Basic Information

Insect: Hermaeophaga mercurialis
Gene Symbol: zfh1
Assembly: GCA_951812935.1
Location: OX638365.1:34545528-34555096[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 42 0.43 50 5.5 1.0 2 20 23 41 22 44 0.80

2 42 0.24 28 6.3 0.9 1 23 50 72 50 72 0.94

3 42 0.00055 0.065 14.6 1.3 1 23 78 100 78 100 0.90

4 42 2.5e-05 0.003 18.8 1.7 1 23 106 129 106 129 0.97

5 42 0.0075 0.88 11.0 3.8 1 23 141 164 141 164 0.96

6 42 0.00015 0.018 16.4 0.2 2 23 174 195 173 195 0.97

7 42 6.7e-05 0.0079 17.5 3.5 1 23 201 223 201 223 0.97

8 42 0.02 2.4 9.7 0.4 1 13 229 241 229 246 0.87

9 42 0.35 41 5.8 2.3 3 23 286 306 285 306 0.97

10 42 0.4 48 5.6 4.3 1 23 312 334 312 334 0.97

11 42 0.0048 0.57 11.6 0.5 2 23 338 359 337 359 0.95

12 42 0.0029 0.34 12.3 1.1 3 23 367 388 365 389 0.96

13 42 0.00085 0.1 14.0 1.9 1 23 400 423 400 423 0.95

14 42 1.7e-05 0.002 19.4 0.7 3 23 434 454 432 454 0.97

15 42 1.1e-05 0.0013 20.0 1.7 1 23 460 482 460 482 0.98

16 42 0.00038 0.045 15.1 0.5 1 23 488 510 488 510 0.98

17 42 1.2 1.4e+02 4.1 0.4 2 14 553 565 552 574 0.75

18 42 6e-05 0.0071 17.6 5.1 1 23 580 602 580 602 0.98

19 42 0.0062 0.74 11.3 1.2 1 19 605 623 605 626 0.90

20 42 7.6e-05 0.0089 17.3 0.2 1 23 631 654 631 654 0.94

21 42 1.1 1.3e+02 4.2 2.2 1 23 666 689 666 689 0.95

22 42 0.00068 0.08 14.3 2.2 3 23 700 720 698 720 0.97

23 42 4.4e-06 0.00052 21.2 0.4 1 23 726 748 726 748 0.98

24 42 0.0011 0.13 13.6 0.3 1 23 754 776 754 776 0.98

25 42 0.0001 0.012 16.9 1.6 2 21 783 802 782 803 0.93

26 42 0.00057 0.067 14.6 0.3 2 23 842 863 841 863 0.94

27 42 4.1 4.8e+02 2.4 5.3 1 23 869 891 869 891 0.98

28 42 0.018 2.1 9.8 2.4 1 23 894 916 894 916 0.97

29 42 0.00028 0.033 15.5 0.3 2 23 923 944 922 944 0.96

30 42 0.00019 0.022 16.1 2.1 1 23 953 976 953 976 0.95

31 42 2.8e-05 0.0034 18.7 0.2 2 23 986 1007 985 1007 0.96

32 42 0.00084 0.099 14.0 2.6 1 23 1013 1035 1013 1035 0.96

33 42 8.5e-05 0.01 17.2 0.7 1 23 1041 1063 1041 1063 0.99

34 42 0.024 2.8 9.4 0.1 1 16 1069 1084 1069 1085 0.91

35 42 7.6 8.9e+02 1.6 0.9 2 23 1131 1152 1130 1152 0.94

36 42 4.2 4.9e+02 2.4 0.9 1 23 1157 1179 1157 1179 0.96

37 42 0.003 0.35 12.3 2.5 1 23 1182 1204 1182 1204 0.98

38 42 6.7e-05 0.0079 17.5 0.7 2 23 1241 1263 1240 1263 0.95

39 42 0.00021 0.025 15.9 2.2 3 23 1274 1294 1273 1294 0.98

40 42 0.00014 0.017 16.5 1.9 1 23 1300 1322 1300 1322 0.98

41 42 1.4e-05 0.0017 19.6 3.4 1 23 1328 1350 1328 1350 0.99

42 42 8.1e-05 0.0096 17.2 0.4 1 21 1356 1376 1356 1377 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	42	0.43	50	5.5	1.0	2	20	23	41	22	44	0.80
2	42	0.24	28	6.3	0.9	1	23	50	72	50	72	0.94
3	42	0.00055	0.065	14.6	1.3	1	23	78	100	78	100	0.90
4	42	2.5e-05	0.003	18.8	1.7	1	23	106	129	106	129	0.97
5	42	0.0075	0.88	11.0	3.8	1	23	141	164	141	164	0.96
6	42	0.00015	0.018	16.4	0.2	2	23	174	195	173	195	0.97
7	42	6.7e-05	0.0079	17.5	3.5	1	23	201	223	201	223	0.97
8	42	0.02	2.4	9.7	0.4	1	13	229	241	229	246	0.87
9	42	0.35	41	5.8	2.3	3	23	286	306	285	306	0.97
10	42	0.4	48	5.6	4.3	1	23	312	334	312	334	0.97
11	42	0.0048	0.57	11.6	0.5	2	23	338	359	337	359	0.95
12	42	0.0029	0.34	12.3	1.1	3	23	367	388	365	389	0.96
13	42	0.00085	0.1	14.0	1.9	1	23	400	423	400	423	0.95
14	42	1.7e-05	0.002	19.4	0.7	3	23	434	454	432	454	0.97
15	42	1.1e-05	0.0013	20.0	1.7	1	23	460	482	460	482	0.98
16	42	0.00038	0.045	15.1	0.5	1	23	488	510	488	510	0.98
17	42	1.2	1.4e+02	4.1	0.4	2	14	553	565	552	574	0.75
18	42	6e-05	0.0071	17.6	5.1	1	23	580	602	580	602	0.98
19	42	0.0062	0.74	11.3	1.2	1	19	605	623	605	626	0.90
20	42	7.6e-05	0.0089	17.3	0.2	1	23	631	654	631	654	0.94
21	42	1.1	1.3e+02	4.2	2.2	1	23	666	689	666	689	0.95
22	42	0.00068	0.08	14.3	2.2	3	23	700	720	698	720	0.97
23	42	4.4e-06	0.00052	21.2	0.4	1	23	726	748	726	748	0.98
24	42	0.0011	0.13	13.6	0.3	1	23	754	776	754	776	0.98
25	42	0.0001	0.012	16.9	1.6	2	21	783	802	782	803	0.93
26	42	0.00057	0.067	14.6	0.3	2	23	842	863	841	863	0.94
27	42	4.1	4.8e+02	2.4	5.3	1	23	869	891	869	891	0.98
28	42	0.018	2.1	9.8	2.4	1	23	894	916	894	916	0.97
29	42	0.00028	0.033	15.5	0.3	2	23	923	944	922	944	0.96
30	42	0.00019	0.022	16.1	2.1	1	23	953	976	953	976	0.95
31	42	2.8e-05	0.0034	18.7	0.2	2	23	986	1007	985	1007	0.96
32	42	0.00084	0.099	14.0	2.6	1	23	1013	1035	1013	1035	0.96
33	42	8.5e-05	0.01	17.2	0.7	1	23	1041	1063	1041	1063	0.99
34	42	0.024	2.8	9.4	0.1	1	16	1069	1084	1069	1085	0.91
35	42	7.6	8.9e+02	1.6	0.9	2	23	1131	1152	1130	1152	0.94
36	42	4.2	4.9e+02	2.4	0.9	1	23	1157	1179	1157	1179	0.96
37	42	0.003	0.35	12.3	2.5	1	23	1182	1204	1182	1204	0.98
38	42	6.7e-05	0.0079	17.5	0.7	2	23	1241	1263	1240	1263	0.95
39	42	0.00021	0.025	15.9	2.2	3	23	1274	1294	1273	1294	0.98
40	42	0.00014	0.017	16.5	1.9	1	23	1300	1322	1300	1322	0.98
41	42	1.4e-05	0.0017	19.6	3.4	1	23	1328	1350	1328	1350	0.99
42	42	8.1e-05	0.0096	17.2	0.4	1	21	1356	1376	1356	1377	0.95

Sequence Information

Coding Sequence: ATGAACAGGATCACGGCCAGACACCCCCAACTCATAGCTCAACCCGTAGAACTAGAAGTTCCGTTGGAATGTAAGCGTTGCAACAAAGAGTTCAACAACAATATAGATTTCGCTTTTCACTCGAAAGAACACGACTCCGAAGGAAAGTACACCTGCCACATTTGCGACTACACGAATATCTCGAAACCGCCGTTCGACCTGCACATGCGCGAACACGAAGGCATACACAAGTACAAATGTCCGATGTGCCCGAAGACTTTTAAGCAAAGCAAAGACGCCGCGGAACACAAGTATTTCCACACGGGCGAGAAACCGTTCCAGTGCGAAATATGCGGCAAACACTTCCCTTACACGAAAAGTTTGGCCGCCCATCGGCGAAACACCCACTACGAAATCATAACGGGGAAACCCCTGCAAAAGTACGATTGCAAAGTTTGCAACCGGCACTACGAGAGCCACTCGGGCCTAGTGCGGCACTACTCGTCGAGCCACAAGGAACTCGGCTACGATTACTCGGTGGTGTGCGACATTTGCGGCAAAACCATTGCGACCAGAAACAAACTCAAGTACCACTTGCGGGTTCACACGGGGTACAAACCCCACGAATGCAACGTGTGTCACAAAGGGTTCTCGAAGAAGCAAGAGCTGAAGATCCACGAGAGGGTGCATACGGGGGAGAAACCGTTTACTTGCTCGTATTGCGGGAAAAAGTTCGCCCAGTTGGCTCCGTACCGGAACCGcaagaaacagaaaaatacGAAGACAACCAAATCCACCAATAAAATCCCCGAACCCGAGATCGATGAAAAGCTCACGAAACTGAGCTCCATACTGAAAATCGAAAAACCCTTGTTGTGCTCCTCCTGCCAAAAAGCCTTCAACTCGCACTTAGAACTCGCCTATCACTCAAAAAAGCACAACGAATCCAAAATGCACACGTGCCACTTGTGCAACTTCACCGTAGCGACGAAATTCCGAATAAGAAGACACATCAACGGACACGCGGGCTGGAAATGCCAAATGTGCAACAAGGTGTTTAGGAAAGCCAGGGCGGCGTTGAAGCATTGGTACATGCACACCGGTGAGAAAATGTACGGTTGCGAAATTTGCGGCAAACACCTCGCTAACGCTAAAAGTCTGGACACCCACCTTAACACCATCCACCACGAAATAATAACGGGCAAGCCTCTAGTCAAATTCGATTGTCCCATTTGTAAGAAACACTACGAGTCCGAGACGGGGCTGAGGAGACACTATTCCAGTTCTCACAGAGAAATGGGGGTGGACCTCACGGTGATCTGCGAAGTATGCGGAAAGAGGATTTCGAATAGAACCAGGTTAACGAGACACATGAGGACGCATAACGGCGAAAAGCCGTTTCCTTGTTCGATTTGCGAAAGGAATTTCGCCACGAAGTGTTTACTTACCTCACACATGAGGGTGCACACCGGTGAGAAACCGTATATTTGTTCGTTTTGCGGGAAACGGTTCGGCCAATCGGCTCCTTACAGATATCACATTAAAATACACACCGGGGATCGGAGataCGTGACAACGAAACGAAAATACATCAAATCGAAACGCCAAAAGAATTACAGGTTCATCaaagaaaaggaaaacaaaatcaAGAATCTACTCGTGATGAACGAACCGATGCAATGCCCGGTGTGCAAACAATCCTTCCAAAACCTTTTAGATTACGCATTTCATTCAAAAAGCCACGAAACCAACGGCTTCTACTCCTGCCACGTTTGCGGCAAAAAAGTCACTCACAAAAAACAATTCGAACGACACATTTTGTCCCACAAAAGCTTCAAATGCGAAGTATGCAACAGGGTTTTCAAAAGGAAATTCACGGCGTTAAATCACGCCCACAGCTGGGAAAAACTATTCAAGTGCGAAATTTGTGGAAAACACTTAAGCACGTCTTGGGCGTTGAACAACCATTTGGGTATAGTTCATGGGAAAAATATCTCCGAAGGGCCTTTACTCAAACACCAGTGCAGAATATGCCTTAAGTCTTATTTGTATGAAAGTGGACTGAAACTGCATTATTCCAGTCAACACAAAGAATTAGGTATCGATTTCTCCGTAATATGCGACGTGTGCGGAAAAAGCCTCAGCTGCAAAAGTAAACTCAAGCAACACTTAAGGACCCACTCTGGAGATAAACCGTTTCCATGTCCCGTTTGTTCCAGAAAATTCATCACCAAAGACCTTATGACCTCACATATGCGAGTCCATACCGGGGAAAAACCGTACGTTTGTATGTACTGCGGCAAAGAATTCGCTCAGGGCGCCCCCTATCGGTACCACCTCAAAACGCACACCGGGGAGAAATGTTGCAGTTGCCATATTTGCGGCAAGGAGTTTATATCTAAAGGAAATATGAGGATACATTTGAAGAGTTGCAATATGAAAAAGGAGACGTTAATAAAGAACAACATAAAGAAATTTCGACGGAAATACATGAAGAAAAACAACCCGAACGTAATAAACTTGGACGACTTGGCCAAACCTTTAAAATGTCCGATTTGCAACGAAGTATTTTCCACAAATCGAGAATACGCCTACCATTCCTCGAGCCATAACGACGACAACAAATATTCCTGCCATTTTTGCGAATTCAAAACCGAAGAAAAGAAGCGAATGAAAACGCACATGATGAACCACTGTGTGTATAAGTGCGCCGTGTGCGAGAAAATTTTTCGAAAGAGACATTCGGCTTACAAGCACGCCGAAAGGCACATGGACCAAAATAGAGTGCAGTGTGAAATTTGCGGAAAGAGTTTGCAAAGCCAATCTTTAAAAACGCACATGAAGATAGTACACACCGACgaacttgaaaataataagCACAATTGTCCGTTATGCAACAAAACCTACAGATACGCTTCGAGTGTCAGAAAACACATTTCCTCCAATCACAGGGAATTAGGCATAGACGTGTCCGTAGTGTGCGACATTTGCGGCAAAAGGATATCGAGTAGGagcaaattaaataaacacaTTAGCATTCACACCGGTGATAAACCTCATTCTTGTGAAATATGTCACAAAAAATTCAGAGCGATCGATACGCTGAAATCCCATATGGTAGTCCACACGGGAGAAAAACCCTACAAATGCATGTATTGCGGAAAAGGCTTCGGTCAGAGTGCCCCCTATCGGTACCATATTAAAACTCACACAGGCGAAAAAAATTACAGCTGCGCCATCTGCGGAAAAGGTTTTATTTCGAAGGCAAATTGGAAatttactaATCTCAAACAATTTGCTACTGAATTCAAACTAGCACCGGATGATAAAAACAAGTCGAAATGTTCTGTATTTGATGAAACCCTTTTTAAAGAGTACATATTTAACGCCGCTGAAGCTGTTGCGCCTCTAGTATGTCTGGTTTGCAGATCGCACTTTAACACGAATCTAGACCTAGGACTGCATTCATCGACCCACAATCGAAATCGATACAGTTGCAATTTATGCGTTTTTGAAACTCGAAAGGAAAACGCGTTTCGTGGACACCTTACAAGGCACAATCAATTcgtttgtaaaaaatgtaacgttCAATTCAAATCCAAACAATCGGCTTTTAAGCATATCAAATTACACGAGTTTCCTAAGCTCAAGAAATGTCGGTTTTGCGGCAAAGAAATGTCGAAACATCTGCTTAGACAACACAAAATCGCCGAACATGAAGGAAACTCCCCGGGAACCGTCAAATGTTCGGTTTGTTCTAAAGAGTACCGTGATAAAGACAGTTTACAAAGGCATTACGCTTCGCAGCACAAAGAGTTCGGCGTGGACATCATTAAAATTTGCGAACTCTGCGGAAAAGAGTGTCCCAATAATCAACTGTTGAGACGGCATCGGAAAACGCATTTCGGAGAAAAACGGTACTCGTGTGCGCAATGCCCCAAAATGTTCTCTTTCAAAATGTCGCTGAATTATCACATGACCAAACACGCTGGAGTTAAACAATTCACTTGCAAATTTTGCGATAAGTCTTACAGGTACAAAAGTGGGTTGGAGTACCATTTGAAGACTCATTCCGGAATCCAAGAATACTCTTGTCCTctttgttcaaaattattcacTTCTAAGAGTAATATGAAAGTGCACTTAAAAGTTTGTAATGGTTTTAGTAAGTAG
Protein Sequence: MNRITARHPQLIAQPVELEVPLECKRCNKEFNNNIDFAFHSKEHDSEGKYTCHICDYTNISKPPFDLHMREHEGIHKYKCPMCPKTFKQSKDAAEHKYFHTGEKPFQCEICGKHFPYTKSLAAHRRNTHYEIITGKPLQKYDCKVCNRHYESHSGLVRHYSSSHKELGYDYSVVCDICGKTIATRNKLKYHLRVHTGYKPHECNVCHKGFSKKQELKIHERVHTGEKPFTCSYCGKKFAQLAPYRNRKKQKNTKTTKSTNKIPEPEIDEKLTKLSSILKIEKPLLCSSCQKAFNSHLELAYHSKKHNESKMHTCHLCNFTVATKFRIRRHINGHAGWKCQMCNKVFRKARAALKHWYMHTGEKMYGCEICGKHLANAKSLDTHLNTIHHEIITGKPLVKFDCPICKKHYESETGLRRHYSSSHREMGVDLTVICEVCGKRISNRTRLTRHMRTHNGEKPFPCSICERNFATKCLLTSHMRVHTGEKPYICSFCGKRFGQSAPYRYHIKIHTGDRRYVTTKRKYIKSKRQKNYRFIKEKENKIKNLLVMNEPMQCPVCKQSFQNLLDYAFHSKSHETNGFYSCHVCGKKVTHKKQFERHILSHKSFKCEVCNRVFKRKFTALNHAHSWEKLFKCEICGKHLSTSWALNNHLGIVHGKNISEGPLLKHQCRICLKSYLYESGLKLHYSSQHKELGIDFSVICDVCGKSLSCKSKLKQHLRTHSGDKPFPCPVCSRKFITKDLMTSHMRVHTGEKPYVCMYCGKEFAQGAPYRYHLKTHTGEKCCSCHICGKEFISKGNMRIHLKSCNMKKETLIKNNIKKFRRKYMKKNNPNVINLDDLAKPLKCPICNEVFSTNREYAYHSSSHNDDNKYSCHFCEFKTEEKKRMKTHMMNHCVYKCAVCEKIFRKRHSAYKHAERHMDQNRVQCEICGKSLQSQSLKTHMKIVHTDELENNKHNCPLCNKTYRYASSVRKHISSNHRELGIDVSVVCDICGKRISSRSKLNKHISIHTGDKPHSCEICHKKFRAIDTLKSHMVVHTGEKPYKCMYCGKGFGQSAPYRYHIKTHTGEKNYSCAICGKGFISKANWKFTNLKQFATEFKLAPDDKNKSKCSVFDETLFKEYIFNAAEAVAPLVCLVCRSHFNTNLDLGLHSSTHNRNRYSCNLCVFETRKENAFRGHLTRHNQFVCKKCNVQFKSKQSAFKHIKLHEFPKLKKCRFCGKEMSKHLLRQHKIAEHEGNSPGTVKCSVCSKEYRDKDSLQRHYASQHKEFGVDIIKICELCGKECPNNQLLRRHRKTHFGEKRYSCAQCPKMFSFKMSLNYHMTKHAGVKQFTCKFCDKSYRYKSGLEYHLKTHSGIQEYSCPLCSKLFTSKSNMKVHLKVCNGFSK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -