Hfuc001147.1
Basic Information
- Insect
- Hemaris fuciformis
- Gene Symbol
- ZNF219
- Assembly
- GCA_907164795.1
- Location
- OU015459.1:3378397-3385204[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.027 2.3 9.4 1.6 1 23 252 275 252 275 0.91 2 11 5.5 4.5e+02 2.2 0.3 2 23 283 304 282 304 0.87 3 11 0.12 9.7 7.4 1.6 1 23 308 331 308 331 0.97 4 11 0.0058 0.48 11.5 1.9 1 23 335 358 335 358 0.97 5 11 5.5e-05 0.0046 17.9 2.0 2 23 362 384 361 384 0.96 6 11 0.0054 0.45 11.6 1.4 3 23 389 410 388 410 0.96 7 11 0.0059 0.49 11.5 0.3 2 21 424 443 423 444 0.93 8 11 3.3e-06 0.00028 21.7 0.2 2 23 457 479 456 479 0.95 9 11 0.0082 0.68 11.0 2.5 1 23 485 508 485 508 0.95 10 11 0.00017 0.014 16.4 0.6 3 23 519 539 518 539 0.98 11 11 4.5e-05 0.0037 18.2 5.3 1 23 545 568 545 568 0.98
Sequence Information
- Coding Sequence
- ATGGAGAAGGTGAAAGCGGAATTTGATAAAACCGCTGTGTGCCACGGTTGTTTGAGTGTCAATCGTAGCGTATCAACATTGGGCGAATATTATGAGACATTTTATTATGTTTTAGGCGAAGGAATTCTTGACCTTACCGATAGACCTGATGTAGTCCTATGTTGGGAATGCAAGGCCATATTGAGGAAATTTAAATCTTTTCAGAGCCAAATCAGGAATGCACGAGACATGCTCTCGGATGCTTACTTTCATTGGAAATTCCAAGAGGATGTATACTCCCTATCAACTCTTGGGACTGTTAAAAAAGACAATTATGATCTGGTACTTGATGGGGATTTCACAGACTCTTCAAACCTGTACATAGCCCAGTTAACCTATCCAGAAGTTAAACAGGAAGAGATACCAGTAAACCAGGAGGTACAGGATGGCGATGCGACTGACTTGGTCGCGAAAGACGAATGCTTCCAGGATTGTGACCAGGACGAAGATTCGGATAATGATAATGGCGAGCCCATGGCAAATACAGCTCCTGTACAGAGTATTAAAGAAGCTAGGAAGAAGAAAGAAGAAACGGAAAGAGTGAGACAGCAGTCAATAAGAATATACGCAAAATACGCGAATGTATCGAAAGTGGAGAAGATAAATATGGACGAATTATCAAAATATTACATTAAAGTGCACTTAAATGAGAAAGAGATGGAGGAGTTAATGGAGAAGAGAGACAGAAGAGAGTGCAGTTTTCACAAAATGCCGTTTCAATGTCTAGAATGCAACCTTGGTTATAAAAGGATAACGGATTTTAACAGGCATAATCAGTTCAATCATTGCATGTACGAAAAACCAGTCCGGTGTCTAGAATGCAACAAAAAGCAGCCGTCTCTGGCCAGGATGGAAAAGCACTGGGCGCGTCACACCAGGATGTTCCGATGCCTACAATGTTACGAACTGTGTAGGTCTTTGGGTGAAGTGAAAAAACACATAAACAGAGCTCACACATCCGTGTATACTTGTAAATCTTGCAACGTGCAGTTCAACACTCTTCGAGAATTCAGCGTGCACTACAGAAACGACCATCAACGGATGTATTGCGATCACTGTGGCAAAGCTTTCTTTAAGAAGAGATTGTTGGAGGGGCATATCAGACGGAACCACATGCCGGCATACTGCGTGGTTTGCAATCGCTCGTACCAACAGTACCACGTGTTGGAGAACCATTTACGGACGTACCACCCGCACCTGATGCGCGGTGCTGCCAACACAGAGGCGTCGTACTGCGTCGAGTGCGACAAACAGTACAGCAGTGTGTATAAATACAAGAGGCACATCCTGCAGTCCGCGAGGCATACGCCGCAGAAAAAGGTCAGGGTTCCATGTCCTGACTGCGGCAAAGTGTTCACTCGCACCACGTACATGAACAATCACTACAGGCTAGTTCACGTGAAGGACACCAAACATCAGTGCGAGCTATGCAGTAAGTTCTTCGCGACAGGCTACGCTATGCGGAAGCATAAACAATACGTCCACGAGAAGAAAATGATGCCCAAAGACAAGATATGTGACATCTGCGGACGAGGATTTAGTACAAACAGAATCCTGAGCAACCATCGTCGGACGCACACGGGAGAAAGGCCCTTCAAATGTCCCCATTGTGGGGCCTCATTCGTACAATGCACAGCTCTGCACACCCACCTAAAGACACAGCACAAAAATATGGAACCTATGGTCAACGGCTGA
- Protein Sequence
- MEKVKAEFDKTAVCHGCLSVNRSVSTLGEYYETFYYVLGEGILDLTDRPDVVLCWECKAILRKFKSFQSQIRNARDMLSDAYFHWKFQEDVYSLSTLGTVKKDNYDLVLDGDFTDSSNLYIAQLTYPEVKQEEIPVNQEVQDGDATDLVAKDECFQDCDQDEDSDNDNGEPMANTAPVQSIKEARKKKEETERVRQQSIRIYAKYANVSKVEKINMDELSKYYIKVHLNEKEMEELMEKRDRRECSFHKMPFQCLECNLGYKRITDFNRHNQFNHCMYEKPVRCLECNKKQPSLARMEKHWARHTRMFRCLQCYELCRSLGEVKKHINRAHTSVYTCKSCNVQFNTLREFSVHYRNDHQRMYCDHCGKAFFKKRLLEGHIRRNHMPAYCVVCNRSYQQYHVLENHLRTYHPHLMRGAANTEASYCVECDKQYSSVYKYKRHILQSARHTPQKKVRVPCPDCGKVFTRTTYMNNHYRLVHVKDTKHQCELCSKFFATGYAMRKHKQYVHEKKMMPKDKICDICGRGFSTNRILSNHRRTHTGERPFKCPHCGASFVQCTALHTHLKTQHKNMEPMVNG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00291038;
- 90% Identity
- iTF_00788001;
- 80% Identity
- -