Hlin044729.1
Basic Information
- Gene Symbol
- -
- Assembly
- GCA_026182355.1
- Location
- JAPFBL010000084.1:11586654-11592384[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 0.21 97 5.7 0.0 2 19 364 381 363 385 0.79 2 18 0.00024 0.11 14.9 0.9 1 23 391 413 391 413 0.97 3 18 0.57 2.7e+02 4.3 3.1 1 14 428 441 428 449 0.81 4 18 0.04 19 7.9 4.9 2 23 457 478 456 478 0.90 5 18 0.99 4.6e+02 3.5 4.0 2 23 486 508 486 508 0.91 6 18 4.4e-06 0.002 20.4 4.7 1 23 514 536 514 536 0.96 7 18 6.6e-06 0.0031 19.8 0.2 1 23 545 568 545 568 0.92 8 18 0.0024 1.1 11.8 1.5 1 23 578 601 578 601 0.96 9 18 0.026 12 8.5 2.8 1 23 619 641 619 641 0.95 10 18 0.00011 0.053 15.9 2.8 1 23 647 669 647 669 0.98 11 18 0.00078 0.36 13.3 0.7 1 23 688 710 688 710 0.95 12 18 0.61 2.9e+02 4.2 2.9 1 23 716 738 716 738 0.94 13 18 4.2e-06 0.002 20.4 0.4 1 23 755 777 755 777 0.99 14 18 7.4e-07 0.00034 22.8 0.5 1 23 783 805 783 805 0.98 15 18 0.004 1.9 11.1 0.3 1 23 811 833 811 833 0.98 16 18 0.00043 0.2 14.1 3.4 1 23 839 861 839 861 0.98 17 18 1.2e-05 0.0055 19.0 3.7 1 23 867 889 867 889 0.99 18 18 1.2e-05 0.0057 19.0 0.5 3 23 897 918 896 918 0.97
Sequence Information
- Coding Sequence
- ATGAAACTCATGTTAAAAAACACAACTGGTGAGTCGGTCACTCTTATAATTCGCCAAGACGACACATTCATTGATTTAAGAGAACGGGTTGAAGAAGAGTTGGGACTATGGTTAGACTTGAGTGATATTGTCAAAGGTCAAAACTACCTCGAATCTCAAAGAGTGCTGGATTTTTTTTCTCAATTAGCCTTTGCTGGTGAAGAGACGGTTCTACGTAATTGTGTATCAGATGTTGAATGTGTGGTACCAGGATGCCCAAATAAGAAGTCTGTAAATAGTGATAAAAGCTATTTTGAATTTCCACCAGAAGATATTAGGAATCATCAGTGGGCGTTATATTGTCAACGGCTTCTCTCAGGAACAGGAAAGAAAAGGTTAAATATTACTTCAGCTTCAAGGATATGTAGCGACCATTTCAAACCTGAACAGTTTGTAAAAAATACAACAACGATTTTAAAAAGAACTGCTGTTCCATGCATCAATCCTGATGTTACTAGTAAAGATGGTTTCTCCAGTTTGGTCACATACTCAGATCTAGTACATAAGAGCGATAAAAGGAGCCTTTTATGCCGTCTGTGTGCTCAGTCATCCAGTAATTATGTTTTCATATTTGATGGACAAGGAATGAAATTAAGTTTGGCAAATAAAATAAATGCTTGTTTTCCTCTTAATATTAGTATTCATGATGCACTTCCAAAACAAATTTGTTCTGTTTGTTATGACCAGTTGGAGGTTTTTTTTAAATTTTCTCAAGAAGCAGTTGATTCTCACTCCAGGCTTACTGCTGGTCATGGGAGATCTAGGTCATCCGTTCTGGCGTCTTATACTGATGAAGAAAACAATTGTGCCGTTACCATTTTAGCAGAAAATTCCGAACTGCTCTACTACGAGAAATGCCCATGTTGCAGAGAAGGAAACTTTTTTGATCCTTCCTCAATTAAAACTGAATTGCCTGACAATGTTCCTAGTGACAGTTTTGAAAAAATATCTGATAAAGGAAAATTACCTGTCCTTAAGGCGACCTGTCTTGAGGAAAACCCTGTTTATATTAAACCTGAACCAGATTCATCCACCCAAAGTACTAAATTAGTTTGTAACATTTGTTCCTTAGTTTTTAAAGTTCAAAGTGAAATTCTCCCACATTCTCTAATGCATTCTCAGGAGCATAACTACACCTGTAGCTTATGTAAAAATACTTTTTCTTCAAAGCCTCAACTAGTATCGCACTTATCAGAACATAACCTTTTTCCATTACAGCCGTGTGTGTTTACAGATTTGACTTATCAATGTGAAACATGTGGAATGGGATTCAAATCATTCCATATATTTTCAAATCATAATTGCACTTCCTTTACTTGGGTTTCTAACAAATGCAATGTATGCCACAAAACTTTTAGGTCTGAAAGCCGATTGGAGTTCCACAAAAAATTTCACAACAAAGAATCTAAACCAGGTTATTGTGATATATGTTGTAAAACATTTAGTGATGAGCTAAAGTTGTATAAACATGTAACGCATCTTCATGGGACAGGTAAAGTTCATTGCTGTGAAGAATGTGGTAAAGTTTTTAGATCCGTGAGTTCTCTCAAGTATCACCAACGTTCTCATCAGGGTGATTCCTCTATGAAACCTTATTCTTGTGATGTCTGTGGTAAGTATTTTATTAGAAGAAGCATGTTAAGAAATCATGTGGCCGCTGTTCATAAAACCTTAATAAACCAGACATCCTGTTTTTCTTGCACTATTTGCCACGAATGTTTTCCTAGCACTTATACAGCTGTGGCTCATATAGAGCGAATTCATAATGAAGCGTCAAGTAAAACATTATTCGATATGGTTTCAGTTAATAAAGTTTATATTTGTGAGTATTGTAGGCGTTGTTTTACAGATATTCTTTATATAAATATTCATAGAAGCAAACATCGAACTGATACACCCTATGAATGTAAATATTGCAACTTGGTATTTCAGACATGTGGAAGCCTAGAGTCTCATTACAGTACTCATGAGTCTGATAAAAATTTTACGGAGTATAAGTCAGAGTTCACAGTTCCTGTCATGTATCTTTGTGAATACTGTGATCGATCATTTATGAGCTCCATTAAGTACAACGAACATTTAACTGTTCACTATGGTCCTGTTCCATACGTATGCAGGTTTTGTGATGAAAAGTTTGCTACAATTCAAGAGTCATGTACTCACAGATCCACGCATGTAATGGAAGAAGACAGGAATCTGCCTGAAACTAATTTTTGTCGGCCTTATGAGTGTCATTTTTGTAATAAAGCATTTGCTATAGAAGATGCATTGATAAAACACATTAGAATGCACACTGGAGAAAAACCATTTATATGTGATCAGTGTGGAAAAGGCTTCTCACAAAGTTCTGGGCTTTACACTCATCAGAAAGTTCACTCCAGTATACGTCCGTATAGCTGTCCTCTGTGTCCGCGTCAGTTTAAAATTAAGGGTGATAGGGATGTTCATGTTAGAAAGcattctggtgaaagaccttataaatgtgaattttgcggtaaggctttcatgactcaacatgtatatagtcagcatcgtaagattcacaccggtgaacgtccatataagtgcgatgtttgtggcatttgttttaggaggtctcatgttcttacggttcataaacgaattcatactggggaaaagcctaatgcatgtgacatttgtgggaaACGATATCGTCAGAAAGGTGATATGTTAAAGCATCGTAGAATACAACACGTTCTTAAGATAATGAATCCTCTAGATTCGTAG
- Protein Sequence
- MKLMLKNTTGESVTLIIRQDDTFIDLRERVEEELGLWLDLSDIVKGQNYLESQRVLDFFSQLAFAGEETVLRNCVSDVECVVPGCPNKKSVNSDKSYFEFPPEDIRNHQWALYCQRLLSGTGKKRLNITSASRICSDHFKPEQFVKNTTTILKRTAVPCINPDVTSKDGFSSLVTYSDLVHKSDKRSLLCRLCAQSSSNYVFIFDGQGMKLSLANKINACFPLNISIHDALPKQICSVCYDQLEVFFKFSQEAVDSHSRLTAGHGRSRSSVLASYTDEENNCAVTILAENSELLYYEKCPCCREGNFFDPSSIKTELPDNVPSDSFEKISDKGKLPVLKATCLEENPVYIKPEPDSSTQSTKLVCNICSLVFKVQSEILPHSLMHSQEHNYTCSLCKNTFSSKPQLVSHLSEHNLFPLQPCVFTDLTYQCETCGMGFKSFHIFSNHNCTSFTWVSNKCNVCHKTFRSESRLEFHKKFHNKESKPGYCDICCKTFSDELKLYKHVTHLHGTGKVHCCEECGKVFRSVSSLKYHQRSHQGDSSMKPYSCDVCGKYFIRRSMLRNHVAAVHKTLINQTSCFSCTICHECFPSTYTAVAHIERIHNEASSKTLFDMVSVNKVYICEYCRRCFTDILYINIHRSKHRTDTPYECKYCNLVFQTCGSLESHYSTHESDKNFTEYKSEFTVPVMYLCEYCDRSFMSSIKYNEHLTVHYGPVPYVCRFCDEKFATIQESCTHRSTHVMEEDRNLPETNFCRPYECHFCNKAFAIEDALIKHIRMHTGEKPFICDQCGKGFSQSSGLYTHQKVHSSIRPYSCPLCPRQFKIKGDRDVHVRKHSGERPYKCEFCGKAFMTQHVYSQHRKIHTGERPYKCDVCGICFRRSHVLTVHKRIHTGEKPNACDICGKRYRQKGDMLKHRRIQHVLKIMNPLDS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -