Hmer013207.1
Basic Information
- Insect
- Hermaeophaga mercurialis
- Gene Symbol
- -
- Assembly
- GCA_951812935.1
- Location
- OX638361.1:16759590-16765588[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.00052 0.062 14.7 1.2 1 23 10 33 10 33 0.91 2 13 4.4e-06 0.00052 21.2 0.8 1 23 36 59 36 59 0.93 3 13 0.094 11 7.6 2.7 2 23 62 84 61 84 0.88 4 13 0.041 4.8 8.7 0.3 1 11 87 97 87 101 0.91 5 13 0.0024 0.29 12.6 0.3 2 23 110 132 109 132 0.89 6 13 0.00034 0.04 15.3 0.4 1 21 135 155 135 158 0.89 7 13 0.053 6.3 8.4 0.4 2 23 161 183 160 183 0.88 8 13 0.00034 0.04 15.3 0.4 1 21 186 206 186 209 0.89 9 13 0.053 6.3 8.4 0.4 2 23 212 234 211 234 0.88 10 13 0.00017 0.02 16.2 2.5 1 23 237 260 237 260 0.93 11 13 0.037 4.3 8.9 0.4 2 23 263 285 262 285 0.90 12 13 2.9e-05 0.0034 18.6 0.6 1 23 288 311 288 311 0.95 13 13 0.017 2 9.9 0.4 1 23 332 355 332 355 0.95
Sequence Information
- Coding Sequence
- ATGAAATGGCATCAACGAACTACACATTTTTCTTGTAATTATTGCACCAATAGTTTTGATTCTAAAAAAGAGCTAAATATCCATGAggctaataaacattttacttttgaatGTAACTTATGTGGCAGGAGGTTTAAAACCGAAGAAGATTTGGAACGacataataaagctaaacattATGTTGAGTGCAGTCATTGTGGTGAATGCTTTCTTTCTAATAGGAAGCTGGATAATCATGAACTTGAAAAACATTATGCTTTTGAGTGTAACATATGCGATAGAAAGTTTAAAGCAGAAGAACAACATAACAGAGCTAAGCATTATATTAAGTGCAATGATTGcgatgaatatttttattcttctaaggaGCTAGATATTCATGAACTTGACAAACACTTTCCTTTTGAATGTTTCATTTGCAATAAGAAGTTTAAATTAGCAGAAGATCTGGAACAACATAACATAGCTAAGCATTATATTAAGTGCAATGATTGcagtgaatatttttattcttttaaggaGCTAGATATTCATGAACTTGACAAACACTTTCCTTTTGAATGTTTCATTTGCAATAAGAAGTTTAAATTAGCAGAAGATCTGGAACAACATAACATAGCTAAGCATTATATTAAGTGCAATGATTGcagtgaatatttttattcttttaaggaGCTAGATATTCATGAACTTGACAAACACTTTCCTTTTGAATGTACCATTTGCAATAAGAAGTTTAAATTAGAAGAACATCTGGAACAACATAACAAAGCCAAACATTATGTTAAGTGCAATGATTGCggtgattatttttattcttctaaggaGCTAGATATTCATAAACTTGACAAACACTTTCCTTTTGAATGTACCATTTGCAATAAGAAGTTTAAATTAGCAGAAGATCTGGAACAACATAACAGAGCTAAGCATTATATTAAGTGCAATGATTGCgAGGCCCGTGATACCCATGAAGATGAAGAACACTTCCCTTTTGAATGTGGTGTATGTGGCTCGAGGTTTAAGGCAGAAAACAGCATGGAACAACATAAAAGAGATAAGCATTGTGTAATATTGTAG
- Protein Sequence
- MKWHQRTTHFSCNYCTNSFDSKKELNIHEANKHFTFECNLCGRRFKTEEDLERHNKAKHYVECSHCGECFLSNRKLDNHELEKHYAFECNICDRKFKAEEQHNRAKHYIKCNDCDEYFYSSKELDIHELDKHFPFECFICNKKFKLAEDLEQHNIAKHYIKCNDCSEYFYSFKELDIHELDKHFPFECFICNKKFKLAEDLEQHNIAKHYIKCNDCSEYFYSFKELDIHELDKHFPFECTICNKKFKLEEHLEQHNKAKHYVKCNDCGDYFYSSKELDIHKLDKHFPFECTICNKKFKLAEDLEQHNRAKHYIKCNDCEARDTHEDEEHFPFECGVCGSRFKAENSMEQHKRDKHCVIL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -