATTGAACGATGTTGTAATCAAGGAGGAGATTGTCGCCGAAAGATATGAAATTCAAGAACCAGAATTTCCGACATCTGCATATGATGAAGTATGCGCTACAACATCCGACGAGGTCGATACATCCGAATTCAGATCCCCACGATTGGAAAAAATTCCGTGTGAAGCAGCAGGACCACCAATTCCAAGTGAACCAGGGGAACAAACAATTATGAGTGAAGCAGATAAACATCCAATTCGGAATGATCCAAAGGAGCAACCAATTCCGAGTGCACCAAAGGAAGGCGCAACTCCGAGTGAGCCAAGGACACCAGAAATATCATACAATGAAAACGAAACGCGGTTGGTGGAAAGTTTATCCCCAAAAGAACTTGACAACGATTCAAACATTGTTGATACACAAAAGAGTATAAAGAGAGGAAAAGTAGAAAAGATTGTGTTTACCTTGAAACCTGAGTACGACGAAGAAAAAAACTTTTGTATCACCTGCAATCGTCAACTTGCCACGCTGGCGTCGCTTCGACGTCACAAGCGGGAGCACATAGTGAAGATTGAACATTGGAAGATGGCAAACGGATCGGCACCAATTGTCTGTTCAGAAAAATGTAAGCTTGACGGAAAAGGAGATGCCGCGCTGGACTCTTCAGAAAGCCTTCTGCATCAAAAAAGAATACGTAGTGCTACAATACGTAAATATTTAGACAAAATTAGTTTACCTGAAACTGTATTTACGTGCGACTTATGCGAACAGCAACTCCAATCAAGTTTTGGTCTAAAAAAACACGCTGTAATTCGGCATGGAGACGAGATTCCGAAGTCCCTACAAAATGATCCAACATATCTCAAATGTCGATTTTGTCACGAGGAGTTTGAGAAGCCAACACAACGTTATCTTCACGAAGGAACCCACCTCGGTCAACCGTCACCCTATCAATGTCCTTGTTGTCCAAAAACCTTCACCAAGGAATCGGCTCGCAAAGTACATATGGCTAGTCATATAGAAAATTATGCATTCAGTTGTCCAAAATGTCCGAAAAAGTGTAAAACTCGCGATAATCTCTACCATCACATTAAAAGTGTTCATGTTAAAATCAAACCGTTTTCATGTAAATATTGCGGAAAGGCGTTCAGTACGAGCACACATCTAGCCTCTCATATGATTGTTCATACGAAGAACATGCCTTATCAATGTGATATATGCCTAACCGGATTTCGCAAAATGTCGTATCTACGAACGCATAAGAGGAGACACGATAATCAACCGGACTATGAATGTGATCAATGTGGGAAACAATTTGTTACAAAGGACCAACTTCGAGATCATCTAGCAACACATGCTGACATGTCCGACGAATCTGAagCGCTAGCAGCAGAAGAAAATAAAGCTCACGAAAAAAGAGCCGTTTCTACTGAACCTGGAAAGGCAACCTCATTCAACACAAATACAGAAGAAGCACCATCAGATGCTGGTCCTAGTAAGCTACAATCCAAAGCAACAGACACTACTTGTGAGCAGAATAACCAAGAATGCACACCAcaggaaggagcagaactggaaTCGAACTGTAGCGCTTCATTGAGTAAAACAAATGAAGATCAAATAACACTAGAAAGCGATAGTGATACAGATGAAAGTAGCAAATGTGCAAATAAGCAAAAGAGCAAAATCAAAACCAAAGGTGAGCGACTTGTGTTCGCAGTTAAACCCGAGTTCGATGATGAGAAAAATTTCTGCATCACCTGCAATCGGCAATTACCTTCAAGGGAGACCTACAAACGTCACAAAAGATGGCATATCTCGAAACTCCACCGATGGAATATCGAAAGCGATTTGAAAGCAGGCAAGGAACCGAGAAAAATTGTATATTCTGATAATCCTAGCTTCGATGAGGAAAGAAAATTCTGCATCACATGCGATCGTGGAATGGACCCTACAGAAAGTTTTGTAGAACATAAAAAAGAACATACAAAAGAAATCCGTAAGAAACTAGGTATCATTAACACCTTAGAAGCCAGATTGCCTTGTGAATTCTGTAAccggaaatttcaaaaaaacttcTCACTGAGAAATCACCTTGTCTTGTGTCACGGAGATAGGATTCCCAAGTCTTTGCAGGACGATCCATCGTACCTCAAATGTCGATACTGCCACCAGCAGTTTGAAAAGCCAACGGAACGTCATATACATGAAGGACTTCATTCCTCTGAGATGGCACCGTATCGATGCTCAGAGTGTCCGAAAATTTTCACCACAAGCGCGGCTCGCAAATTTCACAAACGCGTTCATACCGATGAGCGTCCTTTCAACTGCCCGCACTGTCCGCTGACTTTTAAAGTGGATGAATATCTTTATCGCCACGTTCAAAACGTCCACGCCGGTGTAAAACCATTCCAATGTGAATATTGTCCAAGGTCCTTTTACTCGAAACTAGAACGAGCCTCCCACTCCATCACCCACACAAACGAGTCACCCCATCAATGCGACGAATGCGGTACCCGGTATCGTCGGCTGCAAACTCTACAACTTCATAAGAAAAGGCATGCCAACCAATTAGACCATAAATGTGAAGAATGTGGGAAGCTGTTTCTCAGTAAGGGTCAATTGAAACTCCATCGGATTGCACACTCTGATGTCTATCCTTTCCGTTGTGGGGAGTGTGGAAAACAATTTCAACGTAGGAAAACTTTGATATCTCATGAGAAGCTGCATAGAGACGAGAAAGGGTACAGCTGCACGATTTGTGGCAAGCAATTCGCTCAGGCAAGTGGATTGTATTCGCACAAGAAGACTCACGGTGATAAGTTGTAA
Protein Sequence: MYKTMSADIDFVGLSNFALKTEYASEEEFQDDSSDTQETEHTSLDPLNTDQEANCGRILVSINRKITLVCGACNGRFDYMESFGNHLEKVRCDYMLRKNGCVVNEDLEAGINGTQGDAPSTGSTATDVNAPSPIKNTDATKYNIRASKTTVAKGIQSTTREHHLKSSLKSKIIATPEPKHDVKRNLCLTCNRRMESRESLMRHQRYHRYLFRKQQKRNLERNRQEDSLNDVVIKEEIVAERYEIQEPEFPTSAYDEVCATTSDEVDTSEFRSPRLEKIPCEAAGPPIPSEPGEQTIMSEADKHPIRNDPKEQPIPSAPKEGATPSEPRTPEISYNENETRLVESLSPKELDNDSNIVDTQKSIKRGKVEKIVFTLKPEYDEEKNFCITCNRQLATLASLRRHKREHIVKIEHWKMANGSAPIVCSEKCKLDGKGDAALDSSESLLHQKRIRSATIRKYLDKISLPETVFTCDLCEQQLQSSFGLKKHAVIRHGDEIPKSLQNDPTYLKCRFCHEEFEKPTQRYLHEGTHLGQPSPYQCPCCPKTFTKESARKVHMASHIENYAFSCPKCPKKCKTRDNLYHHIKSVHVKIKPFSCKYCGKAFSTSTHLASHMIVHTKNMPYQCDICLTGFRKMSYLRTHKRRHDNQPDYECDQCGKQFVTKDQLRDHLATHADMSDESEALAAEENKAHEKRAVSTEPGKATSFNTNTEEAPSDAGPSKLQSKATDTTCEQNNQECTPQEGAELESNCSASLSKTNEDQITLESDSDTDESSKCANKQKSKIKTKGERLVFAVKPEFDDEKNFCITCNRQLPSRETYKRHKRWHISKLHRWNIESDLKAGKEPRKIVYSDNPSFDEERKFCITCDRGMDPTESFVEHKKEHTKEIRKKLGIINTLEARLPCEFCNRKFQKNFSLRNHLVLCHGDRIPKSLQDDPSYLKCRYCHQQFEKPTERHIHEGLHSSEMAPYRCSECPKIFTTSAARKFHKRVHTDERPFNCPHCPLTFKVDEYLYRHVQNVHAGVKPFQCEYCPRSFYSKLERASHSITHTNESPHQCDECGTRYRRLQTLQLHKKRHANQLDHKCEECGKLFLSKGQLKLHRIAHSDVYPFRCGECGKQFQRRKTLISHEKLHRDEKGYSCTICGKQFAQASGLYSHKKTHGDKL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -