Hlin023376.1
Basic Information
- Gene Symbol
- -
- Assembly
- GCA_026182355.1
- Location
- JAPFBL010000074.1:104891-108513[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.00028 0.13 14.7 0.5 1 23 51 74 51 74 0.98 2 14 0.01 4.7 9.8 3.0 3 23 91 111 90 112 0.95 3 14 0.029 13 8.4 0.5 2 20 118 136 118 140 0.80 4 14 2.1e-05 0.0099 18.2 0.2 2 23 143 164 142 164 0.96 5 14 9.3e-06 0.0044 19.3 0.4 1 23 170 192 170 192 0.95 6 14 7.1e-06 0.0033 19.7 2.0 2 23 199 221 198 221 0.91 7 14 0.024 11 8.6 1.0 5 23 234 252 231 252 0.96 8 14 5.2e-06 0.0024 20.1 2.1 2 23 258 280 258 280 0.97 9 14 0.14 64 6.2 2.2 3 23 298 317 296 317 0.96 10 14 0.018 8.4 9.0 2.0 1 20 323 342 323 345 0.91 11 14 0.00012 0.055 15.9 1.0 1 23 353 375 353 375 0.99 12 14 2e-05 0.0094 18.3 3.1 1 23 381 403 381 403 0.97 13 14 1.6e-07 7.7e-05 24.9 1.3 1 23 409 431 409 431 0.97 14 14 0.022 10 8.7 8.0 1 23 437 459 437 460 0.95
Sequence Information
- Coding Sequence
- ATGAGTGCATGGAAACAAGTTTACAACCAGGATGGCTTGAACGTTGCGTTACCAGTTGGCCCTGTCTGGAAATTATCTGAACGAGTAACTCCAAACATTGAGAATGGCGTTGATCAAGAAAAGCCTGTGTTGCTGCCAACAGAACAAACTTATCAGTGCACTTACTGCAAGGTGGGTTTTGAAAACCCCAAGGAGAGACGGCTGCACATCTCTACTGTCCACTGCCCTAACGGGGATTCCAAAAAGAAGGTATTAGAAAGCAAAAGAGATTGTTCCAAGTGTGGTACGTTCTTTCTTTCTTTAAAAGATTTACAAAACCATAAAAAGGTTCATCATCCTGCATTGATTAGAAAGTGTTCTATATGTAATGAAGTTTTCCCCACAAAAGATAAACACGTAGAACATCTTGTTAATGTACATCCTCTAGAGTGTAATGTTTGCGGTAAGACTTTTACTAGTACAGCAGGAATGGCCCGACATAGTAAAATACATTTAGAAGTAAAACCCCACGCTTGTAACCTGTGTCCCAAGTCGTTTGTGTCTTCAGTAAAGCTTCAGGAACACATCAATGGCCATCTGGGTCTAAGTCCTCTTCAATGTAACATGTGTCCCCGAAAGTTCAGACGCTACTCAAATCTTAAGCAACATAAAGATTATGCTCATTTTAAAGTAAAAAAGAAGCTGAAGGATCATTTCTGTGATTGCGGGGAGTCGTTTTTAAGTAAAAAGAAGTTAGCCAGGCATAAAGAAACGCATCGGAGAAAGCCAAGACAGTGTCCTTACTGCGTCGAGAAGTTTGTACATACATCGAGCTTGACTCGTCATATTAGGAGAAATCACGATGCCAAGTATTTACCTCCGAACAGTAAGAGCAAATCAGTGAATGTCCATTGTCCCGTTTGCAACATGATCTGTCTGGCCTCTTCTCTCTCCAACCACCTTAAAAAGCACAACTCGAGCAAACAACACTCGTGTGTCATTTGCTCCAAGAAATTTCTTACCAAATGGAATCTTAAAATCCACAAGTGGACGCACGCTTCCCGTATATCAAAGCCATACAAGTGTAATTTGTGCAAAGGGGCTTTTATCAGATTCGGTGAATTCCAATCTCATTTGCGGTCTCACGTCGGGCATAAACCTTTTACTTGTAATCATTGCGGACTTCAGTTCATTCGGAAGCAGAATTGGAGAAGACATGAAAAAGAACATACAGGGACGAAAAAGTTTGCTTGCAACGAATGCGGCAAGGCGTTTCATCGAAGCTACTACCTAACGGAGCACATTCGCATCCACACAGGGGTGAAGCCTTTCATGTGTCACATCTGTAACAAGCTATCTGCGACAAAGTCAAACCACAACAAACACCTCAAGACCCACCACGCCCGGGAGACGGTCAACACTGAGGGCTGA
- Protein Sequence
- MSAWKQVYNQDGLNVALPVGPVWKLSERVTPNIENGVDQEKPVLLPTEQTYQCTYCKVGFENPKERRLHISTVHCPNGDSKKKVLESKRDCSKCGTFFLSLKDLQNHKKVHHPALIRKCSICNEVFPTKDKHVEHLVNVHPLECNVCGKTFTSTAGMARHSKIHLEVKPHACNLCPKSFVSSVKLQEHINGHLGLSPLQCNMCPRKFRRYSNLKQHKDYAHFKVKKKLKDHFCDCGESFLSKKKLARHKETHRRKPRQCPYCVEKFVHTSSLTRHIRRNHDAKYLPPNSKSKSVNVHCPVCNMICLASSLSNHLKKHNSSKQHSCVICSKKFLTKWNLKIHKWTHASRISKPYKCNLCKGAFIRFGEFQSHLRSHVGHKPFTCNHCGLQFIRKQNWRRHEKEHTGTKKFACNECGKAFHRSYYLTEHIRIHTGVKPFMCHICNKLSATKSNHNKHLKTHHARETVNTEG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -