Hlin036952.1
Basic Information
- Gene Symbol
- Ccdc103
- Assembly
- GCA_026182355.1
- Location
- JAPFBL010000036.1:4840987-4874063[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 0.0026 1.2 11.7 0.5 1 23 581 603 581 603 0.96 2 15 0.00049 0.23 13.9 0.5 1 23 621 643 621 643 0.96 3 15 0.011 5.2 9.7 0.7 2 13 647 658 646 660 0.88 4 15 3.3e-05 0.015 17.6 0.2 1 23 669 691 669 691 0.97 5 15 5.3e-07 0.00025 23.3 1.1 1 23 697 719 697 719 0.97 6 15 4.2e-07 0.0002 23.6 1.6 1 23 725 747 725 747 0.98 7 15 1.1e-06 0.00051 22.3 0.5 1 23 753 775 753 775 0.98 8 15 1.7e-05 0.008 18.5 0.1 1 23 781 803 781 803 0.97 9 15 4e-06 0.0019 20.5 3.4 1 23 818 840 818 840 0.98 10 15 5.6e-08 2.6e-05 26.3 2.1 1 23 846 868 846 868 0.98 11 15 0.00063 0.3 13.6 1.5 1 23 874 896 874 896 0.96 12 15 0.00014 0.066 15.6 0.5 1 23 907 929 907 929 0.96 13 15 5e-05 0.023 17.1 3.5 1 23 935 957 935 957 0.99 14 15 0.00014 0.065 15.7 5.0 3 23 965 985 963 985 0.96 15 15 0.0012 0.54 12.7 2.7 1 23 991 1013 991 1013 0.95
Sequence Information
- Coding Sequence
- ATGGGTGATAAAGATGTTCTTGATTTGAAGCTTTTTGAAGAAGAACTCATATCAGTTATTGCAGAAGACAAACTATACAAAGTTCAAAACGCTGCAAAAATTAGAGCTGCATGTGATCAAAAGGTGAAGTCTTATGACGAATTCCGAGATATAGTTAATGCTGCACACCTGAGGCCTTTAGACAAGTCTGATCGTATTAAAGCAGATAAAAAAACATCCGTTTGGAATCCTATTTCATCAAGGAGGAAAGTAGGCGACGTCAAAATTGGAAATACAATGGAACTGAATAAAGAGTATGGGGGACTGAACTGTGCTTCTGGACACAGTTCAAACTACTGTAGTGGAGAGTTAGTGCGAAGTTTAAGAAGACTTACGAATCCTCAAGACAGGTATACTGCTTTGATGTCAGCTGGAATATCTGAAATTGAAAGAGCCTTTAAGACTGAAATACCAGTTGGTCTGTTTGGGGAAATACTGGAAGCACTTGCAACTTTTCCACCAACAACTAGAGATGTCGTAGCTGTGGTTAAAATTCTAGAAACTCTTGCTTCTACTAAAAGGTTTACAATGAGTTTGGAGTTTCTGAGCTGCAGTGAAAAGTCCAAGGCTGTGGAGGTATTGGACAAGTTGTGCTGCAGTTTGAAGGACCGACAGCAAGATCTGGCAGAACAGGGTGTCACAGAGTATACTCTCTCGAGTCTCAAGGACAAGTACAGGATAACTCCTTTAGAAGATTATAAAAGAAAGTCTCGGAGTTTCTCATGCAGCAGATCTGATAGAAAAGTTGCGGCAAGTGGCAACTGCAGCAGGAACACCAAAACTTTTCATGCTGATACTAAAAGGGGAACTAGAAGAGGAGGTATTCTCGACCAGTCACTCGTTGAGGGAGCACTTAAGATGATGGAGGACAACCGGGTGAAGGGGGGCACCGTTCCATCTGGGCTTCTGTTCCAGTCTCCAGCAGGATCGGTATTTACTACTGGACCAGAGCATCAAGAATCAAACAGGATGAAGCACCAGTCTCCTGTCATAGTTACGGAAAAGGATGACTACTGCGTGAAATCCCCTTCCCTGGCTGGTGTTTCATCTGTTTTCCAGCCTCAAAGTCCCTCACCAACAATATTTACATCCTCTGCAGAACACCAGGAGGCTGATCAAAGAATGAAGCACCAGTCAGTCATCACGCAGGAAAAAGATGAGTACTGCGTCAAGTCGCCGTCCTTGCCAACAATATTCACATCTTCTGCAGAACACCAGGAGTCTGAACAGAGAATGAAGCACCAGTCAGTCATTACGCAGGAAAAGGATGAGTACTGCGTCAAGTCGCCGTCTTTGCCAGGAGTCCCTCAAGTTTTCCAAGCCCAAAGCTCAGGCTCCGCTATCTTCTCTCCTTCTCCCGATCAGGAGCCTGAACAAAGGATGAAACATCAGTCCGTCATAACGCAAGACAAGGATGATTACTGTATCAAGGCCTCGTCTCTCTCTGGTGTTGGTACTATTTTTCAATCTCAGAATGCGCCACCAACAATATTCTCCACCACTACCGACAACCAACCTGACCAGAGAATTAAACACCAGTCGGCTGGGAATTGCAAGATGTGCAATGTATGCCAGACATTCTTTGAGGAGAATGATATCCTTAAGCCGAACGAGTCGTGCGCTCTTTGCCTTCGTCATGCCAAGAGTGATAGGAAATGTGACTGCACCAGAGAAGACAAATGCACCTGCGTGGAGCGGGGTTTTTCTTGTGCCTATTGTGGAGATGTGTTTCCCACTACATTCCTGCTACAAAAACATACTTTTATTCACTGTCAAGACAATGAACAGAGTGCTGCAACTGGTGGATCACAAGAAGGCAATTTCACATGTCCATCTTGCAACTCCACGTTTTCATCGCAGGAACAACTGGACTCGCATGTAGAAAACCACAAACAATCAACCTGTCCTGACTGCAACAAAACATTTAAACATTTAGATACCAGCAGACATGCTTGTAAGGCTAGGTTTATGTGTGACTTGTGTGGTGCTGGTTTTGTCTCAAATTATAATTTAAAGATGCATGTTTTGAAACATTCTGGTAGTTTACCATATAAGTGCCGGCAGTGTGATAAATCGTTTTCTAAGCCATCAGAATTAACGCGTCATGGTTCTGTACACTCTGGTGAAAGACCTTTTATATGTCAGGAATGCGGAATGACCTTTACGAATTCTACTAATCTTCGAAATCATAAGAACACTCACAGTGGTTTAAAACCTTATCCGTGTAATATATGTAACAAAAATTTCACGAGGTTGGCTGATGTAAAAAGACATCTTTTGACACATACGGGAGCACGGCCGTTTGCTTGTGATTTTTGCGGTCTCGCTTTTGCAGATGCGTCAAATATGAAGAAACATCTTGGAACACATTCAAAGGGTTCCTTTAATCAAATCACTCATGACATGAAGACGTACCAATGTACATACTGCAGTAAGTTGTTTTCTCGGCCTTCTGAGCTCAAGAGACATTTTTTCACACATACAAATATGAGGCCTTACTCGTGTCATTTTTGTGGTCTCGCTTTCACCGATTCATCCAATCTGAAGAAGCACATCTTGACTCATTCGAGAGCCTCAGAGCACCGGTGTAACCAGTGCGATCAAAAGTTCGAAACTTTTGAAGACCTTGAGTCCCATGTTGTTAGTCATTCCAATGTTGCTGCCATACAGTCTGGCAGTCATCAGTGTGGAATTTGTGGAGCTGTTTTCACTCATCTTGTAGATTTACAAGAACATTCTGTCACCCATGGCAACACAAACACTTTTAAATGTGATATATGTTCGAAAAATTTCTGCCAAGAAATATTTTTACAGAGGCATTTGCTTACACACACTGAGTCACGGCCTTACGGGTGTACTGAATGTCAAAAATGCTTTAAATCACTTTCTCACTTAAGAAATCACTCCCTCATCCATACTGGAGAGAAGACTCATGTGTGTATGACCTGCAATAAGTCCTTCCTAAAAAAATCCTCTCTTCGTCGACACCTCGGAGTACACACCAGGGAAAAAGTTCACAACCTCTTCCAGGTCTTCGATCAAACTGCCATAAACACTGTTATTCAATGA
- Protein Sequence
- MGDKDVLDLKLFEEELISVIAEDKLYKVQNAAKIRAACDQKVKSYDEFRDIVNAAHLRPLDKSDRIKADKKTSVWNPISSRRKVGDVKIGNTMELNKEYGGLNCASGHSSNYCSGELVRSLRRLTNPQDRYTALMSAGISEIERAFKTEIPVGLFGEILEALATFPPTTRDVVAVVKILETLASTKRFTMSLEFLSCSEKSKAVEVLDKLCCSLKDRQQDLAEQGVTEYTLSSLKDKYRITPLEDYKRKSRSFSCSRSDRKVAASGNCSRNTKTFHADTKRGTRRGGILDQSLVEGALKMMEDNRVKGGTVPSGLLFQSPAGSVFTTGPEHQESNRMKHQSPVIVTEKDDYCVKSPSLAGVSSVFQPQSPSPTIFTSSAEHQEADQRMKHQSVITQEKDEYCVKSPSLPTIFTSSAEHQESEQRMKHQSVITQEKDEYCVKSPSLPGVPQVFQAQSSGSAIFSPSPDQEPEQRMKHQSVITQDKDDYCIKASSLSGVGTIFQSQNAPPTIFSTTTDNQPDQRIKHQSAGNCKMCNVCQTFFEENDILKPNESCALCLRHAKSDRKCDCTREDKCTCVERGFSCAYCGDVFPTTFLLQKHTFIHCQDNEQSAATGGSQEGNFTCPSCNSTFSSQEQLDSHVENHKQSTCPDCNKTFKHLDTSRHACKARFMCDLCGAGFVSNYNLKMHVLKHSGSLPYKCRQCDKSFSKPSELTRHGSVHSGERPFICQECGMTFTNSTNLRNHKNTHSGLKPYPCNICNKNFTRLADVKRHLLTHTGARPFACDFCGLAFADASNMKKHLGTHSKGSFNQITHDMKTYQCTYCSKLFSRPSELKRHFFTHTNMRPYSCHFCGLAFTDSSNLKKHILTHSRASEHRCNQCDQKFETFEDLESHVVSHSNVAAIQSGSHQCGICGAVFTHLVDLQEHSVTHGNTNTFKCDICSKNFCQEIFLQRHLLTHTESRPYGCTECQKCFKSLSHLRNHSLIHTGEKTHVCMTCNKSFLKKSSLRRHLGVHTREKVHNLFQVFDQTAINTVIQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -