Basic Information

Insect: Hemaris fuciformis
Gene Symbol: ZEB2
Assembly: GCA_907164795.1
Location: OU015443.1:2060226-2071339[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 4.2 3.5e+02 2.5 0.3 2 23 7 28 6 28 0.95

2 13 0.0025 0.2 12.7 0.1 1 23 993 1016 993 1016 0.94

3 13 2.5e-05 0.0021 19.0 1.6 2 23 1115 1136 1114 1136 0.97

4 13 3.1e-05 0.0026 18.7 1.1 1 23 1142 1164 1142 1164 0.99

5 13 0.0096 0.8 10.8 3.0 2 23 1171 1192 1170 1193 0.94

6 13 0.13 11 7.3 0.8 5 23 1206 1224 1205 1224 0.96

7 13 0.019 1.5 9.9 1.1 3 23 1231 1252 1230 1252 0.96

8 13 0.0025 0.21 12.7 0.1 2 23 1269 1289 1268 1289 0.97

9 13 0.0031 0.26 12.4 0.5 1 20 1295 1314 1295 1317 0.89

10 13 0.0016 0.14 13.2 1.5 1 23 1325 1347 1325 1347 0.98

11 13 0.0062 0.51 11.4 7.0 1 23 1353 1375 1353 1375 0.98

12 13 6.2e-06 0.00052 20.9 1.4 1 23 1381 1405 1381 1405 0.98

13 13 0.001 0.083 13.9 4.2 1 23 1411 1433 1411 1434 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	4.2	3.5e+02	2.5	0.3	2	23	7	28	6	28	0.95
2	13	0.0025	0.2	12.7	0.1	1	23	993	1016	993	1016	0.94
3	13	2.5e-05	0.0021	19.0	1.6	2	23	1115	1136	1114	1136	0.97
4	13	3.1e-05	0.0026	18.7	1.1	1	23	1142	1164	1142	1164	0.99
5	13	0.0096	0.8	10.8	3.0	2	23	1171	1192	1170	1193	0.94
6	13	0.13	11	7.3	0.8	5	23	1206	1224	1205	1224	0.96
7	13	0.019	1.5	9.9	1.1	3	23	1231	1252	1230	1252	0.96
8	13	0.0025	0.21	12.7	0.1	2	23	1269	1289	1268	1289	0.97
9	13	0.0031	0.26	12.4	0.5	1	20	1295	1314	1295	1317	0.89
10	13	0.0016	0.14	13.2	1.5	1	23	1325	1347	1325	1347	0.98
11	13	0.0062	0.51	11.4	7.0	1	23	1353	1375	1353	1375	0.98
12	13	6.2e-06	0.00052	20.9	1.4	1	23	1381	1405	1381	1405	0.98
13	13	0.001	0.083	13.9	4.2	1	23	1411	1433	1411	1434	0.95

Sequence Information

Coding Sequence: ATGGAACACTTGCAGGTGCAATGCCCCGTGTGTACTCTGTACTTACACAATGGGATGACGCTGGAATCTCACCTCGACACTCACCCCAAAGACCAGGTTATCAAAGCTTTGTGCAGCCTTACCACAAAAGGCAGCAGCTTTGGAAGCAGAACACCTACACCACTGCATTCGGAACGGTCGTATAGAAGCAGGTCTCGCACACCTGTTACTGATGAAAGATGGAATAGTTCACAACAAAGTGCTGAACATGATAGGTACTGGCGGAGACCACCCAGCAGGACTGCTAAGTCTACAGTGACTAGTGTTTCAGGATGTAATACTCCAGAAACTGGTACAGGGGAGCATTTTGAAAGTAGTTCTGTAGCCTCGGGCCAGCATTCTTTGCCTCCTTATAGTGTGAAAAGTGATAAAGCTCAGCAAACATATCAGGTTTCTCCAATATCAGACTATGATAGCTTCTATCAGGATCAGCAAGAGGACAGAGAGATCAAATATTCTCGCAGTGCGGAATATACAGCAATGGACAATAGCAGTAGTGTCTTTAGTTATAACATGCCACCTATTGCGGGTGGCATGAGGTTCCAAGCAAATACCAGTTTGTTGCCAAGTATGTCAAAGAAAGCACCAGGATTTGTTAAAATTCTACCAAAACCAAACAATATCCTTGTAAAAACTAACCTAGGTGGTGTACAGTACATAGCTTCTGGAGTGAAACCACTGCATGTCATGATGCCTCCAGCACCTGCATTTGTACAGAAGAATATGCACAACAGCATGATCATGACAAGCAGTAATCACTCCTCACTGAATGTGGACAAAACAATAACCTCCCAATTAAGTGGCAACCATTTTAATCAGTTGACATCTGGAAATTTCTCCTCAGGGGTGTCGACAGTGATGACCCAAAATTCACATATTATATACAGAGAAATGGTACACAATATTGATGGAAAACCTTTCATTCCTAATGTACCCGGAGTTATGTCTACTGGTGCTAATGCCAACTTGGCTCAAACTAATCCTTTGTATCAAAATGTGATGGTTGTGGATCAGTTTGGTTCATGTATGTACACCAATCCACAGCAGCTTGTTCCTAAATCTTGTTCATCATCAATGTACACAGACACTGCATCCCTTGAACCAAGCAATCAACCTGTTAAGTCACCGGTAACTAACATAAATGATCCAAAGACATTAGTTATTGAAGTGAGCCCTATATTACCATCACAAAGTGTATCTCCATCCAGTACTGCTCCTAGTACCACAGTTAGCTTTTCAATACCACCAACACCTTCAACCACTCCTGAAACATCAGTTAAGATAGATAAAGCTGATGATAATATCAGTGTGAAATCTGATTCTAAGAGTGACTCGTTGGGTTCAAGTAAAGGCCTTAAAATTCTTAGCAATATAAAAGTTGAAGTGCCAGTTCAACATAATAAAAATATGGTGAATACTATCATGGACTTGACTGGAACAAATGATAATGATTATTTAGAAGTGGAAATAGAAAGTACAAAAGCACCAGAAATAGTCTTGCCTGATTTAAAAAATAAAGACAATGTTGAAAGCCCTTTAATACCTTCTAGTTCCAACAGTGATAAAAATTCATTTTCTGTGATAAAAAATGTTGGAATTTATACATCACATAGAGGCTCGTCCAGCAAATCATTAGAGAGTAAGTTAGATACTGAGTATAGTGATAACTGTCCTGTGCCTGATCTCATATGCAATGAGAAACCCTCAATATCACCATGTAGTGAATTATCTGAGAATGGTGAAAATTCTACTGATCACCATGCACTGTCCCCGAAACTCAAACAAGATAAGCAAAAGAAGAAGAAGTTAGAACCTGGAGAGATAAAACTTCAGGTAGCTGTAAAACCATATAGGCTAAACACATTAAGACTGAACAATCTGTATGTTAAAAAGAGCAAGAAAATTTTGCAAATAAAAAATGCAAAACTATTCCCAAAGAATATTTCAAGCAAAGTGGAACCTGAGCCAGTTCCATCCTCTAGCAAAGTGCCAGAAATTTATTCAATGAAAAAGCATATTGAGAAAGGTGAATTCAGAGAGCCTTCAACTTTACAAACTGTTTCTGTGGAAGAAATCAAAGACAATGATGATAACAATGGCTTTGATGCAGATATAGAGGAGCATTCTTTAGACATGGAGACATTGTCGGCGCCGCTCGTAATAAGCAATTCGACTGAGTTTTCCACCACTGTGGATATGGTGCAAGTGAAAGAGGAAACAAGTACCAGCAATGAAAGCGTATTTAACAATGAGGTCGAAACTCCTGGCGAGGTGCTTGGGCCGATTGAAAGTCTACGGCCCATTAACATGATGTATGGAAACCTTCCCGCAGATAATTACGACGAGGATGCAAATCACAAAGAATTGATAGGAATAGAAGCGACATCAAAAAATAAACAATTTATGAGCATGATGAACGAGAATTACTTCGGCGATCATATTTGTGCGAGTTATTTTTCTCAACAACGAGAGCAAACGCCTTTGCCAAAAGAAAGTGTGTACGGCGTGTGGGGTGAGCCTTCGCAGAAAGACAGTGCATTTGTGCTGCCGAACTTCATACATGACAAATACAAGTTACCTGAAAATAAGGGTATAGGTTATGCGGAGAGGGAAAGTAGGGAGGTTGCTGCGGATGTTGAAGGGGATGGATGTGAGAGGGACAGCAAAGCGGATGTTTTGAGTGAAGGCCGGAGCGAAGGTGATGCACCTCTCAACATTTGCGCGGACGAGCGTATGCCCCCGCGAGGAGAGCTCAGCGGGCAGGAGAGCAACGGAGACATGGAGTCAGCCTGGACCGGGATGTACACGGACGTGCCGCCTTCAGAGCCCTACGACCTGATGGCGCGCGAAAGTTGGGTCTCGGACGGGTCAGACGTCGACGTCGGCGAAAAGAGGGAGAATATAGAGGAAGAAATCCCGTACCCAAAGAGTCGGACGTACTCGTGCGCACTATGCAGCTTGAAGTTCCCGACGCCGAAGGAGTTGCGCGCGCACCGTGCGCAGGCGCACGCCGCCGCCGCCGGGAAGACCTCCTACAGCCGCATGATCACGGCGCGGGCTATCAAGAAGGAGGAGAAGACGGATGACAGCATGATGTCGTGCAATATGGTGGACACGAAAGAATCTATAACATCAACGATATTAGAAGTGTATGATATGGAGGAGACAAAGCTGTCGACGAAGATCGAAGGGATGATCAAGCAGGAGACCAAGAGGAGGCGGAAGGACTATGTGTGCCCCACGTGTAAAGTGGACCAGCTGACGGACGCCGCGTTTCATGCTCACCTCAAAATTCATCCACTTGAGTGCCTCACCTGTGGGAAATGTTTCTATAAAAGGGCAAATCTGGCTCTCCATATAAAAACTCATTTAGGTATTAAAAATTACAAGTGTGACGTGTGCGAGAAACGTTTCGTAACGCGCCAGAAGCTGTCGGAGCACCAGAACGTGCACACGGGCCGCGCGCCCATCAAGTGCACCATGTGCGACGACACCTTCCGCAGATACTCCAACATGGTGCAGCACAGGGACCGGCACCACTTCGGCAAGCGGGCGCGCGTGCGCGACTTCGTGTGCCAGTGCGGCGCCGTGTTCCACTCGCGCGCCAAGCTGCTGTGGCACCAGGAGACGCACGACGAGAGGCCCAAGGCGTGCCTCTACTGCAGCGACAAGTTCGTGCACGCCGCCTCCCTCACGCGCCACGTGCGCCGCACCCACAACCAGCACTACCTGGCGCCGCGCGCGCGCTCGGGCGCAGAAAACGTGCCCTGCCCCGTCTGCAAACAGGTGTACCTGAGGAGTAACCTGCGCACCCACATCCTGACGCACAGCGGGAAGCGCCCGTACGTGTGCATCGTGTGCAACAAGGGCTTCACCACCAAATGGAACCTGAAGCTACACCGTTGGACGCACATGAGCCGCTCGGCCAAGCCGTTCAAGTGCCATCTGTGTAAAGGTGCATTCATCCGTCAAACAGAGTACGTCACGCACATGAACGCGCACAAATCCGTCAAACCGTACACGTGTAACTACTGCGGCTGCCAGTTCGTTAGGAGATACAATTGCCAGAGGCACGTTAGAGAGCACGAGACTGTTAAGAAATACGTGTGTAAAGTGCCAGAGTGCGGGAAGTCTTTCCACAGGAGTTATTACTTGTCGGATCATATGAAGGTGCACAGTGGCGCGCGACCCTTTGCGTGTAATATCTGCGGTAAGACTTCTAGCAATAAGTCTAATCATAATAAGCACGTGAAGATCCATCATGCGCGGGAACCGGTGGCCACAGAAGCGTAG
Protein Sequence: MEHLQVQCPVCTLYLHNGMTLESHLDTHPKDQVIKALCSLTTKGSSFGSRTPTPLHSERSYRSRSRTPVTDERWNSSQQSAEHDRYWRRPPSRTAKSTVTSVSGCNTPETGTGEHFESSSVASGQHSLPPYSVKSDKAQQTYQVSPISDYDSFYQDQQEDREIKYSRSAEYTAMDNSSSVFSYNMPPIAGGMRFQANTSLLPSMSKKAPGFVKILPKPNNILVKTNLGGVQYIASGVKPLHVMMPPAPAFVQKNMHNSMIMTSSNHSSLNVDKTITSQLSGNHFNQLTSGNFSSGVSTVMTQNSHIIYREMVHNIDGKPFIPNVPGVMSTGANANLAQTNPLYQNVMVVDQFGSCMYTNPQQLVPKSCSSSMYTDTASLEPSNQPVKSPVTNINDPKTLVIEVSPILPSQSVSPSSTAPSTTVSFSIPPTPSTTPETSVKIDKADDNISVKSDSKSDSLGSSKGLKILSNIKVEVPVQHNKNMVNTIMDLTGTNDNDYLEVEIESTKAPEIVLPDLKNKDNVESPLIPSSSNSDKNSFSVIKNVGIYTSHRGSSSKSLESKLDTEYSDNCPVPDLICNEKPSISPCSELSENGENSTDHHALSPKLKQDKQKKKKLEPGEIKLQVAVKPYRLNTLRLNNLYVKKSKKILQIKNAKLFPKNISSKVEPEPVPSSSKVPEIYSMKKHIEKGEFREPSTLQTVSVEEIKDNDDNNGFDADIEEHSLDMETLSAPLVISNSTEFSTTVDMVQVKEETSTSNESVFNNEVETPGEVLGPIESLRPINMMYGNLPADNYDEDANHKELIGIEATSKNKQFMSMMNENYFGDHICASYFSQQREQTPLPKESVYGVWGEPSQKDSAFVLPNFIHDKYKLPENKGIGYAERESREVAADVEGDGCERDSKADVLSEGRSEGDAPLNICADERMPPRGELSGQESNGDMESAWTGMYTDVPPSEPYDLMARESWVSDGSDVDVGEKRENIEEEIPYPKSRTYSCALCSLKFPTPKELRAHRAQAHAAAAGKTSYSRMITARAIKKEEKTDDSMMSCNMVDTKESITSTILEVYDMEETKLSTKIEGMIKQETKRRRKDYVCPTCKVDQLTDAAFHAHLKIHPLECLTCGKCFYKRANLALHIKTHLGIKNYKCDVCEKRFVTRQKLSEHQNVHTGRAPIKCTMCDDTFRRYSNMVQHRDRHHFGKRARVRDFVCQCGAVFHSRAKLLWHQETHDERPKACLYCSDKFVHAASLTRHVRRTHNQHYLAPRARSGAENVPCPVCKQVYLRSNLRTHILTHSGKRPYVCIVCNKGFTTKWNLKLHRWTHMSRSAKPFKCHLCKGAFIRQTEYVTHMNAHKSVKPYTCNYCGCQFVRRYNCQRHVREHETVKKYVCKVPECGKSFHRSYYLSDHMKVHSGARPFACNICGKTSSNKSNHNKHVKIHHAREPVATEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01430180;
90% Identity: iTF_00290954;
80% Identity: -