Basic Information

Insect: Hemaris fuciformis
Gene Symbol: THAP3
Assembly: GCA_907164795.1
Location: OU015459.1:4534610-4556143[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0046 0.38 11.8 1.0 1 23 350 372 350 372 0.98

2 11 0.008 0.66 11.1 9.8 1 23 379 401 379 402 0.94

3 11 0.069 5.7 8.1 1.5 1 23 406 428 406 428 0.97

4 11 0.056 4.6 8.4 1.8 1 23 433 456 433 456 0.97

5 11 0.013 1.1 10.4 0.3 1 23 460 483 460 483 0.92

6 11 2.4 2e+02 3.3 0.4 3 21 497 515 496 520 0.87

7 11 1.3 1.1e+02 4.1 0.4 2 23 575 597 574 597 0.94

8 11 0.0084 0.7 11.0 0.7 2 20 613 631 612 634 0.91

9 11 5.8e-05 0.0048 17.8 1.6 1 23 640 662 640 662 0.99

10 11 1.3e-05 0.0011 19.9 3.3 1 23 669 691 669 691 0.97

11 11 3.3e-05 0.0027 18.6 1.3 1 23 697 720 697 720 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0046	0.38	11.8	1.0	1	23	350	372	350	372	0.98
2	11	0.008	0.66	11.1	9.8	1	23	379	401	379	402	0.94
3	11	0.069	5.7	8.1	1.5	1	23	406	428	406	428	0.97
4	11	0.056	4.6	8.4	1.8	1	23	433	456	433	456	0.97
5	11	0.013	1.1	10.4	0.3	1	23	460	483	460	483	0.92
6	11	2.4	2e+02	3.3	0.4	3	21	497	515	496	520	0.87
7	11	1.3	1.1e+02	4.1	0.4	2	23	575	597	574	597	0.94
8	11	0.0084	0.7	11.0	0.7	2	20	613	631	612	634	0.91
9	11	5.8e-05	0.0048	17.8	1.6	1	23	640	662	640	662	0.99
10	11	1.3e-05	0.0011	19.9	3.3	1	23	669	691	669	691	0.97
11	11	3.3e-05	0.0027	18.6	1.3	1	23	697	720	697	720	0.95

Sequence Information

Coding Sequence: ATGAGGTGCTGTGTCTCTGGATGTAAGAATGATTCAAGACATATTTCTAAATCTCAAGGGATTACATTTCACGTGTTTCCCAACGAAGCTACTCTACGCTCGTCATGGCTCCGAGCCCTCGGCAAGGTAGACTGGGAGCCAAAAGACCGGAGTGCAGTCTGCTCAGAGCATTTCCTCTGCGAAGACCTTTATGAGACCAAAAGCGGCCTGAGGAAAGTCAAAGTTGGTGCTGTGCCTTTTATATTACAGGATCCAAGCAACAGTGATTATGGAAAAACTGCTAGCTTAAAAGTATGCCGCGTGTGTCTTGTAATGGACTGCAAAATGTTTCCGATCAGCGTTTACAATCTGAAACAGGCTTACGAACATCTAACTGGAATTACGATACGCGCAGAAGAGAATCTACCTCAAAAGTTATGTTACGAATGTGCAGCGCGGCTTCTAAACAGTTACAAATTCCGATCGAAATGTCTTCGAGCCAATTCACTTATGTTGGAACTCGTCAAGAAACAGAGAACGTTAAACCAACAAAATATAAAAAGTATTAGCAGAGAAAACAGCCAACTATCGTCAACACTTATTCAAAAGCACTTAACTGATCATTATGACTATAAAATAGACTACGAAGAACCCAAAGTGGAAGAAGTGAAAGAGATAAAAACAGAAGAAGTTGACTATGAGATATTTATCACGGAAAATGAAGAGATGGAGAAAATAGAAGAAACAGAAAGACCAGAAGACATTGAGAGATCTGCGTTAGATGTTACAGATGATGTATCAGAGAAGAATTATTCCTCAGATGACAGCATACCGCTGGAGAAGACAAGGAAAAGGAAAAAGGGAAAGATTGAGAAGAAGCAAGTCGTAAAAGTTCGGAAGAAACAGATAAAACGCGACCCAACCGAGCCGAAGATCGACCGCCGCCGCAAGCCGTTCCTCAACGACGATCTCAACGAGACCCTGTTCACGATCGCCGACCTCACGTACGAGGAGCAGGTGGCGGAGATCGAGAAGAGGCAGGACAGCGCCAACTACAAGAACGCCGTGTTCAAATGCACCGAGTGCTACAAGGGGTTCTTGGACGAGGACGCTTACAATACGCACATGACGAGGCACACGAACCAATGCGGCGACCACTCGTGCTCGATATGCAAGACGCACTTCAAGCACCCGCACGCGCTGCGGAAGCACATCACGGCGCACCACACGCAGCGGTTCAGCTGCAACCTGTGCCCGTACGTCACCACGCACAGACAGACGGCGAGGCTGCACGAACGGTGGCACAAGGGCACCAAATACCAGTGTCCACACTGTCAGGATGAGTTTGTTAAATTCACAACATACATGGGACATATAAGGATAAAGCACCCTTCTGACTTTGTGTGTGAGTTGTGCGGTTACTCGTTCGTGAGTATGAAAGGAATTGAACTGCACAAGAAGCTGAAACATAGGTTAGAAGATGGACAGATACCGGAAGATGGGCCTTTCTGCGAGCTCTGTAATGTAAGATTCGTCTCATTAGAGGCCCACAGAAGGCATCTACTCGTCTCGGCGAGGCATACAGATACCGATGCGGACGGGCGGGAGGCGAACAAGCCCAAAAAAGGTAGGAAGTCAAAAGAAACGAAAGAGAGGGAGAAGAGGGCCAGAGAGAAGAACAGAGAACCAGAGGAGAAGAGGAGAGTGTACCCTAGTCAATTGAGGAAGGCCGAAGGACCTATACCTTGTGAACAATGTGGGCTGCAGTTGGAAGATTCTCGCGCGTACCACGGCCACTTCAGGAGGATGCACCCGGACAAGAACCGAACCAAGTACCCCTCGATGAAGTCGCCTTGCATGTGCGAGGTTTGTGGCAGAATGTTCCAGAGTTATGCCCTGCTAAAAGACCACCGCTGGGTGCACACAGGGGAAAGACCGTTCAAATGTGACTCTTGCGACAAGTCCTTCCGCATGAAGCAGCGTTTAGTCGCACATCGCCGCATCCACAGCCAGATGAAGGCGGCGTACGCGTGCACACTCTGCGGGAAGAACTTCTCGACGCACAGCAACAGGCAGCGGCACATGTTTATACACACAGGTCTGAAGCCTTTCAAGTGTGAAATGTGTGGTAAAGGATTCAAACATGCAAGCGAAAAGCGAGCTCACATAACATATGTCCATCTGAAGAAACCTTGGCCTAAGAGGACTAGAGGGAAGAGGAGGAGTGATAGTAGACAGGGTATGCCGTCACAGCAGCCGACAAGTGGAGGTGAGCTGGACCCCGTCCAACCAATATGGCCGCCGTGCGACCCCAAAATGGCCGACATCAACATGATAGAAGACAAGCCAATGTATTACACTTTGAAAATATAG
Protein Sequence: MRCCVSGCKNDSRHISKSQGITFHVFPNEATLRSSWLRALGKVDWEPKDRSAVCSEHFLCEDLYETKSGLRKVKVGAVPFILQDPSNSDYGKTASLKVCRVCLVMDCKMFPISVYNLKQAYEHLTGITIRAEENLPQKLCYECAARLLNSYKFRSKCLRANSLMLELVKKQRTLNQQNIKSISRENSQLSSTLIQKHLTDHYDYKIDYEEPKVEEVKEIKTEEVDYEIFITENEEMEKIEETERPEDIERSALDVTDDVSEKNYSSDDSIPLEKTRKRKKGKIEKKQVVKVRKKQIKRDPTEPKIDRRRKPFLNDDLNETLFTIADLTYEEQVAEIEKRQDSANYKNAVFKCTECYKGFLDEDAYNTHMTRHTNQCGDHSCSICKTHFKHPHALRKHITAHHTQRFSCNLCPYVTTHRQTARLHERWHKGTKYQCPHCQDEFVKFTTYMGHIRIKHPSDFVCELCGYSFVSMKGIELHKKLKHRLEDGQIPEDGPFCELCNVRFVSLEAHRRHLLVSARHTDTDADGREANKPKKGRKSKETKEREKRAREKNREPEEKRRVYPSQLRKAEGPIPCEQCGLQLEDSRAYHGHFRRMHPDKNRTKYPSMKSPCMCEVCGRMFQSYALLKDHRWVHTGERPFKCDSCDKSFRMKQRLVAHRRIHSQMKAAYACTLCGKNFSTHSNRQRHMFIHTGLKPFKCEMCGKGFKHASEKRAHITYVHLKKPWPKRTRGKRRSDSRQGMPSQQPTSGGELDPVQPIWPPCDPKMADINMIEDKPMYYTLKI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00429076;
90% Identity: iTF_00290779;
80% Identity: iTF_00787721;