Basic Information

Insect: Hemicrepidius niger
Gene Symbol: topi
Assembly: GCA_963082805.1
Location: OY720160.1:40937579-40940457[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0011 0.11 14.1 2.1 2 21 132 151 131 152 0.94

2 14 5.2e-06 0.00052 21.4 1.1 1 23 177 199 177 199 0.97

3 14 0.011 1.1 11.0 2.0 2 23 206 227 206 227 0.95

4 14 0.028 2.8 9.7 0.2 2 19 246 263 245 265 0.94

5 14 2.4e-05 0.0024 19.3 0.7 2 23 337 358 336 358 0.97

6 14 0.25 25 6.7 0.1 1 21 364 384 364 385 0.92

7 14 0.14 14 7.5 2.3 2 19 401 418 400 424 0.83

8 14 0.31 31 6.4 0.1 1 23 538 561 538 561 0.96

9 14 0.006 0.6 11.8 0.1 1 23 565 587 565 587 0.97

10 14 9.1e-07 9.1e-05 23.8 2.4 1 23 593 615 593 615 0.98

11 14 0.032 3.2 9.5 0.2 1 23 621 646 621 646 0.96

12 14 0.55 54 5.6 2.5 1 23 652 674 652 674 0.85

13 14 2.6e-05 0.0026 19.2 0.3 3 23 682 702 680 702 0.98

14 14 4e-06 0.0004 21.8 0.5 1 23 708 731 708 731 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0011	0.11	14.1	2.1	2	21	132	151	131	152	0.94
2	14	5.2e-06	0.00052	21.4	1.1	1	23	177	199	177	199	0.97
3	14	0.011	1.1	11.0	2.0	2	23	206	227	206	227	0.95
4	14	0.028	2.8	9.7	0.2	2	19	246	263	245	265	0.94
5	14	2.4e-05	0.0024	19.3	0.7	2	23	337	358	336	358	0.97
6	14	0.25	25	6.7	0.1	1	21	364	384	364	385	0.92
7	14	0.14	14	7.5	2.3	2	19	401	418	400	424	0.83
8	14	0.31	31	6.4	0.1	1	23	538	561	538	561	0.96
9	14	0.006	0.6	11.8	0.1	1	23	565	587	565	587	0.97
10	14	9.1e-07	9.1e-05	23.8	2.4	1	23	593	615	593	615	0.98
11	14	0.032	3.2	9.5	0.2	1	23	621	646	621	646	0.96
12	14	0.55	54	5.6	2.5	1	23	652	674	652	674	0.85
13	14	2.6e-05	0.0026	19.2	0.3	3	23	682	702	680	702	0.98
14	14	4e-06	0.0004	21.8	0.5	1	23	708	731	708	731	0.98

Sequence Information

Coding Sequence: ATGAACAACTCGAATAATATATTCCTCACCGTACATCAAATCGCAGAAGATGGATCTGTAAGTTCGTATCAGTATGAAGAAGATTTCATTACCCAAGAGATGGTATCGAAGACCCCCATTTCCAATGGGGATATAAATTTTAATCCCCAGTATACTTGGAATTATCCAAGTGATAATAAAGTTAATCTCAGCTACCGTTATTTAGAACCTGACGATCAATCCATAACGATTGTTAAAATTGGGGGAGTAGAAGACTTAAACCCCATGAATTATGCTacggaaataagtacagtatTGAGTGATCCTGGTGATTGTAAACCTTATCTTATTAATAACAATGACAAAATAAATAAGCAGCGAGAGTCGAAAATTCCTAATATTCCGACTATGGTTCGTTGCCAGAATTGTGATACAAATTTTCCAACAAAATACCAATATCAACGCCATCAGTGTGAGTTCAACGCAGACAAAGTGgTTTTAAAACCGGATGCGGACATCAAAGACATTGATAAAGGTATGCGAATTAAATACGACTGCATGACTTGCGGTAAGCAATTTGTAAGCAAAAATAACTTGGAAAGACATCAGTCGAGCCATGATAACACCCAAGAAAATGTATGTGAGCATTGCAATAAACAATTTGTAAGTGAAAATCGACTCCGTATCCACAAAGAAAATCATTGCAAGAAAGCAGGTGATATTTCTAAGTTTTATCGCAGCGATGTAACTGTTTGGAAATGTCTAAAGTGTCACCAAGTATTTGCAACACCTACTTCAGCAAATAGACATGCGGAGGACTGTACAGAAATTTCAGTAATTCCCATTGATATCAAAACTGAAGATCCTGGGAGTTCTTCACAAGATTGCAGTGCATTAATGATGTTAcgagaagaaattaaaaatgtatcctcTTGTATTGCTCCAGAAATTGTCCAAGAGGAAGCTGGGACATCCGATAATGTTACTGGGTCTTCGAATGTAGAAAAAGTCCTTACcgaattattattacaatgtgAATATTGCAATCGTACTTATTCAGATCGAATCCTTTTGTTAGCCCATcaaaaaaaacatacaactaACAAGAATTATGAATGTGTAACGTGTAACGAAATTTTTGATTCATTCACTTCAGCAACAAAACATTGGCTAACACAATGTTCAGATgaagcaaatttattttacttacccAAAATGACTTACTGCGAGTACTGTGACCGAACATTTAAATCGCACGAAATTCTTTACACGCATAAAGTCAAAAAGAAGCATTACACACCTAAACTGCATGTTACAAGAGATATTGAAATCCAAAAAAGCATAGAAAGCAAAGAggttttagtaaaatttattgaaaatgcTCTTAGTACCATGATCGACAAAAACAAGGACAAGGAAAATATTAATGAAGATgcaaatgataaaaaaaatgaaaatccaATGGAGAATAGCAAAGAAATGAATGTAAAAGAGGAATTGAAAATGGAAGGAATGAGTCAAGATGGAGAACCTCAAGAACcggaaaaaaagaaaagaggTCGGAAACGTAAATGGCCTAAACAGATTACAAAATCTAAACGTGTTTCACTTATTATCGATGAAGGCTTCAAGTATCAATGTGAACGTTGTATTATGACTTTTGATAATATACCAGACCTAGAAATGCACCGAGAAAAAGAACATGCATCTAGTTTTTCCTGTGAAGAATGTGGACAGGTGGTTCACAGTGCTAAAGCGTTAATTATTCACAGCAGAGCTCATCAAAGTTTAAAACCGTATGTTTGTGAACAATGTGGTCGAAGTTATTCCCAAACTTCTCATTTATGGCAACATATGCGTTTCCATCAAgGTATAAAACCATTTGCGTGTCCCCATGAAGGATGTGAGGCTCGTTATACAATTCGACCAGATTTGAAGGATCACATCAGGAAAGTCCATACCCGTGAAAGACCTTTTAAATGTGCTGTCTGTAACAAGTGTTTCCTGACTGGTTCTGTTTACTACCAGCATAGACTTATTCATACAAATGATCGCAGATACGGATGTGATATTTGTGAAAAGAGATTTTTCCGTGCAGATGCATTGAATAATCATCGGAGGATTCATACTGATGAGAGACCTTATCCTTGTGAAATTTGTGGAAGAGAATTCAGGCAGAAAGGTGATAGGAATAAACATGTACGAACACAGCATCCAGAATAA
Protein Sequence: MNNSNNIFLTVHQIAEDGSVSSYQYEEDFITQEMVSKTPISNGDINFNPQYTWNYPSDNKVNLSYRYLEPDDQSITIVKIGGVEDLNPMNYATEISTVLSDPGDCKPYLINNNDKINKQRESKIPNIPTMVRCQNCDTNFPTKYQYQRHQCEFNADKVVLKPDADIKDIDKGMRIKYDCMTCGKQFVSKNNLERHQSSHDNTQENVCEHCNKQFVSENRLRIHKENHCKKAGDISKFYRSDVTVWKCLKCHQVFATPTSANRHAEDCTEISVIPIDIKTEDPGSSSQDCSALMMLREEIKNVSSCIAPEIVQEEAGTSDNVTGSSNVEKVLTELLLQCEYCNRTYSDRILLLAHQKKHTTNKNYECVTCNEIFDSFTSATKHWLTQCSDEANLFYLPKMTYCEYCDRTFKSHEILYTHKVKKKHYTPKLHVTRDIEIQKSIESKEVLVKFIENALSTMIDKNKDKENINEDANDKKNENPMENSKEMNVKEELKMEGMSQDGEPQEPEKKKRGRKRKWPKQITKSKRVSLIIDEGFKYQCERCIMTFDNIPDLEMHREKEHASSFSCEECGQVVHSAKALIIHSRAHQSLKPYVCEQCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCAVCNKCFLTGSVYYQHRLIHTNDRRYGCDICEKRFFRADALNNHRRIHTDERPYPCEICGREFRQKGDRNKHVRTQHPE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00399816;
90% Identity: -
80% Identity: -