Basic Information

Insect: Helleia helle
Gene Symbol: PLAGL2
Assembly: GCA_963853865.1
Location: OY971414.1:6625881-6627422[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 5.9e-06 0.00062 20.9 0.8 1 23 109 131 109 131 0.97

2 7 0.00016 0.017 16.4 1.4 1 23 137 159 137 159 0.96

3 7 4.2e-08 4.4e-06 27.7 2.0 1 23 165 187 165 187 0.97

4 7 0.035 3.7 9.1 0.8 1 23 194 218 194 218 0.92

5 7 0.00015 0.016 16.5 0.4 2 23 226 247 225 247 0.97

6 7 0.002 0.22 12.9 1.9 1 23 261 283 261 283 0.91

7 7 2.9e-05 0.003 18.8 2.4 1 23 289 312 289 312 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	5.9e-06	0.00062	20.9	0.8	1	23	109	131	109	131	0.97
2	7	0.00016	0.017	16.4	1.4	1	23	137	159	137	159	0.96
3	7	4.2e-08	4.4e-06	27.7	2.0	1	23	165	187	165	187	0.97
4	7	0.035	3.7	9.1	0.8	1	23	194	218	194	218	0.92
5	7	0.00015	0.016	16.5	0.4	2	23	226	247	225	247	0.97
6	7	0.002	0.22	12.9	1.9	1	23	261	283	261	283	0.91
7	7	2.9e-05	0.003	18.8	2.4	1	23	289	312	289	312	0.94

Sequence Information

Coding Sequence: ATGGCCAGCTCGCCACCGAACCCAAGAGAAGGCGAGGAGGGCGGCTCCGAGTTCACGGAGGAGACGAGCAGCCAAAGCGCGGCCTCCTCGCAGAAGATCTTCATAGCGCCATCCGCATCGCAACTACCTACGAAGCTAGAATTCGTGGCTCGCGGAGGTACTGGACGTAGCATTAAACACACGTTTCGTACCGTTAAAGTCGCTAGAAGAGTGCCCACACTGCCGCCAAAGAAAATTGAGGGTGCATCTGGCGGGGCAAGTGGATCGGGCGCGCCCAGCCAGGCAGCACCTGAACGCCGTCAGCGCCGCGACCGCTGCAAGCGACACGTTTGCACCATCTGTGATAAACGTTACTCCAGCCCGGGTAAGCTTAGTCAACATATACTCTCGCATACGGGTGAACTACCCTTTTCATGTGATCTATGTGAAAAGCGATTTAATTCTAAATTCAAGCTACTTCGCCATGGTCTTATTCATAGTGAAGCTAGAGCTTTTGCTTGTACAGTTTGTGGTAAAACTTTTAATCGTAAAGATCATCTCACAAATCATGTTAGAGTGCATAATCCGGTTAAAAAACTTCATACATGTGAGTGGCCAGGTTGTAGAAAATCTTATACATCTCTACTCAGCTACCGTAAACATGCCGCTTTACATTCTGCTGAGGAAGGTAACCTACAATGCAAGATCTGTGATCAAATGTTCACTTCTCAACAGGATATTGTATATCATCTCAAAGTACATACAGGTAGTCGTACTATTAAAACTGAAACTGACAAAAAATACCTTTGTGACCATTGTGACAGAAGATTTTTTACGGCCAAAGATGTTAGGAGACATTCAGTTGTACATACAGGAAGACGTGACTTTCTGTGTCCTCATTGCCCACAAAAATTTGGGAGGAAGGATCATTTAGTCAGACATGTTAAGAATGCCCATCCAGATGAATCATGGAGGTCTGCAGCTGTAGGTACTTCCAAAGACCCACCTTTAGAATCTACTACAATAAAAGAATGCTATACACAGTATCCTGTAGAAAGATCAGATTTTGATATTTGGAAATCATCATTTTCTAAGGAAGAATTAGAGGAAGGACAGACAAGTGTACCAGCATCAGATATTATCGTTGAAATGCCGCAAGATCTTGATATTAAGGTAGAGCCTCTTGAGGTAGAAGATTCTGTGGAAGTAAAATTAGAACAGCCAACATCACCGAGTTGTGAAATTATTGAATATCCAGTGATGTATATTGTGCCACCTGCATATACCCACACACCGTCTGACTTGCCGTACATTACTACACAGCCACTCTCAGACCAATTAGATGCACATTTACTTACTACAGAGAATGTTGAATCATTGCTGATAGACCCGGGAGAGGGGCCTTCTGGCCTCTCAAGCCAAATGTTAGGTTTACTGGAAGAAAGTGAACAGACTTATGTGAGTGAAGAGGTCCGTACACAACAAAGGCTACCAGCCTTTACGCAAGCCTTTCAAACTGCACAAAGTCCGAAACCACCACTGCCTCCCCCTCCACCACATTAG
Protein Sequence: MASSPPNPREGEEGGSEFTEETSSQSAASSQKIFIAPSASQLPTKLEFVARGGTGRSIKHTFRTVKVARRVPTLPPKKIEGASGGASGSGAPSQAAPERRQRRDRCKRHVCTICDKRYSSPGKLSQHILSHTGELPFSCDLCEKRFNSKFKLLRHGLIHSEARAFACTVCGKTFNRKDHLTNHVRVHNPVKKLHTCEWPGCRKSYTSLLSYRKHAALHSAEEGNLQCKICDQMFTSQQDIVYHLKVHTGSRTIKTETDKKYLCDHCDRRFFTAKDVRRHSVVHTGRRDFLCPHCPQKFGRKDHLVRHVKNAHPDESWRSAAVGTSKDPPLESTTIKECYTQYPVERSDFDIWKSSFSKEELEEGQTSVPASDIIVEMPQDLDIKVEPLEVEDSVEVKLEQPTSPSCEIIEYPVMYIVPPAYTHTPSDLPYITTQPLSDQLDAHLLTTENVESLLIDPGEGPSGLSSQMLGLLEESEQTYVSEEVRTQQRLPAFTQAFQTAQSPKPPLPPPPPH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00262114;
90% Identity: iTF_00926061;
80% Identity: -