Hfuc001145.1
Basic Information
- Insect
- Hemaris fuciformis
- Gene Symbol
- ZEB2
- Assembly
- GCA_907164795.1
- Location
- OU015459.1:3359439-3368456[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.00083 0.069 14.2 0.2 1 23 260 282 260 282 0.98 2 9 0.14 12 7.2 2.6 2 23 287 308 286 308 0.97 3 9 4.4e-05 0.0037 18.2 8.7 1 23 338 361 338 361 0.95 4 9 7.2e-05 0.006 17.5 1.9 1 20 365 384 365 388 0.96 5 9 1.8 1.5e+02 3.7 0.1 6 22 401 417 397 421 0.87 6 9 0.00029 0.024 15.6 0.2 2 23 434 456 433 456 0.95 7 9 0.67 56 5.0 2.6 1 23 462 485 462 485 0.89 8 9 5e-05 0.0042 18.0 0.4 3 23 496 516 495 516 0.99 9 9 2.9e-05 0.0024 18.8 0.1 1 21 522 542 522 543 0.96
Sequence Information
- Coding Sequence
- ATGTGTGCGATGAAAACGAATGAATTTGAAAATATTAATAAGTATAATGTAAGATACTGTCACGGTTGTCTTAGTACCGACAGAGCGCTTTCAGTTTTAGATGATTTAGACGATATATATTTAAAAATATGTGTGGATCCTATAAAGATGCCAACTTCCCAAATACCCTTGTGCTGGGAGTGTATTGCTATGCTAAAAAAGGTGCAACTCTTCAAAATGAGGTTTGATGAAGCACAAAGGACACTAAATATGAATCTTAAGAATATTGACAAAAAAAAACTAGATAGTCTGTCATCATTGATAATAAGTACACAAAATCGAAAAATAGAAGTTACTCATAATGATTTAATGCCAGTTGAAGTCAAAAGAGAAATTGATGCTGATGTATCTGATAATGAGTCCGATTTCTTAGTAATTGATGAAGATAAACGAACAGAACATGTGAAAGAAGAAGCAAACTTTAAAGAAGAGAAAGAGAATATAAAAGAAGACAAAGCGGTAACAGTAAAAGAGGAAGTGGATAAAAAAAATTCGAGTGTAACAAAGAACCATGTGAGACGGAAGTATTTCAGATCATTTTACTTTTTGAAAAAATACGAATTGAGAAGGAAAGTCAGAATTGACTCAGAAGAGATAAACAGTTGGGTGGAGAAGGACAGAGAGAGTGGCGTGTTTCAGGGGTTTAAATATAAGTGTGTGAAATGTGTTTATGGATGGAATGATGAAGACAAATTTGCTGAGCATAATAAGAAATATCATAATGAGACCCCAGAACCGTATACGTGTGACTTGTGCGCATCAAGTCTTAGGTCCAAGTCGTCCCTACGCGCCCATATTAATGCCCACAGAACGTTACAGGAGTGCACAGTGTGTTTGTTCCGATGTTACTCAAAAAGTCTTATTTACGCCCACATGAAAAGACATAGGCGCGCGGTGAAATGCCTTATTTGTGGTGCTCCGATGAAAAATATGATGTGTTTCTACAAACACTACAATGATAAGCACAAAACATTCTTATGCGACCACTGTGGGAAATGCTGCAAGACGAAATACATGCTCGAAAAGCATATCAGGAGGTACCACTTCGGAAAGTACCCGTGCACAAACTGCCACATGTCGTTCAAGTCTGCGAAAACATTGAAGAGGCACATTTGGCTGAAACATCTGCCCAGTACAGCCGAGAACGCTTACTGCGCCCCCTGTAACTTGCAGTTCGAAACCACGGCTTTGTACCGTCGCCACGTGCAGACCAGCGTTGCTCATGCTGCTGAAAGACGGAGCAGGAATAAAAAGCAAGTACCGTGTCCAGAATGCAGCAATGTGTATTCCCGAAAATCGTACATGATGAATCATTACAGATATGTGCACGAAAAACAATGGAAATATTATTGCACACTGTGCGATCGCCCATTCCTAAACCGCACTCGGTATATGGAGCACACGAAATTTAAGCATGAAGGCGTTATAAGGGAGAAGGACAAACTGTGCAGTATATGCGGAAGGGGATTTGCGGCTACCAAAACGTTAATGAATCATATGAGAACGCATTCCGGCGAGAGGCCGTTTGAATGCACCAACTGCGGTACAGGGTTCAGTCGGAGGAACTCTCTGATCGCGCACGTGAGAGACTGCCAGGGACCAAATGAAAGCGAAGAGAATGGGCCTGCCACCAATGCGGAATAA
- Protein Sequence
- MCAMKTNEFENINKYNVRYCHGCLSTDRALSVLDDLDDIYLKICVDPIKMPTSQIPLCWECIAMLKKVQLFKMRFDEAQRTLNMNLKNIDKKKLDSLSSLIISTQNRKIEVTHNDLMPVEVKREIDADVSDNESDFLVIDEDKRTEHVKEEANFKEEKENIKEDKAVTVKEEVDKKNSSVTKNHVRRKYFRSFYFLKKYELRRKVRIDSEEINSWVEKDRESGVFQGFKYKCVKCVYGWNDEDKFAEHNKKYHNETPEPYTCDLCASSLRSKSSLRAHINAHRTLQECTVCLFRCYSKSLIYAHMKRHRRAVKCLICGAPMKNMMCFYKHYNDKHKTFLCDHCGKCCKTKYMLEKHIRRYHFGKYPCTNCHMSFKSAKTLKRHIWLKHLPSTAENAYCAPCNLQFETTALYRRHVQTSVAHAAERRSRNKKQVPCPECSNVYSRKSYMMNHYRYVHEKQWKYYCTLCDRPFLNRTRYMEHTKFKHEGVIREKDKLCSICGRGFAATKTLMNHMRTHSGERPFECTNCGTGFSRRNSLIAHVRDCQGPNESEENGPATNAE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -