Basic Information

Insect: Hemaris fuciformis
Gene Symbol: ZFX_1
Assembly: GCA_907164795.1
Location: OU015450.1:13637230-13643029[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 28 0.61 51 5.2 2.3 1 23 181 204 181 205 0.96

2 28 5.3 4.4e+02 2.2 2.2 1 23 251 273 251 273 0.95

3 28 7.4 6.1e+02 1.8 0.1 6 23 285 303 285 303 0.94

4 28 0.0023 0.19 12.8 0.2 2 23 312 334 312 334 0.94

5 28 1.6e-06 0.00014 22.7 1.0 2 23 357 378 357 378 0.97

6 28 4.9e-07 4.1e-05 24.3 0.5 1 23 385 408 385 408 0.97

7 28 0.0048 0.4 11.8 0.0 1 23 414 436 414 436 0.97

8 28 0.0001 0.0084 17.1 0.6 1 23 442 464 442 464 0.98

9 28 0.00013 0.011 16.7 7.2 1 23 470 492 470 492 0.98

10 28 0.88 73 4.7 5.1 1 23 607 629 607 629 0.95

11 28 0.0006 0.05 14.6 2.0 2 23 636 658 635 658 0.92

12 28 3e-06 0.00025 21.9 2.3 1 23 664 686 664 686 0.98

13 28 2.8e-06 0.00023 22.0 3.5 1 23 692 714 692 714 0.99

14 28 0.0048 0.39 11.8 2.7 1 23 720 742 720 742 0.96

15 28 3.2e-05 0.0027 18.6 3.3 1 23 748 770 748 770 0.95

16 28 0.075 6.3 8.0 0.1 1 17 776 792 776 792 0.92

17 28 0.099 8.2 7.6 1.4 2 23 838 858 838 858 0.97

18 28 1.7e-05 0.0014 19.5 0.0 1 23 864 887 864 887 0.95

19 28 3.2e-06 0.00027 21.8 4.3 1 23 893 915 893 915 0.97

20 28 0.0011 0.094 13.8 0.1 1 23 921 943 921 943 0.98

21 28 0.00015 0.013 16.5 0.1 1 23 948 970 948 970 0.97

22 28 0.028 2.3 9.4 0.2 5 23 979 997 976 997 0.95

23 28 0.00076 0.063 14.3 1.2 2 23 1158 1180 1158 1180 0.96

24 28 4.3e-05 0.0036 18.2 0.2 3 23 1188 1208 1187 1208 0.95

25 28 0.00019 0.016 16.2 1.1 1 23 1214 1236 1214 1236 0.98

26 28 0.0074 0.61 11.2 0.9 1 23 1242 1264 1242 1264 0.94

27 28 5.3e-05 0.0044 17.9 2.6 1 23 1270 1292 1270 1292 0.98

28 28 0.00012 0.01 16.8 0.4 1 23 1299 1322 1299 1322 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	28	0.61	51	5.2	2.3	1	23	181	204	181	205	0.96
2	28	5.3	4.4e+02	2.2	2.2	1	23	251	273	251	273	0.95
3	28	7.4	6.1e+02	1.8	0.1	6	23	285	303	285	303	0.94
4	28	0.0023	0.19	12.8	0.2	2	23	312	334	312	334	0.94
5	28	1.6e-06	0.00014	22.7	1.0	2	23	357	378	357	378	0.97
6	28	4.9e-07	4.1e-05	24.3	0.5	1	23	385	408	385	408	0.97
7	28	0.0048	0.4	11.8	0.0	1	23	414	436	414	436	0.97
8	28	0.0001	0.0084	17.1	0.6	1	23	442	464	442	464	0.98
9	28	0.00013	0.011	16.7	7.2	1	23	470	492	470	492	0.98
10	28	0.88	73	4.7	5.1	1	23	607	629	607	629	0.95
11	28	0.0006	0.05	14.6	2.0	2	23	636	658	635	658	0.92
12	28	3e-06	0.00025	21.9	2.3	1	23	664	686	664	686	0.98
13	28	2.8e-06	0.00023	22.0	3.5	1	23	692	714	692	714	0.99
14	28	0.0048	0.39	11.8	2.7	1	23	720	742	720	742	0.96
15	28	3.2e-05	0.0027	18.6	3.3	1	23	748	770	748	770	0.95
16	28	0.075	6.3	8.0	0.1	1	17	776	792	776	792	0.92
17	28	0.099	8.2	7.6	1.4	2	23	838	858	838	858	0.97
18	28	1.7e-05	0.0014	19.5	0.0	1	23	864	887	864	887	0.95
19	28	3.2e-06	0.00027	21.8	4.3	1	23	893	915	893	915	0.97
20	28	0.0011	0.094	13.8	0.1	1	23	921	943	921	943	0.98
21	28	0.00015	0.013	16.5	0.1	1	23	948	970	948	970	0.97
22	28	0.028	2.3	9.4	0.2	5	23	979	997	976	997	0.95
23	28	0.00076	0.063	14.3	1.2	2	23	1158	1180	1158	1180	0.96
24	28	4.3e-05	0.0036	18.2	0.2	3	23	1188	1208	1187	1208	0.95
25	28	0.00019	0.016	16.2	1.1	1	23	1214	1236	1214	1236	0.98
26	28	0.0074	0.61	11.2	0.9	1	23	1242	1264	1242	1264	0.94
27	28	5.3e-05	0.0044	17.9	2.6	1	23	1270	1292	1270	1292	0.98
28	28	0.00012	0.01	16.8	0.4	1	23	1299	1322	1299	1322	0.96

Sequence Information

Coding Sequence: ATGAATAGGAAAACAAAACAGCGATTCGTTATGAACGCAAATGATAATCAGCCTTCGTCAACAGCCCAGAGACTACTGGAAACGATTGCAGCGGCTCAAGTCAATCTCGAGAATGTGCAAGAATTTTCCAATGTGTGTCGAATATGTGCCACCGACACCGAGTTTGTTATACCAATATTTGAAGGTGAAGGGTTGCAGAACAACCTTGCAGAGAAGATACAGAAGTATTTACCCATAACGGTCACAGAACAGGATGTACTGCCCAGAGTGGTGTGCTACCAATGTGCTAGTACATTATTTGCATGGCATGAACTGGTCAATTGCTGCGTGCAGGCAGATGCCGCACTTAAATCCCGTTTGCCAAAACCACCTTCTGCTCAACAGGATGTAAAACCATCTGTATCCGGAACCAGCCAACCTGTCAACACAAACCAAAAAACCAAGTGTGACACTCCCATAGAATTTTATGATAAGGTTAGAATTGTTCTGACTGATTACTATCACACATTGAACATTGATGAAAATGAATCAGATATGAAATACGTATGCCAGAAATGTACTGCAAAATCACTGACTACTACAGCCATGTTGGCTGATCACCTACATACTCATCACTATGATGAAGTCTGCAAAAACCTTGAAATGTGTATCAAAGAGTTTATAACATTTGAAGAAACTTTAATGTCTGAAGCGTCAGATCGTGAAGAGCAATCTGATAAAGAAGAAATGCCTGATAAAGAAATACCCAATTACTTCTGCCCATTCTGTGAAAATATTTACTCATCTCCAACGCGACTGCTCTGCCATTTGAATAAACACGTGGAACTGAGCTTAGAAGACGGTGTCATGTGCTGCGAAGTCATTTACAAGGATAAAAACGCGTTCGTAACCCATTTGCAAAAGGACCATGTGGATCGTGTCGCTACGAACAACGTTTGCAAAACCTGCGGCTACAGTACAAATGATGTCAATGATTTACAAAAGCACATCAATGATCTACACGTATCTGACAACTCTGTAAAAGAAAAGACGTCGCAGAGCATTAGGAACCAAAAGTACATCCCAGCCGTTTGTCCGGAATGTAACAAGACATTCTCCAACAAATACAACATGTTTGTACATCTAAAAAGCCATAGCGAAAAGAGTGCGATGTATTCCTGTGATAAATGTAATAAAGTTTACACAAATCCAGGCAATCTGAAGAGCCACCAGCGTCTGGCACATGAAGGGATTCTCAAATATGTGTGTTCTGAGTGTGGAGAAGGTTTCCCAAGCCGTGCCAGTCGCGACGTACACGCCAGGATACACTCCGGAGTAAAACCTTTCCGATGTGATCAGTGCGGCAAAGCATACCGAGCCAAGAACACGCTGGACCGCCATTTAGAAACCCATTTAGACCTGAGGAAATACGAATGCCACATCTGCAACAAGAAATTTCGAAAACGAACACATTTAAACTATCACGTGAGCACGCACGCAAAGAAAAGTAACGGAAGTTGTTTAATCGACGACGATGACGAACCACTGTCAAATCTAGCGAACAAAAAAACAAACGATCTATATAACAATTTTTACAAAGCTTTAGTAAACTTCAAAAACCATTTCGCTACCAAACATAAATCTTTAGAAACGTACCCACAGCTCACTGATTCTAGTGACTCGGAGGCTTTAGATGATATCGAAGAAAGTAACGTAAATGGAGACAGCATTGAAAACTACGATGATCTCTCACAGTGCAATATGAGAAAAGATCGCATGGACGAGGAGTCTAGGCTAGAACTCGTACAAGTACAGAGAAAAGTCAATGGAAAAGTGTACTACACTTGCAAGATATGCGATAAAAATTTAAGTTCCACTCACACTTACTTCTTCCACAAGCGAATTCATACAGGAGAGCGTCCCTGCGTGTGTCACGTGTGCGGGAAGCAGTTCCGAGCACCCAATGGCTTGCAGAGACATCTGACGGAAACACACGAGCGCCTCCGAAGACATACATGCCTGCTGTGCCCTAAGAAATTCGCGAACTCTCAGAACCTCAAACAGCATATGAGAATCCACACTGGAGAGAGGCCTTACGTTTGCGTTCATTGCGGAAAGCGGTTCACCCAGAGCGGCTCTTTGCACGTCCATTTGAAGACCCATAGCGAACAATATCCTCATCATTGTGCTGAATGTGGAGCCAAATTCAGACTTCGAGCTGGACTCACTCGCCATAGGCTAAAACATACTGGTGAAAGACCCCACGCATGCGTACATTGCGGGAAAGGGTTTAGACAGAGGCACGAACTAAACAACCACATAATAATCCACACGGACGCGAAGCCCCACACTTGCGTTGTCTGCGGAACGGCCTTCAAGCAGCGACGAGCTTTGAGACCGACTAAAATATCGTCAGCAAATCAGTTAAACGAAGACGAAGCACGCGAAGTCACGAAAGCTGAACTAAAAATATTGATAGACAAACATCCTAGGCGTCTAGTGAGTGTCGGCGAGGACGGTAAGAAGTACGCCAAGTGCAAGTATTGCGATAAGAACATCATTCTAAGTTCTTGGAAGCGTCATATCAGACGTCACGAGGGCGAGAAACGCTACAGCTGTCCCACCTGCGGGCTCGGGTTCAACGATAACGGCAATCTGGCCAGACACGTGAAAGCCTTGCACAGTAAACAGCGACCTCACGTCTGCGAGCTTTGCAACAAATCGTTCTCACGAAACAGTCACTTGCAAGACCACGTCAAATCGCATTCAGAAAGTAGAGACTTCGTGTGCGACGTTTGTGGAAAAGCTTCAAAATCGGGTGCGGCGTTGAGAATGCACCGGAGCACTCACAAGGAGTGCCGGTTCGAGTGCATGCAGTGCGGCGCCAGGTTCAAGCGGCGCGGCGAGCTGGCGGCGCACGTGTCGGTGCACACGGGGGAGAGGGCGCACCGCTGCGGCTGCGGCAGGGCCTTCCGCCTGCCCGCGCAGCTCGCCGCCCACGCCAGGGCGCACCGCCACCGTGACCAACAACATCTTGCGACCAACCAACCACACCTCCCAGAACCTATGTTCGAGCCCCATATGGTTGACAAACACCCTGGAATGGTGTTCCTCTGCGAAGAATGTGACTCTTATATCGGTATGGAAAACTTCCTGGTCCACATGACCGACCACGACAAGGAGTACACCAACGCAGCAAGATTTGCGCAGGAACAAAGCCAGGAACCGAAGGTTGTTCAAAATAAAAATAAAAAAGACGAGAATGACAACACTGCCCCGGAAAGTGTTCCGGAGACCCCGCCCCAAGATAACACCTCTCCCCCCAACGATACCACTAATGCCAATGAAAGTTCAAGCGAGCTCGGACCTATACCTGAATCAGCGATCGAAATTGTAGATGATTCCTGCGACAACACCACTGCCGGGCAGTCAACTGACCAACCAGCGTCGAACGACGGGGCACAAACGCGATCAAAATCGAAGAAATCCCGGACTTGTCCCATCTGCTCGAAGAGTTACAGGGCGTCATCCAGCTATTTCTATCACATGAAGAACTTCCACGGCAAGAAACAGGAGCACGGGTGCGACATATGCGGCAAGAAGTTCGCATCCAAAGCGAATCTGACGCAGCACGGCTTCATCCATTCGAAGGAGTACCGGTACGAGTGCAAGACGTGCTCGAAGCGGTTCAAGGGCCGCGCCAACCTGTACATCCACGCGCAGAGCCACGCGGGCACGCCGCGGCACGCGTGCGCGCAGTGCGGGCGCGGCTTCCGCTGGCGCTCCTCCCTCACCAAGCACGAGGCGCGCCACGCGGCCCACAAGGCGCACCGCTGCGACGCGTGCGGCCGCGCCTTCAGTACGCGCTGCGACCTCGCGCGGCACGCACGCACGCACGCACGCACGCGCGCGCGCTTCCCGTGCGACTCGTGCGGCCGCAGCTACGCACAGCAGCGCTACCTCAACGCGCACGTCACCACCAAGCACTCCGCGCCACAGAACAAAAACAACAAAAAAACACGCACTACTTAA
Protein Sequence: MNRKTKQRFVMNANDNQPSSTAQRLLETIAAAQVNLENVQEFSNVCRICATDTEFVIPIFEGEGLQNNLAEKIQKYLPITVTEQDVLPRVVCYQCASTLFAWHELVNCCVQADAALKSRLPKPPSAQQDVKPSVSGTSQPVNTNQKTKCDTPIEFYDKVRIVLTDYYHTLNIDENESDMKYVCQKCTAKSLTTTAMLADHLHTHHYDEVCKNLEMCIKEFITFEETLMSEASDREEQSDKEEMPDKEIPNYFCPFCENIYSSPTRLLCHLNKHVELSLEDGVMCCEVIYKDKNAFVTHLQKDHVDRVATNNVCKTCGYSTNDVNDLQKHINDLHVSDNSVKEKTSQSIRNQKYIPAVCPECNKTFSNKYNMFVHLKSHSEKSAMYSCDKCNKVYTNPGNLKSHQRLAHEGILKYVCSECGEGFPSRASRDVHARIHSGVKPFRCDQCGKAYRAKNTLDRHLETHLDLRKYECHICNKKFRKRTHLNYHVSTHAKKSNGSCLIDDDDEPLSNLANKKTNDLYNNFYKALVNFKNHFATKHKSLETYPQLTDSSDSEALDDIEESNVNGDSIENYDDLSQCNMRKDRMDEESRLELVQVQRKVNGKVYYTCKICDKNLSSTHTYFFHKRIHTGERPCVCHVCGKQFRAPNGLQRHLTETHERLRRHTCLLCPKKFANSQNLKQHMRIHTGERPYVCVHCGKRFTQSGSLHVHLKTHSEQYPHHCAECGAKFRLRAGLTRHRLKHTGERPHACVHCGKGFRQRHELNNHIIIHTDAKPHTCVVCGTAFKQRRALRPTKISSANQLNEDEAREVTKAELKILIDKHPRRLVSVGEDGKKYAKCKYCDKNIILSSWKRHIRRHEGEKRYSCPTCGLGFNDNGNLARHVKALHSKQRPHVCELCNKSFSRNSHLQDHVKSHSESRDFVCDVCGKASKSGAALRMHRSTHKECRFECMQCGARFKRRGELAAHVSVHTGERAHRCGCGRAFRLPAQLAAHARAHRHRDQQHLATNQPHLPEPMFEPHMVDKHPGMVFLCEECDSYIGMENFLVHMTDHDKEYTNAARFAQEQSQEPKVVQNKNKKDENDNTAPESVPETPPQDNTSPPNDTTNANESSSELGPIPESAIEIVDDSCDNTTAGQSTDQPASNDGAQTRSKSKKSRTCPICSKSYRASSSYFYHMKNFHGKKQEHGCDICGKKFASKANLTQHGFIHSKEYRYECKTCSKRFKGRANLYIHAQSHAGTPRHACAQCGRGFRWRSSLTKHEARHAAHKAHRCDACGRAFSTRCDLARHARTHARTRARFPCDSCGRSYAQQRYLNAHVTTKHSAPQNKNNKKTRTT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -